STRINGSTRING
SNRPF SNRPF ENSUAMP00000009736 ENSUAMP00000009736 DDX42 DDX42 NCBP2L NCBP2L SF3B3 SF3B3 ENSUAMP00000006861 ENSUAMP00000006861 NCBP1 NCBP1 ENSUAMP00000005947 ENSUAMP00000005947 POLR2H POLR2H TXNL4A TXNL4A SNRNP48 SNRNP48 ENSUAMP00000003688 ENSUAMP00000003688 ENSUAMP00000003643 ENSUAMP00000003643 ENSUAMP00000003633 ENSUAMP00000003633 ENSUAMP00000003566 ENSUAMP00000003566 POLR2J POLR2J ENSUAMP00000014226 ENSUAMP00000014226 SNRNP35 SNRNP35 SRSF2 SRSF2 SNRPD1 SNRPD1 SNRNP25 SNRNP25 DDX23 DDX23 SF3B5 SF3B5 ENSUAMP00000037248 ENSUAMP00000037248 ENSUAMP00000003527 ENSUAMP00000003527 PRPF6 PRPF6 ENSUAMP00000001138 ENSUAMP00000001138 EFTUD2 EFTUD2 ENSUAMP00000000999 ENSUAMP00000000999 ENSUAMP00000000623 ENSUAMP00000000623 ENSUAMP00000000492 ENSUAMP00000000492 ENSUAMP00000026961 ENSUAMP00000026961 ENSUAMP00000028028 ENSUAMP00000028028 ENSUAMP00000028455 ENSUAMP00000028455 SNRPD2-2 SNRPD2-2 SF3B4 SF3B4 SNRPD2-3 SNRPD2-3 NCBP2 NCBP2 POLR2C POLR2C YBX2 YBX2 POLR2A POLR2A ENSUAMP00000019533 ENSUAMP00000019533 ZMAT5 ZMAT5 ENSUAMP00000019788 ENSUAMP00000019788 ENSUAMP00000020754 ENSUAMP00000020754 ZRSR2 ZRSR2 YBX3 YBX3 SNRNP40 SNRNP40 ENSUAMP00000023803 ENSUAMP00000023803 SF3B1 SF3B1 GTF2F2 GTF2F2 ENSUAMP00000025480 ENSUAMP00000025480 ENSUAMP00000026187 ENSUAMP00000026187 POLR2F POLR2F POLR2I POLR2I SF3B2 SF3B2 SNRPD3 SNRPD3 POLR2G POLR2G ENSUAMP00000033911 ENSUAMP00000033911 ENSUAMP00000033230 ENSUAMP00000033230 ENSUAMP00000032859 ENSUAMP00000032859 ENSUAMP00000032400 ENSUAMP00000032400 POLR2D POLR2D SNRPE SNRPE ENSUAMP00000012147 ENSUAMP00000012147 POLR2E POLR2E ENSUAMP00000010169 ENSUAMP00000010169 ENSUAMP00000010166 ENSUAMP00000010166 ENSUAMP00000010072 ENSUAMP00000010072 GTF2F1 GTF2F1 SNRPD2 SNRPD2 ENSUAMP00000009903 ENSUAMP00000009903
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SNRPFSm domain-containing protein. (86 aa)
ENSUAMP00000009736Uncharacterized protein. (71 aa)
DDX42DEAD-box helicase 42. (935 aa)
NCBP2LNuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (162 aa)
SF3B3Splicing factor 3b subunit 3. (1217 aa)
ENSUAMP00000006861Sm domain-containing protein. (52 aa)
NCBP1Nuclear cap binding protein subunit 1. (790 aa)
ENSUAMP00000005947annotation not available (78 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
TXNL4AThioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (188 aa)
SNRNP48Small nuclear ribonucleoprotein U11/U12 subunit 48. (338 aa)
ENSUAMP00000003688Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (78 aa)
ENSUAMP00000003643Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (72 aa)
ENSUAMP00000003633Uncharacterized protein. (444 aa)
ENSUAMP00000003566Uncharacterized protein; Belongs to the RNA polymerase beta chain family. (942 aa)
POLR2JRNA polymerase II subunit J. (117 aa)
ENSUAMP00000014226RRM domain-containing protein. (148 aa)
SNRNP35Small nuclear ribonucleoprotein U11/U12 subunit 35. (246 aa)
SRSF2RRM domain-containing protein. (221 aa)
SNRPD1Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (117 aa)
SNRNP25Small nuclear ribonucleoprotein U11/U12 subunit 25. (123 aa)
DDX23DEAD-box helicase 23. (820 aa)
SF3B5Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
ENSUAMP00000037248MPN domain-containing protein. (979 aa)
ENSUAMP00000003527Uncharacterized protein. (72 aa)
PRPF6Pre-mRNA processing factor 6. (758 aa)
ENSUAMP00000001138Sm domain-containing protein. (85 aa)
EFTUD2Elongation factor Tu GTP binding domain containing 2. (970 aa)
ENSUAMP00000000999RRM domain-containing protein. (126 aa)
ENSUAMP00000000623Uncharacterized protein. (86 aa)
ENSUAMP00000000492CSD_1 domain-containing protein. (355 aa)
ENSUAMP00000026961Uncharacterized protein. (113 aa)
ENSUAMP00000028028Sm domain-containing protein. (48 aa)
ENSUAMP00000028455Uncharacterized protein. (71 aa)
SNRPD2-2Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (123 aa)
SF3B4Splicing factor 3b subunit 4. (424 aa)
SNRPD2-3Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (118 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (163 aa)
POLR2CRNA polymerase II subunit C. (275 aa)
YBX2Y-box binding protein 2. (265 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1837 aa)
ENSUAMP00000019533CSD domain-containing protein. (311 aa)
ZMAT5Zinc finger matrin-type 5. (170 aa)
ENSUAMP00000019788Uncharacterized protein. (1338 aa)
ENSUAMP00000020754Uncharacterized protein. (105 aa)
ZRSR2Zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2. (301 aa)
YBX3Y-box binding protein 3. (273 aa)
SNRNP40Small nuclear ribonucleoprotein U5 subunit 40. (358 aa)
ENSUAMP00000023803CSP domain-containing protein. (311 aa)
SF3B1Splicing factor 3b subunit 1. (1122 aa)
GTF2F2General transcription factor IIF subunit 2. (241 aa)
ENSUAMP00000025480Uncharacterized protein. (157 aa)
ENSUAMP00000026187Sm domain-containing protein. (72 aa)
POLR2FRNA polymerase II subunit F. (127 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
SF3B2Splicing factor 3b subunit 2. (910 aa)
SNRPD3Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (126 aa)
POLR2GRNA polymerase II subunit G. (241 aa)
ENSUAMP00000033911Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa)
ENSUAMP00000033230RRM domain-containing protein. (125 aa)
ENSUAMP00000032859Uncharacterized protein. (137 aa)
ENSUAMP00000032400Uncharacterized protein. (67 aa)
POLR2DRNA polymerase II subunit D. (132 aa)
SNRPESmall nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (88 aa)
ENSUAMP00000012147Uncharacterized protein. (248 aa)
POLR2ERNA polymerase II subunit E. (294 aa)
ENSUAMP00000010169Uncharacterized protein. (1045 aa)
ENSUAMP00000010166SEC63 domain-containing protein. (329 aa)
ENSUAMP00000010072Sm domain-containing protein. (105 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (538 aa)
SNRPD2Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (53 aa)
ENSUAMP00000009903Uncharacterized protein. (150 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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