STRINGSTRING
GMPR GMPR ENSUAMP00000004451 ENSUAMP00000004451 AMPD2 AMPD2 HPRT1 HPRT1 ADK ADK DGUOK DGUOK ADA ADA AMPD1 AMPD1 AMPD3 AMPD3 ENSUAMP00000028238 ENSUAMP00000028238 ADAL ADAL GMPR2 GMPR2 APRT APRT DCK DCK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GMPRGMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (291 aa)
ENSUAMP00000004451IMPDH domain-containing protein. (161 aa)
AMPD2AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (799 aa)
HPRT1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (215 aa)
ADKAdenosine kinase. (311 aa)
DGUOKDeoxyguanosine kinase. (291 aa)
ADAAdenosine deaminase. (385 aa)
AMPD1AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (743 aa)
AMPD3AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (775 aa)
ENSUAMP00000028238PNP_UDP_1 domain-containing protein. (96 aa)
ADALAdenosine deaminase like. (396 aa)
GMPR2GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (348 aa)
APRTAdenine phosphoribosyltransferase. (180 aa)
DCKDeoxycytidine kinase. (260 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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