STRINGSTRING
CCND1 CCND1 PSME1 PSME1 PSMA6 PSMA6 PSMC6 PSMC6 PSMB10 PSMB10 ENSUAMP00000026056 ENSUAMP00000026056 PSMA1 PSMA1 ENSUAMP00000025192 ENSUAMP00000025192 PSMC2 PSMC2 PSMB4 PSMB4 PSMA4 PSMA4 ENSUAMP00000022022 ENSUAMP00000022022 ENSUAMP00000021443 ENSUAMP00000021443 PSMD5 PSMD5 ENSUAMP00000020715 ENSUAMP00000020715 KXD1 KXD1 PSMD10 PSMD10 ENSUAMP00000037175 ENSUAMP00000037175 PSMD12 PSMD12 ENSUAMP00000036637 ENSUAMP00000036637 PSMD4 PSMD4 PSMA2 PSMA2 PSMB7 PSMB7 PSMA7 PSMA7 PSMD3 PSMD3 PSMD8 PSMD8 PSMB9 PSMB9 PSMB8 PSMB8 PSMD13 PSMD13 PSME3 PSME3 CDK4 CDK4 ENSUAMP00000012220 ENSUAMP00000012220 PSMD9 PSMD9 PSMB5 PSMB5 ENSUAMP00000010232 ENSUAMP00000010232 PSME4 PSME4 PSMD7 PSMD7 PSMA3 PSMA3 PSMC5 PSMC5 PSMF1 PSMF1 PSMB11 PSMB11 PSMB3 PSMB3 PSMB6 PSMB6 PSMC3 PSMC3 ENSUAMP00000005735 ENSUAMP00000005735 ENSUAMP00000004531 ENSUAMP00000004531 PSMB1 PSMB1 ENSUAMP00000003372 ENSUAMP00000003372 PSMD11 PSMD11 PSMD2 PSMD2 PSMD1 PSMD1 PSMC4 PSMC4 PSMB2 PSMB2 ENSUAMP00000000292 ENSUAMP00000000292 PSME2 PSME2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CCND1Cyclin D1; Belongs to the cyclin family. (294 aa)
PSME1Proteasome activator subunit 1. (249 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa)
PSMB10Proteasome subunit beta 10. (327 aa)
ENSUAMP00000026056MitMem_reg domain-containing protein. (95 aa)
PSMA1Proteasome subunit alpha type. (269 aa)
ENSUAMP00000025192Ubiquitin-like domain-containing protein. (156 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
ENSUAMP00000022022Uncharacterized protein. (107 aa)
ENSUAMP00000021443Ubiquitin-like domain-containing protein. (77 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
ENSUAMP00000020715Ubiquitin-like domain-containing protein. (132 aa)
KXD1KxDL motif containing 1. (128 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (151 aa)
ENSUAMP00000037175MPN domain-containing protein. (156 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
ENSUAMP00000036637PCI domain-containing protein. (405 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (344 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PSMB7Proteasome subunit beta. (277 aa)
PSMA7Proteasome endopeptidase complex. (248 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (536 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (351 aa)
PSMB9Proteasome subunit beta. (220 aa)
PSMB8Proteasome subunit beta. (276 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (376 aa)
PSME3Proteasome activator subunit 3. (254 aa)
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (340 aa)
ENSUAMP00000012220ATPase_AAA_core domain-containing protein. (174 aa)
PSMD9PDZ domain-containing protein. (309 aa)
PSMB5Proteasome subunit beta. (263 aa)
ENSUAMP00000010232Ubiquitin-like domain-containing protein. (88 aa)
PSME4Proteasome activator subunit 4. (1436 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (322 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
PSMB11Proteasome subunit beta. (292 aa)
PSMB3Proteasome subunit beta. (202 aa)
PSMB6Proteasome subunit beta. (219 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (439 aa)
ENSUAMP00000005735PROTEASOME_ALPHA_1 domain-containing protein. (80 aa)
ENSUAMP00000004531AAA domain-containing protein; Belongs to the AAA ATPase family. (421 aa)
PSMB1Proteasome subunit beta. (241 aa)
ENSUAMP00000003372Uncharacterized protein. (157 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (418 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (683 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (400 aa)
PSMB2Proteasome subunit beta. (167 aa)
ENSUAMP00000000292PCI domain-containing protein. (389 aa)
PSME2Proteasome activator subunit 2. (239 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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