33 items (Ursus americanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSUAMP00000001398	Uncharacterized protein. (73 aa)
	ESR1	Estrogen receptor 1. (490 aa)
	PITX2	Homeobox protein. (325 aa)
	ENSUAMP00000013226	Cys_knot domain-containing protein. (140 aa)
	ENSUAMP00000013585	Uncharacterized protein. (588 aa)
	ATAD2	ATPase family AAA domain containing 2. (1383 aa)
	ENSUAMP00000020461	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (824 aa)
	KCTD15	Potassium channel tetramerization domain containing 15. (283 aa)
	TFAP2C	Transcription factor AP-2 gamma. (475 aa)
	PITX1	Homeobox protein. (313 aa)
	CITED2	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
	ENSUAMP00000023384	Rad60-SLD domain-containing protein. (67 aa)
	CITED1	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (195 aa)
	ENSUAMP00000023518	Small ubiquitin-related modifier. (101 aa)
	TFAP2A	Transcription factor AP-2 alpha. (442 aa)
	ENSUAMP00000026178	BTB domain-containing protein. (846 aa)
	TFAP2D	Transcription factor AP-2 delta. (452 aa)
	TFAP2B	Transcription factor AP-2 beta. (460 aa)
	ENSUAMP00000030460	WW domain-containing protein. (139 aa)
	ENSUAMP00000030496	Bromo domain-containing protein. (659 aa)
	YEATS4	YEATS domain containing 4. (227 aa)
	ENSUAMP00000030709	Nucleoplasmin domain-containing protein. (268 aa)
	CREBBP	CREB binding protein. (2333 aa)
	MYC	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa)
	EP300	E1A binding protein p300. (2399 aa)
	KDM5B	Lysine demethylase 5B. (1039 aa)
	ENSUAMP00000032917	Uncharacterized protein. (117 aa)
	ENSUAMP00000032989	Uncharacterized protein. (217 aa)
	ENSUAMP00000033470	Ubiquitin-like domain-containing protein. (101 aa)
	MYBL2	MYB proto-oncogene like 2. (699 aa)
	CGA	Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (120 aa)
	DEK	DEK proto-oncogene. (351 aa)
	PITX3	Homeobox protein. (302 aa)

Your Current Organism:

Ursus americanus

NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATAD2	ESR1	ENSUAMP00000014822	ENSUAMP00000006270	ATPase family AAA domain containing 2.	Estrogen receptor 1.	0.938
CGA	ENSUAMP00000013226	ENSUAMP00000036079	ENSUAMP00000013226	Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family.	Cys_knot domain-containing protein.	0.980
CITED1	CREBBP	ENSUAMP00000023505	ENSUAMP00000030777	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1.	CREB binding protein.	0.675
CITED1	EP300	ENSUAMP00000023505	ENSUAMP00000031856	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1.	E1A binding protein p300.	0.921
CITED1	ESR1	ENSUAMP00000023505	ENSUAMP00000006270	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1.	Estrogen receptor 1.	0.518
CITED1	TFAP2A	ENSUAMP00000023505	ENSUAMP00000024076	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1.	Transcription factor AP-2 alpha.	0.522
CITED1	TFAP2B	ENSUAMP00000023505	ENSUAMP00000030390	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1.	Transcription factor AP-2 beta.	0.524
CITED1	TFAP2C	ENSUAMP00000023505	ENSUAMP00000022377	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1.	Transcription factor AP-2 gamma.	0.578
CITED1	TFAP2D	ENSUAMP00000023505	ENSUAMP00000030378	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1.	Transcription factor AP-2 delta.	0.522
CITED2	CREBBP	ENSUAMP00000022802	ENSUAMP00000030777	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2.	CREB binding protein.	0.940
CITED2	EP300	ENSUAMP00000022802	ENSUAMP00000031856	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2.	E1A binding protein p300.	0.953
CITED2	TFAP2A	ENSUAMP00000022802	ENSUAMP00000024076	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2.	Transcription factor AP-2 alpha.	0.588
CITED2	TFAP2B	ENSUAMP00000022802	ENSUAMP00000030390	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2.	Transcription factor AP-2 beta.	0.526
CITED2	TFAP2C	ENSUAMP00000022802	ENSUAMP00000022377	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2.	Transcription factor AP-2 gamma.	0.526
CITED2	TFAP2D	ENSUAMP00000022802	ENSUAMP00000030378	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2.	Transcription factor AP-2 delta.	0.633
CREBBP	CITED1	ENSUAMP00000030777	ENSUAMP00000023505	CREB binding protein.	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1.	0.675
CREBBP	CITED2	ENSUAMP00000030777	ENSUAMP00000022802	CREB binding protein.	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2.	0.940
CREBBP	DEK	ENSUAMP00000030777	ENSUAMP00000036861	CREB binding protein.	DEK proto-oncogene.	0.493
CREBBP	ENSUAMP00000001398	ENSUAMP00000030777	ENSUAMP00000001398	CREB binding protein.	Uncharacterized protein.	0.794
CREBBP	ENSUAMP00000023384	ENSUAMP00000030777	ENSUAMP00000023384	CREB binding protein.	Rad60-SLD domain-containing protein.	0.794