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UCKL1 UCKL1 DCK DCK APRT APRT GMPR2 GMPR2 ADAL ADAL ENSUAMP00000028238 ENSUAMP00000028238 AMPD3 AMPD3 TK1 TK1 DGUOK DGUOK GMPR GMPR ENSUAMP00000004451 ENSUAMP00000004451 TK2 TK2 AMPD2 AMPD2 UCK1 UCK1 HPRT1 HPRT1 CDA CDA UCK2 UCK2 UPP1 UPP1 ADK ADK ADA ADA PUDP PUDP AMPD1 AMPD1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UCKL1Uridine-cytidine kinase; Belongs to the uridine kinase family. (547 aa)
DCKDeoxycytidine kinase. (260 aa)
APRTAdenine phosphoribosyltransferase. (180 aa)
GMPR2GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (348 aa)
ADALAdenosine deaminase like. (396 aa)
ENSUAMP00000028238PNP_UDP_1 domain-containing protein. (96 aa)
AMPD3AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (775 aa)
TK1Thymidine kinase. (239 aa)
DGUOKDeoxyguanosine kinase. (291 aa)
GMPRGMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (291 aa)
ENSUAMP00000004451IMPDH domain-containing protein. (161 aa)
TK2Thymidine kinase 2. (216 aa)
AMPD2AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (799 aa)
UCK1Uridine-cytidine kinase; Belongs to the uridine kinase family. (276 aa)
HPRT1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (215 aa)
CDACytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (146 aa)
UCK2Uridine-cytidine kinase; Belongs to the uridine kinase family. (261 aa)
UPP1Uridine phosphorylase 1. (316 aa)
ADKAdenosine kinase. (311 aa)
ADAAdenosine deaminase. (385 aa)
PUDPPseudouridine 5'-phosphatase. (216 aa)
AMPD1AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (743 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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