22 items (Ursus americanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NCOA1	Nuclear receptor coactivator. (1441 aa)
	HDAC3	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
	RXRB	Retinoid X receptor beta. (532 aa)
	ENSUAMP00000034574	Uncharacterized protein. (525 aa)
	EP300	E1A binding protein p300. (2399 aa)
	NCOR2	Nuclear receptor corepressor 2. (2465 aa)
	PLIN1	Perilipin; Belongs to the perilipin family. (507 aa)
	ABCA2	ATP binding cassette subfamily A member 2. (2053 aa)
	RXRA	Retinoid X receptor alpha. (469 aa)
	ENSUAMP00000025261	GPS2_interact domain-containing protein. (204 aa)
	NCOR1	Nuclear receptor corepressor 1. (2267 aa)
	ENSUAMP00000024197	ABC transporter domain-containing protein. (288 aa)
	ENSUAMP00000024187	Uncharacterized protein. (155 aa)
	ENSUAMP00000022260	Uncharacterized protein. (154 aa)
	TBL1XR1	Transducin beta like 1 X-linked receptor 1. (520 aa)
	NR1H2	Nuclear receptor subfamily 1 group H member 2. (455 aa)
	GPS2	G protein pathway suppressor 2. (338 aa)
	ARL4A	ADP ribosylation factor like GTPase 4A. (200 aa)
	ENSUAMP00000011110	ABC transporter domain-containing protein. (652 aa)
	ARL4C	ADP ribosylation factor like GTPase 4C; Belongs to the small GTPase superfamily. Arf family. (192 aa)
	TNRC6B	Trinucleotide repeat containing adaptor 6B. (1802 aa)
	NR1H3	Nuclear receptor subfamily 1 group H member 3. (447 aa)

Your Current Organism:

Ursus americanus

NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA2	ENSUAMP00000024187	ENSUAMP00000029385	ENSUAMP00000024187	ATP binding cassette subfamily A member 2.	Uncharacterized protein.	0.554
ABCA2	NR1H2	ENSUAMP00000029385	ENSUAMP00000018908	ATP binding cassette subfamily A member 2.	Nuclear receptor subfamily 1 group H member 2.	0.853
ABCA2	NR1H3	ENSUAMP00000029385	ENSUAMP00000003082	ATP binding cassette subfamily A member 2.	Nuclear receptor subfamily 1 group H member 3.	0.647
ABCA2	RXRA	ENSUAMP00000029385	ENSUAMP00000026794	ATP binding cassette subfamily A member 2.	Retinoid X receptor alpha.	0.813
ENSUAMP00000011110	ENSUAMP00000024187	ENSUAMP00000011110	ENSUAMP00000024187	ABC transporter domain-containing protein.	Uncharacterized protein.	0.825
ENSUAMP00000011110	NR1H2	ENSUAMP00000011110	ENSUAMP00000018908	ABC transporter domain-containing protein.	Nuclear receptor subfamily 1 group H member 2.	0.853
ENSUAMP00000011110	NR1H3	ENSUAMP00000011110	ENSUAMP00000003082	ABC transporter domain-containing protein.	Nuclear receptor subfamily 1 group H member 3.	0.647
ENSUAMP00000011110	RXRA	ENSUAMP00000011110	ENSUAMP00000026794	ABC transporter domain-containing protein.	Retinoid X receptor alpha.	0.813
ENSUAMP00000022260	ENSUAMP00000025261	ENSUAMP00000022260	ENSUAMP00000025261	Uncharacterized protein.	GPS2_interact domain-containing protein.	0.822
ENSUAMP00000022260	ENSUAMP00000034574	ENSUAMP00000022260	ENSUAMP00000034574	Uncharacterized protein.	Uncharacterized protein.	0.939
ENSUAMP00000022260	EP300	ENSUAMP00000022260	ENSUAMP00000031856	Uncharacterized protein.	E1A binding protein p300.	0.468
ENSUAMP00000022260	HDAC3	ENSUAMP00000022260	ENSUAMP00000037450	Uncharacterized protein.	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.970
ENSUAMP00000022260	NCOA1	ENSUAMP00000022260	ENSUAMP00000008682	Uncharacterized protein.	Nuclear receptor coactivator.	0.434
ENSUAMP00000022260	NCOR1	ENSUAMP00000022260	ENSUAMP00000025256	Uncharacterized protein.	Nuclear receptor corepressor 1.	0.822
ENSUAMP00000022260	NCOR2	ENSUAMP00000022260	ENSUAMP00000030789	Uncharacterized protein.	Nuclear receptor corepressor 2.	0.826
ENSUAMP00000022260	NR1H2	ENSUAMP00000022260	ENSUAMP00000018908	Uncharacterized protein.	Nuclear receptor subfamily 1 group H member 2.	0.500
ENSUAMP00000022260	NR1H3	ENSUAMP00000022260	ENSUAMP00000003082	Uncharacterized protein.	Nuclear receptor subfamily 1 group H member 3.	0.500
ENSUAMP00000022260	RXRA	ENSUAMP00000022260	ENSUAMP00000026794	Uncharacterized protein.	Retinoid X receptor alpha.	0.502
ENSUAMP00000022260	RXRB	ENSUAMP00000022260	ENSUAMP00000035462	Uncharacterized protein.	Retinoid X receptor beta.	0.516
ENSUAMP00000022260	TBL1XR1	ENSUAMP00000022260	ENSUAMP00000019057	Uncharacterized protein.	Transducin beta like 1 X-linked receptor 1.	0.939