9 items (Ursus americanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EP300	E1A binding protein p300. (2399 aa)
	ENSUAMP00000000300	Bromo domain-containing protein. (84 aa)
	FOXO1	Forkhead box O1. (660 aa)
	KAT2B	Lysine acetyltransferase 2B. (629 aa)
	FOXO3	Forkhead box O3. (453 aa)
	FOXO3B	Forkhead box O3B. (244 aa)
	SIRT3	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (374 aa)
	SIRT1	Sirtuin 1. (618 aa)
	CREBBP	CREB binding protein. (2333 aa)

Your Current Organism:

Ursus americanus

NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CREBBP	ENSUAMP00000000300	ENSUAMP00000030777	ENSUAMP00000000300	CREB binding protein.	Bromo domain-containing protein.	0.948
CREBBP	EP300	ENSUAMP00000030777	ENSUAMP00000031856	CREB binding protein.	E1A binding protein p300.	0.997
CREBBP	FOXO1	ENSUAMP00000030777	ENSUAMP00000004446	CREB binding protein.	Forkhead box O1.	0.969
CREBBP	FOXO3	ENSUAMP00000030777	ENSUAMP00000012151	CREB binding protein.	Forkhead box O3.	0.835
CREBBP	FOXO3B	ENSUAMP00000030777	ENSUAMP00000012153	CREB binding protein.	Forkhead box O3B.	0.835
CREBBP	KAT2B	ENSUAMP00000030777	ENSUAMP00000005141	CREB binding protein.	Lysine acetyltransferase 2B.	0.948
CREBBP	SIRT1	ENSUAMP00000030777	ENSUAMP00000021491	CREB binding protein.	Sirtuin 1.	0.622
ENSUAMP00000000300	CREBBP	ENSUAMP00000000300	ENSUAMP00000030777	Bromo domain-containing protein.	CREB binding protein.	0.948
ENSUAMP00000000300	EP300	ENSUAMP00000000300	ENSUAMP00000031856	Bromo domain-containing protein.	E1A binding protein p300.	0.948
ENSUAMP00000000300	FOXO1	ENSUAMP00000000300	ENSUAMP00000004446	Bromo domain-containing protein.	Forkhead box O1.	0.407
ENSUAMP00000000300	FOXO3	ENSUAMP00000000300	ENSUAMP00000012151	Bromo domain-containing protein.	Forkhead box O3.	0.733
ENSUAMP00000000300	FOXO3B	ENSUAMP00000000300	ENSUAMP00000012153	Bromo domain-containing protein.	Forkhead box O3B.	0.733
ENSUAMP00000000300	KAT2B	ENSUAMP00000000300	ENSUAMP00000005141	Bromo domain-containing protein.	Lysine acetyltransferase 2B.	0.897
ENSUAMP00000000300	SIRT1	ENSUAMP00000000300	ENSUAMP00000021491	Bromo domain-containing protein.	Sirtuin 1.	0.444
EP300	CREBBP	ENSUAMP00000031856	ENSUAMP00000030777	E1A binding protein p300.	CREB binding protein.	0.997
EP300	ENSUAMP00000000300	ENSUAMP00000031856	ENSUAMP00000000300	E1A binding protein p300.	Bromo domain-containing protein.	0.948
EP300	FOXO1	ENSUAMP00000031856	ENSUAMP00000004446	E1A binding protein p300.	Forkhead box O1.	0.750
EP300	FOXO3	ENSUAMP00000031856	ENSUAMP00000012151	E1A binding protein p300.	Forkhead box O3.	0.911
EP300	FOXO3B	ENSUAMP00000031856	ENSUAMP00000012153	E1A binding protein p300.	Forkhead box O3B.	0.911
EP300	KAT2B	ENSUAMP00000031856	ENSUAMP00000005141	E1A binding protein p300.	Lysine acetyltransferase 2B.	0.948