STRINGSTRING
ENSUAMP00000022722 ENSUAMP00000022722 ABCC4 ABCC4 SETBP1 SETBP1 ENSUAMP00000028152 ENSUAMP00000028152 ENSUAMP00000031486 ENSUAMP00000031486 VAV1 VAV1 IMPDH2 IMPDH2 SLC29A1 SLC29A1 GUK1 GUK1 NUDT15 NUDT15 NME1 NME1 NME2 NME2 ENSUAMP00000008121 ENSUAMP00000008121 IMPDH1 IMPDH1 VAV2 VAV2 HPRT1 HPRT1 ENSUAMP00000012786 ENSUAMP00000012786 ENSUAMP00000012789 ENSUAMP00000012789 GMPS GMPS ENSUAMP00000019309 ENSUAMP00000019309 XDH XDH TPMT TPMT NME3 NME3 SLC28A3 SLC28A3 SLC29A2 SLC29A2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSUAMP00000022722Uncharacterized protein. (223 aa)
ABCC4ATP binding cassette subfamily C member 4. (942 aa)
SETBP1SET binding protein 1. (1298 aa)
ENSUAMP00000028152SH3 domain-containing protein. (120 aa)
ENSUAMP00000031486Calponin-homology (CH) domain-containing protein. (86 aa)
VAV1Vav guanine nucleotide exchange factor 1. (774 aa)
IMPDH2Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (514 aa)
SLC29A1Solute carrier family 29 member 1 (Augustine blood group). (456 aa)
GUK1Guanylate kinase 1. (219 aa)
NUDT15Nudix hydrolase 15. (176 aa)
NME1Nucleoside diphosphate kinase. (152 aa)
NME2Nucleoside diphosphate kinase. (159 aa)
ENSUAMP00000008121Nucleos_tra2_N domain-containing protein. (482 aa)
IMPDH1Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (609 aa)
VAV2Vav guanine nucleotide exchange factor 2. (855 aa)
HPRT1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (215 aa)
ENSUAMP00000012786ABC transporter domain-containing protein. (114 aa)
ENSUAMP00000012789Uncharacterized protein. (204 aa)
GMPSGuanine monophosphate synthase. (693 aa)
ENSUAMP00000019309Calponin-homology (CH) domain-containing protein. (82 aa)
XDHXanthine dehydrogenase. (1313 aa)
TPMTThiopurine S-methyltransferase. (220 aa)
NME3Nucleoside diphosphate kinase. (169 aa)
SLC28A3Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. (658 aa)
SLC29A2Solute carrier family 29 member 2. (456 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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