(17 nodes) IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation network (Ursus americanus)

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second shell of interactors

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Known Interactions

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Predicted Interactions

gene neighborhood

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Your Input:
	ENSUAMP00000001501	Uncharacterized protein. (470 aa)
	TAB2	TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (683 aa)
	TAB1	TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa)
	ENSUAMP00000006398	annotation not available (356 aa)
	ENSUAMP00000010232	Ubiquitin-like domain-containing protein. (88 aa)
	TICAM1	TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (751 aa)
	KXD1	KxDL motif containing 1. (128 aa)
	ENSUAMP00000020715	Ubiquitin-like domain-containing protein. (132 aa)
	ENSUAMP00000021443	Ubiquitin-like domain-containing protein. (77 aa)
	ENSUAMP00000025192	Ubiquitin-like domain-containing protein. (156 aa)
	ENSUAMP00000025678	Uncharacterized protein. (163 aa)
	ENSUAMP00000026449	Uncharacterized protein. (121 aa)
	TAB3	TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (717 aa)
	TRAF6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
	ENSUAMP00000031438	Protein kinase domain-containing protein. (456 aa)
	MAP3K7	Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
	IRAK2	Interleukin 1 receptor associated kinase 2. (621 aa)

Your Current Organism:

Ursus americanus

NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSUAMP00000001501	ENSUAMP00000025678	ENSUAMP00000001501	ENSUAMP00000025678	Uncharacterized protein.	Uncharacterized protein.	0.940
ENSUAMP00000006398	ENSUAMP00000025678	ENSUAMP00000006398	ENSUAMP00000025678	annotation not available	Uncharacterized protein.	0.940
ENSUAMP00000010232	ENSUAMP00000021443	ENSUAMP00000010232	ENSUAMP00000021443	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.998
ENSUAMP00000010232	ENSUAMP00000025192	ENSUAMP00000010232	ENSUAMP00000025192	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.999
ENSUAMP00000010232	ENSUAMP00000025678	ENSUAMP00000010232	ENSUAMP00000025678	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.400
ENSUAMP00000010232	ENSUAMP00000031438	ENSUAMP00000010232	ENSUAMP00000031438	Ubiquitin-like domain-containing protein.	Protein kinase domain-containing protein.	0.533
ENSUAMP00000010232	IRAK2	ENSUAMP00000010232	ENSUAMP00000032376	Ubiquitin-like domain-containing protein.	Interleukin 1 receptor associated kinase 2.	0.458
ENSUAMP00000010232	MAP3K7	ENSUAMP00000010232	ENSUAMP00000031907	Ubiquitin-like domain-containing protein.	Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.	0.559
ENSUAMP00000010232	TAB2	ENSUAMP00000010232	ENSUAMP00000002452	Ubiquitin-like domain-containing protein.	TGF-beta activated kinase 1 (MAP3K7) binding protein 2.	0.821
ENSUAMP00000010232	TAB3	ENSUAMP00000010232	ENSUAMP00000027450	Ubiquitin-like domain-containing protein.	TGF-beta activated kinase 1 (MAP3K7) binding protein 3.	0.711
ENSUAMP00000010232	TRAF6	ENSUAMP00000010232	ENSUAMP00000030320	Ubiquitin-like domain-containing protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.910
ENSUAMP00000020715	ENSUAMP00000021443	ENSUAMP00000020715	ENSUAMP00000021443	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.959
ENSUAMP00000020715	ENSUAMP00000025192	ENSUAMP00000020715	ENSUAMP00000025192	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.991
ENSUAMP00000020715	ENSUAMP00000031438	ENSUAMP00000020715	ENSUAMP00000031438	Ubiquitin-like domain-containing protein.	Protein kinase domain-containing protein.	0.533
ENSUAMP00000020715	IRAK2	ENSUAMP00000020715	ENSUAMP00000032376	Ubiquitin-like domain-containing protein.	Interleukin 1 receptor associated kinase 2.	0.458
ENSUAMP00000020715	MAP3K7	ENSUAMP00000020715	ENSUAMP00000031907	Ubiquitin-like domain-containing protein.	Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.	0.551
ENSUAMP00000020715	TAB2	ENSUAMP00000020715	ENSUAMP00000002452	Ubiquitin-like domain-containing protein.	TGF-beta activated kinase 1 (MAP3K7) binding protein 2.	0.821
ENSUAMP00000020715	TAB3	ENSUAMP00000020715	ENSUAMP00000027450	Ubiquitin-like domain-containing protein.	TGF-beta activated kinase 1 (MAP3K7) binding protein 3.	0.711
ENSUAMP00000020715	TRAF6	ENSUAMP00000020715	ENSUAMP00000030320	Ubiquitin-like domain-containing protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.910
ENSUAMP00000021443	ENSUAMP00000010232	ENSUAMP00000021443	ENSUAMP00000010232	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.998