STRINGSTRING
INSRR INSRR RSPO1 RSPO1 RSPO2 RSPO2 ENSUAMP00000032909 ENSUAMP00000032909 RSPO3 RSPO3 ENSUAMP00000011871 ENSUAMP00000011871 CRELD2 CRELD2 FURIN FURIN CRELD1 CRELD1 ERBB2 ERBB2 RSPO4 RSPO4 ERBB3 ERBB3 IGF1R IGF1R
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
INSRRTyrosine-protein kinase receptor. (1318 aa)
RSPO1R-spondin 1. (263 aa)
RSPO2R-spondin 2. (220 aa)
ENSUAMP00000032909Uncharacterized protein. (592 aa)
RSPO3R-spondin 3. (275 aa)
ENSUAMP00000011871PLAC domain-containing protein. (308 aa)
CRELD2Cysteine rich with EGF like domains 2. (406 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (793 aa)
CRELD1Cysteine rich with EGF like domains 1. (531 aa)
ERBB2Receptor protein-tyrosine kinase. (1261 aa)
RSPO4R-spondin 4. (229 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1281 aa)
IGF1RTyrosine-protein kinase receptor. (1288 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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