STRINGSTRING
ENSUAMP00000032699 ENSUAMP00000032699 HSD17B12 HSD17B12 ENSUAMP00000000227 ENSUAMP00000000227 ARSD ARSD ENSUAMP00000001312 ENSUAMP00000001312 CYP19A1 CYP19A1 ENSUAMP00000002638 ENSUAMP00000002638 ENSUAMP00000006303 ENSUAMP00000006303 ENSUAMP00000006803 ENSUAMP00000006803 ENSUAMP00000007016 ENSUAMP00000007016 ENSUAMP00000007027 ENSUAMP00000007027 ENSUAMP00000007219 ENSUAMP00000007219 CYP7B1 CYP7B1 STS STS ENSUAMP00000008515 ENSUAMP00000008515 AKR1C8P AKR1C8P HSD17B1 HSD17B1 UGT1A1 UGT1A1 ENSUAMP00000012176 ENSUAMP00000012176 ENSUAMP00000012528 ENSUAMP00000012528 CYP2B6 CYP2B6 SULT2B1 SULT2B1 COMT COMT SRD5A2 SRD5A2 ENSUAMP00000014595 ENSUAMP00000014595 ENSUAMP00000015867 ENSUAMP00000015867 ENSUAMP00000015869 ENSUAMP00000015869 ENSUAMP00000017348 ENSUAMP00000017348 CYP1B1 CYP1B1 AKR1D1 AKR1D1 ENSUAMP00000020160 ENSUAMP00000020160 ENSUAMP00000020162 ENSUAMP00000020162 HSD11B1 HSD11B1 ENSUAMP00000021744 ENSUAMP00000021744 SRD5A3 SRD5A3 ENSUAMP00000023141 ENSUAMP00000023141 ENSUAMP00000027938 ENSUAMP00000027938 ENSUAMP00000028019 ENSUAMP00000028019 HSD17B6 HSD17B6 CYP21A2 CYP21A2 DHRS11 DHRS11 CYP11A1 CYP11A1 HSD11B1L HSD11B1L ENSUAMP00000032152 ENSUAMP00000032152 SRD5A1 SRD5A1 ENSUAMP00000032777 ENSUAMP00000032777 ENSUAMP00000032778 ENSUAMP00000032778 HSD17B2 HSD17B2 ENSUAMP00000033863 ENSUAMP00000033863 CYP2E1 CYP2E1 ARSF ARSF ARSH ARSH ENSUAMP00000034027 ENSUAMP00000034027 ENSUAMP00000034638 ENSUAMP00000034638 ENSUAMP00000034639 ENSUAMP00000034639 CYP17A1 CYP17A1 CYP1A1 CYP1A1 CYP1A2 CYP1A2 HSD17B8 HSD17B8 ENSUAMP00000036081 ENSUAMP00000036081 ENSUAMP00000036091 ENSUAMP00000036091
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSUAMP000000326993Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (373 aa)
HSD17B12Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (227 aa)
ENSUAMP00000000227Uncharacterized protein. (123 aa)
ARSDArylsulfatase D. (612 aa)
ENSUAMP00000001312Sulfotransferase; Belongs to the sulfotransferase 1 family. (312 aa)
CYP19A1Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. (465 aa)
ENSUAMP00000002638Uncharacterized protein. (76 aa)
ENSUAMP00000006303Uncharacterized protein; Belongs to the cytochrome P450 family. (171 aa)
ENSUAMP00000006803Uncharacterized protein; Belongs to the cytochrome P450 family. (262 aa)
ENSUAMP00000007016Uncharacterized protein. (241 aa)
ENSUAMP00000007027Uncharacterized protein. (81 aa)
ENSUAMP00000007219GDT1 family protein. (141 aa)
CYP7B1Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (485 aa)
STSSteroid sulfatase. (602 aa)
ENSUAMP00000008515Uncharacterized protein. (148 aa)
AKR1C8PAldo-keto reductase family 1 member C8, pseudogene. (324 aa)
HSD17B1Hydroxysteroid 17-beta dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (312 aa)
UGT1A1UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (533 aa)
ENSUAMP00000012176Uncharacterized protein. (507 aa)
ENSUAMP00000012528Uncharacterized protein; Belongs to the cytochrome P450 family. (500 aa)
CYP2B6Cytochrome P450 family 2 subfamily B member 6; Belongs to the cytochrome P450 family. (436 aa)
SULT2B1Sulfotransferase; Belongs to the sulfotransferase 1 family. (333 aa)
COMTCatechol-O-methyltransferase. (334 aa)
SRD5A23-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (254 aa)
ENSUAMP00000014595UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (527 aa)
ENSUAMP00000015867Sulfotransferase; Belongs to the sulfotransferase 1 family. (307 aa)
ENSUAMP00000015869Sulfotransferase; Belongs to the sulfotransferase 1 family. (310 aa)
ENSUAMP00000017348Uncharacterized protein; Belongs to the cytochrome P450 family. (339 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa)
AKR1D1Aldo-keto reductase family 1 member D1. (323 aa)
ENSUAMP00000020160Uncharacterized protein. (375 aa)
ENSUAMP00000020162Uncharacterized protein. (830 aa)
HSD11B1Hydroxysteroid 11-beta dehydrogenase 1. (292 aa)
ENSUAMP00000021744Uncharacterized protein. (353 aa)
SRD5A3Steroid 5 alpha-reductase 3. (318 aa)
ENSUAMP00000023141Uncharacterized protein. (76 aa)
ENSUAMP00000027938Uncharacterized protein. (110 aa)
ENSUAMP00000028019Uncharacterized protein. (163 aa)
HSD17B6Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (314 aa)
CYP21A2Cytochrome P450 family 21 subfamily A member 2; Belongs to the cytochrome P450 family. (493 aa)
DHRS11Dehydrogenase/reductase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (332 aa)
CYP11A1Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (482 aa)
HSD11B1LHydroxysteroid 11-beta dehydrogenase 1 like. (291 aa)
ENSUAMP00000032152Uncharacterized protein. (503 aa)
SRD5A13-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (255 aa)
ENSUAMP00000032777Uncharacterized protein. (323 aa)
ENSUAMP00000032778Sulfotransferase; Belongs to the sulfotransferase 1 family. (171 aa)
HSD17B2Hydroxysteroid 17-beta dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (380 aa)
ENSUAMP00000033863Uncharacterized protein; Belongs to the cytochrome P450 family. (496 aa)
CYP2E1Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family. (494 aa)
ARSFArylsulfatase F. (584 aa)
ARSHArylsulfatase family member H. (562 aa)
ENSUAMP00000034027Sulfatase domain-containing protein. (592 aa)
ENSUAMP00000034638Uncharacterized protein; Belongs to the cytochrome P450 family. (490 aa)
ENSUAMP00000034639Uncharacterized protein. (463 aa)
CYP17A1Cytochrome P450 family 17 subfamily A member 1; Belongs to the cytochrome P450 family. (356 aa)
CYP1A1Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. (516 aa)
CYP1A2Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family. (512 aa)
HSD17B8Hydroxysteroid 17-beta dehydrogenase 8. (259 aa)
ENSUAMP00000036081Uncharacterized protein. (192 aa)
ENSUAMP00000036091Uncharacterized protein. (259 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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