STRINGSTRING
UCK2 UCK2 SLC25A42 SLC25A42 NT5C1A NT5C1A UMPS UMPS UCKL1 UCKL1 DUT DUT UPRT UPRT ENSUAMP00000002190 ENSUAMP00000002190 ENSUAMP00000002369 ENSUAMP00000002369 ENSUAMP00000002379 ENSUAMP00000002379 ENSUAMP00000002393 ENSUAMP00000002393 TYMS TYMS GOLT1B GOLT1B ENSUAMP00000004727 ENSUAMP00000004727 NME1 NME1 NME2 NME2 DCTPP1 DCTPP1 CANT1 CANT1 ENTPD5 ENTPD5 NUDT2 NUDT2 NT5M NT5M CDADC1 CDADC1 ENSUAMP00000007133 ENSUAMP00000007133 ENSUAMP00000007917 ENSUAMP00000007917 TK2 TK2 CAD CAD ENTPD4 ENTPD4 TTLL1 TTLL1 CTPS2 CTPS2 ENSUAMP00000009640 ENSUAMP00000009640 DTYMK DTYMK HSPE1 HSPE1 UCK1 UCK1 ENPP1 ENPP1 TLCD3A TLCD3A NUDT11 NUDT11 ENSUAMP00000012079 ENSUAMP00000012079 TLCD4-RWDD3 TLCD4-RWDD3 NT5C NT5C UPB1 UPB1 NT5E NT5E ENSUAMP00000014130 ENSUAMP00000014130 HDDC2 HDDC2 CDA CDA ENSUAMP00000015279 ENSUAMP00000015279 ENSUAMP00000016204 ENSUAMP00000016204 SPSB4 SPSB4 DCTD DCTD TTLL5 TTLL5 NME3 NME3 MRPS34 MRPS34 SPSB3 SPSB3 ENSUAMP00000017016 ENSUAMP00000017016 NRSN1 NRSN1 ENTPD3 ENTPD3 ENSUAMP00000018006 ENSUAMP00000018006 TTC5 TTC5 ENSUAMP00000018500 ENSUAMP00000018500 ENTPD8 ENTPD8 UPP1 UPP1 CALB2 CALB2 ENSUAMP00000019880 ENSUAMP00000019880 NME4 NME4 SVOPL SVOPL C16orf71 C16orf71 CLN8 CLN8 ENSUAMP00000020992 ENSUAMP00000020992 RIDA RIDA NT5C3A NT5C3A ENSUAMP00000022768 ENSUAMP00000022768 ENSUAMP00000022965 ENSUAMP00000022965 ENSUAMP00000023031 ENSUAMP00000023031 QTRT2 QTRT2 CC2D2A CC2D2A ENSUAMP00000024998 ENSUAMP00000024998 QTRT1 QTRT1 SLC12A1 SLC12A1 ENSUAMP00000025873 ENSUAMP00000025873 ENSUAMP00000025874 ENSUAMP00000025874 DHODH DHODH TK1 TK1 RRM2 RRM2 ENSUAMP00000028238 ENSUAMP00000028238 FBXL2 FBXL2 ENSUAMP00000028888 ENSUAMP00000028888 SVOP SVOP ENPP3 ENPP3 CENPW CENPW CTPS1 CTPS1 NME6 NME6 ENSUAMP00000031423 ENSUAMP00000031423 ENSUAMP00000031424 ENSUAMP00000031424 FBXO45 FBXO45 TLCD3B TLCD3B ENTPD7 ENTPD7 CMPK2 CMPK2 ENSUAMP00000032197 ENSUAMP00000032197 GOLT1A GOLT1A ENSUAMP00000032951 ENSUAMP00000032951 ENSUAMP00000033332 ENSUAMP00000033332 ENSUAMP00000033626 ENSUAMP00000033626 FBXL20 FBXL20 ENSUAMP00000034573 ENSUAMP00000034573 TMEM116 TMEM116 CEP97 CEP97 SPSB2 SPSB2 ENSUAMP00000035701 ENSUAMP00000035701 ENSUAMP00000035827 ENSUAMP00000035827 DCK DCK ENSUAMP00000036669 ENSUAMP00000036669 KDM1B KDM1B CMPK1 CMPK1 ENSUAMP00000037152 ENSUAMP00000037152 NT5C2 NT5C2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UCK2Uridine-cytidine kinase; Belongs to the uridine kinase family. (261 aa)
SLC25A42Solute carrier family 25 member 42; Belongs to the mitochondrial carrier (TC 2.A.29) family. (372 aa)
NT5C1A5'-nucleotidase, cytosolic IA. (366 aa)
UMPSOrotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. (302 aa)
UCKL1Uridine-cytidine kinase; Belongs to the uridine kinase family. (547 aa)
DUTDeoxyuridine triphosphatase. (175 aa)
UPRTUracil phosphoribosyltransferase homolog. (306 aa)
ENSUAMP00000002190Uncharacterized protein. (190 aa)
ENSUAMP00000002369Uncharacterized protein. (170 aa)
ENSUAMP00000002379DUF5523 domain-containing protein. (283 aa)
ENSUAMP00000002393Uncharacterized protein. (57 aa)
TYMSThymidylate synthetase. (342 aa)
GOLT1BGolgi transport 1B. (138 aa)
ENSUAMP00000004727Uncharacterized protein. (55 aa)
NME1Nucleoside diphosphate kinase. (152 aa)
NME2Nucleoside diphosphate kinase. (159 aa)
DCTPP1dCTP pyrophosphatase 1. (220 aa)
CANT1Calcium activated nucleotidase 1. (401 aa)
ENTPD5Ectonucleoside triphosphate diphosphohydrolase 5 (inactive); Belongs to the GDA1/CD39 NTPase family. (428 aa)
NUDT2Nudix hydrolase 2. (148 aa)
NT5M5',3'-nucleotidase, mitochondrial. (193 aa)
CDADC1Cytidine and dCMP deaminase domain containing 1. (499 aa)
ENSUAMP00000007133Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (283 aa)
ENSUAMP00000007917Uncharacterized protein. (62 aa)
TK2Thymidine kinase 2. (216 aa)
CADCarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2218 aa)
ENTPD4Ectonucleoside triphosphate diphosphohydrolase 4; Belongs to the GDA1/CD39 NTPase family. (463 aa)
TTLL1Tubulin tyrosine ligase like 1. (423 aa)
CTPS2CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (594 aa)
ENSUAMP00000009640Uncharacterized protein. (644 aa)
DTYMKDeoxythymidylate kinase. (261 aa)
HSPE1Uncharacterized protein; Belongs to the GroES chaperonin family. (95 aa)
UCK1Uridine-cytidine kinase; Belongs to the uridine kinase family. (276 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1. (863 aa)
TLCD3ATLC domain containing 3A. (222 aa)
NUDT11Nudix hydrolase 11. (168 aa)
ENSUAMP00000012079Uncharacterized protein. (306 aa)
TLCD4-RWDD3TLCD4-RWDD3 readthrough. (140 aa)
NT5C5', 3'-nucleotidase, cytosolic. (207 aa)
UPB1Beta-ureidopropionase 1. (384 aa)
NT5E5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (528 aa)
ENSUAMP00000014130Uncharacterized protein. (859 aa)
HDDC2HD domain containing 2. (233 aa)
CDACytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (146 aa)
ENSUAMP00000015279NDK domain-containing protein; Belongs to the NDK family. (181 aa)
ENSUAMP00000016204Uncharacterized protein. (185 aa)
SPSB4SplA/ryanodine receptor domain and SOCS box containing 4. (273 aa)
DCTDdCMP deaminase. (183 aa)
TTLL5Tubulin tyrosine ligase like 5. (1308 aa)
NME3Nucleoside diphosphate kinase. (169 aa)
MRPS34Mitochondrial ribosomal protein S34. (219 aa)
SPSB3SplA/ryanodine receptor domain and SOCS box containing 3. (379 aa)
ENSUAMP00000017016Uncharacterized protein. (181 aa)
NRSN1Neurensin 1. (196 aa)
ENTPD3Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family. (336 aa)
ENSUAMP00000018006Importin N-terminal domain-containing protein. (577 aa)
TTC5Tetratricopeptide repeat domain 5. (440 aa)
ENSUAMP00000018500Fer4_20 domain-containing protein. (166 aa)
ENTPD8Ectonucleoside triphosphate diphosphohydrolase 8; Belongs to the GDA1/CD39 NTPase family. (498 aa)
UPP1Uridine phosphorylase 1. (316 aa)
CALB2Calbindin 2. (276 aa)
ENSUAMP00000019880Uncharacterized protein. (141 aa)
NME4Nucleoside diphosphate kinase. (187 aa)
SVOPLSVOP like. (496 aa)
C16orf71Chromosome 16 open reading frame 71. (524 aa)
CLN8CLN8 transmembrane ER and ERGIC protein. (288 aa)
ENSUAMP00000020992ATP-cone domain-containing protein. (123 aa)
RIDAReactive intermediate imine deaminase A homolog. (137 aa)
NT5C3A5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (331 aa)
ENSUAMP00000022768Uncharacterized protein. (547 aa)
ENSUAMP00000022965Uncharacterized protein. (296 aa)
ENSUAMP00000023031Uncharacterized protein. (118 aa)
QTRT2Queuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine); Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily. (381 aa)
CC2D2ACoiled-coil and C2 domain containing 2A. (1034 aa)
ENSUAMP00000024998NDK domain-containing protein. (144 aa)
QTRT1Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...] (403 aa)
SLC12A1Solute carrier family 12 member 1. (973 aa)
ENSUAMP00000025873Uncharacterized protein. (534 aa)
ENSUAMP00000025874Uncharacterized protein. (404 aa)
DHODHDihydroorotate dehydrogenase (quinone). (434 aa)
TK1Thymidine kinase. (239 aa)
RRM2Ribonucleotide reductase regulatory subunit M2. (297 aa)
ENSUAMP00000028238PNP_UDP_1 domain-containing protein. (96 aa)
FBXL2F-box and leucine rich repeat protein 2. (422 aa)
ENSUAMP00000028888NDK domain-containing protein; Belongs to the NDK family. (89 aa)
SVOPSV2 related protein. (548 aa)
ENPP3Ectonucleotide pyrophosphatase/phosphodiesterase 3. (868 aa)
CENPWCentromere protein W. (88 aa)
CTPS1CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (636 aa)
NME6Nucleoside diphosphate kinase. (186 aa)
ENSUAMP00000031423Uncharacterized protein. (273 aa)
ENSUAMP00000031424B30.2/SPRY domain-containing protein. (268 aa)
FBXO45F-box protein 45. (303 aa)
TLCD3BTLC domain containing 3B. (275 aa)
ENTPD7Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family. (485 aa)
CMPK2Cytidine/uridine monophosphate kinase 2. (361 aa)
ENSUAMP000000321975'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (300 aa)
GOLT1AGolgi transport 1A. (152 aa)
ENSUAMP00000032951Uncharacterized protein. (506 aa)
ENSUAMP00000033332Nudix hydrolase domain-containing protein. (128 aa)
ENSUAMP00000033626OBG-type G domain-containing protein. (132 aa)
FBXL20F-box and leucine rich repeat protein 20. (436 aa)
ENSUAMP00000034573Uncharacterized protein. (370 aa)
TMEM116Transmembrane protein 116. (350 aa)
CEP97Centrosomal protein 97. (801 aa)
SPSB2SplA/ryanodine receptor domain and SOCS box containing 2. (263 aa)
ENSUAMP00000035701FHA domain-containing protein. (194 aa)
ENSUAMP00000035827Uncharacterized protein. (175 aa)
DCKDeoxycytidine kinase. (260 aa)
ENSUAMP00000036669Uncharacterized protein. (166 aa)
KDM1BLysine demethylase 1B. (769 aa)
CMPK1UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (228 aa)
ENSUAMP00000037152Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (178 aa)
NT5C25'-nucleotidase, cytosolic II. (569 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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