STRINGSTRING
ALDH5A1 ALDH5A1 ADSS2 ADSS2 ENSUAMP00000013191 ENSUAMP00000013191 ENSUAMP00000012486 ENSUAMP00000012486 TASP1 TASP1 GOT2 GOT2 ENSUAMP00000011289 ENSUAMP00000011289 ADSS1 ADSS1 RIMKLA RIMKLA NFU1 NFU1 TMEM116 TMEM116 ENSUAMP00000034573 ENSUAMP00000034573 ENSUAMP00000034435 ENSUAMP00000034435 ENSUAMP00000034433 ENSUAMP00000034433 ENSUAMP00000034431 ENSUAMP00000034431 ENSUAMP00000033138 ENSUAMP00000033138 ENSUAMP00000032873 ENSUAMP00000032873 CPS1 CPS1 GLUL GLUL GOT1 GOT1 GOT1L1 GOT1L1 ENSUAMP00000030469 ENSUAMP00000030469 AGXT2 AGXT2 GLS2 GLS2 ABAT ABAT AGXT AGXT GFPT1 GFPT1 GPKOW GPKOW ADSL ADSL CAD CAD GPT GPT ENSUAMP00000005697 ENSUAMP00000005697 GAD1 GAD1 SLC22A16 SLC22A16 ENSUAMP00000005308 ENSUAMP00000005308 ENSUAMP00000003825 ENSUAMP00000003825 IL4I1 IL4I1 LGSN LGSN ENSUAMP00000002190 ENSUAMP00000002190 ENSUAMP00000000911 ENSUAMP00000000911 ENSUAMP00000000256 ENSUAMP00000000256 ASRGL1 ASRGL1 ALDH4A1 ALDH4A1 PPAT PPAT ASPA ASPA GPT2 GPT2 NAALAD2 NAALAD2 RIMKLB RIMKLB ENSUAMP00000015562 ENSUAMP00000015562 NAALADL1 NAALADL1 ENSUAMP00000014831 ENSUAMP00000014831 ENSUAMP00000014177 ENSUAMP00000014177 ASNS ASNS TMEM109 TMEM109
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ALDH5A1Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (546 aa)
ADSS2Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (446 aa)
ENSUAMP00000013191CN hydrolase domain-containing protein. (91 aa)
ENSUAMP00000012486Uncharacterized protein. (314 aa)
TASP1Taspase 1. (394 aa)
GOT2Aspartate aminotransferase. (393 aa)
ENSUAMP00000011289Uncharacterized protein. (495 aa)
ADSS1Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (457 aa)
RIMKLARibosomal modification protein rimK like family member A. (391 aa)
NFU1NFU1 iron-sulfur cluster scaffold. (253 aa)
TMEM116Transmembrane protein 116. (350 aa)
ENSUAMP00000034573Uncharacterized protein. (370 aa)
ENSUAMP00000034435EF-hand_14 domain-containing protein. (259 aa)
ENSUAMP00000034433Uncharacterized protein. (103 aa)
ENSUAMP00000034431ANK_REP_REGION domain-containing protein. (93 aa)
ENSUAMP00000033138Uncharacterized protein. (153 aa)
ENSUAMP00000032873CN hydrolase domain-containing protein. (283 aa)
CPS1Carbamoyl-phosphate synthase 1. (994 aa)
GLULGlutamine synthetase. (484 aa)
GOT1Aspartate aminotransferase. (413 aa)
GOT1L1Glutamic-oxaloacetic transaminase 1 like 1. (406 aa)
ENSUAMP00000030469AAA domain-containing protein; Belongs to the AAA ATPase family. (303 aa)
AGXT2Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (513 aa)
GLS2Glutaminase 2. (602 aa)
ABAT4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (522 aa)
AGXTSerine--pyruvate aminotransferase. (414 aa)
GFPT1Glutamine--fructose-6-phosphate transaminase 1. (595 aa)
GPKOWG-patch domain and KOW motifs. (437 aa)
ADSLAdenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (493 aa)
CADCarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2218 aa)
GPTGlutamic--pyruvic transaminase. (622 aa)
ENSUAMP00000005697Uncharacterized protein. (93 aa)
GAD1Glutamate decarboxylase 1. (594 aa)
SLC22A16Solute carrier family 22 member 16. (576 aa)
ENSUAMP00000005308DAO domain-containing protein. (175 aa)
ENSUAMP00000003825N-acetyltransferase domain-containing protein. (134 aa)
IL4I1Interleukin 4 induced 1. (572 aa)
LGSNLengsin, lens protein with glutamine synthetase domain; Belongs to the glutamine synthetase family. (509 aa)
ENSUAMP00000002190Uncharacterized protein. (190 aa)
ENSUAMP00000000911Uncharacterized protein. (111 aa)
ENSUAMP00000000256Amine oxidase. (526 aa)
ASRGL1Asparaginase and isoaspartyl peptidase 1. (305 aa)
ALDH4A1Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (563 aa)
PPATAmidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (551 aa)
ASPAAspartoacylase. (313 aa)
GPT2Glutamic--pyruvic transaminase 2. (559 aa)
NAALAD2N-acetylated alpha-linked acidic dipeptidase 2. (817 aa)
RIMKLBRibosomal modification protein rimK like family member B. (386 aa)
ENSUAMP00000015562Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (471 aa)
NAALADL1N-acetylated alpha-linked acidic dipeptidase like 1. (733 aa)
ENSUAMP00000014831Uncharacterized protein. (351 aa)
ENSUAMP00000014177Glutamine amidotransferase type-2 domain-containing protein. (644 aa)
ASNSAsparagine synthetase [glutamine-hydrolyzing]. (561 aa)
TMEM109Transmembrane protein 109. (231 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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