STRINGSTRING
IREB2 IREB2 EZH1 EZH1 ACAT1 ACAT1 ENSUAMP00000009600 ENSUAMP00000009600 ENSUAMP00000009789 ENSUAMP00000009789 TTLL12 TTLL12 ALDH16A1 ALDH16A1 ENSUAMP00000010257 ENSUAMP00000010257 SETD1B SETD1B HADHA HADHA AMBN AMBN SMYD2 SMYD2 ALDH7A1 ALDH7A1 PRDM12 PRDM12 SETD5 SETD5 ENSUAMP00000012538 ENSUAMP00000012538 ENSUAMP00000012541 ENSUAMP00000012541 ENSUAMP00000012555 ENSUAMP00000012555 GCDH GCDH AADAT AADAT PLOD1 PLOD1 PRDM2 PRDM2 DLD DLD RAI1 RAI1 CENPC CENPC MGARP MGARP SNRNP35 SNRNP35 ENSUAMP00000016375 ENSUAMP00000016375 PHF20 PHF20 ENSUAMP00000017059 ENSUAMP00000017059 ENSUAMP00000017155 ENSUAMP00000017155 ENSUAMP00000017462 ENSUAMP00000017462 SELENOK SELENOK SETD1A SETD1A PHF23 PHF23 PIPOX PIPOX SMYD4 SMYD4 ENSUAMP00000019810 ENSUAMP00000019810 ENSUAMP00000020181 ENSUAMP00000020181 PLOD3 PLOD3 AASS AASS ECHS1 ECHS1 ENSUAMP00000020670 ENSUAMP00000020670 ENSUAMP00000020672 ENSUAMP00000020672 ERLIN1 ERLIN1 ENSUAMP00000036855 ENSUAMP00000036855 ENSUAMP00000036853 ENSUAMP00000036853 SCYL2 SCYL2 PRDM6 PRDM6 HADH HADH SMYD5 SMYD5 KMT2D KMT2D ENSUAMP00000035308 ENSUAMP00000035308 ENSUAMP00000035306 ENSUAMP00000035306 SETDB1 SETDB1 DOT1L DOT1L PHF6 PHF6 SETD2 SETD2 KIF9 KIF9 EHMT2 EHMT2 ENSUAMP00000031700 ENSUAMP00000031700 TCF20 TCF20 ERLIN2 ERLIN2 DHTKD1 DHTKD1 ENSUAMP00000030237 ENSUAMP00000030237 SETD7 SETD7 G2E3 G2E3 EZH2 EZH2 ENSUAMP00000028252 ENSUAMP00000028252 ALDH3A2 ALDH3A2 KMT2E KMT2E PLOD2 PLOD2 KMT2B KMT2B KMT2C KMT2C ASH1L ASH1L SETBP1 SETBP1 CERCAM CERCAM BBOX1 BBOX1 KMT5A KMT5A RNF126 RNF126 KMT5B KMT5B SMYD1 SMYD1 ENSUAMP00000023951 ENSUAMP00000023951 ENSUAMP00000023422 ENSUAMP00000023422 BCAS1 BCAS1 ENSUAMP00000021272 ENSUAMP00000021272 ENSUAMP00000023419 ENSUAMP00000023419 HYKK HYKK KMT5C KMT5C ENSUAMP00000021695 ENSUAMP00000021695 ENSUAMP00000007714 ENSUAMP00000007714 PHF7 PHF7 DNPH1 DNPH1 ZMYND15 ZMYND15 CARTPT CARTPT ALDH1B1 ALDH1B1 NSD3 NSD3 ENSUAMP00000005094 ENSUAMP00000005094 ENSUAMP00000004160 ENSUAMP00000004160 NSD2 NSD2 SUV39H2 SUV39H2 ENSUAMP00000001997 ENSUAMP00000001997 ENSUAMP00000001835 ENSUAMP00000001835 COLGALT1 COLGALT1 OGFOD2 OGFOD2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IREB2Iron responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family. (906 aa)
EZH1Enhancer of zeste 1 polycomb repressive complex 2 subunit. (747 aa)
ACAT1Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (417 aa)
ENSUAMP00000009600Uncharacterized protein. (157 aa)
ENSUAMP00000009789Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (3862 aa)
TTLL12Tubulin tyrosine ligase like 12. (650 aa)
ALDH16A1Aldehyde dehydrogenase family 16 member A1. (819 aa)
ENSUAMP00000010257MYND-type domain-containing protein. (181 aa)
SETD1BSET domain containing 1B, histone lysine methyltransferase. (1824 aa)
HADHAHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (812 aa)
AMBNAmeloblastin. (404 aa)
SMYD2SET and MYND domain containing 2. (439 aa)
ALDH7A1Aldehyde dehydrogenase 7 family member A1. (459 aa)
PRDM12PR domain zinc finger protein 12; Involved in the positive regulation of histone H3-K9 dimethylation; Belongs to the class V-like SAM-binding methyltransferase superfamily. (361 aa)
SETD5SET domain containing 5. (1458 aa)
ENSUAMP000000125382-oxoacid_dh domain-containing protein. (170 aa)
ENSUAMP00000012541Uncharacterized protein. (98 aa)
ENSUAMP00000012555Uncharacterized protein. (284 aa)
GCDHGlutaryl-CoA dehydrogenase. (436 aa)
AADATAminoadipate aminotransferase. (425 aa)
PLOD1Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1. (727 aa)
PRDM2PR/SET domain 2. (1707 aa)
DLDDihydrolipoyl dehydrogenase. (509 aa)
RAI1Retinoic acid induced 1. (1889 aa)
CENPCCentromere protein C. (929 aa)
MGARPMitochondria localized glutamic acid rich protein. (243 aa)
SNRNP35Small nuclear ribonucleoprotein U11/U12 subunit 35. (246 aa)
ENSUAMP00000016375Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (84 aa)
PHF20PHD finger protein 20. (1001 aa)
ENSUAMP000000170592-oxoacid_dh domain-containing protein. (248 aa)
ENSUAMP00000017155Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (518 aa)
ENSUAMP00000017462Uncharacterized protein. (88 aa)
SELENOKSelenoprotein K. (91 aa)
SETD1ASET domain containing 1A, histone lysine methyltransferase. (1044 aa)
PHF23PHD finger protein 23. (403 aa)
PIPOXPipecolic acid and sarcosine oxidase. (386 aa)
SMYD4SET and MYND domain containing 4. (796 aa)
ENSUAMP00000019810Uncharacterized protein. (884 aa)
ENSUAMP00000020181Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (171 aa)
PLOD3Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3. (792 aa)
AASSAminoadipate-semialdehyde synthase. (906 aa)
ECHS1Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family. (290 aa)
ENSUAMP00000020670Rab-GAP TBC domain-containing protein. (224 aa)
ENSUAMP00000020672Rab-GAP TBC domain-containing protein. (155 aa)
ERLIN1ER lipid raft associated 1. (348 aa)
ENSUAMP00000036855PWWP domain-containing protein. (570 aa)
ENSUAMP00000036853Uncharacterized protein. (1459 aa)
SCYL2SCY1 like pseudokinase 2. (745 aa)
PRDM6PR/SET domain 6. (589 aa)
HADHHydroxyacyl-CoA dehydrogenase. (374 aa)
SMYD5SMYD family member 5. (417 aa)
KMT2DLysine methyltransferase 2D. (5333 aa)
ENSUAMP00000035308Uncharacterized protein. (160 aa)
ENSUAMP00000035306Uncharacterized protein. (88 aa)
SETDB1SET domain bifurcated histone lysine methyltransferase 1. (1299 aa)
DOT1LHistone-lysine N-methyltransferase, H3 lysine-79 specific. (1520 aa)
PHF6PHD finger protein 6. (365 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2520 aa)
KIF9Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (827 aa)
EHMT2Euchromatic histone lysine methyltransferase 2. (1294 aa)
ENSUAMP00000031700Uncharacterized protein. (301 aa)
TCF20Transcription factor 20. (1890 aa)
ERLIN2ER lipid raft associated 2. (337 aa)
DHTKD1Dehydrogenase E1 and transketolase domain containing 1. (920 aa)
ENSUAMP00000030237Uncharacterized protein. (68 aa)
SETD7Histone-lysine N-methyltransferase SETD7; Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes. (366 aa)
G2E3G2/M-phase specific E3 ubiquitin protein ligase. (718 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (746 aa)
ENSUAMP00000028252Uncharacterized protein. (234 aa)
ALDH3A2Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (501 aa)
KMT2ELysine methyltransferase 2E. (1850 aa)
PLOD2Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2. (728 aa)
KMT2BLysine methyltransferase 2B. (2553 aa)
KMT2CLysine methyltransferase 2C. (4697 aa)
ASH1LASH1 like histone lysine methyltransferase. (2965 aa)
SETBP1SET binding protein 1. (1298 aa)
CERCAMCerebral endothelial cell adhesion molecule. (595 aa)
BBOX1Gamma-butyrobetaine hydroxylase 1. (387 aa)
KMT5ALysine methyltransferase 5A. (327 aa)
RNF126Ring finger protein 126. (313 aa)
KMT5BLysine methyltransferase 5B. (853 aa)
SMYD1SET and MYND domain containing 1. (489 aa)
ENSUAMP00000023951PWWP domain-containing protein. (538 aa)
ENSUAMP00000023422ANK_REP_REGION domain-containing protein. (975 aa)
BCAS1Breast carcinoma amplified sequence 1. (619 aa)
ENSUAMP00000021272Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (92 aa)
ENSUAMP00000023419SET domain-containing protein. (162 aa)
HYKKHydroxylysine kinase. (377 aa)
KMT5CLysine methyltransferase 5C. (467 aa)
ENSUAMP00000021695Uncharacterized protein. (260 aa)
ENSUAMP00000007714PHD domain-containing protein. (299 aa)
PHF7PHD finger protein 7. (361 aa)
DNPH12'-deoxynucleoside 5'-phosphate N-hydrolase 1. (103 aa)
ZMYND15Zinc finger MYND-type containing 15. (724 aa)
CARTPTCART prepropeptide. (128 aa)
ALDH1B1Aldehyde dehydrogenase 1 family member B1. (491 aa)
NSD3Nuclear receptor binding SET domain protein 3. (917 aa)
ENSUAMP00000005094Uncharacterized protein. (214 aa)
ENSUAMP00000004160Uncharacterized protein. (139 aa)
NSD2Nuclear receptor binding SET domain protein 2. (1344 aa)
SUV39H2Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (483 aa)
ENSUAMP00000001997Uncharacterized protein. (66 aa)
ENSUAMP00000001835Aldedh domain-containing protein. (222 aa)
COLGALT1Collagen beta(1-O)galactosyltransferase 1. (640 aa)
OGFOD22-oxoglutarate and iron dependent oxygenase domain containing 2. (373 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
Server load: low (22%) [HD]