STRINGSTRING
ODC1 ODC1 CNDP2 CNDP2 CNDP1 CNDP1 ALDH7A1 ALDH7A1 GOT2 GOT2 ALDH16A1 ALDH16A1 TTLL12 TTLL12 ENSUAMP00000009640 ENSUAMP00000009640 ENSUAMP00000008685 ENSUAMP00000008685 NUBP1 NUBP1 NOS2 NOS2 TINAG TINAG OAT OAT CARNS1 CARNS1 L3HYPDH L3HYPDH CRYM CRYM ALDH1B1 ALDH1B1 ENSUAMP00000005515 ENSUAMP00000005515 TINAGL1 TINAGL1 ENSUAMP00000005441 ENSUAMP00000005441 CCT8 CCT8 ENSUAMP00000004018 ENSUAMP00000004018 ENSUAMP00000003370 ENSUAMP00000003370 ENSUAMP00000003279 ENSUAMP00000003279 NOA1 NOA1 ENSUAMP00000001835 ENSUAMP00000001835 ENSUAMP00000001268 ENSUAMP00000001268 MAL2 MAL2 ANKRD1 ANKRD1 AZIN2 AZIN2 SRM SRM MYADM MYADM CLN8 CLN8 PYCR1 PYCR1 OGFOD1 OGFOD1 PLLP PLLP ENSUAMP00000022383 ENSUAMP00000022383 ENSUAMP00000022690 ENSUAMP00000022690 P4HTM P4HTM ENSUAMP00000024225 ENSUAMP00000024225 ENSUAMP00000024226 ENSUAMP00000024226 CMTM2 CMTM2 ENSUAMP00000024228 ENSUAMP00000024228 ENSUAMP00000024229 ENSUAMP00000024229 CKM CKM CCP110 CCP110 MAL MAL MALL MALL ALKBH6 ALKBH6 PRODH2 PRODH2 ENSUAMP00000026733 ENSUAMP00000026733 ALDH3A2 ALDH3A2 SAT1 SAT1 ALDH18A1 ALDH18A1 EIF2D EIF2D ARG1 ARG1 KDM1A KDM1A GOT1L1 GOT1L1 TLCD3B TLCD3B GOT1 GOT1 CMTM5 CMTM5 MYADML2 MYADML2 GATM GATM LAP3 LAP3 MED28 MED28 AZIN1 AZIN1 NOS3 NOS3 AOC1 AOC1 ENSUAMP00000033933 ENSUAMP00000033933 P4HA2 P4HA2 NOS1 NOS1 FBXO21 FBXO21 SMS SMS AMD1 AMD1 CCT8L2 CCT8L2 SMOX SMOX ALDH4A1 ALDH4A1 MAOB MAOB ENSUAMP00000036881 ENSUAMP00000036881 CMTM6 CMTM6 CKMT2 CKMT2 ENSUAMP00000037561 ENSUAMP00000037561 ENSUAMP00000018939 ENSUAMP00000018939 GAMT GAMT ENSUAMP00000018378 ENSUAMP00000018378 ENSUAMP00000018361 ENSUAMP00000018361 ENSUAMP00000017155 ENSUAMP00000017155 NUBP2 NUBP2 PYCR3 PYCR3 CKB CKB ENSUAMP00000014576 ENSUAMP00000014576 TMED8 TMED8 NOXRED1 NOXRED1 ENSUAMP00000014143 ENSUAMP00000014143 MAOA MAOA ENSUAMP00000013409 ENSUAMP00000013409 C10orf62 C10orf62 HOGA1 HOGA1 ANKRD2 ANKRD2 TLCD4-RWDD3 TLCD4-RWDD3 ARG2 ARG2 ENSUAMP00000019211 ENSUAMP00000019211 TLCD3A TLCD3A CMTM8 CMTM8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ODC1Ornithine decarboxylase 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (463 aa)
CNDP2Carnosine dipeptidase 2. (473 aa)
CNDP1Carnosine dipeptidase 1. (485 aa)
ALDH7A1Aldehyde dehydrogenase 7 family member A1. (459 aa)
GOT2Aspartate aminotransferase. (393 aa)
ALDH16A1Aldehyde dehydrogenase family 16 member A1. (819 aa)
TTLL12Tubulin tyrosine ligase like 12. (650 aa)
ENSUAMP00000009640Uncharacterized protein. (644 aa)
ENSUAMP00000008685DAO domain-containing protein. (116 aa)
NUBP1Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (320 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1064 aa)
TINAGTubulointerstitial nephritis antigen; Belongs to the peptidase C1 family. (476 aa)
OATOrnithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (399 aa)
CARNS1Carnosine synthase 1. (859 aa)
L3HYPDHTrans-L-3-hydroxyproline dehydratase. (357 aa)
CRYMCrystallin mu. (314 aa)
ALDH1B1Aldehyde dehydrogenase 1 family member B1. (491 aa)
ENSUAMP00000005515Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (445 aa)
TINAGL1Tubulointerstitial nephritis antigen like 1; Belongs to the peptidase C1 family. (467 aa)
ENSUAMP00000005441Uncharacterized protein. (80 aa)
CCT8Chaperonin containing TCP1 subunit 8. (502 aa)
ENSUAMP00000004018P4Ha_N domain-containing protein. (122 aa)
ENSUAMP00000003370MARVEL domain-containing protein. (170 aa)
ENSUAMP00000003279Fe2OG dioxygenase domain-containing protein. (282 aa)
NOA1Nitric oxide associated 1. (688 aa)
ENSUAMP00000001835Aldedh domain-containing protein. (222 aa)
ENSUAMP00000001268Uncharacterized protein. (244 aa)
MAL2MARVEL domain-containing protein. (176 aa)
ANKRD1Ankyrin repeat domain 1. (319 aa)
AZIN2Antizyme inhibitor 2; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (460 aa)
SRMSpermidine synthase; Belongs to the spermidine/spermine synthase family. (302 aa)
MYADMMyeloid associated differentiation marker. (322 aa)
CLN8CLN8 transmembrane ER and ERGIC protein. (288 aa)
PYCR1Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (320 aa)
OGFOD12-oxoglutarate and iron dependent oxygenase domain containing 1. (545 aa)
PLLPMARVEL domain-containing protein. (182 aa)
ENSUAMP00000022383N-acetyltransferase domain-containing protein. (96 aa)
ENSUAMP00000022690Uncharacterized protein. (94 aa)
P4HTMProlyl 4-hydroxylase, transmembrane. (497 aa)
ENSUAMP00000024225Uncharacterized protein. (95 aa)
ENSUAMP00000024226MARVEL domain-containing protein. (261 aa)
CMTM2CKLF like MARVEL transmembrane domain containing 2. (208 aa)
ENSUAMP00000024228MARVEL domain-containing protein. (96 aa)
ENSUAMP00000024229MARVEL domain-containing protein. (177 aa)
CKMCreatine kinase, M-type; Belongs to the ATP:guanido phosphotransferase family. (381 aa)
CCP110Centriolar coiled-coil protein 110. (998 aa)
MALMal, T cell differentiation protein. (144 aa)
MALLMal, T cell differentiation protein like. (145 aa)
ALKBH6AlkB homolog 6. (262 aa)
PRODH2Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (472 aa)
ENSUAMP00000026733ANK_REP_REGION domain-containing protein. (314 aa)
ALDH3A2Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (501 aa)
SAT1Spermidine/spermine N1-acetyltransferase 1. (173 aa)
ALDH18A1Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (795 aa)
EIF2DEukaryotic translation initiation factor 2D. (586 aa)
ARG1Arginase. (322 aa)
KDM1ALysine demethylase 1A. (734 aa)
GOT1L1Glutamic-oxaloacetic transaminase 1 like 1. (406 aa)
TLCD3BTLC domain containing 3B. (275 aa)
GOT1Aspartate aminotransferase. (413 aa)
CMTM5CKLF like MARVEL transmembrane domain containing 5. (156 aa)
MYADML2Myeloid associated differentiation marker like 2. (307 aa)
GATMGlycine amidinotransferase. (423 aa)
LAP3Leucine aminopeptidase 3. (568 aa)
MED28Mediator complex subunit 28. (170 aa)
AZIN1Antizyme inhibitor 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (448 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1202 aa)
AOC1Amine oxidase. (757 aa)
ENSUAMP00000033933Fe2OG dioxygenase domain-containing protein. (202 aa)
P4HA2Prolyl 4-hydroxylase subunit alpha 2. (393 aa)
NOS1Nitric oxide synthase; Produces nitric oxide (NO). (1095 aa)
FBXO21F-box protein 21. (456 aa)
SMSSpermine synthase. (383 aa)
AMD1S-adenosylmethionine decarboxylase proenzyme. (334 aa)
CCT8L2Chaperonin containing TCP1 subunit 8 like 2. (556 aa)
SMOXSpermine oxidase. (549 aa)
ALDH4A1Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (563 aa)
MAOBAmine oxidase. (529 aa)
ENSUAMP00000036881MARVEL domain-containing protein. (274 aa)
CMTM6CKLF like MARVEL transmembrane domain containing 6. (171 aa)
CKMT2Creatine kinase, mitochondrial 2; Belongs to the ATP:guanido phosphotransferase family. (419 aa)
ENSUAMP00000037561Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (374 aa)
ENSUAMP00000018939Uncharacterized protein; Belongs to the ATP:guanido phosphotransferase family. (417 aa)
GAMTGuanidinoacetate N-methyltransferase; Converts guanidinoacetate to creatine, using S- adenosylmethionine as the methyl donor. Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family. (236 aa)
ENSUAMP00000018378Amino_oxidase domain-containing protein. (141 aa)
ENSUAMP00000018361Uncharacterized protein. (168 aa)
ENSUAMP00000017155Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (518 aa)
NUBP2Nucleotide binding protein 2. (311 aa)
PYCR3Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (276 aa)
CKBCreatine kinase B; Belongs to the ATP:guanido phosphotransferase family. (381 aa)
ENSUAMP00000014576Fe2OG dioxygenase domain-containing protein. (244 aa)
TMED8Transmembrane p24 trafficking protein family member 8. (332 aa)
NOXRED1NADP dependent oxidoreductase domain containing 1. (329 aa)
ENSUAMP00000014143Uncharacterized protein. (157 aa)
MAOAAmine oxidase. (417 aa)
ENSUAMP00000013409Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (578 aa)
C10orf62Chromosome 10 open reading frame 62. (229 aa)
HOGA14-hydroxy-2-oxoglutarate aldolase 1; Belongs to the DapA family. (327 aa)
ANKRD2Ankyrin repeat domain 2. (335 aa)
TLCD4-RWDD3TLCD4-RWDD3 readthrough. (140 aa)
ARG2Arginase. (354 aa)
ENSUAMP00000019211MARVEL domain-containing protein. (136 aa)
TLCD3ATLC domain containing 3A. (222 aa)
CMTM8CKLF like MARVEL transmembrane domain containing 8. (100 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.