STRINGSTRING
MDH2 MDH2 MCEE MCEE ANKRD1 ANKRD1 ENSUAMP00000001149 ENSUAMP00000001149 ENSUAMP00000001521 ENSUAMP00000001521 LGSN LGSN WDTC1 WDTC1 ENSUAMP00000003008 ENSUAMP00000003008 NIPSNAP2 NIPSNAP2 ENSUAMP00000003272 ENSUAMP00000003272 HAO2 HAO2 SETD4 SETD4 GLDC GLDC PGP PGP ENSUAMP00000005324 ENSUAMP00000005324 ENSUAMP00000005537 ENSUAMP00000005537 CARTPT CARTPT ENSUAMP00000006155 ENSUAMP00000006155 ENSUAMP00000007578 ENSUAMP00000007578 ENSUAMP00000007641 ENSUAMP00000007641 ENSUAMP00000007782 ENSUAMP00000007782 ENSUAMP00000008430 ENSUAMP00000008430 AMT AMT ACAT1 ACAT1 SOGA1 SOGA1 CAT CAT ENSUAMP00000011098 ENSUAMP00000011098 ANKRD2 ANKRD2 HOGA1 HOGA1 C10orf62 C10orf62 DLD DLD SHMT1 SHMT1 ENSUAMP00000015522 ENSUAMP00000015522 GRHPR GRHPR MDH1 MDH1 URB2 URB2 ENSUAMP00000019038 ENSUAMP00000019038 ENSUAMP00000019553 ENSUAMP00000019553 ENSUAMP00000019554 ENSUAMP00000019554 NIPSNAP1 NIPSNAP1 ENSUAMP00000020181 ENSUAMP00000020181 SETD3 SETD3 ENSUAMP00000022865 ENSUAMP00000022865 MTCL1 MTCL1 AGXT AGXT PCCA PCCA PNPLA8 PNPLA8 ACO1 ACO1 MMUT MMUT SHMT2 SHMT2 AFMID AFMID ENSUAMP00000027388 ENSUAMP00000027388 ACO2 ACO2 ENSUAMP00000029554 ENSUAMP00000029554 ENSUAMP00000030469 ENSUAMP00000030469 ENSUAMP00000032411 ENSUAMP00000032411 KIAA0408 KIAA0408 GLUL GLUL ENSUAMP00000033767 ENSUAMP00000033767 ENSUAMP00000033916 ENSUAMP00000033916 PXDN PXDN CS CS HYI HYI ENSUAMP00000037554 ENSUAMP00000037554
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MDH2Malate dehydrogenase. (338 aa)
MCEEMethylmalonyl-CoA epimerase. (170 aa)
ANKRD1Ankyrin repeat domain 1. (319 aa)
ENSUAMP00000001149FMN hydroxy acid dehydrogenase domain-containing protein. (102 aa)
ENSUAMP00000001521Lipoyl-binding domain-containing protein. (129 aa)
LGSNLengsin, lens protein with glutamine synthetase domain; Belongs to the glutamine synthetase family. (509 aa)
WDTC1WD and tetratricopeptide repeats 1. (679 aa)
ENSUAMP00000003008Uncharacterized protein. (234 aa)
NIPSNAP2Nipsnap homolog 2. (286 aa)
ENSUAMP00000003272SHMT domain-containing protein. (59 aa)
HAO2Hydroxyacid oxidase 2. (383 aa)
SETD4SET domain containing 4. (355 aa)
GLDCGlycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (991 aa)
PGPPhosphoglycolate phosphatase; Belongs to the HAD-like hydrolase superfamily. (321 aa)
ENSUAMP00000005324FMN hydroxy acid dehydrogenase domain-containing protein. (188 aa)
ENSUAMP00000005537Uncharacterized protein. (246 aa)
CARTPTCART prepropeptide. (128 aa)
ENSUAMP00000006155DUF4147 domain-containing protein. (245 aa)
ENSUAMP00000007578ACAS_N domain-containing protein. (194 aa)
ENSUAMP00000007641Uncharacterized protein. (363 aa)
ENSUAMP00000007782Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (156 aa)
ENSUAMP00000008430Uncharacterized protein. (665 aa)
AMTAminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (403 aa)
ACAT1Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (417 aa)
SOGA1Suppressor of glucose, autophagy associated 1. (1264 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
ENSUAMP00000011098Uncharacterized protein. (257 aa)
ANKRD2Ankyrin repeat domain 2. (335 aa)
HOGA14-hydroxy-2-oxoglutarate aldolase 1; Belongs to the DapA family. (327 aa)
C10orf62Chromosome 10 open reading frame 62. (229 aa)
DLDDihydrolipoyl dehydrogenase. (509 aa)
SHMT1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (484 aa)
ENSUAMP00000015522Uncharacterized protein. (666 aa)
GRHPRGlyoxylate and hydroxypyruvate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (328 aa)
MDH1Malate dehydrogenase. (321 aa)
URB2URB2 ribosome biogenesis homolog. (1521 aa)
ENSUAMP00000019038CoA carboxyltransferase N-terminal domain-containing protein. (294 aa)
ENSUAMP00000019553Uncharacterized protein. (82 aa)
ENSUAMP00000019554Uncharacterized protein. (434 aa)
NIPSNAP1Nipsnap homolog 1. (301 aa)
ENSUAMP00000020181Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (171 aa)
SETD3Protein-histidine N-methyltransferase. (591 aa)
ENSUAMP00000022865ACAS_N domain-containing protein. (125 aa)
MTCL1Microtubule crosslinking factor 1. (1853 aa)
AGXTSerine--pyruvate aminotransferase. (414 aa)
PCCAPropionyl-CoA carboxylase subunit alpha. (573 aa)
PNPLA8Patatin like phospholipase domain containing 8. (780 aa)
ACO1Aconitase 1; Belongs to the aconitase/IPM isomerase family. (889 aa)
MMUTMethylmalonyl-CoA mutase. (750 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (504 aa)
AFMIDKynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. (285 aa)
ENSUAMP00000027388Uncharacterized protein. (60 aa)
ACO2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (799 aa)
ENSUAMP00000029554Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (159 aa)
ENSUAMP00000030469AAA domain-containing protein; Belongs to the AAA ATPase family. (303 aa)
ENSUAMP00000032411Uncharacterized protein. (945 aa)
KIAA0408KIAA0408. (692 aa)
GLULGlutamine synthetase. (484 aa)
ENSUAMP00000033767Uncharacterized protein. (60 aa)
ENSUAMP00000033916Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (328 aa)
PXDNPeroxidasin. (905 aa)
CSCitrate synthase; Belongs to the citrate synthase family. (466 aa)
HYIHydroxypyruvate isomerase (putative). (307 aa)
ENSUAMP00000037554Ig-like domain-containing protein. (361 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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