STRINGSTRING
NNT NNT NMRK1 NMRK1 ENSUAMP00000014130 ENSUAMP00000014130 ENSUAMP00000013944 ENSUAMP00000013944 NT5E NT5E SIRT2 SIRT2 NT5C NT5C ENSUAMP00000012079 ENSUAMP00000012079 ENPP1 ENPP1 TTLL1 TTLL1 NAMPT NAMPT NUDT12 NUDT12 ENSUAMP00000032951 ENSUAMP00000032951 NCAPD3 NCAPD3 NADK NADK ENPP3 ENPP3 SVOP SVOP ENSUAMP00000029041 ENSUAMP00000029041 ENSUAMP00000029039 ENSUAMP00000029039 NT5C1A NT5C1A ART4 ART4 KIF13A KIF13A NUDT13 NUDT13 NT5M NT5M NT5C2 NT5C2 QPRT QPRT ART5 ART5 ART1 ART1 KIF13B KIF13B ENSUAMP00000029038 ENSUAMP00000029038 ENSUAMP00000028238 ENSUAMP00000028238 MSANTD1 MSANTD1 ENSUAMP00000026000 ENSUAMP00000026000 NADSYN1 NADSYN1 NMNAT2 NMNAT2 SIRT4 SIRT4 SIRT6 SIRT6 ENSUAMP00000022768 ENSUAMP00000022768 NMNAT1 NMNAT1 NNMT NNMT SIRT7 SIRT7 SIRT1 SIRT1 SVOPL SVOPL AOX1 AOX1 CALB2 CALB2 SIRT5 SIRT5 ASPDH ASPDH SIRT3 SIRT3 ENSUAMP00000017016 ENSUAMP00000017016 TTLL5 TTLL5 BST1 BST1 ENSUAMP00000016204 ENSUAMP00000016204 MROH6 MROH6 NAPRT NAPRT
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NNTNicotinamide nucleotide transhydrogenase. (740 aa)
NMRK1Nicotinamide riboside kinase 1. (202 aa)
ENSUAMP00000014130Uncharacterized protein. (859 aa)
ENSUAMP00000013944Uncharacterized protein. (1357 aa)
NT5E5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (528 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (426 aa)
NT5C5', 3'-nucleotidase, cytosolic. (207 aa)
ENSUAMP00000012079Uncharacterized protein. (306 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1. (863 aa)
TTLL1Tubulin tyrosine ligase like 1. (423 aa)
NAMPTNicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (505 aa)
NUDT12Nudix hydrolase 12. (462 aa)
ENSUAMP00000032951Uncharacterized protein. (506 aa)
NCAPD3Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. (1491 aa)
NADKNAD kinase. (496 aa)
ENPP3Ectonucleotide pyrophosphatase/phosphodiesterase 3. (868 aa)
SVOPSV2 related protein. (548 aa)
ENSUAMP00000029041CTP_transf_like domain-containing protein. (61 aa)
ENSUAMP00000029039CTP_transf_like domain-containing protein. (180 aa)
NT5C1A5'-nucleotidase, cytosolic IA. (366 aa)
ART4NAD(P)(+)--arginine ADP-ribosyltransferase. (297 aa)
KIF13AKinesin family member 13A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1843 aa)
NUDT13Nudix hydrolase 13. (389 aa)
NT5M5',3'-nucleotidase, mitochondrial. (193 aa)
NT5C25'-nucleotidase, cytosolic II. (569 aa)
QPRTQuinolinate phosphoribosyltransferase. (324 aa)
ART5NAD(P)(+)--arginine ADP-ribosyltransferase. (283 aa)
ART1NAD(P)(+)--arginine ADP-ribosyltransferase. (315 aa)
KIF13BKinesin family member 13B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1838 aa)
ENSUAMP00000029038FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (92 aa)
ENSUAMP00000028238PNP_UDP_1 domain-containing protein. (96 aa)
MSANTD1Myb/SANT DNA binding domain containing 1. (274 aa)
ENSUAMP00000026000Uncharacterized protein. (224 aa)
NADSYN1Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. (723 aa)
NMNAT2Nicotinamide nucleotide adenylyltransferase 2. (307 aa)
SIRT4NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (312 aa)
SIRT6Sirtuin 6. (338 aa)
ENSUAMP00000022768Uncharacterized protein. (547 aa)
NMNAT1Nicotinamide-nucleotide adenylyltransferase. (280 aa)
NNMTNicotinamide N-methyltransferase. (264 aa)
SIRT7Sirtuin 7. (424 aa)
SIRT1Sirtuin 1. (618 aa)
SVOPLSVOP like. (496 aa)
AOX1Aldehyde oxidase 1. (1332 aa)
CALB2Calbindin 2. (276 aa)
SIRT5NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinyl [...] (324 aa)
ASPDHAspartate dehydrogenase domain containing. (284 aa)
SIRT3NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (374 aa)
ENSUAMP00000017016Uncharacterized protein. (181 aa)
TTLL5Tubulin tyrosine ligase like 5. (1308 aa)
BST1Bone marrow stromal cell antigen 1. (312 aa)
ENSUAMP00000016204Uncharacterized protein. (185 aa)
MROH6Maestro heat like repeat family member 6. (705 aa)
NAPRTNicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (538 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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