STRINGSTRING
TCP11L1 TCP11L1 HACD4 HACD4 ABHD17A ABHD17A ENSUAMP00000010243 ENSUAMP00000010243 ELOVL4 ELOVL4 ENSUAMP00000008074 ENSUAMP00000008074 ENSUAMP00000008071 ENSUAMP00000008071 ENSUAMP00000008069 ENSUAMP00000008069 ENSUAMP00000008067 ENSUAMP00000008067 ENSUAMP00000007907 ENSUAMP00000007907 BSN BSN ELOVL7 ELOVL7 HSDL2 HSDL2 HSDL1 HSDL1 ENSUAMP00000006085 ENSUAMP00000006085 ACAA1 ACAA1 ACOT7 ACOT7 ZNF277 ZNF277 ACOX1 ACOX1 TCP11L2 TCP11L2 ABHD13 ABHD13 SCP2D1 SCP2D1 ENSUAMP00000002265 ENSUAMP00000002265 FADS3 FADS3 ENSUAMP00000002211 ENSUAMP00000002211 ENSUAMP00000001793 ENSUAMP00000001793 ELOVL6 ELOVL6 ENSUAMP00000001063 ENSUAMP00000001063 ELOVL1 ELOVL1 ENSUAMP00000000227 ENSUAMP00000000227 HSD17B12 HSD17B12 ELOVL3 ELOVL3 DEPDC7 DEPDC7 SLTM SLTM TCP11 TCP11 ABHD17C ABHD17C ENSUAMP00000031601 ENSUAMP00000031601 TECRL TECRL ABHD17B ABHD17B CEMIP2 CEMIP2 ENSUAMP00000027111 ENSUAMP00000027111 BAAT BAAT HACD3 HACD3 ELOVL5 ELOVL5 ENSUAMP00000024580 ENSUAMP00000024580 ENSUAMP00000024577 ENSUAMP00000024577 ENSUAMP00000024543 ENSUAMP00000024543 FADS1 FADS1 SCD SCD TECR TECR ELOVL2 ELOVL2 ENSUAMP00000020850 ENSUAMP00000020850 SCP2 SCP2 ENSUAMP00000017426 ENSUAMP00000017426 ENSUAMP00000016299 ENSUAMP00000016299 ENSUAMP00000015938 ENSUAMP00000015938 ACOX3 ACOX3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TCP11L1T-complex 11 like 1. (411 aa)
HACD4Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (229 aa)
ABHD17AAbhydrolase domain containing 17A. (310 aa)
ENSUAMP00000010243Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (318 aa)
ELOVL4Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (314 aa)
ENSUAMP00000008074Uncharacterized protein. (452 aa)
ENSUAMP00000008071BAAT_C domain-containing protein. (207 aa)
ENSUAMP00000008069Uncharacterized protein. (420 aa)
ENSUAMP00000008067BAAT_C domain-containing protein. (197 aa)
ENSUAMP00000007907SAP domain-containing protein. (61 aa)
BSNBassoon presynaptic cytomatrix protein. (3832 aa)
ELOVL7Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...] (281 aa)
HSDL2Hydroxysteroid dehydrogenase like 2. (390 aa)
HSDL1Hydroxysteroid dehydrogenase like 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (306 aa)
ENSUAMP00000006085Uncharacterized protein. (64 aa)
ACAA1Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (414 aa)
ACOT7Acyl-CoA thioesterase 7. (357 aa)
ZNF277Zinc finger protein 277. (409 aa)
ACOX1Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (655 aa)
TCP11L2T-complex 11 like 2. (459 aa)
ABHD13Abhydrolase domain containing 13. (337 aa)
SCP2D1SCP2 sterol binding domain containing 1. (156 aa)
ENSUAMP00000002265Uncharacterized protein. (503 aa)
FADS3Fatty acid desaturase 3. (443 aa)
ENSUAMP00000002211FA_desaturase domain-containing protein. (243 aa)
ENSUAMP00000001793HotDog ACOT-type domain-containing protein. (187 aa)
ELOVL6Elongation of very long chain fatty acids protein. (181 aa)
ENSUAMP00000001063Elongation of very long chain fatty acids protein. (96 aa)
ELOVL1Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (291 aa)
ENSUAMP00000000227Uncharacterized protein. (123 aa)
HSD17B12Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (227 aa)
ELOVL3Elongation of very long chain fatty acids protein 3; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precurs [...] (270 aa)
DEPDC7DEP domain containing 7. (322 aa)
SLTMSAFB like transcription modulator. (975 aa)
TCP11T-complex 11. (519 aa)
ABHD17CAbhydrolase domain containing 17C. (207 aa)
ENSUAMP00000031601Uncharacterized protein. (145 aa)
TECRLTrans-2,3-enoyl-CoA reductase like. (341 aa)
ABHD17BAbhydrolase domain containing 17B. (288 aa)
CEMIP2Cell migration inducing hyaluronidase 2. (1378 aa)
ENSUAMP00000027111Uncharacterized protein. (418 aa)
BAATBile acid-CoA:amino acid N-acyltransferase. (421 aa)
HACD3Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (337 aa)
ELOVL5Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] (299 aa)
ENSUAMP00000024580Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (241 aa)
ENSUAMP00000024577Uncharacterized protein. (146 aa)
ENSUAMP00000024543Uncharacterized protein. (554 aa)
FADS1Fatty acid desaturase 1. (466 aa)
SCDStearoyl-CoA desaturase; Belongs to the fatty acid desaturase type 1 family. (359 aa)
TECRTrans-2,3-enoyl-CoA reductase. (410 aa)
ELOVL2Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production [...] (279 aa)
ENSUAMP00000020850Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (176 aa)
SCP2Sterol carrier protein 2. (457 aa)
ENSUAMP00000017426Cytochrome b5 heme-binding domain-containing protein. (478 aa)
ENSUAMP00000016299Uncharacterized protein. (200 aa)
ENSUAMP00000015938Uncharacterized protein; Belongs to the fatty acid desaturase type 1 family. (134 aa)
ACOX3Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (700 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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