STRINGSTRING
MAPK12 MAPK12 ENSUAMP00000003880 ENSUAMP00000003880 ENSUAMP00000004316 ENSUAMP00000004316 LPAR1 LPAR1 PLCB2 PLCB2 FGF9 FGF9 PDGFB PDGFB FLT4 FLT4 ADCY9 ADCY9 ENSUAMP00000005976 ENSUAMP00000005976 ENSUAMP00000006744 ENSUAMP00000006744 FGF23 FGF23 FGF6 FGF6 ITGA2B ITGA2B SIPA1L2 SIPA1L2 PRKCB PRKCB GNAI3 GNAI3 FGF5 FGF5 FGF10 FGF10 CRKL CRKL FGF20 FGF20 ADCY2 ADCY2 CALML5 CALML5 RHOB RHOB ADCY3 ADCY3 RRAS RRAS LPAR3 LPAR3 PDGFA PDGFA PIK3CA PIK3CA VAV2 VAV2 MET MET EFNA5 EFNA5 PRKD1 PRKD1 ITGB1 ITGB1 GNAO1 GNAO1 PLCG1 PLCG1 MRAS MRAS FARP2 FARP2 ENSUAMP00000010308 ENSUAMP00000010308 ITGAM ITGAM PIK3R1 PIK3R1 PRKCA PRKCA AKT1 AKT1 PLCB1 PLCB1 RAP1B RAP1B ENSUAMP00000010738 ENSUAMP00000010738 FGFR3 FGFR3 ENSUAMP00000010836 ENSUAMP00000010836 ENSUAMP00000011260 ENSUAMP00000011260 AKT3 AKT3 PLCE1 PLCE1 RAPGEF1 RAPGEF1 ENSUAMP00000011922 ENSUAMP00000011922 ENSUAMP00000011933 ENSUAMP00000011933 ENSUAMP00000012405 ENSUAMP00000012405 ENSUAMP00000012593 ENSUAMP00000012593 RALB RALB FGF21 FGF21 RASGRP2 RASGRP2 ADORA2A ADORA2A MAPK1 MAPK1 ERAS ERAS CALML6 CALML6 VEGFC VEGFC F2RL3 F2RL3 ENSUAMP00000014588 ENSUAMP00000014588 ENSUAMP00000014590 ENSUAMP00000014590 ENSUAMP00000014629 ENSUAMP00000014629 ENSUAMP00000014720 ENSUAMP00000014720 TRBV16 TRBV16 IGF1R IGF1R FGF7 FGF7 ENSUAMP00000015497 ENSUAMP00000015497 ENSUAMP00000015637 ENSUAMP00000015637 ENSUAMP00000015817 ENSUAMP00000015817 ENSUAMP00000015819 ENSUAMP00000015819 TRBV28 TRBV28 ENSUAMP00000015993 ENSUAMP00000015993 ENSUAMP00000016017 ENSUAMP00000016017 ENSUAMP00000016042 ENSUAMP00000016042 ENSUAMP00000016192 ENSUAMP00000016192 CRK CRK PDGFD PDGFD PGF PGF RPS6KL1 RPS6KL1 CTNNB1 CTNNB1 MAPK11 MAPK11 ENSUAMP00000017364 ENSUAMP00000017364 ENSUAMP00000017435 ENSUAMP00000017435 TEK TEK SIPA1L3 SIPA1L3 ENSUAMP00000017692 ENSUAMP00000017692 GALK2 GALK2 ENSUAMP00000017872 ENSUAMP00000017872 RAP1A RAP1A ADAM15 ADAM15 EPHA2 EPHA2 KIT KIT PDGFRA PDGFRA PRKCI PRKCI PRKD3 PRKD3 PLCB3 PLCB3 VEGFB VEGFB ENSUAMP00000019309 ENSUAMP00000019309 PIK3CD PIK3CD CALML4 CALML4 ENSUAMP00000019485 ENSUAMP00000019485 ENSUAMP00000019945 ENSUAMP00000019945 VEGFA VEGFA F2R F2R PARD6A PARD6A PRKCG PRKCG MAP2K3 MAP2K3 KRAS KRAS GNAQ GNAQ ENSUAMP00000020826 ENSUAMP00000020826 IGF1 IGF1 ACTG1 ACTG1 CALM3 CALM3 PRKD2 PRKD2 GRIN2A GRIN2A THBS1 THBS1 ENSUAMP00000022131 ENSUAMP00000022131 ENSUAMP00000022172 ENSUAMP00000022172 BCAR1 BCAR1 FGFR2 FGFR2 INSR INSR P2RY1 P2RY1 AFDN AFDN ANGPT2 ANGPT2 DRD2 DRD2 ENSUAMP00000023048 ENSUAMP00000023048 KDR KDR NGFR NGFR ENSUAMP00000023691 ENSUAMP00000023691 ENSUAMP00000023925 ENSUAMP00000023925 ENSUAMP00000024427 ENSUAMP00000024427 ENSUAMP00000024618 ENSUAMP00000024618 BRAF BRAF LPAR4 LPAR4 FGF22 FGF22 ADORA2B ADORA2B ENSUAMP00000025300 ENSUAMP00000025300 ENSUAMP00000025311 ENSUAMP00000025311 FGFR1 FGFR1 ENSUAMP00000025726 ENSUAMP00000025726 VASP VASP ENSUAMP00000026030 ENSUAMP00000026030 ENSUAMP00000026156 ENSUAMP00000026156 CDC42 CDC42 ENSUAMP00000026421 ENSUAMP00000026421 ENAH ENAH EFNA1 EFNA1 ENSUAMP00000026789 ENSUAMP00000026789 SIPA1 SIPA1 MAP2K6 MAP2K6 ENSUAMP00000026981 ENSUAMP00000026981 ENSUAMP00000026993 ENSUAMP00000026993 INS INS PARD6B PARD6B MAGI3 MAGI3 GRIN1 GRIN1 ADCY5 ADCY5 ADCY1 ADCY1 ENSUAMP00000028152 ENSUAMP00000028152 ENSUAMP00000028178 ENSUAMP00000028178 ENSUAMP00000028179 ENSUAMP00000028179 GNAS GNAS ENSUAMP00000028558 ENSUAMP00000028558 ANGPT4 ANGPT4 ITGAL ITGAL PLCB4 PLCB4 CSF1 CSF1 ENSUAMP00000029031 ENSUAMP00000029031 ENSUAMP00000029280 ENSUAMP00000029280 ENSUAMP00000029322 ENSUAMP00000029322 ENSUAMP00000029400 ENSUAMP00000029400 RASSF5 RASSF5 LPAR5 LPAR5 RAP1GAP RAP1GAP FGF1 FGF1 KITLG KITLG SRC SRC ENSUAMP00000030280 ENSUAMP00000030280 FLT1 FLT1 MAP2K1 MAP2K1 RASGRP3 RASGRP3 ID1 ID1 RAC1 RAC1 VEGFD VEGFD PFN3 PFN3 RGS14 RGS14 FGF18 FGF18 ENSUAMP00000030750 ENSUAMP00000030750 RAF1 RAF1 ENSUAMP00000030787 ENSUAMP00000030787 ENSUAMP00000030878 ENSUAMP00000030878 FYB1 FYB1 RAPGEF5 RAPGEF5 RALA RALA SIPA1L1 SIPA1L1 RAC2 RAC2 ENSUAMP00000031486 ENSUAMP00000031486 VAV1 VAV1 MAPK3 MAPK3 NGF NGF ENSUAMP00000031589 ENSUAMP00000031589 RAPGEF4 RAPGEF4 ENSUAMP00000031719 ENSUAMP00000031719 ADCY4 ADCY4 RAC3 RAC3 ENSUAMP00000032150 ENSUAMP00000032150 CSF1R CSF1R PDGFRB PDGFRB MAPK14 MAPK14 MAPK13 MAPK13 ADCY7 ADCY7 FGF19 FGF19 FGF4 FGF4 FGF3 FGF3 ENSUAMP00000032618 ENSUAMP00000032618 ENSUAMP00000032909 ENSUAMP00000032909 DOCK4 DOCK4 CTNND1 CTNND1 PFN4 PFN4 PDGFC PDGFC TLNRD1 TLNRD1 ENSUAMP00000033583 ENSUAMP00000033583 ENSUAMP00000033929 ENSUAMP00000033929 GRIN2B GRIN2B CDH1 CDH1 ITGB2 ITGB2 ENSUAMP00000035331 ENSUAMP00000035331 TLN1 TLN1 ENSUAMP00000035608 ENSUAMP00000035608 ENSUAMP00000035622 ENSUAMP00000035622 CALM2 CALM2 ADCY6 ADCY6 ENSUAMP00000036162 ENSUAMP00000036162 ENSUAMP00000036253 ENSUAMP00000036253 RAPGEF2 RAPGEF2 ENSUAMP00000036324 ENSUAMP00000036324 FGFR4 FGFR4 LCP2 LCP2 GNAI2 GNAI2 ARAP3 ARAP3 ENSUAMP00000037462 ENSUAMP00000037462 AKT2 AKT2 ENSUAMP00000003693 ENSUAMP00000003693 PFN1 PFN1 ENSUAMP00000003263 ENSUAMP00000003263 ENSUAMP00000003162 ENSUAMP00000003162 FGF17 FGF17 ENSUAMP00000002874 ENSUAMP00000002874 ANGPT1 ANGPT1 EGF EGF PFN2 PFN2 ENSUAMP00000001068 ENSUAMP00000001068 LPAR2 LPAR2 FGF16 FGF16 APBB1IP APBB1IP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAPK12Mitogen-activated protein kinase 12. (373 aa)
ENSUAMP00000003880Uncharacterized protein. (91 aa)
ENSUAMP00000004316Ephrin RBD domain-containing protein; Belongs to the ephrin family. (216 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (271 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1166 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1363 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1338 aa)
ENSUAMP00000005976Uncharacterized protein. (94 aa)
ENSUAMP00000006744Uncharacterized protein. (509 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (245 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1032 aa)
SIPA1L2Signal induced proliferation associated 1 like 2. (1718 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (651 aa)
GNAI3G protein subunit alpha i3. (295 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (270 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1112 aa)
CALML5Calmodulin like 5. (156 aa)
RHOBRas homolog family member B. (172 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (973 aa)
RRASRAS related. (218 aa)
LPAR3Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family. (354 aa)
PDGFAPlatelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (248 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
VAV2Vav guanine nucleotide exchange factor 2. (855 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1399 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (188 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (848 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (771 aa)
GNAO1G protein subunit alpha o1. (354 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1256 aa)
MRASMuscle RAS oncogene homolog. (208 aa)
FARP2FERM, ARH/RhoGEF and pleckstrin domain protein 2. (1052 aa)
ENSUAMP00000010308Uncharacterized protein. (854 aa)
ITGAMIntegrin subunit alpha M; Belongs to the integrin alpha chain family. (1208 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (676 aa)
PRKCAProtein kinase C alpha; Belongs to the protein kinase superfamily. (484 aa)
AKT1Non-specific serine/threonine protein kinase. (572 aa)
PLCB1Phosphoinositide phospholipase C. (658 aa)
RAP1BRAP1B, member of RAS oncogene family. (184 aa)
ENSUAMP00000010738Uncharacterized protein. (181 aa)
FGFR3Fibroblast growth factor receptor. (691 aa)
ENSUAMP00000010836Uncharacterized protein. (951 aa)
ENSUAMP00000011260DUF1968 domain-containing protein. (153 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PLCE1Phosphoinositide phospholipase C. (1942 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1234 aa)
ENSUAMP00000011922VASP_tetra domain-containing protein. (53 aa)
ENSUAMP00000011933WH1 domain-containing protein. (160 aa)
ENSUAMP00000012405Uncharacterized protein. (110 aa)
ENSUAMP00000012593PH domain-containing protein. (647 aa)
RALBRAS like proto-oncogene B. (206 aa)
FGF21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
RASGRP2RAS guanyl releasing protein 2. (608 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (409 aa)
MAPK1Mitogen-activated protein kinase. (364 aa)
ERASES cell expressed Ras. (219 aa)
CALML6Calmodulin like 6. (180 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (391 aa)
F2RL3F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. (381 aa)
ENSUAMP00000014588IGv domain-containing protein. (107 aa)
ENSUAMP00000014590Ig-like domain-containing protein. (148 aa)
ENSUAMP00000014629Uncharacterized protein. (105 aa)
ENSUAMP00000014720Ig-like domain-containing protein. (177 aa)
TRBV16T cell receptor beta variable 16 (gene/pseudogene). (127 aa)
IGF1RTyrosine-protein kinase receptor. (1288 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
ENSUAMP00000015497Profilin; Belongs to the profilin family. (135 aa)
ENSUAMP00000015637I/LWEQ domain-containing protein. (735 aa)
ENSUAMP00000015817Ig-like domain-containing protein. (126 aa)
ENSUAMP00000015819Ig-like domain-containing protein. (141 aa)
TRBV28T cell receptor beta variable 28. (113 aa)
ENSUAMP00000015993Uncharacterized protein. (98 aa)
ENSUAMP00000016017PDZ domain-containing protein. (394 aa)
ENSUAMP00000016042Ig-like domain-containing protein. (387 aa)
ENSUAMP00000016192Integrin beta; Belongs to the integrin beta chain family. (786 aa)
CRKCRK proto-oncogene, adaptor protein. (204 aa)
PDGFDPlatelet derived growth factor D. (368 aa)
PGFPlacental growth factor; Belongs to the PDGF/VEGF growth factor family. (170 aa)
RPS6KL1Ribosomal protein S6 kinase like 1. (488 aa)
CTNNB1Catenin beta 1. (781 aa)
MAPK11Mitogen-activated protein kinase. (357 aa)
ENSUAMP00000017364Uncharacterized protein. (53 aa)
ENSUAMP00000017435Uncharacterized protein. (459 aa)
TEKTEK receptor tyrosine kinase. (1125 aa)
SIPA1L3Signal induced proliferation associated 1 like 3. (1774 aa)
ENSUAMP00000017692Uncharacterized protein. (704 aa)
GALK2Galactokinase 2. (460 aa)
ENSUAMP00000017872DH domain-containing protein. (687 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
ADAM15ADAM metallopeptidase domain 15. (832 aa)
EPHA2EPH receptor A2. (966 aa)
KITKIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (999 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (587 aa)
PRKD3Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (876 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1172 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (191 aa)
ENSUAMP00000019309Calponin-homology (CH) domain-containing protein. (82 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1041 aa)
CALML4Calmodulin like 4. (153 aa)
ENSUAMP00000019485Rap-GAP domain-containing protein. (427 aa)
ENSUAMP00000019945Uncharacterized protein. (237 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (516 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (427 aa)
PARD6APar-6 family cell polarity regulator alpha. (348 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (714 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
KRASKRAS proto-oncogene, GTPase. (188 aa)
GNAQG protein subunit alpha q. (352 aa)
ENSUAMP00000020826Ig-like domain-containing protein. (196 aa)
IGF1Insulin like growth factor 1. (171 aa)
ACTG1Actin gamma 1. (375 aa)
CALM3Calmodulin 3; Belongs to the calmodulin family. (149 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (840 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1427 aa)
THBS1Thrombospondin 1. (1170 aa)
ENSUAMP00000022131Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (636 aa)
ENSUAMP00000022172Uncharacterized protein. (157 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (867 aa)
FGFR2Fibroblast growth factor receptor 2. (661 aa)
INSRTyrosine-protein kinase receptor. (1072 aa)
P2RY1Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (374 aa)
AFDNAfadin, adherens junction formation factor. (1540 aa)
ANGPT2Angiopoietin 2. (494 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
ENSUAMP00000023048PB1 domain-containing protein. (123 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1282 aa)
NGFRNerve growth factor receptor. (388 aa)
ENSUAMP00000023691Uncharacterized protein. (268 aa)
ENSUAMP00000023925Ig-like domain-containing protein. (180 aa)
ENSUAMP00000024427Recep_L_domain domain-containing protein. (297 aa)
ENSUAMP00000024618Uncharacterized protein. (67 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (728 aa)
LPAR4Lysophosphatidic acid receptor 4; Belongs to the G-protein coupled receptor 1 family. (370 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (171 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (221 aa)
ENSUAMP00000025300Non-specific serine/threonine protein kinase. (254 aa)
ENSUAMP00000025311Uncharacterized protein. (295 aa)
FGFR1Fibroblast growth factor receptor. (848 aa)
ENSUAMP00000025726annotation not available (113 aa)
VASPVasodilator stimulated phosphoprotein. (359 aa)
ENSUAMP00000026030Uncharacterized protein. (236 aa)
ENSUAMP00000026156Uncharacterized protein. (692 aa)
CDC42Cell division cycle 42. (191 aa)
ENSUAMP00000026421Uncharacterized protein. (776 aa)
ENAHENAH actin regulator. (761 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (205 aa)
ENSUAMP00000026789Ephrin RBD domain-containing protein; Belongs to the ephrin family. (221 aa)
SIPA1Signal-induced proliferation-associated 1. (1024 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
ENSUAMP00000026981Uncharacterized protein. (580 aa)
ENSUAMP00000026993Uncharacterized protein. (118 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (106 aa)
PARD6BPar-6 family cell polarity regulator beta. (370 aa)
MAGI3Membrane associated guanylate kinase, WW and PDZ domain containing 3. (1299 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (814 aa)
ADCY5Adenylate cyclase 5. (940 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1119 aa)
ENSUAMP00000028152SH3 domain-containing protein. (120 aa)
ENSUAMP00000028178Uncharacterized protein. (311 aa)
ENSUAMP00000028179CSD domain-containing protein. (89 aa)
GNASGNAS complex locus. (994 aa)
ENSUAMP00000028558Uncharacterized protein. (222 aa)
ANGPT4Angiopoietin 4. (446 aa)
ITGALIntegrin subunit alpha L; Belongs to the integrin alpha chain family. (1014 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1136 aa)
CSF1Colony stimulating factor 1. (518 aa)
ENSUAMP00000029031Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa)
ENSUAMP00000029280DUF1968 domain-containing protein. (198 aa)
ENSUAMP00000029322Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (102 aa)
ENSUAMP00000029400Uncharacterized protein. (499 aa)
RASSF5Ras association domain family member 5. (416 aa)
LPAR5Lysophosphatidic acid receptor 5; Belongs to the G-protein coupled receptor 1 family. (368 aa)
RAP1GAPRAP1 GTPase activating protein. (802 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (274 aa)
SRCTyrosine-protein kinase. (557 aa)
ENSUAMP00000030280Protein kinase domain-containing protein. (206 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1265 aa)
MAP2K1Protein kinase domain-containing protein. (216 aa)
RASGRP3RAS guanyl releasing protein 3. (663 aa)
ID1Inhibitor of DNA binding 1, HLH protein. (154 aa)
RAC1Rac family small GTPase 1. (229 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (329 aa)
PFN3Profilin; Belongs to the profilin family. (137 aa)
RGS14Regulator of G protein signaling 14. (568 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (203 aa)
ENSUAMP00000030750Uncharacterized protein. (160 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (564 aa)
ENSUAMP00000030787Uncharacterized protein. (84 aa)
ENSUAMP00000030878Profilin; Belongs to the profilin family. (147 aa)
FYB1FYN binding protein 1. (765 aa)
RAPGEF5Rap guanine nucleotide exchange factor 5. (760 aa)
RALARAS like proto-oncogene A. (206 aa)
SIPA1L1Signal induced proliferation associated 1 like 1. (1327 aa)
RAC2Rac family small GTPase 2. (192 aa)
ENSUAMP00000031486Calponin-homology (CH) domain-containing protein. (86 aa)
VAV1Vav guanine nucleotide exchange factor 1. (774 aa)
MAPK3Mitogen-activated protein kinase. (354 aa)
NGFNerve growth factor; Belongs to the NGF-beta family. (240 aa)
ENSUAMP00000031589Uncharacterized protein. (1575 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4. (1019 aa)
ENSUAMP00000031719Uncharacterized protein. (627 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
RAC3Rac family small GTPase 3. (202 aa)
ENSUAMP00000032150PB1 domain-containing protein. (125 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (967 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1100 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1078 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (215 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (197 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (226 aa)
ENSUAMP00000032618Uncharacterized protein. (68 aa)
ENSUAMP00000032909Uncharacterized protein. (592 aa)
DOCK4Dedicator of cytokinesis 4; Belongs to the DOCK family. (1431 aa)
CTNND1Catenin delta 1. (961 aa)
PFN4Profilin; Belongs to the profilin family. (129 aa)
PDGFCPlatelet derived growth factor C. (218 aa)
TLNRD1Talin rod domain containing 1. (362 aa)
ENSUAMP00000033583Uncharacterized protein. (659 aa)
ENSUAMP00000033929PB1 domain-containing protein. (137 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (881 aa)
ITGB2Integrin beta. (815 aa)
ENSUAMP00000035331Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (506 aa)
TLN1Talin 1. (2550 aa)
ENSUAMP00000035608Uncharacterized protein. (85 aa)
ENSUAMP00000035622Uncharacterized protein. (662 aa)
CALM2Calmodulin 2; Belongs to the calmodulin family. (163 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1164 aa)
ENSUAMP00000036162Protein kinase domain-containing protein. (462 aa)
ENSUAMP00000036253Protein kinase domain-containing protein. (66 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1516 aa)
ENSUAMP00000036324Uncharacterized protein. (189 aa)
FGFR4Fibroblast growth factor receptor. (836 aa)
LCP2Lymphocyte cytosolic protein 2. (511 aa)
GNAI2G protein subunit alpha i2. (436 aa)
ARAP3ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3. (1537 aa)
ENSUAMP00000037462FERM domain-containing protein. (305 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
ENSUAMP00000003693Uncharacterized protein. (166 aa)
PFN1Profilin; Belongs to the profilin family. (164 aa)
ENSUAMP00000003263Ig-like domain-containing protein. (160 aa)
ENSUAMP00000003162Ig-like domain-containing protein. (206 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
ENSUAMP00000002874Ig-like domain-containing protein. (122 aa)
ANGPT1Angiopoietin 1. (452 aa)
EGFEpidermal growth factor. (979 aa)
PFN2Profilin; Belongs to the profilin family. (91 aa)
ENSUAMP00000001068Ig-like domain-containing protein. (174 aa)
LPAR2Lysophosphatidic acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (351 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (198 aa)
APBB1IPAmyloid beta precursor protein binding family B member 1 interacting protein. (596 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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