STRINGSTRING
GCG GCG ENSUAMP00000000176 ENSUAMP00000000176 ENSUAMP00000000513 ENSUAMP00000000513 GPR119 GPR119 ATP1B2 ATP1B2 GRIA4 GRIA4 ENSUAMP00000001454 ENSUAMP00000001454 ENSUAMP00000001579 ENSUAMP00000001579 CNGA2 CNGA2 ENSUAMP00000003355 ENSUAMP00000003355 ENSUAMP00000003358 ENSUAMP00000003358 SSTR1 SSTR1 VIP VIP ENSUAMP00000003880 ENSUAMP00000003880 ENSUAMP00000003964 ENSUAMP00000003964 ENSUAMP00000003974 ENSUAMP00000003974 HCAR1 HCAR1 ACOX1 ACOX1 ENSUAMP00000004725 ENSUAMP00000004725 ENSUAMP00000004728 ENSUAMP00000004728 ATP1B4 ATP1B4 ATP1A1 ATP1A1 CACNA1S CACNA1S CNGB3 CNGB3 ADCY9 ADCY9 ENSUAMP00000005976 ENSUAMP00000005976 PLD2 PLD2 GRIN3B GRIN3B ENSUAMP00000006694 ENSUAMP00000006694 PAK1 PAK1 ENSUAMP00000007288 ENSUAMP00000007288 ATP2B4 ATP2B4 ADORA1 ADORA1 ENSUAMP00000007617 ENSUAMP00000007617 ORAI1 ORAI1 PTCH1 PTCH1 GPR150 GPR150 GNAI3 GNAI3 ADCY2 ADCY2 CALML5 CALML5 RHOB RHOB ADCY3 ADCY3 RRAS RRAS JUN JUN OXT OXT SSTR2 SSTR2 PIK3CA PIK3CA VAV2 VAV2 MAPK8 MAPK8 ATP2B1 ATP2B1 HHIP HHIP CFTR CFTR NPY NPY PIK3R1 PIK3R1 AKT1 AKT1 RAP1B RAP1B ENSUAMP00000010738 ENSUAMP00000010738 PPARA PPARA ENSUAMP00000010849 ENSUAMP00000010849 GLP1R GLP1R NFATC1 NFATC1 ADCYAP1R1 ADCYAP1R1 PPP1R1B PPP1R1B AKT3 AKT3 PLCE1 PLCE1 POMC POMC ENSUAMP00000012276 ENSUAMP00000012276 ENSUAMP00000012405 ENSUAMP00000012405 GABBR1 GABBR1 ENSUAMP00000012593 ENSUAMP00000012593 ENSUAMP00000012611 ENSUAMP00000012611 TULP2 TULP2 ENSUAMP00000013226 ENSUAMP00000013226 LIPE LIPE HTR1B HTR1B ATP2A2 ATP2A2 ADORA2A ADORA2A MAPK1 MAPK1 PPP1CC PPP1CC CALML6 CALML6 SST SST GRIA3 GRIA3 ENSUAMP00000014629 ENSUAMP00000014629 ACOX3 ACOX3 FSHB FSHB ENSUAMP00000015381 ENSUAMP00000015381 DRD1 DRD1 TSHB TSHB ENSUAMP00000015620 ENSUAMP00000015620 DRD5 DRD5 ENSUAMP00000015992 ENSUAMP00000015992 HTR1E HTR1E MC2R MC2R ATP1A2 ATP1A2 ENSUAMP00000016793 ENSUAMP00000016793 MYL9 MYL9 ENSUAMP00000017071 ENSUAMP00000017071 ENSUAMP00000017435 ENSUAMP00000017435 ENSUAMP00000017692 ENSUAMP00000017692 ATP2A3 ATP2A3 ENSUAMP00000017736 ENSUAMP00000017736 CACNA1D CACNA1D PLN PLN ENSUAMP00000017872 ENSUAMP00000017872 RAP1A RAP1A PTGER2 PTGER2 ROCK1 ROCK1 ENSUAMP00000019174 ENSUAMP00000019174 ENSUAMP00000019181 ENSUAMP00000019181 BAD BAD PPP1R14B PPP1R14B ENSUAMP00000019309 ENSUAMP00000019309 PIK3CD PIK3CD CALML4 CALML4 CAMK2B CAMK2B CNGA3 CNGA3 FAP FAP F2R F2R ENSUAMP00000020485 ENSUAMP00000020485 HTR1D HTR1D ADCYAP1 ADCYAP1 HTR4 HTR4 NFKB1 NFKB1 ENSUAMP00000021442 ENSUAMP00000021442 ENSUAMP00000021447 ENSUAMP00000021447 PDE3A PDE3A ENSUAMP00000021520 ENSUAMP00000021520 CALM3 CALM3 NPY1R NPY1R GRIN2A GRIN2A CHRM1 CHRM1 ENSUAMP00000022131 ENSUAMP00000022131 ENSUAMP00000022172 ENSUAMP00000022172 ENSUAMP00000022227 ENSUAMP00000022227 TNNI3 TNNI3 MAPK10 MAPK10 AFDN AFDN DRD2 DRD2 ENSUAMP00000023165 ENSUAMP00000023165 GHSR GHSR PDE4A PDE4A CREB1 CREB1 ATP1B3 ATP1B3 HTR6 HTR6 ROCK2 ROCK2 CREB3L3 CREB3L3 NPPA NPPA BRAF BRAF GLI1 GLI1 ABCC4 ABCC4 ENSUAMP00000025311 ENSUAMP00000025311 HCN4 HCN4 RRAS2 RRAS2 ATP1A4 ATP1A4 ENSUAMP00000025726 ENSUAMP00000025726 PPP1CB PPP1CB ENSUAMP00000026030 ENSUAMP00000026030 FSHR FSHR SUCNR1 SUCNR1 ATP2A1 ATP2A1 SOX10 SOX10 SOX9 SOX9 CREB5 CREB5 FFAR2 FFAR2 ENSUAMP00000026812 ENSUAMP00000026812 RELA RELA CHRM2 CHRM2 GRIN3A GRIN3A PDE4B PDE4B GRIA1 GRIA1 ENSUAMP00000027842 ENSUAMP00000027842 ENSUAMP00000027843 ENSUAMP00000027843 GRIN1 GRIN1 ADCY5 ADCY5 ADCY1 ADCY1 ENSUAMP00000028152 ENSUAMP00000028152 SLC9A1 SLC9A1 GNAS GNAS MAPK9 MAPK9 ENSUAMP00000029031 ENSUAMP00000029031 CACNA1F CACNA1F LHCGR LHCGR TSHR TSHR PTGER3 PTGER3 QPCTL QPCTL GIPR GIPR ENSUAMP00000030280 ENSUAMP00000030280 MAP2K1 MAP2K1 GIP GIP ENSUAMP00000030439 ENSUAMP00000030439 EDN1 EDN1 NFKBIA NFKBIA RAC1 RAC1 RAF1 RAF1 ENSUAMP00000030764 ENSUAMP00000030764 CREBBP CREBBP ENSUAMP00000030787 ENSUAMP00000030787 ATP1B1 ATP1B1 RAC2 RAC2 PDE4D PDE4D CNGA4 CNGA4 ENSUAMP00000031486 ENSUAMP00000031486 VAV1 VAV1 MAPK3 MAPK3 OXTR OXTR RAPGEF4 RAPGEF4 CREB3L4 CREB3L4 EP300 EP300 ADCY4 ADCY4 RAC3 RAC3 ATP2B2 ATP2B2 GHRL GHRL ENSUAMP00000032382 ENSUAMP00000032382 GLI3 GLI3 ADCY7 ADCY7 ENSUAMP00000032618 ENSUAMP00000032618 EDN3 EDN3 ENSUAMP00000032843 ENSUAMP00000032843 ARSI ARSI PDE10A PDE10A PRKACB PRKACB VIPR2 VIPR2 GRIN2B GRIN2B ENSUAMP00000034960 ENSUAMP00000034960 CREB3L1 CREB3L1 ENSUAMP00000035331 ENSUAMP00000035331 CREB3 CREB3 ENSUAMP00000035608 ENSUAMP00000035608 ENSUAMP00000035622 ENSUAMP00000035622 CALM2 CALM2 ADCY6 ADCY6 CGA CGA ENSUAMP00000036154 ENSUAMP00000036154 ADRB2 ADRB2 CNGA1 CNGA1 ENSUAMP00000036508 ENSUAMP00000036508 ATP2B3 ATP2B3 GNAI2 GNAI2 ARAP3 ARAP3 AKT2 AKT2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GCGGlucagon. (179 aa)
ENSUAMP00000000176Protein kinase domain-containing protein. (82 aa)
ENSUAMP00000000513G_PROTEIN_RECEP_F3_4 domain-containing protein. (287 aa)
GPR119G protein-coupled receptor 119; Belongs to the G-protein coupled receptor 1 family. (335 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
GRIA4Glutamate ionotropic receptor AMPA type subunit 4. (957 aa)
ENSUAMP00000001454Uncharacterized protein. (150 aa)
ENSUAMP00000001579Cation_ATPase_N domain-containing protein. (75 aa)
CNGA2Cyclic nucleotide gated channel subunit alpha 2. (664 aa)
ENSUAMP00000003355Uncharacterized protein. (76 aa)
ENSUAMP00000003358SER_THR_PHOSPHATASE domain-containing protein. (106 aa)
SSTR1Somatostatin receptor 1; Belongs to the G-protein coupled receptor 1 family. (355 aa)
VIPVasoactive intestinal peptide. (170 aa)
ENSUAMP00000003880Uncharacterized protein. (91 aa)
ENSUAMP00000003964FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (59 aa)
ENSUAMP00000003974G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (362 aa)
HCAR1Hydroxycarboxylic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (337 aa)
ACOX1Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (655 aa)
ENSUAMP00000004725G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (253 aa)
ENSUAMP00000004728G_PROTEIN_RECEP_F1_2 domain-containing protein. (155 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (348 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1021 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1872 aa)
CNGB3Cyclic nucleotide gated channel subunit beta 3. (782 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1338 aa)
ENSUAMP00000005976Uncharacterized protein. (94 aa)
PLD2Phospholipase. (1025 aa)
GRIN3BGlutamate ionotropic receptor NMDA type subunit 3B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1001 aa)
ENSUAMP00000006694SER_THR_PHOSPHATASE domain-containing protein. (148 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
ENSUAMP00000007288Ca_chan_IQ domain-containing protein. (832 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1260 aa)
ADORA1Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (326 aa)
ENSUAMP00000007617Protein kinase domain-containing protein. (271 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (305 aa)
PTCH1Patched 1. (1453 aa)
GPR150G protein-coupled receptor 150. (432 aa)
GNAI3G protein subunit alpha i3. (295 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1112 aa)
CALML5Calmodulin like 5. (156 aa)
RHOBRas homolog family member B. (172 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (973 aa)
RRASRAS related. (218 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
OXTOxytocin/neurophysin I prepropeptide; Belongs to the vasopressin/oxytocin family. (180 aa)
SSTR2Somatostatin receptor 2; Belongs to the G-protein coupled receptor 1 family. (369 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
VAV2Vav guanine nucleotide exchange factor 2. (855 aa)
MAPK8Mitogen-activated protein kinase. (456 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1214 aa)
HHIPHedgehog interacting protein. (508 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1475 aa)
NPYNeuropeptide Y. (90 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (676 aa)
AKT1Non-specific serine/threonine protein kinase. (572 aa)
RAP1BRAP1B, member of RAS oncogene family. (184 aa)
ENSUAMP00000010738Uncharacterized protein. (181 aa)
PPARAPeroxisome proliferator activated receptor alpha. (503 aa)
ENSUAMP00000010849PDE4_UCR domain-containing protein. (136 aa)
GLP1RGlucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (482 aa)
NFATC1Nuclear factor of activated T cells 1. (931 aa)
ADCYAP1R1ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (440 aa)
PPP1R1BProtein phosphatase 1 regulatory inhibitor subunit 1B. (169 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PLCE1Phosphoinositide phospholipase C. (1942 aa)
POMCProopiomelanocortin. (223 aa)
ENSUAMP00000012276B30.2/SPRY domain-containing protein. (334 aa)
ENSUAMP00000012405Uncharacterized protein. (110 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (844 aa)
ENSUAMP00000012593PH domain-containing protein. (647 aa)
ENSUAMP00000012611Sushi domain-containing protein. (238 aa)
TULP2Tubby-like protein; Belongs to the TUB family. (468 aa)
ENSUAMP00000013226Cys_knot domain-containing protein. (140 aa)
LIPELipase E, hormone sensitive type. (805 aa)
HTR1B5-hydroxytryptamine receptor 1B. (389 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (409 aa)
MAPK1Mitogen-activated protein kinase. (364 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (326 aa)
CALML6Calmodulin like 6. (180 aa)
SSTSomatostatin. (116 aa)
GRIA3Glutamate ionotropic receptor AMPA type subunit 3. (601 aa)
ENSUAMP00000014629Uncharacterized protein. (105 aa)
ACOX3Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (700 aa)
FSHBFollicle stimulating hormone subunit beta. (129 aa)
ENSUAMP00000015381ANF_receptor domain-containing protein. (158 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
TSHBThyroid stimulating hormone subunit beta. (138 aa)
ENSUAMP00000015620Uncharacterized protein. (577 aa)
DRD5Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family. (474 aa)
ENSUAMP00000015992G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (246 aa)
HTR1E5-hydroxytryptamine receptor 1E. (365 aa)
MC2RMelanocortin 2 receptor. (297 aa)
ATP1A2ATPase Na+/K+ transporting subunit alpha 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1127 aa)
ENSUAMP00000016793BZIP domain-containing protein. (179 aa)
MYL9Myosin light chain 9. (172 aa)
ENSUAMP00000017071G_PROTEIN_RECEP_F1_2 domain-containing protein. (366 aa)
ENSUAMP00000017435Uncharacterized protein. (459 aa)
ENSUAMP00000017692Uncharacterized protein. (704 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (982 aa)
ENSUAMP00000017736Cation_ATPase_N domain-containing protein. (54 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2160 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
ENSUAMP00000017872DH domain-containing protein. (687 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
PTGER2Prostaglandin E receptor 2; Belongs to the G-protein coupled receptor 1 family. (347 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1365 aa)
ENSUAMP00000019174CaMKII_AD domain-containing protein. (267 aa)
ENSUAMP00000019181Protein kinase domain-containing protein. (206 aa)
BADBCL2 associated agonist of cell death. (168 aa)
PPP1R14BProtein phosphatase 1 regulatory inhibitor subunit 14B. (147 aa)
ENSUAMP00000019309Calponin-homology (CH) domain-containing protein. (82 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1041 aa)
CALML4Calmodulin like 4. (153 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (589 aa)
CNGA3Cyclic nucleotide gated channel subunit alpha 3. (684 aa)
FAPFibroblast activation protein alpha; Belongs to the peptidase S9B family. (724 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (427 aa)
ENSUAMP00000020485Protein kinase domain-containing protein. (108 aa)
HTR1D5-hydroxytryptamine receptor 1D. (377 aa)
ADCYAP1Adenylate cyclase activating polypeptide 1. (176 aa)
HTR45-hydroxytryptamine receptor 4; Belongs to the G-protein coupled receptor 1 family. (384 aa)
NFKB1Nuclear factor kappa B subunit 1. (972 aa)
ENSUAMP00000021442Uncharacterized protein. (307 aa)
ENSUAMP00000021447Cyclic nucleotide-binding domain-containing protein. (846 aa)
PDE3APhosphodiesterase. (777 aa)
ENSUAMP00000021520Uncharacterized protein. (210 aa)
CALM3Calmodulin 3; Belongs to the calmodulin family. (149 aa)
NPY1RNeuropeptide Y receptor Y1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1427 aa)
CHRM1Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (460 aa)
ENSUAMP00000022131Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (636 aa)
ENSUAMP00000022172Uncharacterized protein. (157 aa)
ENSUAMP00000022227Uncharacterized protein. (64 aa)
TNNI3Troponin I3, cardiac type. (211 aa)
MAPK10Mitogen-activated protein kinase. (422 aa)
AFDNAfadin, adherens junction formation factor. (1540 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
ENSUAMP00000023165Protein kinase domain-containing protein. (270 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
PDE4APhosphodiesterase 4A; Belongs to the cyclic nucleotide phosphodiesterase family. (872 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (280 aa)
HTR65-hydroxytryptamine receptor 6; Belongs to the G-protein coupled receptor 1 family. (443 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1384 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (457 aa)
NPPANatriuretic peptide A. (182 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (728 aa)
GLI1GLI family zinc finger 1. (1105 aa)
ABCC4ATP binding cassette subfamily C member 4. (942 aa)
ENSUAMP00000025311Uncharacterized protein. (295 aa)
HCN4Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (998 aa)
RRAS2RAS related 2. (204 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1011 aa)
ENSUAMP00000025726annotation not available (113 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
ENSUAMP00000026030Uncharacterized protein. (236 aa)
FSHRFollicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (691 aa)
SUCNR1Succinate receptor 1; Belongs to the G-protein coupled receptor 1 family. (318 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1060 aa)
SOX10SRY-box transcription factor 10. (465 aa)
SOX9SRY-box transcription factor 9. (484 aa)
CREB5cAMP responsive element binding protein 5. (327 aa)
FFAR2Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (335 aa)
ENSUAMP00000026812G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (328 aa)
RELARELA proto-oncogene, NF-kB subunit. (508 aa)
CHRM2Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (466 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A. (1103 aa)
PDE4BPhosphodiesterase. (682 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (906 aa)
ENSUAMP00000027842Uncharacterized protein. (99 aa)
ENSUAMP00000027843Uncharacterized protein. (119 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (814 aa)
ADCY5Adenylate cyclase 5. (940 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1119 aa)
ENSUAMP00000028152SH3 domain-containing protein. (120 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (816 aa)
GNASGNAS complex locus. (994 aa)
MAPK9Mitogen-activated protein kinase. (433 aa)
ENSUAMP00000029031Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1866 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (673 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
PTGER3Prostaglandin E receptor 3. (387 aa)
QPCTLGlutaminyl-peptide cyclotransferase like. (404 aa)
GIPRGastric inhibitory polypeptide receptor; Belongs to the G-protein coupled receptor 2 family. (466 aa)
ENSUAMP00000030280Protein kinase domain-containing protein. (206 aa)
MAP2K1Protein kinase domain-containing protein. (216 aa)
GIPGastric inhibitory polypeptide. (176 aa)
ENSUAMP00000030439Uncharacterized protein. (257 aa)
EDN1Endothelin 1. (202 aa)
NFKBIANFKB inhibitor alpha. (314 aa)
RAC1Rac family small GTPase 1. (229 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (564 aa)
ENSUAMP00000030764Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1123 aa)
CREBBPCREB binding protein. (2333 aa)
ENSUAMP00000030787Uncharacterized protein. (84 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
RAC2Rac family small GTPase 2. (192 aa)
PDE4DPhosphodiesterase. (585 aa)
CNGA4Cyclic nucleotide gated channel subunit alpha 4. (576 aa)
ENSUAMP00000031486Calponin-homology (CH) domain-containing protein. (86 aa)
VAV1Vav guanine nucleotide exchange factor 1. (774 aa)
MAPK3Mitogen-activated protein kinase. (354 aa)
OXTROxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (390 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4. (1019 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (247 aa)
EP300E1A binding protein p300. (2399 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
RAC3Rac family small GTPase 3. (202 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1250 aa)
GHRLGhrelin and obestatin prepropeptide. (134 aa)
ENSUAMP00000032382CaMKII_AD domain-containing protein. (189 aa)
GLI3GLI family zinc finger 3. (1413 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1078 aa)
ENSUAMP00000032618Uncharacterized protein. (68 aa)
EDN3Endothelin 3. (198 aa)
ENSUAMP00000032843Uncharacterized protein. (186 aa)
ARSIArylsulfatase family member I. (573 aa)
PDE10APhosphodiesterase. (525 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (361 aa)
VIPR2Vasoactive intestinal peptide receptor 2; Belongs to the G-protein coupled receptor 2 family. (434 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
ENSUAMP00000034960C2H2-type domain-containing protein. (123 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (520 aa)
ENSUAMP00000035331Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (506 aa)
CREB3cAMP responsive element binding protein 3. (352 aa)
ENSUAMP00000035608Uncharacterized protein. (85 aa)
ENSUAMP00000035622Uncharacterized protein. (662 aa)
CALM2Calmodulin 2; Belongs to the calmodulin family. (163 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1164 aa)
CGAGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (120 aa)
ENSUAMP00000036154Phosphodiesterase. (696 aa)
ADRB2Adrenoceptor beta 2. (418 aa)
CNGA1Cyclic nucleotide gated channel subunit alpha 1. (676 aa)
ENSUAMP00000036508Guanylate cyclase domain-containing protein. (363 aa)
ATP2B3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1254 aa)
GNAI2G protein subunit alpha i2. (436 aa)
ARAP3ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3. (1537 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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