STRINGSTRING
TNF TNF CCR9 CCR9 ENSUAMP00000001881 ENSUAMP00000001881 CCL24 CCL24 CCR5 CCR5 CCR2 CCR2 IL24 IL24 CXCL11 CXCL11 IL20 IL20 IL18RAP IL18RAP IL19 IL19 IL10 IL10 IL18R1 IL18R1 IL10RB IL10RB CXCR5 CXCR5 CCR4 CCR4 CXCL13 CXCL13 TNFRSF14 TNFRSF14 IL20RB IL20RB TNFRSF1B TNFRSF1B CXCL10 CXCL10 ENSUAMP00000032598 ENSUAMP00000032598 CSF1R CSF1R CXCR4 CXCR4 ENSUAMP00000031760 ENSUAMP00000031760 ENSUAMP00000031758 ENSUAMP00000031758 RUFY4 RUFY4 ENSUAMP00000031718 ENSUAMP00000031718 IL6 IL6 TNFSF14 TNFSF14 IL6ST IL6ST ENSUAMP00000029827 ENSUAMP00000029827 IL2 IL2 TNFRSF1A TNFRSF1A ENSUAMP00000029256 ENSUAMP00000029256 ENSUAMP00000029255 ENSUAMP00000029255 CXCR3 CXCR3 CSF1 CSF1 ENSUAMP00000028937 ENSUAMP00000028937 CCR6 CCR6 IL22RA1 IL22RA1 CCL20 CCL20 IL2RB IL2RB IL18 IL18 TNFSF10 TNFSF10 CX3CR1 CX3CR1 CCL26 CCL26 CCL21 CCL21 CCL19 CCL19 ENSUAMP00000022367 ENSUAMP00000022367 CCL27 CCL27 IL20RA IL20RA PPBP PPBP ENSUAMP00000022203 ENSUAMP00000022203 CX3CL1 CX3CL1 CCL22 CCL22 CXCL8 CXCL8 CCR7 CCR7 CCR8 CCR8 ACKR3 ACKR3 IL6R IL6R CXCL12 CXCL12 ENSUAMP00000017283 ENSUAMP00000017283 CXCL14 CXCL14 ENSUAMP00000017060 ENSUAMP00000017060 ENSUAMP00000017057 ENSUAMP00000017057 ENSUAMP00000012035 ENSUAMP00000012035 ENSUAMP00000012037 ENSUAMP00000012037 CCL2 CCL2 CCL7 CCL7 CCL8 CCL8 CCL13 CCL13 ENSUAMP00000012122 ENSUAMP00000012122 ENSUAMP00000008680 ENSUAMP00000008680 ENSUAMP00000012767 ENSUAMP00000012767 CCR1 CCR1 XCR1 XCR1 ENSUAMP00000003236 ENSUAMP00000003236 LTA LTA CCR10 CCR10 CCL28 CCL28 ENSUAMP00000012032 ENSUAMP00000012032 IL34 IL34 ENSUAMP00000006128 ENSUAMP00000006128 CCL5 CCL5 ENSUAMP00000005556 ENSUAMP00000005556 ENSUAMP00000005553 ENSUAMP00000005553 ENSUAMP00000005552 ENSUAMP00000005552 IL10RA IL10RA CCR3 CCR3 ACKR4 ACKR4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (230 aa)
CCR9C-C motif chemokine receptor 9; Belongs to the G-protein coupled receptor 1 family. (368 aa)
ENSUAMP00000001881Uncharacterized protein. (124 aa)
CCL24C-C motif chemokine ligand 24. (119 aa)
CCR5C-C motif chemokine receptor 5 (gene/pseudogene); Belongs to the G-protein coupled receptor 1 family. (352 aa)
CCR2C-C motif chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (373 aa)
IL24Interleukin 24. (211 aa)
CXCL11C-X-C motif chemokine. (96 aa)
IL20Interleukin 20. (176 aa)
IL18RAPInterleukin 18 receptor accessory protein. (573 aa)
IL19Interleukin 19. (177 aa)
IL10Interleukin 10. (178 aa)
IL18R1Interleukin 18 receptor 1. (541 aa)
IL10RBInterleukin 10 receptor subunit beta. (375 aa)
CXCR5C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family. (371 aa)
CCR4C-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (360 aa)
CXCL13C-X-C motif chemokine ligand 13. (110 aa)
TNFRSF14TNF receptor superfamily member 14. (280 aa)
IL20RBInterleukin 20 receptor subunit beta. (283 aa)
TNFRSF1BTNF receptor superfamily member 1B. (460 aa)
CXCL10C-X-C motif chemokine. (98 aa)
ENSUAMP00000032598SCY domain-containing protein. (64 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (967 aa)
CXCR4C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (353 aa)
ENSUAMP00000031760G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (355 aa)
ENSUAMP00000031758G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (366 aa)
RUFY4RUN and FYVE domain containing 4. (558 aa)
ENSUAMP00000031718SCY domain-containing protein. (112 aa)
IL6Interleukin 6. (212 aa)
TNFSF14TNF superfamily member 14; Belongs to the tumor necrosis factor family. (238 aa)
IL6STInterleukin 6 signal transducer. (918 aa)
ENSUAMP00000029827Fibronectin type-III domain-containing protein. (374 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (155 aa)
TNFRSF1ATNF receptor superfamily member 1A. (502 aa)
ENSUAMP00000029256TNFR-Cys domain-containing protein. (148 aa)
ENSUAMP00000029255Uncharacterized protein. (203 aa)
CXCR3C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (369 aa)
CSF1Colony stimulating factor 1. (518 aa)
ENSUAMP00000028937SCY domain-containing protein. (150 aa)
CCR6C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (381 aa)
IL22RA1Interleukin 22 receptor subunit alpha 1. (579 aa)
CCL20C-C motif chemokine. (96 aa)
IL2RBInterleukin 2 receptor subunit beta. (552 aa)
IL18Interleukin 18. (167 aa)
TNFSF10Tumor necrosis factor ligand superfamily member. (289 aa)
CX3CR1C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (356 aa)
CCL26C-C motif chemokine. (92 aa)
CCL21C-C motif chemokine ligand 21. (138 aa)
CCL19C-C motif chemokine. (100 aa)
ENSUAMP00000022367Uncharacterized protein. (87 aa)
CCL27C-C motif chemokine ligand 27. (133 aa)
IL20RAInterleukin 20 receptor subunit alpha. (553 aa)
PPBPC-X-C motif chemokine. (128 aa)
ENSUAMP00000022203C-X-C motif chemokine. (141 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (392 aa)
CCL22C-C motif chemokine. (93 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (373 aa)
CCR8C-C motif chemokine receptor 8; Belongs to the G-protein coupled receptor 1 family. (354 aa)
ACKR3Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (362 aa)
IL6RInterleukin 6 receptor. (496 aa)
CXCL12SCY domain-containing protein; Belongs to the intercrine alpha (chemokine CxC) family. (109 aa)
ENSUAMP00000017283Uncharacterized protein. (60 aa)
CXCL14C-X-C motif chemokine ligand 14. (98 aa)
ENSUAMP00000017060C-X-C motif chemokine. (107 aa)
ENSUAMP00000017057C-X-C motif chemokine. (107 aa)
ENSUAMP00000012035C-C motif chemokine. (93 aa)
ENSUAMP00000012037C-C motif chemokine. (92 aa)
CCL2C-C motif chemokine. (101 aa)
CCL7C-C motif chemokine. (99 aa)
CCL8C-C motif chemokine. (99 aa)
CCL13C-C motif chemokine. (98 aa)
ENSUAMP00000012122C-C motif chemokine. (94 aa)
ENSUAMP00000008680Uncharacterized protein. (251 aa)
ENSUAMP00000012767C-C motif chemokine. (101 aa)
CCR1C-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (355 aa)
XCR1X-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (331 aa)
ENSUAMP00000003236C-X-C motif chemokine. (106 aa)
LTALymphotoxin alpha; Belongs to the tumor necrosis factor family. (204 aa)
CCR10C-C motif chemokine receptor 10; Belongs to the G-protein coupled receptor 1 family. (363 aa)
CCL28C-C motif chemokine. (114 aa)
ENSUAMP00000012032C-C motif chemokine. (93 aa)
IL34Interleukin 34. (236 aa)
ENSUAMP00000006128annotation not available (106 aa)
CCL5C-C motif chemokine. (116 aa)
ENSUAMP00000005556SCY domain-containing protein. (133 aa)
ENSUAMP00000005553SCY domain-containing protein. (118 aa)
ENSUAMP00000005552SCY domain-containing protein. (93 aa)
IL10RAInterleukin 10 receptor subunit alpha. (575 aa)
CCR3C-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (359 aa)
ACKR4Atypical chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (350 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
Server load: low (16%) [HD]