Your Input: | |||||
PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1166 aa) | ||||
S1PR1 | Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa) | ||||
ENSUAMP00000005976 | Uncharacterized protein. (94 aa) | ||||
PLD2 | Phospholipase. (1025 aa) | ||||
ENSUAMP00000006289 | Uncharacterized protein. (158 aa) | ||||
ABCC1 | ATP binding cassette subfamily C member 1. (1415 aa) | ||||
SGPP1 | Sphingosine-1-phosphate phosphatase 1. (263 aa) | ||||
MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1212 aa) | ||||
ADORA1 | Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (326 aa) | ||||
PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (651 aa) | ||||
GNAI3 | G protein subunit alpha i3. (295 aa) | ||||
ENSUAMP00000008403 | TLC domain-containing protein. (239 aa) | ||||
RHOB | Ras homolog family member B. (172 aa) | ||||
RAC2 | Rac family small GTPase 2. (192 aa) | ||||
SMPD1 | Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (625 aa) | ||||
MAPK3 | Mitogen-activated protein kinase. (354 aa) | ||||
ENSUAMP00000031719 | Uncharacterized protein. (627 aa) | ||||
DEGS1 | Delta 4-desaturase, sphingolipid 1. (323 aa) | ||||
RAC3 | Rac family small GTPase 3. (202 aa) | ||||
SGPP2 | Sphingosine-1-phosphate phosphatase 2. (348 aa) | ||||
MAPK14 | Mitogen-activated protein kinase. (360 aa) | ||||
MAPK13 | Mitogen-activated protein kinase. (366 aa) | ||||
ENSUAMP00000032533 | Uncharacterized protein. (127 aa) | ||||
ENSUAMP00000032535 | Uncharacterized protein. (145 aa) | ||||
NOS3 | Nitric oxide synthase; Produces nitric oxide (NO). (1202 aa) | ||||
ENSUAMP00000032923 | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (387 aa) | ||||
PTK6 | Tyrosine-protein kinase. (482 aa) | ||||
PPP2R2D | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (449 aa) | ||||
AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) | ||||
ENSUAMP00000011147 | Ion_trans domain-containing protein. (118 aa) | ||||
ENSUAMP00000011028 | Uncharacterized protein. (50 aa) | ||||
NSMAF | Neutral sphingomyelinase activation associated factor. (791 aa) | ||||
ENSUAMP00000028179 | CSD domain-containing protein. (89 aa) | ||||
PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1136 aa) | ||||
MAPK9 | Mitogen-activated protein kinase. (433 aa) | ||||
CERS4 | Ceramide synthase 4. (461 aa) | ||||
ENSUAMP00000029031 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa) | ||||
SPTLC2 | Serine palmitoyltransferase long chain base subunit 2. (561 aa) | ||||
TNFRSF1A | TNF receptor superfamily member 1A. (502 aa) | ||||
SPHK1 | Sphingosine kinase 1. (387 aa) | ||||
SPTLC1 | Serine palmitoyltransferase long chain base subunit 1. (517 aa) | ||||
ENSUAMP00000030280 | Protein kinase domain-containing protein. (206 aa) | ||||
MAP2K1 | Protein kinase domain-containing protein. (216 aa) | ||||
PPP2R3C | Protein phosphatase 2 regulatory subunit B''gamma. (450 aa) | ||||
RAC1 | Rac family small GTPase 1. (229 aa) | ||||
ENSUAMP00000030716 | Uncharacterized protein. (98 aa) | ||||
RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (564 aa) | ||||
ENSUAMP00000030787 | Uncharacterized protein. (84 aa) | ||||
AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) | ||||
GNAI2 | G protein subunit alpha i2. (436 aa) | ||||
ENSUAMP00000036324 | Uncharacterized protein. (189 aa) | ||||
ENSUAMP00000036253 | Protein kinase domain-containing protein. (66 aa) | ||||
SGMS2 | Sphingomyelin synthase 2. (365 aa) | ||||
ENSUAMP00000035681 | Protein kinase domain-containing protein. (217 aa) | ||||
ENSUAMP00000035331 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (506 aa) | ||||
CERS2 | Ceramide synthase 2. (380 aa) | ||||
FCER1A | Fc fragment of IgE receptor Ia. (274 aa) | ||||
ACER1 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (263 aa) | ||||
ENSUAMP00000033965 | Homeobox domain-containing protein. (210 aa) | ||||
ADAMTS19 | ADAM metallopeptidase with thrombospondin type 1 motif 19. (792 aa) | ||||
FCER1G | Fc fragment of IgE receptor Ig. (80 aa) | ||||
SRMS | Tyrosine-protein kinase. (492 aa) | ||||
DEGS2 | Delta 4-desaturase, sphingolipid 2. (323 aa) | ||||
OPRD1 | Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (367 aa) | ||||
ENSUAMP00000028178 | Uncharacterized protein. (311 aa) | ||||
ENSUAMP00000012405 | Uncharacterized protein. (110 aa) | ||||
PPP2R1A | Protein phosphatase 2 scaffold subunit Aalpha. (589 aa) | ||||
BAX | BCL2 associated X, apoptosis regulator. (205 aa) | ||||
SPHK2 | Sphingosine kinase 2. (662 aa) | ||||
BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (196 aa) | ||||
MAPK1 | Mitogen-activated protein kinase. (364 aa) | ||||
ERAS | ES cell expressed Ras. (219 aa) | ||||
ASAH1 | N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family. (330 aa) | ||||
ENSUAMP00000014629 | Uncharacterized protein. (105 aa) | ||||
ENSUAMP00000014648 | Adenosine receptor A3; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (318 aa) | ||||
ENSUAMP00000014650 | G_PROTEIN_RECEP_F1_2 domain-containing protein. (199 aa) | ||||
ENSUAMP00000014661 | Uncharacterized protein. (241 aa) | ||||
ENSUAMP00000014981 | EF-hand domain-containing protein. (176 aa) | ||||
PPP2R5B | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa) | ||||
TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (230 aa) | ||||
ENSUAMP00000015993 | Uncharacterized protein. (98 aa) | ||||
BCL2 | BCL2 apoptosis regulator. (205 aa) | ||||
PDPK1 | 3-phosphoinositide dependent protein kinase 1. (531 aa) | ||||
MAPK12 | Mitogen-activated protein kinase 12. (373 aa) | ||||
MAPK11 | Mitogen-activated protein kinase. (357 aa) | ||||
ENSUAMP00000017375 | Uncharacterized protein. (208 aa) | ||||
ENSUAMP00000017435 | Uncharacterized protein. (459 aa) | ||||
ENSUAMP00000017692 | Uncharacterized protein. (704 aa) | ||||
ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1365 aa) | ||||
PPP2R3A | Protein phosphatase 2 regulatory subunit B''alpha. (1153 aa) | ||||
PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1172 aa) | ||||
PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1041 aa) | ||||
TRADD | TNFRSF1A associated via death domain. (314 aa) | ||||
ENSUAMP00000019938 | Uncharacterized protein. (193 aa) | ||||
PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (714 aa) | ||||
PPP2R5A | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (498 aa) | ||||
KRAS | KRAS proto-oncogene, GTPase. (188 aa) | ||||
GNAQ | G protein subunit alpha q. (352 aa) | ||||
CERS3 | Ceramide synthase 3. (402 aa) | ||||
NFKB1 | Nuclear factor kappa B subunit 1. (972 aa) | ||||
PPP2R2B | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (443 aa) | ||||
ENSUAMP00000022131 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (636 aa) | ||||
PPP2R5D | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (601 aa) | ||||
ENSUAMP00000022172 | Uncharacterized protein. (157 aa) | ||||
ENSUAMP00000022227 | Uncharacterized protein. (64 aa) | ||||
PPP2R5E | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (504 aa) | ||||
MAPK10 | Mitogen-activated protein kinase. (422 aa) | ||||
SMPD2 | Sphingomyelin phosphodiesterase 2. (423 aa) | ||||
ENSUAMP00000023048 | PB1 domain-containing protein. (123 aa) | ||||
PPP2CA | Serine/threonine-protein phosphatase. (309 aa) | ||||
S1PR5 | Sphingosine-1-phosphate receptor 5. (398 aa) | ||||
ENSUAMP00000023976 | Uncharacterized protein. (158 aa) | ||||
PPP2R5C | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (503 aa) | ||||
ROCK2 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1384 aa) | ||||
ENSUAMP00000025300 | Non-specific serine/threonine protein kinase. (254 aa) | ||||
BDKRB2 | Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. (392 aa) | ||||
ENSUAMP00000025837 | Ceramidse_alk_C domain-containing protein. (150 aa) | ||||
ENSUAMP00000026182 | Abhydrolase_3 domain-containing protein. (237 aa) | ||||
S1PR2 | Sphingosine-1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family. (352 aa) | ||||
PPP2R2A | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (458 aa) | ||||
RELA | RELA proto-oncogene, NF-kB subunit. (508 aa) | ||||
ENSUAMP00000026993 | Uncharacterized protein. (118 aa) | ||||
PLCB1 | Phosphoinositide phospholipase C. (658 aa) | ||||
AKT1 | Non-specific serine/threonine protein kinase. (572 aa) | ||||
PRKCA | Protein kinase C alpha; Belongs to the protein kinase superfamily. (484 aa) | ||||
PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (676 aa) | ||||
ENSUAMP00000009775 | C2 domain-containing protein. (151 aa) | ||||
ENSUAMP00000009491 | C2 tensin-type domain-containing protein. (179 aa) | ||||
MAPK8 | Mitogen-activated protein kinase. (456 aa) | ||||
PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) | ||||
ENSUAMP00000027063 | Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (410 aa) | ||||
IFITM10 | Interferon induced transmembrane protein 10. (225 aa) | ||||
FYN | Tyrosine-protein kinase. (537 aa) | ||||
PPP2CB | Serine/threonine-protein phosphatase. (309 aa) | ||||
CERS5 | Ceramide synthase 5. (389 aa) | ||||
ACER2 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa) | ||||
GNA12 | G protein subunit alpha 12. (350 aa) | ||||
S1PR3 | Sphingosine-1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (378 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa) | ||||
PPP2R2C | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (425 aa) | ||||
SGPL1 | Sphingosine-1-phosphate lyase 1. (568 aa) | ||||
GAB2 | GRB2 associated binding protein 2. (665 aa) | ||||
TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (523 aa) | ||||
ENSUAMP00000003693 | Uncharacterized protein. (166 aa) | ||||
SPTLC3 | Serine palmitoyltransferase long chain base subunit 3. (536 aa) | ||||
ENSUAMP00000003880 | Uncharacterized protein. (91 aa) | ||||
ENSUAMP00000004579 | Abhydrolase_3 domain-containing protein. (224 aa) |