STRINGSTRING
APC APC ENSUAMP00000000176 ENSUAMP00000000176 ENSUAMP00000000906 ENSUAMP00000000906 TP53 TP53 AMIGO2 AMIGO2 AXIN2 AXIN2 ENSUAMP00000001392 ENSUAMP00000001392 WNT6 WNT6 PKP4 PKP4 LRP6 LRP6 ENSUAMP00000001958 ENSUAMP00000001958 ENSUAMP00000001991 ENSUAMP00000001991 FZD2 FZD2 LGR5 LGR5 WNT11 WNT11 SENP2 SENP2 ENSUAMP00000002778 ENSUAMP00000002778 WNT8B WNT8B SNAPIN SNAPIN DKK1 DKK1 SFRP1 SFRP1 ENSUAMP00000004203 ENSUAMP00000004203 ENSUAMP00000004313 ENSUAMP00000004313 ENSUAMP00000004444 ENSUAMP00000004444 ENSUAMP00000004535 ENSUAMP00000004535 PLCB2 PLCB2 WIF1 WIF1 ENSUAMP00000005084 ENSUAMP00000005084 PRICKLE1 PRICKLE1 ENSUAMP00000005842 ENSUAMP00000005842 ENSUAMP00000005976 ENSUAMP00000005976 ENSUAMP00000006331 ENSUAMP00000006331 ENSUAMP00000006334 ENSUAMP00000006334 RUVBL1 RUVBL1 CHD8 CHD8 DVL3 DVL3 ENSUAMP00000006884 ENSUAMP00000006884 ENSUAMP00000007617 ENSUAMP00000007617 RSPO4 RSPO4 PRKCB PRKCB TCF7 TCF7 SKP1 SKP1 WNT2B WNT2B ENSUAMP00000007849 ENSUAMP00000007849 DAAM1 DAAM1 LRRC24 LRRC24 PPP3CA PPP3CA NFATC4 NFATC4 TES TES RHOB RHOB JUN JUN ENSUAMP00000009120 ENSUAMP00000009120 PSEN1 PSEN1 MAPK8 MAPK8 ENSUAMP00000009333 ENSUAMP00000009333 ENSUAMP00000009335 ENSUAMP00000009335 WNT2 WNT2 PPP3CB PPP3CB PRKCA PRKCA RYK RYK PLCB1 PLCB1 FZD4 FZD4 SFRP4 SFRP4 ENSUAMP00000011236 ENSUAMP00000011236 NFATC1 NFATC1 FZD5 FZD5 GSK3B GSK3B ENSUAMP00000012266 ENSUAMP00000012266 WNT3A WNT3A WNT9A WNT9A ENSUAMP00000012405 ENSUAMP00000012405 ENSUAMP00000012729 ENSUAMP00000012729 SFRP5 SFRP5 ENSUAMP00000013482 ENSUAMP00000013482 ENSUAMP00000014208 ENSUAMP00000014208 ENSUAMP00000014210 ENSUAMP00000014210 CBY3 CBY3 CBY1 CBY1 ENSUAMP00000014717 ENSUAMP00000014717 C17orf64 C17orf64 LGR4 LGR4 ENSUAMP00000015431 ENSUAMP00000015431 ZNRF3 ZNRF3 WNT7B WNT7B DVL1 DVL1 ENSUAMP00000016536 ENSUAMP00000016536 EFEMP1 EFEMP1 PORCN PORCN ENSUAMP00000016912 ENSUAMP00000016912 ELP3 ELP3 DKK2 DKK2 CTNNB1 CTNNB1 INVS INVS RSPO1 RSPO1 PPARD PPARD TLE4 TLE4 WNT10A WNT10A FHDC1 FHDC1 SMAD4 SMAD4 APC2 APC2 DVL2 DVL2 NKD2 NKD2 TBL1XR1 TBL1XR1 ENSUAMP00000019174 ENSUAMP00000019174 ENSUAMP00000019181 ENSUAMP00000019181 PLCB3 PLCB3 ENSUAMP00000019295 ENSUAMP00000019295 CTNNBIP1 CTNNBIP1 RSPO2 RSPO2 DAND5 DAND5 FZD6 FZD6 SERPINF1 SERPINF1 CAMK2B CAMK2B AXIN1 AXIN1 ENSUAMP00000020051 ENSUAMP00000020051 ENSUAMP00000020288 ENSUAMP00000020288 PRKCG PRKCG NFATC3 NFATC3 DKK4 DKK4 ENSUAMP00000020585 ENSUAMP00000020585 MMP7 MMP7 FZD9 FZD9 CSNK2A2 CSNK2A2 GPC4 GPC4 BAMBI BAMBI WDR92 WDR92 ENSUAMP00000021954 ENSUAMP00000021954 WNT16 WNT16 FZD3 FZD3 ENSUAMP00000022336 ENSUAMP00000022336 ENSUAMP00000022339 ENSUAMP00000022339 MAPK10 MAPK10 SOST SOST WNT5A WNT5A NLK NLK CCN4 CCN4 ROCK2 ROCK2 FRZB FRZB WNT8A WNT8A CSNK1A1 CSNK1A1 ENSUAMP00000025300 ENSUAMP00000025300 LRP5 LRP5 PRICKLE2 PRICKLE2 TCF7L2 TCF7L2 LGR6 LGR6 WNT4 WNT4 SMAD3 SMAD3 FOSL1 FOSL1 FIBP FIBP EFEMP2 EFEMP2 CXXC4 CXXC4 CTBP1 CTBP1 ENSUAMP00000027679 ENSUAMP00000027679 FZD10 FZD10 VANGL2 VANGL2 ENSUAMP00000028248 ENSUAMP00000028248 ENSUAMP00000028314 ENSUAMP00000028314 VANGL1 VANGL1 PLCB4 PLCB4 MAPK9 MAPK9 CUL1 CUL1 DAAM2 DAAM2 ENSUAMP00000029470 ENSUAMP00000029470 CER1 CER1 RAC1 RAC1 CREBBP CREBBP TLE3 TLE3 RBX1 RBX1 RAC2 RAC2 BTRC BTRC CHD6 CHD6 MYC MYC EP300 EP300 MAP3K7 MAP3K7 NOTUM NOTUM LRRC45 LRRC45 RAC3 RAC3 FBXW11 FBXW11 NKD1 NKD1 ENSUAMP00000032382 ENSUAMP00000032382 CCND1 CCND1 PPP3CC PPP3CC FZD7 FZD7 ARSI ARSI ENSUAMP00000033172 ENSUAMP00000033172 ENSUAMP00000033173 ENSUAMP00000033173 ENSUAMP00000033199 ENSUAMP00000033199 KCNK1 KCNK1 PRKACB PRKACB CHD7 CHD7 ENSUAMP00000034574 ENSUAMP00000034574 ROR2 ROR2 CXXC5 CXXC5 ENSUAMP00000035281 ENSUAMP00000035281 RSPO3 RSPO3 WNT1 WNT1 WNT10B WNT10B SIAH2 SIAH2 CHD1 CHD1 WNT7A WNT7A ENSUAMP00000035777 ENSUAMP00000035777 WNT3 WNT3 WNT9B WNT9B FZD1 FZD1 TCF7L1 TCF7L1 ENSUAMP00000036463 ENSUAMP00000036463 SOX17 SOX17 CCND3 CCND3 FRAT2 FRAT2 ENSUAMP00000037320 ENSUAMP00000037320
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APCAPC regulator of WNT signaling pathway. (2832 aa)
ENSUAMP00000000176Protein kinase domain-containing protein. (82 aa)
ENSUAMP00000000906TLE_N domain-containing protein. (130 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa)
AMIGO2Adhesion molecule with Ig like domain 2. (521 aa)
AXIN2Axin 2. (843 aa)
ENSUAMP00000001392Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (545 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (367 aa)
PKP4Plakophilin 4. (1148 aa)
LRP6LDL receptor related protein 6. (1431 aa)
ENSUAMP00000001958CS domain-containing protein. (97 aa)
ENSUAMP00000001991Uncharacterized protein. (53 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (563 aa)
LGR5Leucine rich repeat containing G protein-coupled receptor 5. (907 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
SENP2SUMO specific peptidase 2. (571 aa)
ENSUAMP00000002778E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (282 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (332 aa)
SNAPINSNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (270 aa)
SFRP1Secreted frizzled related protein 1. (337 aa)
ENSUAMP00000004203CS domain-containing protein. (109 aa)
ENSUAMP00000004313Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (64 aa)
ENSUAMP00000004444Uncharacterized protein. (100 aa)
ENSUAMP00000004535E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (282 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1166 aa)
WIF1WNT inhibitory factor 1. (354 aa)
ENSUAMP00000005084Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (385 aa)
PRICKLE1Prickle planar cell polarity protein 1. (832 aa)
ENSUAMP00000005842RING-type domain-containing protein. (787 aa)
ENSUAMP00000005976Uncharacterized protein. (94 aa)
ENSUAMP00000006331Uncharacterized protein. (514 aa)
ENSUAMP00000006334Uncharacterized protein. (254 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
CHD8Chromodomain helicase DNA binding protein 8. (1832 aa)
DVL3Dishevelled segment polarity protein 3. (716 aa)
ENSUAMP00000006884Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa)
ENSUAMP00000007617Protein kinase domain-containing protein. (271 aa)
RSPO4R-spondin 4. (229 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (651 aa)
TCF7Transcription factor 7. (443 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (150 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (299 aa)
ENSUAMP00000007849TLE_N domain-containing protein. (144 aa)
DAAM1Dishevelled associated activator of morphogenesis 1. (1078 aa)
LRRC24Leucine rich repeat containing 24. (515 aa)
PPP3CASerine/threonine-protein phosphatase. (317 aa)
NFATC4Nuclear factor of activated T cells 4. (911 aa)
TESTestin LIM domain protein. (421 aa)
RHOBRas homolog family member B. (172 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
ENSUAMP00000009120Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (436 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (468 aa)
MAPK8Mitogen-activated protein kinase. (456 aa)
ENSUAMP00000009333Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (91 aa)
ENSUAMP00000009335Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (134 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
PPP3CBSerine/threonine-protein phosphatase. (479 aa)
PRKCAProtein kinase C alpha; Belongs to the protein kinase superfamily. (484 aa)
RYKReceptor like tyrosine kinase. (599 aa)
PLCB1Phosphoinositide phospholipase C. (658 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
SFRP4Secreted frizzled related protein 4. (346 aa)
ENSUAMP00000011236Protein kinase domain-containing protein. (195 aa)
NFATC1Nuclear factor of activated T cells 1. (931 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (727 aa)
GSK3BGlycogen synthase kinase 3 beta. (335 aa)
ENSUAMP00000012266CTNNB1_binding domain-containing protein. (162 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (356 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa)
ENSUAMP00000012405Uncharacterized protein. (110 aa)
ENSUAMP00000012729RHD domain-containing protein. (481 aa)
SFRP5Secreted frizzled related protein 5. (316 aa)
ENSUAMP00000013482Uncharacterized protein. (91 aa)
ENSUAMP00000014208WD_REPEATS_REGION domain-containing protein. (574 aa)
ENSUAMP00000014210Uncharacterized protein. (379 aa)
CBY3Chibby family member 3. (215 aa)
CBY1Chibby family member 1, beta catenin antagonist. (127 aa)
ENSUAMP00000014717Uncharacterized protein. (131 aa)
C17orf64Chromosome 17 open reading frame 64. (226 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (971 aa)
ENSUAMP00000015431Uncharacterized protein. (297 aa)
ZNRF3Zinc and ring finger 3. (834 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
DVL1Dishevelled segment polarity protein 1. (700 aa)
ENSUAMP00000016536Uncharacterized protein. (119 aa)
EFEMP1EGF containing fibulin extracellular matrix protein 1. (459 aa)
PORCNPorcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family. (440 aa)
ENSUAMP00000016912Uncharacterized protein. (558 aa)
ELP3Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (524 aa)
DKK2Dickkopf WNT signaling pathway inhibitor 2. (259 aa)
CTNNB1Catenin beta 1. (781 aa)
INVSInversin. (694 aa)
RSPO1R-spondin 1. (263 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
TLE4TLE family member 4, transcriptional corepressor. (702 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
FHDC1FH2 domain containing 1. (1146 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
APC2APC regulator of WNT signaling pathway 2. (2266 aa)
DVL2Dishevelled segment polarity protein 2. (731 aa)
NKD2NKD inhibitor of WNT signaling pathway 2. (450 aa)
TBL1XR1Transducin beta like 1 X-linked receptor 1. (520 aa)
ENSUAMP00000019174CaMKII_AD domain-containing protein. (267 aa)
ENSUAMP00000019181Protein kinase domain-containing protein. (206 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1172 aa)
ENSUAMP00000019295Uncharacterized protein. (386 aa)
CTNNBIP1Catenin beta interacting protein 1. (70 aa)
RSPO2R-spondin 2. (220 aa)
DAND5DAN domain BMP antagonist family member 5. (190 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (657 aa)
SERPINF1Serpin family F member 1; Belongs to the serpin family. (418 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (589 aa)
AXIN1Axin 1. (867 aa)
ENSUAMP00000020051Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (445 aa)
ENSUAMP00000020288Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (296 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (714 aa)
NFATC3Nuclear factor of activated T cells 3. (1079 aa)
DKK4Dickkopf WNT signaling pathway inhibitor 4. (221 aa)
ENSUAMP00000020585Uncharacterized protein. (252 aa)
MMP7Matrix metallopeptidase 7. (292 aa)
FZD9Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (561 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (322 aa)
GPC4Glypican 4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (556 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
WDR92WD repeat domain 92. (357 aa)
ENSUAMP00000021954Uncharacterized protein. (209 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
ENSUAMP00000022336Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (163 aa)
ENSUAMP00000022339Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (107 aa)
MAPK10Mitogen-activated protein kinase. (422 aa)
SOSTSclerostin. (213 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa)
CCN4Cellular communication network factor 4. (361 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1384 aa)
FRZBFrizzled related protein. (298 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (344 aa)
CSNK1A1Casein kinase 1 alpha 1; Belongs to the protein kinase superfamily. (365 aa)
ENSUAMP00000025300Non-specific serine/threonine protein kinase. (254 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1606 aa)
PRICKLE2Prickle planar cell polarity protein 2. (896 aa)
TCF7L2Transcription factor 7 like 2. (524 aa)
LGR6Leucine rich repeat containing G protein-coupled receptor 6. (910 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (343 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (271 aa)
FIBPFGF1 intracellular binding protein. (357 aa)
EFEMP2EGF containing fibulin extracellular matrix protein 2. (443 aa)
CXXC4CXXC finger protein 4. (347 aa)
CTBP1C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (421 aa)
ENSUAMP00000027679Uncharacterized protein. (51 aa)
FZD10Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (595 aa)
VANGL2Vang-like protein. (492 aa)
ENSUAMP00000028248Helicase C-terminal domain-containing protein. (1149 aa)
ENSUAMP00000028314Uncharacterized protein. (386 aa)
VANGL1Vang-like protein. (519 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1136 aa)
MAPK9Mitogen-activated protein kinase. (433 aa)
CUL1Cullin 1; Belongs to the cullin family. (742 aa)
DAAM2Dishevelled associated activator of morphogenesis 2. (636 aa)
ENSUAMP00000029470Helicase C-terminal domain-containing protein. (1845 aa)
CER1Cerberus 1, DAN family BMP antagonist. (279 aa)
RAC1Rac family small GTPase 1. (229 aa)
CREBBPCREB binding protein. (2333 aa)
TLE3TLE family member 3, transcriptional corepressor. (787 aa)
RBX1Ring-box 1. (108 aa)
RAC2Rac family small GTPase 2. (192 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
CHD6Chromodomain helicase DNA binding protein 6. (2724 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa)
EP300E1A binding protein p300. (2399 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
NOTUMNotum, palmitoleoyl-protein carboxylesterase. (498 aa)
LRRC45Leucine rich repeat containing 45. (670 aa)
RAC3Rac family small GTPase 3. (202 aa)
FBXW11F-box and WD repeat domain containing 11. (543 aa)
NKD1NKD inhibitor of WNT signaling pathway 1. (447 aa)
ENSUAMP00000032382CaMKII_AD domain-containing protein. (189 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (294 aa)
PPP3CCSerine/threonine-protein phosphatase. (449 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
ARSIArylsulfatase family member I. (573 aa)
ENSUAMP00000033172Ig-like domain-containing protein. (211 aa)
ENSUAMP00000033173Kringle domain-containing protein. (90 aa)
ENSUAMP00000033199RHD domain-containing protein. (458 aa)
KCNK1Potassium two pore domain channel subfamily K member 1; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (331 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (361 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2987 aa)
ENSUAMP00000034574Uncharacterized protein. (525 aa)
ROR2Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (883 aa)
CXXC5CXXC finger protein 5. (318 aa)
ENSUAMP00000035281ULP_PROTEASE domain-containing protein. (102 aa)
RSPO3R-spondin 3. (275 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
SIAH2E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (325 aa)
CHD1Chromodomain helicase DNA binding protein 1. (1772 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
ENSUAMP00000035777HMG box domain-containing protein. (191 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (338 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa)
FZD1Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. (534 aa)
TCF7L1Transcription factor 7 like 1. (597 aa)
ENSUAMP00000036463TLE_N domain-containing protein. (120 aa)
SOX17SRY-box transcription factor 17. (406 aa)
CCND3Cyclin D3; Belongs to the cyclin family. (292 aa)
FRAT2FRAT regulator of WNT signaling pathway 2. (221 aa)
ENSUAMP00000037320Uncharacterized protein. (312 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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