STRINGSTRING
CSNK1G1 CSNK1G1 KIF7 KIF7 CUL1 CUL1 IHH IHH LRP4 LRP4 EVC2 EVC2 ENSUAMP00000027843 ENSUAMP00000027843 ENSUAMP00000027842 ENSUAMP00000027842 ENSUAMP00000027679 ENSUAMP00000027679 TSPAN33 TSPAN33 SMO SMO EVC EVC CSNK1A1 CSNK1A1 ARR3 ARR3 GLI1 GLI1 SMURF2 SMURF2 KIF27 KIF27 DHH DHH LMBR1L LMBR1L ATRN ATRN CSNK1G2 CSNK1G2 CSNK1G3 CSNK1G3 MGRN1 MGRN1 PTCH2 PTCH2 ENSUAMP00000023083 ENSUAMP00000023083 ARRB1 ARRB1 SPOP SPOP ENSUAMP00000024123 ENSUAMP00000024123 LRP2 LRP2 ENSUAMP00000005526 ENSUAMP00000005526 ENSUAMP00000005615 ENSUAMP00000005615 ARRB2 ARRB2 GRK2 GRK2 ENSUAMP00000006884 ENSUAMP00000006884 PTCH1 PTCH1 ENSUAMP00000009120 ENSUAMP00000009120 HHIP HHIP GPR161 GPR161 ENSUAMP00000010093 ENSUAMP00000010093 ATRNL1 ATRNL1 MOSMO MOSMO ENSUAMP00000011222 ENSUAMP00000011222 ENSUAMP00000011226 ENSUAMP00000011226 GRK3 GRK3 BCL2 BCL2 GSK3B GSK3B CDON CDON MEGF8 MEGF8 CSNK1D CSNK1D CUL3 CUL3 KIF3A KIF3A LMBR1 LMBR1 PRKACB PRKACB CCND1 CCND1 GLI3 GLI3 FBXW11 FBXW11 BTRC BTRC ENSUAMP00000030381 ENSUAMP00000030381 SPOPL SPOPL ENSUAMP00000030304 ENSUAMP00000030304
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CSNK1G1Casein kinase 1 gamma 1; Belongs to the protein kinase superfamily. (499 aa)
KIF7Kinesin family member 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1311 aa)
CUL1Cullin 1; Belongs to the cullin family. (742 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (419 aa)
LRP4LDL receptor related protein 4. (1852 aa)
EVC2EvC ciliary complex subunit 2. (992 aa)
ENSUAMP00000027843Uncharacterized protein. (119 aa)
ENSUAMP00000027842Uncharacterized protein. (99 aa)
ENSUAMP00000027679Uncharacterized protein. (51 aa)
TSPAN33Tetraspanin. (350 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (788 aa)
EVCEvC ciliary complex subunit 1. (976 aa)
CSNK1A1Casein kinase 1 alpha 1; Belongs to the protein kinase superfamily. (365 aa)
ARR3Arrestin 3. (380 aa)
GLI1GLI family zinc finger 1. (1105 aa)
SMURF2E3 ubiquitin-protein ligase. (736 aa)
KIF27Kinesin family member 27; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1401 aa)
DHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (396 aa)
LMBR1LLimb development membrane protein 1 like. (317 aa)
ATRNAttractin. (1419 aa)
CSNK1G2Casein kinase 1 gamma 2; Belongs to the protein kinase superfamily. (489 aa)
CSNK1G3Casein kinase 1 gamma 3; Belongs to the protein kinase superfamily. (435 aa)
MGRN1Mahogunin ring finger 1. (539 aa)
PTCH2Patched 2. (1207 aa)
ENSUAMP00000023083Uncharacterized protein. (485 aa)
ARRB1Arrestin beta 1. (380 aa)
SPOPSpeckle type BTB/POZ protein. (374 aa)
ENSUAMP00000024123Uncharacterized protein. (522 aa)
LRP2LDL receptor related protein 2. (4684 aa)
ENSUAMP00000005526Uncharacterized protein. (704 aa)
ENSUAMP00000005615Uncharacterized protein. (177 aa)
ARRB2Arrestin beta 2. (405 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (647 aa)
ENSUAMP00000006884Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa)
PTCH1Patched 1. (1453 aa)
ENSUAMP00000009120Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (436 aa)
HHIPHedgehog interacting protein. (508 aa)
GPR161G protein-coupled receptor 161. (413 aa)
ENSUAMP00000010093SUFU_C domain-containing protein. (81 aa)
ATRNL1Attractin like 1. (1188 aa)
MOSMOModulator of smoothened. (94 aa)
ENSUAMP00000011222Uncharacterized protein. (686 aa)
ENSUAMP00000011226Ig-like domain-containing protein. (152 aa)
GRK3G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (649 aa)
BCL2BCL2 apoptosis regulator. (205 aa)
GSK3BGlycogen synthase kinase 3 beta. (335 aa)
CDONCell adhesion associated, oncogene regulated. (1021 aa)
MEGF8Multiple EGF like domains 8. (2820 aa)
CSNK1DCasein kinase 1 delta; Belongs to the protein kinase superfamily. (428 aa)
CUL3Cullin 3; Belongs to the cullin family. (766 aa)
KIF3AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (684 aa)
LMBR1Limb development membrane protein 1; Belongs to the LIMR family. (490 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (361 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (294 aa)
GLI3GLI family zinc finger 3. (1413 aa)
FBXW11F-box and WD repeat domain containing 11. (543 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
ENSUAMP00000030381Uncharacterized protein. (67 aa)
SPOPLSpeckle type BTB/POZ protein like. (392 aa)
ENSUAMP00000030304HH_signal domain-containing protein. (146 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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