STRINGSTRING
CD22 CD22 ENSUAMP00000010596 ENSUAMP00000010596 AKT1 AKT1 ENSUAMP00000011223 ENSUAMP00000011223 NFATC1 NFATC1 ENSUAMP00000011509 ENSUAMP00000011509 ENSUAMP00000011552 ENSUAMP00000011552 ENSUAMP00000011661 ENSUAMP00000011661 AKT3 AKT3 ENSUAMP00000011858 ENSUAMP00000011858 GSK3B GSK3B GRB2 GRB2 ENSUAMP00000012729 ENSUAMP00000012729 ENSUAMP00000013482 ENSUAMP00000013482 MAPK1 MAPK1 ERAS ERAS NFKBIB NFKBIB IKBKG IKBKG SOS2 SOS2 ENSUAMP00000015993 ENSUAMP00000015993 ENSUAMP00000016793 ENSUAMP00000016793 ENSUAMP00000017435 ENSUAMP00000017435 ENSUAMP00000017692 ENSUAMP00000017692 ENSUAMP00000019309 ENSUAMP00000019309 PIK3CD PIK3CD CD19 CD19 NFATC3 NFATC3 IKBKB IKBKB KRAS KRAS NFKBIE NFKBIE NFKB1 NFKB1 IGHM IGHM ENSUAMP00000021954 ENSUAMP00000021954 ENSUAMP00000022131 ENSUAMP00000022131 BCL10 BCL10 BLNK BLNK RELA RELA ENSUAMP00000026993 ENSUAMP00000026993 BTK BTK ENSUAMP00000028152 ENSUAMP00000028152 ENSUAMP00000028178 ENSUAMP00000028178 ENSUAMP00000028179 ENSUAMP00000028179 ENSUAMP00000029031 ENSUAMP00000029031 ENSUAMP00000030280 ENSUAMP00000030280 MAP2K1 MAP2K1 RASGRP3 RASGRP3 NFKBIA NFKBIA RAC1 RAC1 RAF1 RAF1 ENSUAMP00000030787 ENSUAMP00000030787 RAC2 RAC2 CD81 CD81 ENSUAMP00000031486 ENSUAMP00000031486 VAV1 VAV1 MAPK3 MAPK3 CARD11 CARD11 ENSUAMP00000031719 ENSUAMP00000031719 SYK SYK RAC3 RAC3 ENSUAMP00000032511 ENSUAMP00000032511 PPP3CC PPP3CC SOS1 SOS1 CD72 CD72 ENSUAMP00000033199 ENSUAMP00000033199 ENSUAMP00000034569 ENSUAMP00000034569 ENSUAMP00000035331 ENSUAMP00000035331 PTPN6 PTPN6 ENSUAMP00000036324 ENSUAMP00000036324 INPPL1 INPPL1 INPP5D INPP5D CHUK CHUK AKT2 AKT2 PPP3CB PPP3CB ENSUAMP00000010013 ENSUAMP00000010013 VAV2 VAV2 PIK3CA PIK3CA JUN JUN CD79B CD79B CD79A CD79A PPP3CA PPP3CA PLCG2 PLCG2 PRKCB PRKCB ENSUAMP00000007314 ENSUAMP00000007314 ENSUAMP00000007032 ENSUAMP00000007032 ENSUAMP00000005057 ENSUAMP00000005057 DAPP1 DAPP1 ENSUAMP00000003693 ENSUAMP00000003693 ENSUAMP00000001254 ENSUAMP00000001254 CR2 CR2 ENSUAMP00000010475 ENSUAMP00000010475 PIK3R1 PIK3R1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CD22CD22 molecule. (842 aa)
ENSUAMP00000010596Ig-like domain-containing protein. (149 aa)
AKT1Non-specific serine/threonine protein kinase. (572 aa)
ENSUAMP00000011223Uncharacterized protein. (224 aa)
NFATC1Nuclear factor of activated T cells 1. (931 aa)
ENSUAMP00000011509Ig-like domain-containing protein. (352 aa)
ENSUAMP00000011552Ig-like domain-containing protein. (505 aa)
ENSUAMP00000011661Uncharacterized protein. (629 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
ENSUAMP00000011858Ig-like domain-containing protein. (518 aa)
GSK3BGlycogen synthase kinase 3 beta. (335 aa)
GRB2Growth factor receptor bound protein 2. (203 aa)
ENSUAMP00000012729RHD domain-containing protein. (481 aa)
ENSUAMP00000013482Uncharacterized protein. (91 aa)
MAPK1Mitogen-activated protein kinase. (364 aa)
ERASES cell expressed Ras. (219 aa)
NFKBIBNFKB inhibitor beta. (354 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (442 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1306 aa)
ENSUAMP00000015993Uncharacterized protein. (98 aa)
ENSUAMP00000016793BZIP domain-containing protein. (179 aa)
ENSUAMP00000017435Uncharacterized protein. (459 aa)
ENSUAMP00000017692Uncharacterized protein. (704 aa)
ENSUAMP00000019309Calponin-homology (CH) domain-containing protein. (82 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1041 aa)
CD19CD19 molecule. (554 aa)
NFATC3Nuclear factor of activated T cells 3. (1079 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (703 aa)
KRASKRAS proto-oncogene, GTPase. (188 aa)
NFKBIENFKB inhibitor epsilon. (362 aa)
NFKB1Nuclear factor kappa B subunit 1. (972 aa)
IGHMImmunoglobulin heavy constant mu. (480 aa)
ENSUAMP00000021954Uncharacterized protein. (209 aa)
ENSUAMP00000022131Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (636 aa)
BCL10BCL10 immune signaling adaptor. (234 aa)
BLNKB cell linker. (483 aa)
RELARELA proto-oncogene, NF-kB subunit. (508 aa)
ENSUAMP00000026993Uncharacterized protein. (118 aa)
BTKTyrosine-protein kinase. (663 aa)
ENSUAMP00000028152SH3 domain-containing protein. (120 aa)
ENSUAMP00000028178Uncharacterized protein. (311 aa)
ENSUAMP00000028179CSD domain-containing protein. (89 aa)
ENSUAMP00000029031Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa)
ENSUAMP00000030280Protein kinase domain-containing protein. (206 aa)
MAP2K1Protein kinase domain-containing protein. (216 aa)
RASGRP3RAS guanyl releasing protein 3. (663 aa)
NFKBIANFKB inhibitor alpha. (314 aa)
RAC1Rac family small GTPase 1. (229 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (564 aa)
ENSUAMP00000030787Uncharacterized protein. (84 aa)
RAC2Rac family small GTPase 2. (192 aa)
CD81Tetraspanin. (392 aa)
ENSUAMP00000031486Calponin-homology (CH) domain-containing protein. (86 aa)
VAV1Vav guanine nucleotide exchange factor 1. (774 aa)
MAPK3Mitogen-activated protein kinase. (354 aa)
CARD11Caspase recruitment domain family member 11. (1123 aa)
ENSUAMP00000031719Uncharacterized protein. (627 aa)
SYKSpleen associated tyrosine kinase. (638 aa)
RAC3Rac family small GTPase 3. (202 aa)
ENSUAMP00000032511Protein kinase domain-containing protein. (132 aa)
PPP3CCSerine/threonine-protein phosphatase. (449 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1232 aa)
CD72CD72 molecule. (345 aa)
ENSUAMP00000033199RHD domain-containing protein. (458 aa)
ENSUAMP00000034569Uncharacterized protein. (250 aa)
ENSUAMP00000035331Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (506 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
ENSUAMP00000036324Uncharacterized protein. (189 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1261 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1197 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PPP3CBSerine/threonine-protein phosphatase. (479 aa)
ENSUAMP00000010013Uncharacterized protein. (73 aa)
VAV2Vav guanine nucleotide exchange factor 2. (855 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
CD79BCD79b molecule. (299 aa)
CD79ACD79a molecule. (231 aa)
PPP3CASerine/threonine-protein phosphatase. (317 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1252 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (651 aa)
ENSUAMP00000007314Ig-like domain-containing protein. (624 aa)
ENSUAMP00000007032Uncharacterized protein. (505 aa)
ENSUAMP00000005057Uncharacterized protein. (445 aa)
DAPP1Dual adaptor of phosphotyrosine and 3-phosphoinositides 1. (280 aa)
ENSUAMP00000003693Uncharacterized protein. (166 aa)
ENSUAMP00000001254Uncharacterized protein. (96 aa)
CR2Complement C3d receptor 2. (1009 aa)
ENSUAMP00000010475IGv domain-containing protein. (144 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (676 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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