(31 nodes) Circadian rhythm network (Ursus americanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PRKAA1	Non-specific serine/threonine protein kinase. (559 aa)
	PRKAG1	Protein kinase AMP-activated non-catalytic subunit gamma 1. (330 aa)
	CRY1	Cryptochrome circadian regulator 1. (587 aa)
	ENSUAMP00000026643	Uncharacterized protein. (232 aa)
	FBXW11	F-box and WD repeat domain containing 11. (543 aa)
	BTRC	Beta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
	RBX1	Ring-box 1. (108 aa)
	ARNTL	Aryl hydrocarbon receptor nuclear translocator like. (626 aa)
	CUL1	Cullin 1; Belongs to the cullin family. (742 aa)
	PRKAB2	Protein kinase AMP-activated non-catalytic subunit beta 2. (286 aa)
	MYCBP2	MYC binding protein 2. (4749 aa)
	PRKAG3	Protein kinase AMP-activated non-catalytic subunit gamma 3. (491 aa)
	ENSUAMP00000027679	Uncharacterized protein. (51 aa)
	FBXL3	F-box and leucine rich repeat protein 3. (428 aa)
	PER1	Period circadian regulator 1. (1293 aa)
	ENSUAMP00000006139	BHLH domain-containing protein. (282 aa)
	SKP1	S-phase kinase associated protein 1; Belongs to the SKP1 family. (150 aa)
	NPAS2	Neuronal PAS domain protein 2. (822 aa)
	ENSUAMP00000009120	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (436 aa)
	CSNK1D	Casein kinase 1 delta; Belongs to the protein kinase superfamily. (428 aa)
	RORB	RAR related orphan receptor B. (502 aa)
	PRKAA2	Non-specific serine/threonine protein kinase. (525 aa)
	PER2	Period circadian regulator 2. (1267 aa)
	ENSUAMP00000016357	Uncharacterized protein. (330 aa)
	ENSUAMP00000017347	Uncharacterized protein. (64 aa)
	ENSUAMP00000017349	Uncharacterized protein. (125 aa)
	NR1D1	Nuclear receptor subfamily 1 group D member 1. (600 aa)
	RORC	RAR related orphan receptor C. (517 aa)
	CRY2	Cryptochrome circadian regulator 2. (604 aa)
	CREB1	cAMP responsive element binding protein 1. (341 aa)
	RORA	RAR related orphan receptor A. (522 aa)

Your Current Organism:

Ursus americanus

NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARNTL	BTRC	ENSUAMP00000029342	ENSUAMP00000031418	Aryl hydrocarbon receptor nuclear translocator like.	Beta-transducin repeat containing E3 ubiquitin protein ligase.	0.663
ARNTL	CRY1	ENSUAMP00000029342	ENSUAMP00000034692	Aryl hydrocarbon receptor nuclear translocator like.	Cryptochrome circadian regulator 1.	0.998
ARNTL	CRY2	ENSUAMP00000029342	ENSUAMP00000023985	Aryl hydrocarbon receptor nuclear translocator like.	Cryptochrome circadian regulator 2.	0.998
ARNTL	CSNK1D	ENSUAMP00000029342	ENSUAMP00000014472	Aryl hydrocarbon receptor nuclear translocator like.	Casein kinase 1 delta; Belongs to the protein kinase superfamily.	0.966
ARNTL	ENSUAMP00000006139	ENSUAMP00000029342	ENSUAMP00000006139	Aryl hydrocarbon receptor nuclear translocator like.	BHLH domain-containing protein.	0.544
ARNTL	ENSUAMP00000009120	ENSUAMP00000029342	ENSUAMP00000009120	Aryl hydrocarbon receptor nuclear translocator like.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.963
ARNTL	FBXL3	ENSUAMP00000029342	ENSUAMP00000026859	Aryl hydrocarbon receptor nuclear translocator like.	F-box and leucine rich repeat protein 3.	0.580
ARNTL	FBXW11	ENSUAMP00000029342	ENSUAMP00000032203	Aryl hydrocarbon receptor nuclear translocator like.	F-box and WD repeat domain containing 11.	0.560
ARNTL	NPAS2	ENSUAMP00000029342	ENSUAMP00000008036	Aryl hydrocarbon receptor nuclear translocator like.	Neuronal PAS domain protein 2.	0.997
ARNTL	NR1D1	ENSUAMP00000029342	ENSUAMP00000019321	Aryl hydrocarbon receptor nuclear translocator like.	Nuclear receptor subfamily 1 group D member 1.	0.678
ARNTL	PER1	ENSUAMP00000029342	ENSUAMP00000005992	Aryl hydrocarbon receptor nuclear translocator like.	Period circadian regulator 1.	0.974
ARNTL	PER2	ENSUAMP00000029342	ENSUAMP00000015883	Aryl hydrocarbon receptor nuclear translocator like.	Period circadian regulator 2.	0.984
ARNTL	RORA	ENSUAMP00000029342	ENSUAMP00000024509	Aryl hydrocarbon receptor nuclear translocator like.	RAR related orphan receptor A.	0.623
ARNTL	RORB	ENSUAMP00000029342	ENSUAMP00000014853	Aryl hydrocarbon receptor nuclear translocator like.	RAR related orphan receptor B.	0.566
ARNTL	RORC	ENSUAMP00000029342	ENSUAMP00000022890	Aryl hydrocarbon receptor nuclear translocator like.	RAR related orphan receptor C.	0.526
BTRC	ARNTL	ENSUAMP00000031418	ENSUAMP00000029342	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Aryl hydrocarbon receptor nuclear translocator like.	0.663
BTRC	CRY1	ENSUAMP00000031418	ENSUAMP00000034692	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Cryptochrome circadian regulator 1.	0.456
BTRC	CRY2	ENSUAMP00000031418	ENSUAMP00000023985	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Cryptochrome circadian regulator 2.	0.481
BTRC	CSNK1D	ENSUAMP00000031418	ENSUAMP00000014472	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Casein kinase 1 delta; Belongs to the protein kinase superfamily.	0.773
BTRC	CUL1	ENSUAMP00000031418	ENSUAMP00000028874	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Cullin 1; Belongs to the cullin family.	0.987