STRINGSTRING
ENSUAMP00000009201 ENSUAMP00000009201 ITGAM ITGAM PYCARD PYCARD ENSUAMP00000010491 ENSUAMP00000010491 ENSUAMP00000010907 ENSUAMP00000010907 IL12A IL12A ENSUAMP00000011448 ENSUAMP00000011448 NFKB2 NFKB2 HSF5 HSF5 CASP7 CASP7 ENSUAMP00000006947 ENSUAMP00000006947 ENSUAMP00000006948 ENSUAMP00000006948 CASP8 CASP8 ENSUAMP00000008737 ENSUAMP00000008737 ENSUAMP00000017060 ENSUAMP00000017060 ENSUAMP00000017057 ENSUAMP00000017057 ENSUAMP00000016311 ENSUAMP00000016311 BNIP3 BNIP3 OTUD3 OTUD3 ENSUAMP00000013303 ENSUAMP00000013303 CLK1 CLK1 ENSUAMP00000014053 ENSUAMP00000014053 ENSUAMP00000018161 ENSUAMP00000018161 RAB1A RAB1A HSF4 HSF4 CXCL8 CXCL8 CASP3 CASP3 IL12B IL12B TNF TNF HSF1 HSF1 ENSUAMP00000035946 ENSUAMP00000035946 EEF1G EEF1G CLK3 CLK3 GUF1 GUF1 ENSUAMP00000034888 ENSUAMP00000034888 ITGB2 ITGB2 ENSUAMP00000033303 ENSUAMP00000033303 EEF1A2 EEF1A2 IL1B IL1B TLR4 TLR4 ENSUAMP00000031983 ENSUAMP00000031983 ENSUAMP00000031906 ENSUAMP00000031906 VCP VCP C3 C3 IL6 IL6 ENSUAMP00000030825 ENSUAMP00000030825 ENSUAMP00000020607 ENSUAMP00000020607 ARF1 ARF1 NFKB1 NFKB1 TLR2 TLR2 SAR1B SAR1B CASP9 CASP9 IL18 IL18 NFKBIA NFKBIA METRNL METRNL ENSUAMP00000029349 ENSUAMP00000029349 C7orf31 C7orf31 CYCS CYCS ENSUAMP00000024050 ENSUAMP00000024050 HSF2 HSF2 HSPA8 HSPA8 TLR5 TLR5 RAB1B RAB1B RELA RELA CLK2 CLK2 HSPA2 HSPA2 APAF1 APAF1 CLK4 CLK4 ENSUAMP00000024175 ENSUAMP00000024175 ENSUAMP00000009010 ENSUAMP00000009010 MYD88 MYD88 ENSUAMP00000006128 ENSUAMP00000006128 ENSUAMP00000015745 ENSUAMP00000015745 ENSUAMP00000006398 ENSUAMP00000006398 ENSUAMP00000000439 ENSUAMP00000000439 HBS1L HBS1L ENSUAMP00000001165 ENSUAMP00000001165 ENSUAMP00000001501 ENSUAMP00000001501 ENSUAMP00000002214 ENSUAMP00000002214 ENSUAMP00000002216 ENSUAMP00000002216 ENSUAMP00000003236 ENSUAMP00000003236 SAR1A SAR1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSUAMP00000009201Tr-type G domain-containing protein. (429 aa)
ITGAMIntegrin subunit alpha M; Belongs to the integrin alpha chain family. (1208 aa)
PYCARDPYD and CARD domain containing. (194 aa)
ENSUAMP00000010491Uncharacterized protein; Belongs to the TCP-1 chaperonin family. (153 aa)
ENSUAMP00000010907Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (458 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (222 aa)
ENSUAMP00000011448Tr-type G domain-containing protein. (112 aa)
NFKB2Nuclear factor kappa B subunit 2. (581 aa)
HSF5Heat shock transcription factor 5. (501 aa)
CASP7Caspase 7; Belongs to the peptidase C14A family. (301 aa)
ENSUAMP00000006947Tr-type G domain-containing protein. (120 aa)
ENSUAMP00000006948Uncharacterized protein. (239 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (395 aa)
ENSUAMP00000008737Tr-type G domain-containing protein. (419 aa)
ENSUAMP00000017060C-X-C motif chemokine. (107 aa)
ENSUAMP00000017057C-X-C motif chemokine. (107 aa)
ENSUAMP00000016311Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (98 aa)
BNIP3BCL2 interacting protein 3. (263 aa)
OTUD3OTU deubiquitinase 3. (398 aa)
ENSUAMP00000013303Uncharacterized protein. (192 aa)
CLK1CDC like kinase 1; Belongs to the protein kinase superfamily. (484 aa)
ENSUAMP00000014053EF-hand domain-containing protein. (72 aa)
ENSUAMP00000018161HSF_DOMAIN domain-containing protein. (357 aa)
RAB1ARAB1A, member RAS oncogene family. (210 aa)
HSF4Heat shock transcription factor 4. (492 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (266 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (329 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (230 aa)
HSF1Heat shock transcription factor 1. (554 aa)
ENSUAMP00000035946Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (181 aa)
EEF1GEukaryotic translation elongation factor 1 gamma. (437 aa)
CLK3CDC like kinase 3. (634 aa)
GUF1Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. (669 aa)
ENSUAMP00000034888Tr-type G domain-containing protein. (75 aa)
ITGB2Integrin beta. (815 aa)
ENSUAMP00000033303Tr-type G domain-containing protein. (400 aa)
EEF1A2Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (463 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (833 aa)
ENSUAMP00000031983Uncharacterized protein; Belongs to the heat shock protein 70 family. (653 aa)
ENSUAMP00000031906Uncharacterized protein. (55 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
C3Complement C3. (1667 aa)
IL6Interleukin 6. (212 aa)
ENSUAMP00000030825HSF_DOMAIN domain-containing protein. (400 aa)
ENSUAMP00000020607Uncharacterized protein. (413 aa)
ARF1ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family. (181 aa)
NFKB1Nuclear factor kappa B subunit 1. (972 aa)
TLR2Toll like receptor 2; Belongs to the Toll-like receptor family. (787 aa)
SAR1BSecretion associated Ras related GTPase 1B; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (467 aa)
IL18Interleukin 18. (167 aa)
NFKBIANFKB inhibitor alpha. (314 aa)
METRNLMeteorin like, glial cell differentiation regulator. (311 aa)
ENSUAMP00000029349Tr-type G domain-containing protein. (151 aa)
C7orf31Chromosome 7 open reading frame 31. (575 aa)
CYCSCytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
ENSUAMP00000024050HSF_DOMAIN domain-containing protein. (417 aa)
HSF2Heat shock transcription factor 2. (519 aa)
HSPA8Uncharacterized protein; Belongs to the heat shock protein 70 family. (646 aa)
TLR5Toll like receptor 5; Belongs to the Toll-like receptor family. (883 aa)
RAB1BRAB1B, member RAS oncogene family. (201 aa)
RELARELA proto-oncogene, NF-kB subunit. (508 aa)
CLK2CDC like kinase 2; Belongs to the protein kinase superfamily. (500 aa)
HSPA2Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. (611 aa)
APAF1Apoptotic peptidase activating factor 1. (948 aa)
CLK4CDC like kinase 4; Belongs to the protein kinase superfamily. (458 aa)
ENSUAMP00000024175Tr-type G domain-containing protein. (114 aa)
ENSUAMP00000009010Tr-type G domain-containing protein. (98 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
ENSUAMP00000006128annotation not available (106 aa)
ENSUAMP00000015745Tr-type G domain-containing protein. (90 aa)
ENSUAMP00000006398annotation not available (356 aa)
ENSUAMP00000000439Uncharacterized protein. (456 aa)
HBS1LHBS1 like translational GTPase. (685 aa)
ENSUAMP00000001165Uncharacterized protein. (96 aa)
ENSUAMP00000001501Uncharacterized protein. (470 aa)
ENSUAMP00000002214Longin domain-containing protein. (62 aa)
ENSUAMP00000002216Uncharacterized protein; Belongs to the synaptobrevin family. (143 aa)
ENSUAMP00000003236C-X-C motif chemokine. (106 aa)
SAR1ASecretion associated Ras related GTPase 1A; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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