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| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa) |
| | MAPK3 | Mitogen-activated protein kinase. (354 aa) |
| | TRIM71 | Tripartite motif containing 71. (858 aa) |
| | ENSUAMP00000030830 | Uncharacterized protein. (290 aa) |
| | ENSUAMP00000030787 | Uncharacterized protein. (84 aa) |
| | CREBBP | CREB binding protein. (2333 aa) |
| | BMF | Bcl2 modifying factor. (184 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (564 aa) |
| | FSCN1 | Fascin. (431 aa) |
| | CDC25A | Cell division cycle 25A. (498 aa) |
| | DNMT3B | DNA methyltransferase 3 beta; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (862 aa) |
| | IGF2BP1 | Insulin like growth factor 2 mRNA binding protein 1. (577 aa) |
| | MAP2K1 | Protein kinase domain-containing protein. (216 aa) |
| | ENSUAMP00000030280 | Protein kinase domain-containing protein. (206 aa) |
| | BCL2L11 | BCL2 like 11. (140 aa) |
| | EZR | Ezrin. (586 aa) |
| | IRS2 | Insulin receptor substrate 2. (1089 aa) |
| | DICER1 | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. (1870 aa) |
| | ENSUAMP00000014875 | Uncharacterized protein. (837 aa) |
| | SERPINB5 | Serpin family B member 5; Belongs to the serpin family. (375 aa) |
| | CDCA5 | Cell division cycle associated 5. (253 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1306 aa) |
| | ENSUAMP00000015993 | Uncharacterized protein. (98 aa) |
| | ENSUAMP00000016067 | Uncharacterized protein. (590 aa) |
| | ENSUAMP00000016192 | Integrin beta; Belongs to the integrin beta chain family. (786 aa) |
| | ENSUAMP00000016504 | BRCT domain-containing protein. (101 aa) |
| | CRK | CRK proto-oncogene, adaptor protein. (204 aa) |
| | ENSUAMP00000016664 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (99 aa) |
| | UBE2I | Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (102 aa) |
| | ENSUAMP00000017435 | Uncharacterized protein. (459 aa) |
| | RPS6KA5 | Ribosomal protein S6 kinase. (798 aa) |
| | ENSUAMP00000017692 | Uncharacterized protein. (704 aa) |
| | ENSUAMP00000017705 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (246 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (479 aa) |
| | SHC1 | SHC adaptor protein 1. (474 aa) |
| | ADAM15 | ADAM metallopeptidase domain 15. (832 aa) |
| | MCL1 | MCL1 apoptosis regulator, BCL2 family member. (350 aa) |
| | APC2 | APC regulator of WNT signaling pathway 2. (2266 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa) |
| | ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1365 aa) |
| | CYP1B1 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa) |
| | PLAU | Plasminogen activator, urokinase; Belongs to the peptidase S1 family. (432 aa) |
| | ZFPM2 | Zinc finger protein, FOG family member 2. (1193 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2523 aa) |
| | PTGS2 | Prostaglandin-endoperoxide synthase 2. (604 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1041 aa) |
| | HMOX1 | Heme oxygenase 1. (288 aa) |
| | ENSUAMP00000001524 | Uncharacterized protein. (75 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (211 aa) |
| | ENSUAMP00000000161 | Uncharacterized protein. (78 aa) |
| | APC | APC regulator of WNT signaling pathway. (2832 aa) |
| | IRS1 | Insulin receptor substrate 1. (1237 aa) |
| | CEP152 | Centrosomal protein 152. (1716 aa) |
| | SOX12 | Transcription factor SOX. (314 aa) |
| | ZEB1 | Zinc finger E-box binding homeobox 1. (1017 aa) |
| | PAK4 | Non-specific serine/threonine protein kinase. (488 aa) |
| | ENSUAMP00000003258 | Uncharacterized protein. (246 aa) |
| | ENSUAMP00000003693 | Uncharacterized protein. (166 aa) |
| | ENSUAMP00000004316 | Ephrin RBD domain-containing protein; Belongs to the ephrin family. (216 aa) |
| | E2F2 | E2F transcription factor 2. (431 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa) |
| | ENSUAMP00000004964 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1696 aa) |
| | ENSUAMP00000005976 | Uncharacterized protein. (94 aa) |
| | ABCC1 | ATP binding cassette subfamily C member 1. (1415 aa) |
| | PIM1 | Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (392 aa) |
| | ENSUAMP00000006884 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa) |
| | RDX | Radixin. (583 aa) |
| | ENSUAMP00000007257 | Hist_deacetyl domain-containing protein. (252 aa) |
| | CDKN1B | Cyclin dependent kinase inhibitor 1B. (200 aa) |
| | ENSUAMP00000007696 | Fork-head domain-containing protein. (585 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (651 aa) |
| | TP63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1252 aa) |
| | CRKL | CRK like proto-oncogene, adaptor protein. (303 aa) |
| | DNMT1 | DNA methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (981 aa) |
| | CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | RHOB | Ras homolog family member B. (172 aa) |
| | MDM4 | Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (492 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | CCNE1 | Cyclin E1; Belongs to the cyclin family. (370 aa) |
| | ENSUAMP00000008823 | TAN domain-containing protein. (111 aa) |
| | PDGFA | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (248 aa) |
| | SPRY2 | Sprouty RTK signaling antagonist 2. (315 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (516 aa) |
| | MET | MET proto-oncogene, receptor tyrosine kinase. (1399 aa) |
| | SOX4 | Transcription factor SOX. (452 aa) |
| | ENSUAMP00000009491 | C2 tensin-type domain-containing protein. (179 aa) |
| | EFNA5 | Ephrin A5; Belongs to the ephrin family. (188 aa) |
| | ABL1 | Tyrosine-protein kinase. (1138 aa) |
| | ENSUAMP00000009775 | C2 domain-containing protein. (151 aa) |
| | ENSUAMP00000010013 | Uncharacterized protein. (73 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1256 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (676 aa) |
| | PRKCA | Protein kinase C alpha; Belongs to the protein kinase superfamily. (484 aa) |
| | FGFR3 | Fibroblast growth factor receptor. (691 aa) |
| | ENSUAMP00000011147 | Ion_trans domain-containing protein. (118 aa) |
| | DDIT4 | DNA damage inducible transcript 4. (231 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1261 aa) |
| | ENSUAMP00000011802 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1116 aa) |
| | BCL2 | BCL2 apoptosis regulator. (205 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (356 aa) |
| | ENSUAMP00000012405 | Uncharacterized protein. (110 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (203 aa) |
| | DNMT3A | DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (912 aa) |
| | ERBB3 | Erb-b2 receptor tyrosine kinase 3. (1281 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (364 aa) |
| | ERAS | ES cell expressed Ras. (219 aa) |
| | HDAC4 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (815 aa) |
| | RASSF1 | Ras association domain family member 1. (272 aa) |
| | ENSUAMP00000037288 | Uncharacterized protein. (95 aa) |
| | MMP16 | Matrix metallopeptidase 16. (607 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (857 aa) |
| | NOTCH3 | Notch receptor 3. (2291 aa) |
| | CCNG1 | Cyclin G1; Belongs to the cyclin family. (295 aa) |
| | ENSUAMP00000036324 | Uncharacterized protein. (189 aa) |
| | ENSUAMP00000036314 | Protein kinase domain-containing protein. (321 aa) |
| | ENSUAMP00000036162 | Protein kinase domain-containing protein. (462 aa) |
| | VIM | Vimentin; Belongs to the intermediate filament family. (447 aa) |
| | HDAC2 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (446 aa) |
| | TIMP3 | TIMP metallopeptidase inhibitor 3. (211 aa) |
| | WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (338 aa) |
| | HNRNPK | Heterogeneous nuclear ribonucleoprotein K. (464 aa) |
| | ENSUAMP00000035681 | Protein kinase domain-containing protein. (217 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (714 aa) |
| | NOTCH4 | Notch receptor 4. (1894 aa) |
| | GPSM3 | G protein signaling modulator 3. (157 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (703 aa) |
| | CASP3 | Caspase 3; Belongs to the peptidase C14A family. (266 aa) |
| | ENSUAMP00000020648 | Uncharacterized protein. (1574 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (439 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (188 aa) |
| | CYP24A1 | Cytochrome P450 family 24 subfamily A member 1; Belongs to the cytochrome P450 family. (516 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (972 aa) |
| | SIRT1 | Sirtuin 1. (618 aa) |
| | FSCN2 | Fascin actin-bundling protein 2, retinal. (535 aa) |
| | TNN | Tenascin N. (1408 aa) |
| | THBS1 | Thrombospondin 1. (1170 aa) |
| | FZD3 | Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa) |
| | ENSUAMP00000022131 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (636 aa) |
| | SLC7A1 | Solute carrier family 7 member 1. (592 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (495 aa) |
| | ENSUAMP00000025300 | Non-specific serine/threonine protein kinase. (254 aa) |
| | ENSUAMP00000025354 | HMG box domain-containing protein. (302 aa) |
| | ENSUAMP00000025721 | Uncharacterized protein. (113 aa) |
| | ENSUAMP00000026413 | ETS domain-containing protein. (843 aa) |
| | EFNA1 | Ephrin A1; Belongs to the ephrin family. (205 aa) |
| | ENSUAMP00000026789 | Ephrin RBD domain-containing protein; Belongs to the ephrin family. (221 aa) |
| | SOCS1 | Suppressor of cytokine signaling 1. (214 aa) |
| | ENSUAMP00000026993 | Uncharacterized protein. (118 aa) |
| | ENSUAMP00000027431 | Uncharacterized protein. (74 aa) |
| | ENSUAMP00000027942 | Link domain-containing protein. (477 aa) |
| | GLS2 | Glutaminase 2. (602 aa) |
| | IGF2BP3 | Uncharacterized protein. (487 aa) |
| | ENSUAMP00000028178 | Uncharacterized protein. (311 aa) |
| | ENSUAMP00000028179 | CSD domain-containing protein. (89 aa) |
| | ENSUAMP00000028265 | RING-type domain-containing protein. (357 aa) |
| | ITGA5 | Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1067 aa) |
| | TPM1 | Tropomyosin 1; Belongs to the tropomyosin family. (284 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) |
| | MMP9 | Matrix metallopeptidase 9. (704 aa) |
| | EZH2 | Enhancer of zeste 2 polycomb repressive complex 2 subunit. (746 aa) |
| | ENSUAMP00000029031 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa) |
| | TNXB | Tenascin XB. (469 aa) |
| | CDC25B | Cell division cycle 25B. (559 aa) |
| | ZEB2 | Zinc finger E-box binding homeobox 2. (1214 aa) |
| | ENSUAMP00000035331 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (506 aa) |
| | KIF23 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (955 aa) |
| | ENSUAMP00000034736 | HDAC4_Gln domain-containing protein. (230 aa) |
| | RECK | Reversion inducing cysteine rich protein with kazal motifs. (971 aa) |
| | E2F3 | E2F transcription factor 3. (469 aa) |
| | E2F1 | E2F transcription factor 1. (400 aa) |
| | ENSUAMP00000034435 | EF-hand_14 domain-containing protein. (259 aa) |
| | ENSUAMP00000034433 | Uncharacterized protein. (103 aa) |
| | ENSUAMP00000034431 | ANK_REP_REGION domain-containing protein. (93 aa) |
| | TNC | Tenascin C. (2201 aa) |
| | NOTCH1 | Notch receptor 1. (2547 aa) |
| | NOTCH2 | Notch receptor 2. (2374 aa) |
| | STMN1 | Stathmin; Belongs to the stathmin family. (149 aa) |
| | HOXD10 | Homeobox D10. (410 aa) |
| | ENSUAMP00000032923 | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (387 aa) |
| | ENSUAMP00000032909 | Uncharacterized protein. (592 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1232 aa) |
| | PDCD4 | Programmed cell death 4. (474 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (294 aa) |
| | ENSUAMP00000032511 | Protein kinase domain-containing protein. (132 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1100 aa) |
| | ENSUAMP00000032102 | RRM domain-containing protein. (79 aa) |
| | BCL2L2 | BCL2 like 2. (193 aa) |
| | EP300 | E1A binding protein p300. (2399 aa) |
| | ENSUAMP00000031719 | Uncharacterized protein. (627 aa) |
