STRINGSTRING
ENSUAMP00000035925 ENSUAMP00000035925 C8B C8B ENSUAMP00000014195 ENSUAMP00000014195 ENSUAMP00000014212 ENSUAMP00000014212 ENSUAMP00000014243 ENSUAMP00000014243 ENSUAMP00000014255 ENSUAMP00000014255 H1-3 H1-3 ENSUAMP00000014264 ENSUAMP00000014264 ENSUAMP00000014288 ENSUAMP00000014288 ENSUAMP00000014302 ENSUAMP00000014302 ENSUAMP00000014588 ENSUAMP00000014588 ENSUAMP00000014590 ENSUAMP00000014590 ENSUAMP00000014720 ENSUAMP00000014720 TRBV16 TRBV16 ENSUAMP00000014737 ENSUAMP00000014737 CD40 CD40 TNF TNF ENSUAMP00000015817 ENSUAMP00000015817 ENSUAMP00000015819 ENSUAMP00000015819 TRBV28 TRBV28 ENSUAMP00000016042 ENSUAMP00000016042 ENSUAMP00000016547 ENSUAMP00000016547 HLA-DOB HLA-DOB CD40LG CD40LG RO60 RO60 SNRPD1 SNRPD1 ENSUAMP00000017069 ENSUAMP00000017069 HIST3H2BB HIST3H2BB H2AW H2AW MACROH2A1 MACROH2A1 TRIM11 TRIM11 HLA-DRA HLA-DRA H2AX H2AX H1-4 H1-4 H2AC6 H2AC6 ENSUAMP00000020808 ENSUAMP00000020808 H1-6 H1-6 ENSUAMP00000020826 ENSUAMP00000020826 H1-1 H1-1 ENSUAMP00000020853 ENSUAMP00000020853 ENSUAMP00000020862 ENSUAMP00000020862 IGHM IGHM GRIN2A GRIN2A ENSUAMP00000022269 ENSUAMP00000022269 ENSUAMP00000022270 ENSUAMP00000022270 C6 C6 MROH2B MROH2B C7 C7 ENSUAMP00000023856 ENSUAMP00000023856 ENSUAMP00000023925 ENSUAMP00000023925 H3-3A H3-3A C1QB C1QB ENSUAMP00000037283 ENSUAMP00000037283 SSB SSB SNRPD3 SNRPD3 ENSUAMP00000035427 ENSUAMP00000035427 HLA-DOA HLA-DOA GRIN2B GRIN2B ENSUAMP00000033949 ENSUAMP00000033949 ENSUAMP00000033947 ENSUAMP00000033947 ENSUAMP00000033945 ENSUAMP00000033945 ENSUAMP00000033942 ENSUAMP00000033942 ENSUAMP00000033920 ENSUAMP00000033920 ENSUAMP00000033919 ENSUAMP00000033919 ENSUAMP00000033915 ENSUAMP00000033915 H2BC11 H2BC11 ENSUAMP00000032224 ENSUAMP00000032224 ENSUAMP00000032223 ENSUAMP00000032223 C2 C2 ENSUAMP00000031594 ENSUAMP00000031594 C3 C3 ENSUAMP00000031302 ENSUAMP00000031302 C1RL C1RL C1R C1R C1S C1S ENSUAMP00000029966 ENSUAMP00000029966 H2BE1 H2BE1 ENSUAMP00000029518 ENSUAMP00000029518 ENSUAMP00000029280 ENSUAMP00000029280 H2BC18 H2BC18 ENSUAMP00000029196 ENSUAMP00000029196 ENSUAMP00000029194 ENSUAMP00000029194 ENSUAMP00000029193 ENSUAMP00000029193 ENSUAMP00000029191 ENSUAMP00000029191 ENSUAMP00000029186 ENSUAMP00000029186 H2AC21 H2AC21 ENSUAMP00000029147 ENSUAMP00000029147 CD28 CD28 ACTN4 ACTN4 ENSUAMP00000026961 ENSUAMP00000026961 C1QA C1QA C1QC C1QC ENSUAMP00000003525 ENSUAMP00000003525 H2AJ H2AJ ENSUAMP00000003497 ENSUAMP00000003497 ENSUAMP00000003263 ENSUAMP00000003263 ENSUAMP00000003162 ENSUAMP00000003162 ENSUAMP00000002874 ENSUAMP00000002874 TRIM58 TRIM58 ENSUAMP00000002618 ENSUAMP00000002618 C8G C8G ENSUAMP00000001254 ENSUAMP00000001254 ENSUAMP00000000623 ENSUAMP00000000623 IL10 IL10 TRIM21 TRIM21 C8A C8A H1-5 H1-5 ENSUAMP00000006323 ENSUAMP00000006323 ENSUAMP00000006129 ENSUAMP00000006129 C5 C5 H2BC1 H2BC1 MACROH2A2 MACROH2A2 ENSUAMP00000006330 ENSUAMP00000006330 H2AZ1 H2AZ1 H3F3B H3F3B ENSUAMP00000006335 ENSUAMP00000006335 ELANE ELANE ENSUAMP00000006561 ENSUAMP00000006561 ENSUAMP00000006568 ENSUAMP00000006568 SNRPB SNRPB ENSUAMP00000006865 ENSUAMP00000006865 ENSUAMP00000006872 ENSUAMP00000006872 ENSUAMP00000007032 ENSUAMP00000007032 ENSUAMP00000007225 ENSUAMP00000007225 CTSG CTSG ENSUAMP00000010475 ENSUAMP00000010475 ENSUAMP00000010738 ENSUAMP00000010738 ENSUAMP00000011260 ENSUAMP00000011260 CD80 CD80 HLA-DMA HLA-DMA ENSUAMP00000012503 ENSUAMP00000012503 ACTN1 ACTN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSUAMP00000035925Ig-like domain-containing protein. (236 aa)
C8BComplement C8 beta chain. (526 aa)
ENSUAMP00000014195annotation not available (130 aa)
ENSUAMP00000014212annotation not available (126 aa)
ENSUAMP00000014243Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSUAMP00000014255Histone H2A; Belongs to the histone H2A family. (130 aa)
H1-3Histone cluster 1 H1 family member d. (221 aa)
ENSUAMP00000014264annotation not available (136 aa)
ENSUAMP00000014288Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSUAMP00000014302Histone H2A; Belongs to the histone H2A family. (141 aa)
ENSUAMP00000014588IGv domain-containing protein. (107 aa)
ENSUAMP00000014590Ig-like domain-containing protein. (148 aa)
ENSUAMP00000014720Ig-like domain-containing protein. (177 aa)
TRBV16T cell receptor beta variable 16 (gene/pseudogene). (127 aa)
ENSUAMP00000014737Uncharacterized protein. (242 aa)
CD40CD40 molecule. (265 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (230 aa)
ENSUAMP00000015817Ig-like domain-containing protein. (126 aa)
ENSUAMP00000015819Ig-like domain-containing protein. (141 aa)
TRBV28T cell receptor beta variable 28. (113 aa)
ENSUAMP00000016042Ig-like domain-containing protein. (387 aa)
ENSUAMP00000016547MHC_II_beta domain-containing protein. (275 aa)
HLA-DOBMajor histocompatibility complex, class II, DO beta. (261 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (249 aa)
RO60Ro60, Y RNA binding protein. (538 aa)
SNRPD1Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (117 aa)
ENSUAMP00000017069Histone H2B; Belongs to the histone H2B family. (126 aa)
HIST3H2BBHistone H2B; Belongs to the histone H2B family. (126 aa)
H2AWHistone H2A; Belongs to the histone H2A family. (130 aa)
MACROH2A1Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (371 aa)
TRIM11Tripartite motif containing 11. (468 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa)
H2AXHistone H2A; Belongs to the histone H2A family. (143 aa)
H1-4Histone cluster 1 H1 family member e. (238 aa)
H2AC6Histone H2A; Belongs to the histone H2A family. (130 aa)
ENSUAMP00000020808annotation not available (126 aa)
H1-6Histone cluster 1 H1 family member t. (209 aa)
ENSUAMP00000020826Ig-like domain-containing protein. (196 aa)
H1-1Histone cluster 1 H1 family member a. (212 aa)
ENSUAMP00000020853Histone domain-containing protein. (178 aa)
ENSUAMP00000020862H15 domain-containing protein. (216 aa)
IGHMImmunoglobulin heavy constant mu. (480 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1427 aa)
ENSUAMP00000022269Histone H2A; Belongs to the histone H2A family. (132 aa)
ENSUAMP00000022270Histone H2B; Belongs to the histone H2B family. (127 aa)
C6Complement C6. (739 aa)
MROH2BMaestro heat like repeat family member 2B. (1575 aa)
C7Complement C7. (755 aa)
ENSUAMP00000023856Uncharacterized protein. (1660 aa)
ENSUAMP00000023925Ig-like domain-containing protein. (180 aa)
H3-3AHistone domain-containing protein. (142 aa)
C1QBComplement C1q B chain. (249 aa)
ENSUAMP00000037283Ig-like domain-containing protein. (145 aa)
SSBSmall RNA binding exonuclease protection factor La. (380 aa)
SNRPD3Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (126 aa)
ENSUAMP00000035427Ig-like domain-containing protein; Belongs to the MHC class II family. (241 aa)
HLA-DOAMajor histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (283 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
ENSUAMP00000033949annotation not available (126 aa)
ENSUAMP00000033947Histone H2A; Belongs to the histone H2A family. (136 aa)
ENSUAMP00000033945Histone H3; Belongs to the histone H3 family. (93 aa)
ENSUAMP00000033942annotation not available (130 aa)
ENSUAMP00000033920annotation not available (128 aa)
ENSUAMP00000033919Histone domain-containing protein; Belongs to the histone H2B family. (128 aa)
ENSUAMP00000033915Histone domain-containing protein. (125 aa)
H2BC11Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSUAMP00000032224Histone H2A; Belongs to the histone H2A family. (112 aa)
ENSUAMP00000032223Uncharacterized protein. (113 aa)
C2Complement C2; Belongs to the peptidase S1 family. (743 aa)
ENSUAMP00000031594Uncharacterized protein. (1748 aa)
C3Complement C3. (1667 aa)
ENSUAMP00000031302Histone domain-containing protein; Belongs to the histone H2B family. (170 aa)
C1RLComplement C1r subcomponent like; Belongs to the peptidase S1 family. (538 aa)
C1RComplement C1r; Belongs to the peptidase S1 family. (713 aa)
C1SComplement C1s; Belongs to the peptidase S1 family. (695 aa)
ENSUAMP00000029966annotation not available (113 aa)
H2BE1Histone H2B; Belongs to the histone H2B family. (122 aa)
ENSUAMP00000029518Uncharacterized protein. (624 aa)
ENSUAMP00000029280DUF1968 domain-containing protein. (198 aa)
H2BC18Histone H2B; Belongs to the histone H2B family. (166 aa)
ENSUAMP00000029196Histone H3; Belongs to the histone H3 family. (136 aa)
ENSUAMP00000029194Histone H2A; Belongs to the histone H2A family. (130 aa)
ENSUAMP00000029193annotation not available (126 aa)
ENSUAMP00000029191Histone H2B; Belongs to the histone H2B family. (135 aa)
ENSUAMP00000029186Histone H2A; Belongs to the histone H2A family. (142 aa)
H2AC21Histone H2A; Belongs to the histone H2A family. (130 aa)
ENSUAMP00000029147Histone H2A; Belongs to the histone H2A family. (128 aa)
CD28CD28 molecule. (216 aa)
ACTN4Actinin alpha 4. (970 aa)
ENSUAMP00000026961Uncharacterized protein. (113 aa)
C1QAComplement C1q A chain. (245 aa)
C1QCComplement C1q C chain. (245 aa)
ENSUAMP00000003525Ig-like domain-containing protein; Belongs to the MHC class II family. (205 aa)
H2AJHistone H2A; Belongs to the histone H2A family. (129 aa)
ENSUAMP00000003497Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
ENSUAMP00000003263Ig-like domain-containing protein. (160 aa)
ENSUAMP00000003162Ig-like domain-containing protein. (206 aa)
ENSUAMP00000002874Ig-like domain-containing protein. (122 aa)
TRIM58Tripartite motif containing 58. (488 aa)
ENSUAMP00000002618Histone H2A; Belongs to the histone H2A family. (113 aa)
C8GComplement C8 gamma chain; Belongs to the calycin superfamily. Lipocalin family. (317 aa)
ENSUAMP00000001254Uncharacterized protein. (96 aa)
ENSUAMP00000000623Uncharacterized protein. (86 aa)
IL10Interleukin 10. (178 aa)
TRIM21Tripartite motif containing 21. (469 aa)
C8AComplement C8 alpha chain. (589 aa)
H1-5Histone cluster 1 H1 family member b. (226 aa)
ENSUAMP00000006323Histone H3; Belongs to the histone H3 family. (136 aa)
ENSUAMP00000006129Histone domain-containing protein. (199 aa)
C5Complement C5. (1694 aa)
H2BC1Histone H2B; Belongs to the histone H2B family. (127 aa)
MACROH2A2H2A histone family member Y2; Belongs to the histone H2A family. (392 aa)
ENSUAMP00000006330Histone H2A; Belongs to the histone H2A family. (130 aa)
H2AZ1Histone H2A; Belongs to the histone H2A family. (159 aa)
H3F3BHistone H3; Belongs to the histone H3 family. (136 aa)
ENSUAMP00000006335Histone H2B; Belongs to the histone H2B family. (135 aa)
ELANEElastase, neutrophil expressed; Belongs to the peptidase S1 family. (264 aa)
ENSUAMP00000006561Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSUAMP00000006568annotation not available (130 aa)
SNRPBSmall nuclear ribonucleoprotein-associated protein. (214 aa)
ENSUAMP00000006865MHC_II_beta domain-containing protein. (274 aa)
ENSUAMP00000006872MHC_II_beta domain-containing protein. (218 aa)
ENSUAMP00000007032Uncharacterized protein. (505 aa)
ENSUAMP00000007225Histone domain-containing protein; Belongs to the histone H2B family. (122 aa)
CTSGCathepsin G; Belongs to the peptidase S1 family. (285 aa)
ENSUAMP00000010475IGv domain-containing protein. (144 aa)
ENSUAMP00000010738Uncharacterized protein. (181 aa)
ENSUAMP00000011260DUF1968 domain-containing protein. (153 aa)
CD80CD80 molecule. (283 aa)
HLA-DMAMajor histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (261 aa)
ENSUAMP00000012503Ig-like domain-containing protein. (263 aa)
ACTN1Actinin alpha 1. (914 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.