STRINGSTRING
ENSUAMP00000015817 ENSUAMP00000015817 IL1A IL1A IL1B IL1B IL6 IL6 IL2 IL2 ENSUAMP00000029280 ENSUAMP00000029280 CD28 CD28 ENSUAMP00000023925 ENSUAMP00000023925 ENSUAMP00000023352 ENSUAMP00000023352 ENSUAMP00000023351 ENSUAMP00000023351 ENSUAMP00000023350 ENSUAMP00000023350 ENSUAMP00000022738 ENSUAMP00000022738 PRF1 PRF1 ENSUAMP00000020826 ENSUAMP00000020826 ENSUAMP00000020061 ENSUAMP00000020061 HLA-DRA HLA-DRA ENSUAMP00000018082 ENSUAMP00000018082 HLA-DOB HLA-DOB ENSUAMP00000016547 ENSUAMP00000016547 ENSUAMP00000016352 ENSUAMP00000016352 ENSUAMP00000016042 ENSUAMP00000016042 TRBV28 TRBV28 ENSUAMP00000015819 ENSUAMP00000015819 HLA-DOA HLA-DOA TNF TNF TRBV16 TRBV16 ENSUAMP00000014720 ENSUAMP00000014720 ENSUAMP00000014590 ENSUAMP00000014590 ENSUAMP00000014588 ENSUAMP00000014588 ENSUAMP00000012503 ENSUAMP00000012503 HLA-DMA HLA-DMA CD80 CD80 ENSUAMP00000011260 ENSUAMP00000011260 KLRG1 KLRG1 ENSUAMP00000009584 ENSUAMP00000009584 ENSUAMP00000006971 ENSUAMP00000006971 GZMB GZMB ENSUAMP00000006872 ENSUAMP00000006872 ENSUAMP00000000885 ENSUAMP00000000885 ENSUAMP00000000976 ENSUAMP00000000976 ENSUAMP00000002874 ENSUAMP00000002874 ENSUAMP00000003162 ENSUAMP00000003162 ENSUAMP00000003263 ENSUAMP00000003263 ENSUAMP00000003525 ENSUAMP00000003525 ENSUAMP00000004899 ENSUAMP00000004899 ENSUAMP00000005117 ENSUAMP00000005117 ENSUAMP00000005351 ENSUAMP00000005351 ENSUAMP00000005465 ENSUAMP00000005465 ENSUAMP00000006240 ENSUAMP00000006240 ENSUAMP00000006865 ENSUAMP00000006865 ENSUAMP00000037283 ENSUAMP00000037283 ENSUAMP00000036887 ENSUAMP00000036887 ENSUAMP00000036043 ENSUAMP00000036043 ENSUAMP00000036029 ENSUAMP00000036029 ENSUAMP00000035925 ENSUAMP00000035925 ENSUAMP00000035427 ENSUAMP00000035427
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSUAMP00000015817Ig-like domain-containing protein. (126 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (244 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
IL6Interleukin 6. (212 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (155 aa)
ENSUAMP00000029280DUF1968 domain-containing protein. (198 aa)
CD28CD28 molecule. (216 aa)
ENSUAMP00000023925Ig-like domain-containing protein. (180 aa)
ENSUAMP00000023352Uncharacterized protein. (251 aa)
ENSUAMP00000023351Uncharacterized protein. (151 aa)
ENSUAMP00000023350Uncharacterized protein. (152 aa)
ENSUAMP00000022738Uncharacterized protein. (126 aa)
PRF1Perforin 1. (555 aa)
ENSUAMP00000020826Ig-like domain-containing protein. (196 aa)
ENSUAMP00000020061Ig-like domain-containing protein; Belongs to the MHC class I family. (332 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa)
ENSUAMP00000018082Uncharacterized protein. (249 aa)
HLA-DOBMajor histocompatibility complex, class II, DO beta. (261 aa)
ENSUAMP00000016547MHC_II_beta domain-containing protein. (275 aa)
ENSUAMP00000016352Ig-like domain-containing protein; Belongs to the MHC class I family. (358 aa)
ENSUAMP00000016042Ig-like domain-containing protein. (387 aa)
TRBV28T cell receptor beta variable 28. (113 aa)
ENSUAMP00000015819Ig-like domain-containing protein. (141 aa)
HLA-DOAMajor histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (283 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (230 aa)
TRBV16T cell receptor beta variable 16 (gene/pseudogene). (127 aa)
ENSUAMP00000014720Ig-like domain-containing protein. (177 aa)
ENSUAMP00000014590Ig-like domain-containing protein. (148 aa)
ENSUAMP00000014588IGv domain-containing protein. (107 aa)
ENSUAMP00000012503Ig-like domain-containing protein. (263 aa)
HLA-DMAMajor histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (261 aa)
CD80CD80 molecule. (283 aa)
ENSUAMP00000011260DUF1968 domain-containing protein. (153 aa)
KLRG1Killer cell lectin like receptor G1. (191 aa)
ENSUAMP00000009584Ig-like domain-containing protein; Belongs to the MHC class I family. (336 aa)
ENSUAMP00000006971Peptidase S1 domain-containing protein. (238 aa)
GZMBGranzyme B; Belongs to the peptidase S1 family. (260 aa)
ENSUAMP00000006872MHC_II_beta domain-containing protein. (218 aa)
ENSUAMP00000000885Uncharacterized protein. (67 aa)
ENSUAMP00000000976Ig-like domain-containing protein; Belongs to the MHC class I family. (481 aa)
ENSUAMP00000002874Ig-like domain-containing protein. (122 aa)
ENSUAMP00000003162Ig-like domain-containing protein. (206 aa)
ENSUAMP00000003263Ig-like domain-containing protein. (160 aa)
ENSUAMP00000003525Ig-like domain-containing protein; Belongs to the MHC class II family. (205 aa)
ENSUAMP00000004899Uncharacterized protein. (240 aa)
ENSUAMP00000005117Ig-like domain-containing protein. (412 aa)
ENSUAMP00000005351Uncharacterized protein. (94 aa)
ENSUAMP00000005465Ig-like domain-containing protein; Belongs to the MHC class I family. (431 aa)
ENSUAMP00000006240Ig-like domain-containing protein; Belongs to the MHC class I family. (359 aa)
ENSUAMP00000006865MHC_II_beta domain-containing protein. (274 aa)
ENSUAMP00000037283Ig-like domain-containing protein. (145 aa)
ENSUAMP00000036887Ig-like domain-containing protein. (179 aa)
ENSUAMP00000036043MHC_I-like_Ag-recog domain-containing protein. (150 aa)
ENSUAMP00000036029Ig-like domain-containing protein; Belongs to the MHC class I family. (359 aa)
ENSUAMP00000035925Ig-like domain-containing protein. (236 aa)
ENSUAMP00000035427Ig-like domain-containing protein; Belongs to the MHC class II family. (241 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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