21 items (Ailuropoda melanoleuca) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

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co-expression

protein homology

Your Input:
	HCN1	Hyperpolarization activated cyclic nucleotide gated potassium channel 1. (796 aa)
	GATA4	GATA binding protein 4. (448 aa)
	PKIA	cAMP-dependent protein kinase inhibitor; Belongs to the PKI family. (76 aa)
	RPL3L	Ribosomal protein L3 like; Belongs to the universal ribosomal protein uL3 family. (407 aa)
	TNNC1	Troponin C type 1 slow. (161 aa)
	AGT	Angiotensinogen; Belongs to the serpin family. (484 aa)
	NPPA	Natriuretic peptide A. (145 aa)
	NKX2-5	NK2 homeobox 5. (313 aa)
	S100A1	Protein S100; Belongs to the S-100 family. (103 aa)
	HMOX2	Heme oxygenase 2. (316 aa)
	TRIM55	Tripartite motif containing 55. (545 aa)
	KCNA7	Potassium voltage-gated channel subfamily A member 7; Belongs to the potassium channel family. (373 aa)
	PLA2G4F	Phospholipase A2. (858 aa)
	KCNK7	Potassium two pore domain channel subfamily K member 7; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (301 aa)
	GJA1	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa)
	GJA5	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
	HCN2	Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (701 aa)
	RYR2	Ryanodine receptor 2. (4911 aa)
	S100A11	Protein S100; Belongs to the S-100 family. (103 aa)
	TBX5	T-box transcription factor 5. (517 aa)
	INS-IGF2	INS-IGF2 readthrough; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (212 aa)

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGT	NPPA	ENSAMEP00000010215	ENSAMEP00000010367	Angiotensinogen; Belongs to the serpin family.	Natriuretic peptide A.	0.633
GATA4	GJA1	ENSAMEP00000006528	ENSAMEP00000020751	GATA binding protein 4.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.515
GATA4	INS-IGF2	ENSAMEP00000006528	ENSAMEP00000002279	GATA binding protein 4.	INS-IGF2 readthrough; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.435
GATA4	NKX2-5	ENSAMEP00000006528	ENSAMEP00000011903	GATA binding protein 4.	NK2 homeobox 5.	0.924
GATA4	NPPA	ENSAMEP00000006528	ENSAMEP00000010367	GATA binding protein 4.	Natriuretic peptide A.	0.601
GATA4	RYR2	ENSAMEP00000006528	ENSAMEP00000003073	GATA binding protein 4.	Ryanodine receptor 2.	0.437
GATA4	TBX5	ENSAMEP00000006528	ENSAMEP00000001182	GATA binding protein 4.	T-box transcription factor 5.	0.766
GJA1	GATA4	ENSAMEP00000020751	ENSAMEP00000006528	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	GATA binding protein 4.	0.515
GJA1	GJA5	ENSAMEP00000020751	ENSAMEP00000021349	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.676
GJA1	INS-IGF2	ENSAMEP00000020751	ENSAMEP00000002279	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	INS-IGF2 readthrough; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.439
GJA1	NKX2-5	ENSAMEP00000020751	ENSAMEP00000011903	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	NK2 homeobox 5.	0.485
GJA1	NPPA	ENSAMEP00000020751	ENSAMEP00000010367	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Natriuretic peptide A.	0.485
GJA1	RYR2	ENSAMEP00000020751	ENSAMEP00000003073	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Ryanodine receptor 2.	0.499
GJA1	TBX5	ENSAMEP00000020751	ENSAMEP00000001182	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	T-box transcription factor 5.	0.449
GJA5	GJA1	ENSAMEP00000021349	ENSAMEP00000020751	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.676
GJA5	NKX2-5	ENSAMEP00000021349	ENSAMEP00000011903	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	NK2 homeobox 5.	0.507
GJA5	NPPA	ENSAMEP00000021349	ENSAMEP00000010367	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Natriuretic peptide A.	0.521
GJA5	RYR2	ENSAMEP00000021349	ENSAMEP00000003073	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Ryanodine receptor 2.	0.436
GJA5	TBX5	ENSAMEP00000021349	ENSAMEP00000001182	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	T-box transcription factor 5.	0.516
HCN1	HCN2	ENSAMEP00000006154	ENSAMEP00000002875	Hyperpolarization activated cyclic nucleotide gated potassium channel 1.	Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2.	0.901