(28 nodes) MHC protein complex, and MHC class I peptide loading complex network (Ailuropoda melanoleuca)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TAPBP	TAP binding protein. (462 aa)
	AIME-152	Ig-like domain-containing protein; Belongs to the MHC class I family. (366 aa)
	HLA-DPB1	Major histocompatibility complex, class II, DP beta 1. (236 aa)
	HLA-DPA1	Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (259 aa)
	HLA-DOA	Major histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (252 aa)
	HLA-DMA	Major histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (261 aa)
	G1L599_AILME	Ig-like domain-containing protein. (268 aa)
	TAP1	Transporter 1, ATP binding cassette subfamily B member. (811 aa)
	G1L5K5_AILME	Uncharacterized protein. (305 aa)
	TAP2	Uncharacterized protein. (768 aa)
	G1L5S3_AILME	Ig-like domain-containing protein. (276 aa)
	AIME-1906	Ig-like domain-containing protein; Belongs to the MHC class I family. (366 aa)
	HLA-DQB2	Major histocompatibility complex, class II, DQ beta 2. (256 aa)
	G1L6E1_AILME	Ig-like domain-containing protein; Belongs to the MHC class II family. (251 aa)
	LOC100463773	Ig-like domain-containing protein; Belongs to the MHC class II family. (255 aa)
	G1L6H3_AILME	Ig-like domain-containing protein. (285 aa)
	HLA-DRA	Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa)
	KLRD1	Killer cell lectin like receptor D1. (181 aa)
	CD74	CD74 molecule. (295 aa)
	G1LKQ4_AILME	DUF1968 domain-containing protein. (125 aa)
	LOC105234428	Ig-like domain-containing protein; Belongs to the MHC class I family. (149 aa)
	G1LUZ7_AILME	Ig-like domain-containing protein. (124 aa)
	CALR	Calreticulin. (417 aa)
	ABCB9	ATP binding cassette subfamily B member 9. (797 aa)
	PDIA3	Protein disulfide-isomerase. (505 aa)
	NLRC5	NLR family CARD domain containing 5. (1900 aa)
	B2M	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (92 aa)
	G1MMC4_AILME	Ig-like domain-containing protein. (91 aa)

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCB9	NLRC5	ENSAMEP00000015843	ENSAMEP00000017796	ATP binding cassette subfamily B member 9.	NLR family CARD domain containing 5.	0.510
ABCB9	PDIA3	ENSAMEP00000015843	ENSAMEP00000016090	ATP binding cassette subfamily B member 9.	Protein disulfide-isomerase.	0.455
ABCB9	TAPBP	ENSAMEP00000015843	ENSAMEP00000001603	ATP binding cassette subfamily B member 9.	TAP binding protein.	0.719
AIME-152	AIME-1906	ENSAMEP00000001813	ENSAMEP00000002421	Ig-like domain-containing protein; Belongs to the MHC class I family.	Ig-like domain-containing protein; Belongs to the MHC class I family.	0.901
AIME-152	B2M	ENSAMEP00000001813	ENSAMEP00000020170	Ig-like domain-containing protein; Belongs to the MHC class I family.	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	0.997
AIME-152	CALR	ENSAMEP00000001813	ENSAMEP00000013174	Ig-like domain-containing protein; Belongs to the MHC class I family.	Calreticulin.	0.944
AIME-152	G1LKQ4_AILME	ENSAMEP00000001813	ENSAMEP00000007520	Ig-like domain-containing protein; Belongs to the MHC class I family.	DUF1968 domain-containing protein.	0.953
AIME-152	G1MMC4_AILME	ENSAMEP00000001813	ENSAMEP00000020515	Ig-like domain-containing protein; Belongs to the MHC class I family.	Ig-like domain-containing protein.	0.900
AIME-152	KLRD1	ENSAMEP00000001813	ENSAMEP00000004875	Ig-like domain-containing protein; Belongs to the MHC class I family.	Killer cell lectin like receptor D1.	0.942
AIME-152	PDIA3	ENSAMEP00000001813	ENSAMEP00000016090	Ig-like domain-containing protein; Belongs to the MHC class I family.	Protein disulfide-isomerase.	0.943
AIME-152	TAP1	ENSAMEP00000001813	ENSAMEP00000002122	Ig-like domain-containing protein; Belongs to the MHC class I family.	Transporter 1, ATP binding cassette subfamily B member.	0.421
AIME-152	TAPBP	ENSAMEP00000001813	ENSAMEP00000001603	Ig-like domain-containing protein; Belongs to the MHC class I family.	TAP binding protein.	0.958
AIME-1906	AIME-152	ENSAMEP00000002421	ENSAMEP00000001813	Ig-like domain-containing protein; Belongs to the MHC class I family.	Ig-like domain-containing protein; Belongs to the MHC class I family.	0.901
AIME-1906	B2M	ENSAMEP00000002421	ENSAMEP00000020170	Ig-like domain-containing protein; Belongs to the MHC class I family.	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	0.959
AIME-1906	CALR	ENSAMEP00000002421	ENSAMEP00000013174	Ig-like domain-containing protein; Belongs to the MHC class I family.	Calreticulin.	0.944
AIME-1906	G1LKQ4_AILME	ENSAMEP00000002421	ENSAMEP00000007520	Ig-like domain-containing protein; Belongs to the MHC class I family.	DUF1968 domain-containing protein.	0.953
AIME-1906	G1MMC4_AILME	ENSAMEP00000002421	ENSAMEP00000020515	Ig-like domain-containing protein; Belongs to the MHC class I family.	Ig-like domain-containing protein.	0.900
AIME-1906	KLRD1	ENSAMEP00000002421	ENSAMEP00000004875	Ig-like domain-containing protein; Belongs to the MHC class I family.	Killer cell lectin like receptor D1.	0.942
AIME-1906	PDIA3	ENSAMEP00000002421	ENSAMEP00000016090	Ig-like domain-containing protein; Belongs to the MHC class I family.	Protein disulfide-isomerase.	0.943
AIME-1906	TAP1	ENSAMEP00000002421	ENSAMEP00000002122	Ig-like domain-containing protein; Belongs to the MHC class I family.	Transporter 1, ATP binding cassette subfamily B member.	0.421