(57 nodes) Mixed, incl. Cadherin binding, and Desmosomal cadherin network (Ailuropoda melanoleuca)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100468630	Plakophilin 4. (638 aa)
	CD151	Tetraspanin. (313 aa)
	G1L3R6_AILME	Uncharacterized protein. (478 aa)
	OSCP1	Organic solute carrier partner 1. (375 aa)
	CDH11	Cadherin 11; Cadherins are calcium-dependent cell adhesion proteins. (798 aa)
	PPL	Periplakin. (1754 aa)
	MOB2	MOB kinase activator 2. (266 aa)
	IQCM	Uncharacterized protein. (179 aa)
	G1LAL1_AILME	Uncharacterized protein. (296 aa)
	FAT3	FAT atypical cadherin 3. (4589 aa)
	UNC5CL	Unc-5 family C-terminal like. (518 aa)
	JUP	Junction plakoglobin. (779 aa)
	CDH6	Cadherin 6; Cadherins are calcium-dependent cell adhesion proteins. (790 aa)
	PLEC	Plectin. (4622 aa)
	CDH13	Cadherin 13. (455 aa)
	FJX1	Four-jointed box kinase 1. (263 aa)
	CDH1	Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (883 aa)
	DSC3	Desmocollin 3; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (881 aa)
	DSC2	Desmocollin 2; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (697 aa)
	DSC1	Desmocollin 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (897 aa)
	DSG1	Desmoglein 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1065 aa)
	DSG3	Desmoglein 3; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (971 aa)
	DSG2	Desmoglein 2. (1118 aa)
	PKP2	Plakophilin 2. (882 aa)
	EVPL	Envoplakin. (2033 aa)
	PERP	P53 apoptosis effector related to PMP22. (193 aa)
	MID1	Midline 1. (666 aa)
	G1LUU5_AILME	Uncharacterized protein. (621 aa)
	G1LUX6_AILME	Calponin-homology (CH) domain-containing protein. (115 aa)
	PKP3	Plakophilin 3. (803 aa)
	MACF1	Uncharacterized protein. (7251 aa)
	SLC6A18	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (610 aa)
	G1LWA2_AILME	Uncharacterized protein. (477 aa)
	PANDA_007547	Uncharacterized protein. (78 aa)
	PANDA_019313	Uncharacterized protein. (188 aa)
	PANDA_019314	Uncharacterized protein. (99 aa)
	ARVCF	ARVCF delta catenin family member. (957 aa)
	CDH2	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (889 aa)
	KAZN	Kazrin, periplakin interacting protein. (699 aa)
	PKP1	Plakophilin 1. (727 aa)
	CDH4	Cadherin 4; Cadherins are calcium-dependent cell adhesion proteins. (862 aa)
	CDH22	Cadherin 22; Cadherins are calcium-dependent cell adhesion proteins. (637 aa)
	CTNND2	Uncharacterized protein. (646 aa)
	ARFGEF2	ADP ribosylation factor guanine nucleotide exchange factor 2. (1795 aa)
	G1M6F2_AILME	CA domain-containing protein. (100 aa)
	CTNND1	Catenin delta 1. (971 aa)
	GLRX2	Glutaredoxin 2. (129 aa)
	DCHS1	Dachsous cadherin-related 1. (3271 aa)
	CDH7	Cadherin 7; Cadherins are calcium-dependent cell adhesion proteins. (785 aa)
	CTNNA1	Catenin alpha 1. (812 aa)
	LOC105234678	Uncharacterized protein. (181 aa)
	CDH16	Cadherin 16. (829 aa)
	DSP	Desmoplakin. (2827 aa)
	COL17A1	Collagen type XVII alpha 1 chain. (1464 aa)
	CTNNA3	Uncharacterized protein. (193 aa)
	DCHS2	Dachsous cadherin-related 2. (3261 aa)
	OR6K6	Olfactory receptor. (341 aa)

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARFGEF2	DCHS1	ENSAMEP00000014566	ENSAMEP00000017158	ADP ribosylation factor guanine nucleotide exchange factor 2.	Dachsous cadherin-related 1.	0.577
ARFGEF2	DCHS2	ENSAMEP00000014566	ENSAMEP00000019508	ADP ribosylation factor guanine nucleotide exchange factor 2.	Dachsous cadherin-related 2.	0.577
ARFGEF2	MOB2	ENSAMEP00000014566	ENSAMEP00000002089	ADP ribosylation factor guanine nucleotide exchange factor 2.	MOB kinase activator 2.	0.444
ARVCF	CDH1	ENSAMEP00000012293	ENSAMEP00000008223	ARVCF delta catenin family member.	Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins.	0.585
ARVCF	CDH11	ENSAMEP00000012293	ENSAMEP00000001555	ARVCF delta catenin family member.	Cadherin 11; Cadherins are calcium-dependent cell adhesion proteins.	0.620
ARVCF	CDH13	ENSAMEP00000012293	ENSAMEP00000006833	ARVCF delta catenin family member.	Cadherin 13.	0.512
ARVCF	CDH16	ENSAMEP00000012293	ENSAMEP00000018119	ARVCF delta catenin family member.	Cadherin 16.	0.539
ARVCF	CDH2	ENSAMEP00000012293	ENSAMEP00000012604	ARVCF delta catenin family member.	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	0.623
ARVCF	CDH4	ENSAMEP00000012293	ENSAMEP00000013559	ARVCF delta catenin family member.	Cadherin 4; Cadherins are calcium-dependent cell adhesion proteins.	0.623
ARVCF	CDH6	ENSAMEP00000012293	ENSAMEP00000006317	ARVCF delta catenin family member.	Cadherin 6; Cadherins are calcium-dependent cell adhesion proteins.	0.421
ARVCF	CDH7	ENSAMEP00000012293	ENSAMEP00000017274	ARVCF delta catenin family member.	Cadherin 7; Cadherins are calcium-dependent cell adhesion proteins.	0.590
ARVCF	CTNNA1	ENSAMEP00000012293	ENSAMEP00000017563	ARVCF delta catenin family member.	Catenin alpha 1.	0.605
ARVCF	CTNNA3	ENSAMEP00000012293	ENSAMEP00000019157	ARVCF delta catenin family member.	Uncharacterized protein.	0.605
ARVCF	DCHS1	ENSAMEP00000012293	ENSAMEP00000017158	ARVCF delta catenin family member.	Dachsous cadherin-related 1.	0.419
ARVCF	DCHS2	ENSAMEP00000012293	ENSAMEP00000019508	ARVCF delta catenin family member.	Dachsous cadherin-related 2.	0.419
ARVCF	DSG2	ENSAMEP00000012293	ENSAMEP00000008597	ARVCF delta catenin family member.	Desmoglein 2.	0.406
ARVCF	DSG3	ENSAMEP00000012293	ENSAMEP00000008580	ARVCF delta catenin family member.	Desmoglein 3; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	0.406
ARVCF	EVPL	ENSAMEP00000012293	ENSAMEP00000010576	ARVCF delta catenin family member.	Envoplakin.	0.581
ARVCF	G1L3R6_AILME	ENSAMEP00000012293	ENSAMEP00000001526	ARVCF delta catenin family member.	Uncharacterized protein.	0.585
ARVCF	G1LWA2_AILME	ENSAMEP00000012293	ENSAMEP00000011353	ARVCF delta catenin family member.	Uncharacterized protein.	0.605