(16 nodes) Mixed, incl. Dopaminergic neuron differentiation, and T-cell leukemia homeobox protein 1/2/3 network (Ailuropoda melanoleuca)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GBX2	Gastrulation brain homeobox 2. (286 aa)
	OTX2	Orthodenticle homeobox 2. (297 aa)
	ZIC3	Zic family member 3. (465 aa)
	TLX3	T cell leukemia homeobox 3. (300 aa)
	DBX1	Developing brain homeobox 1. (375 aa)
	SLC6A5	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (797 aa)
	EVX1	Even-skipped homeobox 1. (255 aa)
	LMX1A	LIM homeobox transcription factor 1 alpha. (382 aa)
	EN1	Homeobox protein engrailed-like. (207 aa)
	LHX5	LIM homeobox 5. (407 aa)
	NR4A2	Nuclear receptor subfamily 4 group A member 2. (598 aa)
	SLC6A3	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (627 aa)
	FOXA2	Forkhead box A2. (465 aa)
	LMX1B	LIM homeobox transcription factor 1 beta. (402 aa)
	TLX1	T cell leukemia homeobox 1. (218 aa)
	OLIG3	Oligodendrocyte transcription factor 3. (272 aa)

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DBX1	EVX1	ENSAMEP00000004914	ENSAMEP00000006187	Developing brain homeobox 1.	Even-skipped homeobox 1.	0.551
DBX1	LHX5	ENSAMEP00000004914	ENSAMEP00000009054	Developing brain homeobox 1.	LIM homeobox 5.	0.503
DBX1	LMX1A	ENSAMEP00000004914	ENSAMEP00000006955	Developing brain homeobox 1.	LIM homeobox transcription factor 1 alpha.	0.492
DBX1	LMX1B	ENSAMEP00000004914	ENSAMEP00000017585	Developing brain homeobox 1.	LIM homeobox transcription factor 1 beta.	0.492
DBX1	OLIG3	ENSAMEP00000004914	ENSAMEP00000020698	Developing brain homeobox 1.	Oligodendrocyte transcription factor 3.	0.556
DBX1	SLC6A5	ENSAMEP00000004914	ENSAMEP00000005046	Developing brain homeobox 1.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.611
EN1	EVX1	ENSAMEP00000008895	ENSAMEP00000006187	Homeobox protein engrailed-like.	Even-skipped homeobox 1.	0.438
EN1	FOXA2	ENSAMEP00000008895	ENSAMEP00000016667	Homeobox protein engrailed-like.	Forkhead box A2.	0.758
EN1	NR4A2	ENSAMEP00000008895	ENSAMEP00000010319	Homeobox protein engrailed-like.	Nuclear receptor subfamily 4 group A member 2.	0.599
EVX1	DBX1	ENSAMEP00000006187	ENSAMEP00000004914	Even-skipped homeobox 1.	Developing brain homeobox 1.	0.551
EVX1	EN1	ENSAMEP00000006187	ENSAMEP00000008895	Even-skipped homeobox 1.	Homeobox protein engrailed-like.	0.438
EVX1	SLC6A5	ENSAMEP00000006187	ENSAMEP00000005046	Even-skipped homeobox 1.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.476
FOXA2	EN1	ENSAMEP00000016667	ENSAMEP00000008895	Forkhead box A2.	Homeobox protein engrailed-like.	0.758
FOXA2	GBX2	ENSAMEP00000016667	ENSAMEP00000001871	Forkhead box A2.	Gastrulation brain homeobox 2.	0.401
FOXA2	LMX1A	ENSAMEP00000016667	ENSAMEP00000006955	Forkhead box A2.	LIM homeobox transcription factor 1 alpha.	0.696
FOXA2	LMX1B	ENSAMEP00000016667	ENSAMEP00000017585	Forkhead box A2.	LIM homeobox transcription factor 1 beta.	0.696
FOXA2	NR4A2	ENSAMEP00000016667	ENSAMEP00000010319	Forkhead box A2.	Nuclear receptor subfamily 4 group A member 2.	0.553
FOXA2	OTX2	ENSAMEP00000016667	ENSAMEP00000002440	Forkhead box A2.	Orthodenticle homeobox 2.	0.795
FOXA2	SLC6A3	ENSAMEP00000016667	ENSAMEP00000011433	Forkhead box A2.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.625
GBX2	FOXA2	ENSAMEP00000001871	ENSAMEP00000016667	Gastrulation brain homeobox 2.	Forkhead box A2.	0.401