(23 nodes) Rac protein signal transduction network (Ailuropoda melanoleuca)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EPS8	Epidermal growth factor receptor pathway substrate 8. (842 aa)
	G1L1A9_AILME	Uncharacterized protein. (190 aa)
	NCKAP1	NCK associated protein 1. (1102 aa)
	NF1	Neurofibromin 1. (2820 aa)
	CDH13	Cadherin 13. (455 aa)
	RAC1	Rac family small GTPase 1. (198 aa)
	KRAS	KRAS proto-oncogene, GTPase. (189 aa)
	NISCH	Nischarin. (1593 aa)
	AIF1	Allograft inflammatory factor 1. (159 aa)
	RAC2	Rac family small GTPase 2. (192 aa)
	WASF2	WASP family member 2. (496 aa)
	CYFIP1	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1256 aa)
	G1M6F2_AILME	CA domain-containing protein. (100 aa)
	BRK1	Uncharacterized protein. (90 aa)
	WASF1	WASP family member 1. (559 aa)
	FARP2	FERM, ARH/RhoGEF and pleckstrin domain protein 2. (1034 aa)
	KIAA0355	KIAA0355. (1069 aa)
	RAC3	Rac family small GTPase 3. (189 aa)
	DBNL	Drebrin like. (408 aa)
	ELMO1	Engulfment and cell motility 1. (727 aa)
	RHOH	Ras homolog family member H. (191 aa)
	RHOG	Ras homolog family member G. (191 aa)
	PANDA_019199	Uncharacterized protein. (191 aa)

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRK1	CYFIP1	ENSAMEP00000016935	ENSAMEP00000014558	Uncharacterized protein.	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.	0.998
BRK1	ELMO1	ENSAMEP00000016935	ENSAMEP00000019173	Uncharacterized protein.	Engulfment and cell motility 1.	0.478
BRK1	G1L1A9_AILME	ENSAMEP00000016935	ENSAMEP00000000661	Uncharacterized protein.	Uncharacterized protein.	0.607
BRK1	NCKAP1	ENSAMEP00000016935	ENSAMEP00000001229	Uncharacterized protein.	NCK associated protein 1.	0.999
BRK1	PANDA_019199	ENSAMEP00000016935	ENSAMEP00000020649	Uncharacterized protein.	Uncharacterized protein.	0.492
BRK1	RAC1	ENSAMEP00000016935	ENSAMEP00000007121	Uncharacterized protein.	Rac family small GTPase 1.	0.607
BRK1	RAC2	ENSAMEP00000016935	ENSAMEP00000010402	Uncharacterized protein.	Rac family small GTPase 2.	0.656
BRK1	RAC3	ENSAMEP00000016935	ENSAMEP00000018344	Uncharacterized protein.	Rac family small GTPase 3.	0.607
BRK1	RHOG	ENSAMEP00000016935	ENSAMEP00000020570	Uncharacterized protein.	Ras homolog family member G.	0.492
BRK1	RHOH	ENSAMEP00000016935	ENSAMEP00000019532	Uncharacterized protein.	Ras homolog family member H.	0.428
BRK1	WASF1	ENSAMEP00000016935	ENSAMEP00000017261	Uncharacterized protein.	WASP family member 1.	0.996
BRK1	WASF2	ENSAMEP00000016935	ENSAMEP00000011549	Uncharacterized protein.	WASP family member 2.	0.989
CDH13	G1M6F2_AILME	ENSAMEP00000006833	ENSAMEP00000014922	Cadherin 13.	CA domain-containing protein.	0.896
CYFIP1	BRK1	ENSAMEP00000014558	ENSAMEP00000016935	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.	Uncharacterized protein.	0.998
CYFIP1	ELMO1	ENSAMEP00000014558	ENSAMEP00000019173	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.	Engulfment and cell motility 1.	0.416
CYFIP1	G1L1A9_AILME	ENSAMEP00000014558	ENSAMEP00000000661	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.	Uncharacterized protein.	0.643
CYFIP1	NCKAP1	ENSAMEP00000014558	ENSAMEP00000001229	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.	NCK associated protein 1.	0.998
CYFIP1	PANDA_019199	ENSAMEP00000014558	ENSAMEP00000020649	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.	Uncharacterized protein.	0.593
CYFIP1	RAC1	ENSAMEP00000014558	ENSAMEP00000007121	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.	Rac family small GTPase 1.	0.643
CYFIP1	RAC2	ENSAMEP00000014558	ENSAMEP00000010402	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.	Rac family small GTPase 2.	0.965