STRINGSTRING
G1MNJ1_AILME G1MNJ1_AILME SYT11 SYT11 RAPGEF4 RAPGEF4 ATP13A2 ATP13A2 GRIN3A GRIN3A SYT6 SYT6 SYT13 SYT13 RAB5A RAB5A NCKAP1L NCKAP1L LOC100467242 LOC100467242 CFTR CFTR G1L3H5_AILME G1L3H5_AILME NLGN1 NLGN1 TPCN2 TPCN2 LYN LYN F2RL1 F2RL1 SYT8 SYT8 SYTL4 SYTL4 VAMP8 VAMP8 RAB10 RAB10 AP1G1 AP1G1 G1L7E0_AILME G1L7E0_AILME SDC1 SDC1 LGI3 LGI3 RAB15 RAB15 SYT5 SYT5 RAB3C RAB3C NOTCH1 NOTCH1 FBXL20 FBXL20 SNX4 SNX4 GIT1 GIT1 CD177 CD177 STXBP3 STXBP3 CADPS2 CADPS2 LAMP1 LAMP1 KIAA0100 KIAA0100 PRAM1 PRAM1 SNF8 SNF8 RAP1A RAP1A G1LGB6_AILME G1LGB6_AILME G1LGE8_AILME G1LGE8_AILME GIPC3 GIPC3 GIPC3-2 GIPC3-2 PREPL PREPL BLK BLK VPS4B VPS4B VAMP7 VAMP7 SYT4 SYT4 GSK3B GSK3B APBA1 APBA1 PLA2G3 PLA2G3 SYT9 SYT9 RAB12 RAB12 GIPC2 GIPC2 STX1B STX1B CHMP2A CHMP2A VPS4A VPS4A CACNA1H CACNA1H BAIAP3 BAIAP3 SEPTIN1 SEPTIN1 DOC2B DOC2B RPH3AL RPH3AL RALA RALA BACE1 BACE1 REST REST SCAMP5 SCAMP5 RAP1B RAP1B RPH3A RPH3A CACNB4 CACNB4 SYT10 SYT10 BCR BCR G1MNY1_AILME G1MNY1_AILME RAB3B RAB3B IL1RAPL1 IL1RAPL1 EXPH5 EXPH5 RAB8A RAB8A UNC13D UNC13D RAC2 RAC2 G1LU13_AILME G1LU13_AILME G1LVA0_AILME G1LVA0_AILME PFN2 PFN2 RAB3D RAB3D STAM STAM SYT12 SYT12 RAB33B RAB33B CACNA1I CACNA1I FGR FGR SYT17 SYT17 RAB3A RAB3A STX1A STX1A SEPTIN5 SEPTIN5 SEPTIN4-2 SEPTIN4-2 HYAL3 HYAL3 RAB13 RAB13 SYT2 SYT2 SNAPIN SNAPIN SYP SYP CHRNA5 CHRNA5 CACNA1A CACNA1A SYT3 SYT3 CACNB2 CACNB2 CSPG5 CSPG5 ATP9A ATP9A SYT1 SYT1 GIPC1 GIPC1 CDK5 CDK5 FES FES DVL1 DVL1 P2RX7 P2RX7 PRKCB PRKCB ADCY1 ADCY1 SPHK2 SPHK2 DOC2A DOC2A SYNPR SYNPR BRAF BRAF DNM1 DNM1 CADPS CADPS ZP3 ZP3 ANXA1 ANXA1 ADRA2A ADRA2A C12orf4 C12orf4 LRRK2 LRRK2 PRKN PRKN PANDA_009467 PANDA_009467 G1MBM7_AILME G1MBM7_AILME CACNA1B CACNA1B STXBP5 STXBP5 MICAL1 MICAL1 SEPTIN2 SEPTIN2 SYT7 SYT7 PCLO PCLO STXBP1 STXBP1 VPS18 VPS18 RAB27B RAB27B SYK SYK CD160 CD160 G1MGQ4_AILME G1MGQ4_AILME HGS HGS IL13 IL13 RAB26 RAB26 TSG101 TSG101 PDPK1 PDPK1 DGKI DGKI KCTD7 KCTD7 RAB24 RAB24 FOXF1 FOXF1 RAB27A RAB27A PANDA_022285 PANDA_022285 RAB9A RAB9A CNR1 CNR1 CHRM2 CHRM2 PANDA_020942 PANDA_020942
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
G1MNJ1_AILMEIg-like domain-containing protein. (93 aa)
SYT11Synaptotagmin 11. (436 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4. (1011 aa)
ATP13A2ATPase cation transporting 13A2. (1098 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A. (1118 aa)
SYT6Synaptotagmin 6. (514 aa)
SYT13Synaptotagmin 13. (426 aa)
RAB5ARAB5A, member RAS oncogene family. (215 aa)
NCKAP1LNCK associated protein 1 like. (1137 aa)
LOC100467242Uncharacterized protein. (387 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1500 aa)
G1L3H5_AILMEIg-like domain-containing protein. (314 aa)
NLGN1COesterase domain-containing protein. (616 aa)
TPCN2Uncharacterized protein. (759 aa)
LYNTyrosine-protein kinase. (512 aa)
F2RL1F2R like trypsin receptor 1. (401 aa)
SYT8Synaptotagmin 8. (345 aa)
SYTL4Synaptotagmin like 4. (671 aa)
VAMP8Vesicle associated membrane protein 8. (110 aa)
RAB10RAB10, member RAS oncogene family. (200 aa)
AP1G1AP-1 complex subunit gamma. (844 aa)
G1L7E0_AILMEUncharacterized protein. (383 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (302 aa)
LGI3Leucine rich repeat LGI family member 3. (548 aa)
RAB15RAB15, member RAS oncogene family. (214 aa)
SYT5Synaptotagmin 5. (386 aa)
RAB3CRAB3C, member RAS oncogene family. (220 aa)
NOTCH1Notch receptor 1. (2435 aa)
FBXL20F-box and leucine rich repeat protein 20. (436 aa)
SNX4Sorting nexin 4. (436 aa)
GIT1GIT ArfGAP 1. (773 aa)
CD177CD177 molecule. (434 aa)
STXBP3Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (593 aa)
CADPS2Calcium dependent secretion activator 2. (1156 aa)
LAMP1Lysosomal associated membrane protein 1. (424 aa)
KIAA0100KIAA0100. (2232 aa)
PRAM1PML-RARA regulated adaptor molecule 1. (597 aa)
SNF8Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
G1LGB6_AILMEUncharacterized protein. (114 aa)
G1LGE8_AILMEUncharacterized protein. (1320 aa)
GIPC3GIPC PDZ domain containing family member 3. (332 aa)
GIPC3-2Uncharacterized protein. (588 aa)
PREPLProlyl endopeptidase like. (727 aa)
BLKTyrosine-protein kinase. (500 aa)
VPS4BVacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (444 aa)
VAMP7Vesicle associated membrane protein 7; Belongs to the synaptobrevin family. (220 aa)
SYT4Synaptotagmin 4. (427 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
APBA1Amyloid beta precursor protein binding family A member 1. (838 aa)
PLA2G3Phospholipase A2 group III. (513 aa)
SYT9Synaptotagmin 9. (348 aa)
RAB12RAB12, member RAS oncogene family. (231 aa)
GIPC2GIPC PDZ domain containing family member 2. (316 aa)
STX1BSyntaxin 1B; Belongs to the syntaxin family. (288 aa)
CHMP2ACharged multivesicular body protein 2A. (222 aa)
VPS4AUncharacterized protein; Belongs to the AAA ATPase family. (442 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2153 aa)
BAIAP3BAI1 associated protein 3. (1182 aa)
SEPTIN1Septin 1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (368 aa)
DOC2BDouble C2 domain beta. (304 aa)
RPH3ALRabphilin 3A like (without C2 domains). (315 aa)
RALARAS like proto-oncogene A. (206 aa)
BACE1Beta-secretase 1; Belongs to the peptidase A1 family. (501 aa)
RESTRE1 silencing transcription factor. (1038 aa)
SCAMP5Secretory carrier-associated membrane protein. (242 aa)
RAP1BUncharacterized protein. (184 aa)
RPH3ARabphilin 3A. (702 aa)
CACNB4SH3 domain-containing protein. (500 aa)
SYT10Synaptotagmin 10. (523 aa)
BCRBCR activator of RhoGEF and GTPase. (1149 aa)
G1MNY1_AILMECOesterase domain-containing protein. (137 aa)
RAB3BRAB3B, member RAS oncogene family. (230 aa)
IL1RAPL1Uncharacterized protein. (440 aa)
EXPH5Exophilin 5. (1944 aa)
RAB8ARAB8A, member RAS oncogene family. (207 aa)
UNC13DUnc-13 homolog D. (1087 aa)
RAC2Rac family small GTPase 2. (192 aa)
G1LU13_AILMEUncharacterized protein. (417 aa)
G1LVA0_AILMEUncharacterized protein. (176 aa)
PFN2Profilin; Belongs to the profilin family. (98 aa)
RAB3DRAB3D, member RAS oncogene family. (219 aa)
STAMSignal transducing adaptor molecule. (534 aa)
SYT12Synaptotagmin 12. (424 aa)
RAB33BRAB33B, member RAS oncogene family. (243 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (1782 aa)
FGRTyrosine-protein kinase. (526 aa)
SYT17Synaptotagmin 17. (470 aa)
RAB3ARAB3A, member RAS oncogene family. (228 aa)
STX1ASyntaxin 1A; Belongs to the syntaxin family. (288 aa)
SEPTIN5Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (417 aa)
SEPTIN4-2Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (581 aa)
HYAL3Hyaluronidase. (419 aa)
RAB13Uncharacterized protein. (238 aa)
SYT2Synaptotagmin 2. (437 aa)
SNAPINSNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (135 aa)
SYPSynaptophysin. (313 aa)
CHRNA5Cholinergic receptor nicotinic alpha 5 subunit. (453 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (1997 aa)
SYT3Synaptotagmin 3. (591 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (549 aa)
CSPG5Chondroitin sulfate proteoglycan 5. (541 aa)
ATP9APhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1044 aa)
SYT1Synaptotagmin 1. (423 aa)
GIPC1GIPC PDZ domain containing family member 1. (332 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (819 aa)
DVL1Dishevelled segment polarity protein 1. (700 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (661 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1049 aa)
SPHK2Sphingosine kinase 2. (663 aa)
DOC2ADouble C2-like domain-containing protein. (400 aa)
SYNPRSynaptoporin. (285 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (787 aa)
DNM1Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (864 aa)
CADPSUncharacterized protein. (1058 aa)
ZP3ZP domain-containing protein. (426 aa)
ANXA1Annexin. (345 aa)
ADRA2AAdrenoceptor alpha 2A. (343 aa)
C12orf4Chromosome 12 open reading frame 4. (554 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
PRKNUbiquitin-like domain-containing protein. (287 aa)
PANDA_009467zf-RING_14 domain-containing protein. (74 aa)
G1MBM7_AILMERBR-type E3 ubiquitin transferase. (105 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (1632 aa)
STXBP5Syntaxin binding protein 5. (1152 aa)
MICAL1Microtubule associated monooxygenase, calponin and LIM domain containing 1. (1074 aa)
SEPTIN2Septin 2; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (358 aa)
SYT7Synaptotagmin 7. (690 aa)
PCLOPiccolo presynaptic cytomatrix protein. (5116 aa)
STXBP1Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family. (603 aa)
VPS18VPS18 core subunit of CORVET and HOPS complexes. (973 aa)
RAB27BRAB27B, member RAS oncogene family. (218 aa)
SYKTyrosine-protein kinase. (630 aa)
CD160CD160 molecule. (231 aa)
G1MGQ4_AILMEUncharacterized protein. (42 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (784 aa)
IL13Interleukin 13. (145 aa)
RAB26RAB26, member RAS oncogene family. (259 aa)
TSG101Tumor susceptibility 101. (391 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (558 aa)
DGKIDiacylglycerol kinase. (925 aa)
KCTD7Uncharacterized protein. (704 aa)
RAB24RAB24, member RAS oncogene family. (203 aa)
FOXF1Forkhead box F1. (387 aa)
RAB27ARAB27A, member RAS oncogene family. (221 aa)
PANDA_022285Uncharacterized protein. (184 aa)
RAB9ARAB9A, member RAS oncogene family. (201 aa)
CNR1Cannabinoid receptor 1; Belongs to the G-protein coupled receptor 1 family. (472 aa)
CHRM2Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (466 aa)
PANDA_020942RabBD domain-containing protein. (56 aa)
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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