STRINGSTRING
RUFY3 RUFY3 CDK5 CDK5 CYFIP1 CYFIP1 ARPC3 ARPC3 SHTN1 SHTN1 SPATA13 SPATA13 STX3 STX3 ACTN1 ACTN1 CDC42 CDC42 ITGB3 ITGB3 ACTR3 ACTR3 CORO1A CORO1A LIMK1 LIMK1 MYO10 MYO10 SNX2 SNX2 BRK1 BRK1 PKN2 PKN2 ILK ILK WASF1 WASF1 APBB1 APBB1 CORO1C CORO1C CARMIL3 CARMIL3 ABITRAM ABITRAM ARHGEF7 ARHGEF7 CFL1 CFL1 RAC3 RAC3 ITGB1 ITGB1 ACTG2 ACTG2 FAM89B FAM89B CARMIL2 CARMIL2 P4HB P4HB DBNL DBNL STMN2 STMN2 PDLIM4 PDLIM4 MYO1G MYO1G VILL VILL CDC42BPB CDC42BPB RHOB RHOB KCNA2 KCNA2 KCNA1 KCNA1 ARHGAP31 ARHGAP31 ROCK1 ROCK1 RAC1 RAC1 DGKZ DGKZ G1LJH1_AILME G1LJH1_AILME FSCN1 FSCN1 VAMP7 VAMP7 UNC5C UNC5C G1LH72_AILME G1LH72_AILME G1LGV4_AILME G1LGV4_AILME PLEKHH2 PLEKHH2 INPPL1 INPPL1 PAK1 PAK1 DPP4 DPP4 ABLIM3 ABLIM3 BCAR1 BCAR1 ACTC1 ACTC1 ABI3 ABI3 IGF2BP1 IGF2BP1 MYLK MYLK FSCN3 FSCN3 FLOT2 FLOT2 WASL WASL PLXND1 PLXND1 AMOT AMOT STX2 STX2 TSC1 TSC1 CORO6 CORO6 G1LBQ0_AILME G1LBQ0_AILME SYNE2 SYNE2 G1LBN4_AILME G1LBN4_AILME CCDC88A CCDC88A RHOC RHOC G1L9K7_AILME G1L9K7_AILME PKD2 PKD2 DPYSL3 DPYSL3 VIL1 VIL1 ARHGEF6 ARHGEF6 G1L7E7_AILME G1L7E7_AILME FGD1 FGD1 SNX1 SNX1 ARPC5 ARPC5 MYH10 MYH10 KITLG KITLG CAPG CAPG ABI1 ABI1 WASF3 WASF3 IQGAP2 IQGAP2 VASP VASP GSN GSN ACTA2 ACTA2 CORO1B CORO1B SLC39A6 SLC39A6 PIP5K1A PIP5K1A TTN TTN G1L1A9_AILME G1L1A9_AILME PABPC1 PABPC1 PTK2B PTK2B AJUBA AJUBA CTTN CTTN G1LLP6_AILME G1LLP6_AILME CD44 CD44 NME1-NME2 NME1-NME2 NF2 NF2 KPTN KPTN CAPRIN1 CAPRIN1 ITGAV ITGAV ITGB1BP1 ITGB1BP1 CLRN1 CLRN1 ACTA1 ACTA1 GDPD2 GDPD2 AIF1 AIF1 PLCG1 PLCG1 CIB3 CIB3 RAC2 RAC2 CARMIL1 CARMIL1 SH3BP1 SH3BP1 PDXP PDXP SPEF1 SPEF1 PIK3CA PIK3CA WASF2 WASF2 SCYL3 SCYL3 EVL EVL PHACTR4 PHACTR4 EPHA2 EPHA2 HAX1 HAX1 RAB13 RAB13 PPP1R9B PPP1R9B NGFR NGFR DAG1 DAG1 RHOA RHOA APC APC G1M284_AILME G1M284_AILME ABI2 ABI2 FLOT1 FLOT1 ACTR3B ACTR3B ALS2 ALS2 SH3RF1 SH3RF1 PALLD PALLD CIB1 CIB1 FAT1 FAT1 PLCE1 PLCE1 RAPGEF3 RAPGEF3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RUFY3RUN and FYVE domain containing 3. (567 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1256 aa)
ARPC3Actin related protein 2/3 complex subunit 3. (178 aa)
SHTN1Shootin 1. (612 aa)
SPATA13Uncharacterized protein. (1148 aa)
STX3Syntaxin 3; Belongs to the syntaxin family. (290 aa)
ACTN1Actinin alpha 1. (830 aa)
CDC42Cell division cycle 42. (231 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (790 aa)
ACTR3Actin related protein 3; Belongs to the actin family. (418 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
LIMK1LIM domain kinase 1. (632 aa)
MYO10Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2017 aa)
SNX2Sorting nexin 2. (519 aa)
BRK1Uncharacterized protein. (90 aa)
PKN2Protein kinase N2. (983 aa)
ILKIntegrin linked kinase. (452 aa)
WASF1WASP family member 1. (559 aa)
APBB1Amyloid beta precursor protein binding family B member 1. (705 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (480 aa)
CARMIL3Capping protein regulator and myosin 1 linker 3. (1369 aa)
ABITRAMActin binding transcription modulator. (198 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (796 aa)
CFL1Cofilin 1; Belongs to the actin-binding proteins ADF family. (226 aa)
RAC3Rac family small GTPase 3. (189 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
ACTG2Actin gamma 2, smooth muscle; Belongs to the actin family. (376 aa)
FAM89BFamily with sequence similarity 89 member B. (192 aa)
CARMIL2Capping protein regulator and myosin 1 linker 2. (1447 aa)
P4HBProtein disulfide-isomerase. (510 aa)
DBNLDrebrin like. (408 aa)
STMN2Stathmin 2. (212 aa)
PDLIM4PDZ and LIM domain 4. (366 aa)
MYO1GMyosin IG; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1013 aa)
VILLVillin like. (855 aa)
CDC42BPBCDC42 binding protein kinase beta; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1715 aa)
RHOBRas homolog family member B. (196 aa)
KCNA2Potassium voltage-gated channel subfamily A member 2; Belongs to the potassium channel family. (499 aa)
KCNA1Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family. (495 aa)
ARHGAP31Rho GTPase activating protein 31. (1444 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1353 aa)
RAC1Rac family small GTPase 1. (198 aa)
DGKZDiacylglycerol kinase. (1124 aa)
G1LJH1_AILMEUncharacterized protein. (174 aa)
FSCN1Fascin. (485 aa)
VAMP7Vesicle associated membrane protein 7; Belongs to the synaptobrevin family. (220 aa)
UNC5CUnc-5 netrin receptor C. (931 aa)
G1LH72_AILMEUncharacterized protein. (186 aa)
G1LGV4_AILMEPodocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family. (453 aa)
PLEKHH2Pleckstrin homology, MyTH4 and FERM domain containing H2. (1493 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1259 aa)
PAK1Non-specific serine/threonine protein kinase. (551 aa)
DPP4Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (766 aa)
ABLIM3Actin binding LIM protein family member 3. (722 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (894 aa)
ACTC1Actin alpha cardiac muscle 1; Belongs to the actin family. (377 aa)
ABI3ABI family member 3. (453 aa)
IGF2BP1Insulin like growth factor 2 mRNA binding protein 1. (597 aa)
MYLKMyosin light chain kinase. (1914 aa)
FSCN3Fascin. (497 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (470 aa)
WASLWASP like actin nucleation promoting factor. (499 aa)
PLXND1Plexin D1. (1758 aa)
AMOTAngiomotin. (1066 aa)
STX2Syntaxin 2; Belongs to the syntaxin family. (288 aa)
TSC1TSC complex subunit 1. (1167 aa)
CORO6Coronin; Belongs to the WD repeat coronin family. (500 aa)
G1LBQ0_AILMEUncharacterized protein. (236 aa)
SYNE2KASH domain-containing protein. (6616 aa)
G1LBN4_AILMEIntegrin_alpha2 domain-containing protein. (453 aa)
CCDC88ACoiled-coil domain containing 88A. (1874 aa)
RHOCRas homolog family member C. (193 aa)
G1L9K7_AILMEUncharacterized protein. (659 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (971 aa)
DPYSL3Dihydropyrimidinase like 3. (571 aa)
VIL1Villin 1. (827 aa)
ARHGEF6Rac/Cdc42 guanine nucleotide exchange factor 6. (855 aa)
G1L7E7_AILMEClat_adaptor_s domain-containing protein. (286 aa)
FGD1FYVE, RhoGEF and PH domain containing 1. (917 aa)
SNX1Sorting nexin 1. (520 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (154 aa)
MYH10Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2018 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (271 aa)
CAPGCapping actin protein, gelsolin like. (349 aa)
ABI1Abl interactor 1. (509 aa)
WASF3WASP family member 3. (506 aa)
IQGAP2IQ motif containing GTPase activating protein 2. (1606 aa)
VASPVasodilator stimulated phosphoprotein. (330 aa)
GSNGelsolin. (773 aa)
ACTA2Actin alpha 2, smooth muscle; Belongs to the actin family. (377 aa)
CORO1BCoronin; Belongs to the WD repeat coronin family. (488 aa)
SLC39A6Solute carrier family 39 member 6. (735 aa)
PIP5K1APhosphatidylinositol-4-phosphate 5-kinase type 1 alpha. (562 aa)
TTNUncharacterized protein. (32000 aa)
G1L1A9_AILMEUncharacterized protein. (190 aa)
PABPC1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (636 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1011 aa)
AJUBAAjuba LIM protein. (546 aa)
CTTNCortactin. (544 aa)
G1LLP6_AILMEUncharacterized protein. (213 aa)
CD44CD44 molecule (Indian blood group). (762 aa)
NME1-NME2Nucleoside diphosphate kinase. (290 aa)
NF2Neurofibromin 2. (596 aa)
KPTNKaptin, actin binding protein. (436 aa)
CAPRIN1Cell cycle associated protein 1. (712 aa)
ITGAVIntegrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (576 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (200 aa)
CLRN1Clarin 1. (232 aa)
ACTA1Actin alpha 1, skeletal muscle. (374 aa)
GDPD2Glycerophosphodiester phosphodiesterase domain containing 2. (590 aa)
AIF1Allograft inflammatory factor 1. (159 aa)
PLCG1Phosphoinositide phospholipase C. (1294 aa)
CIB3Calcium and integrin binding family member 3. (187 aa)
RAC2Rac family small GTPase 2. (192 aa)
CARMIL1Capping protein regulator and myosin 1 linker 1. (1362 aa)
SH3BP1Uncharacterized protein. (703 aa)
PDXPUncharacterized protein. (150 aa)
SPEF1Sperm flagellar 1. (236 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
WASF2WASP family member 2. (496 aa)
SCYL3SCY1 like pseudokinase 3. (745 aa)
EVLEnah/Vasp-like. (425 aa)
PHACTR4Phosphatase and actin regulator. (712 aa)
EPHA2EPH receptor A2. (971 aa)
HAX1HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (283 aa)
RAB13Uncharacterized protein. (238 aa)
PPP1R9BProtein phosphatase 1 regulatory subunit 9B. (683 aa)
NGFRNerve growth factor receptor. (427 aa)
DAG1Dystroglycan 1. (892 aa)
RHOARas homolog family member A. (193 aa)
APCAPC regulator of WNT signaling pathway. (2848 aa)
G1M284_AILMEDeath domain-containing protein. (229 aa)
ABI2Abl interactor 2. (513 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (428 aa)
ACTR3BUncharacterized protein; Belongs to the actin family. (419 aa)
ALS2Alsin Rho guanine nucleotide exchange factor ALS2. (1662 aa)
SH3RF1SH3 domain containing ring finger 1. (880 aa)
PALLDPalladin, cytoskeletal associated protein. (1107 aa)
CIB1Calcium and integrin binding 1. (176 aa)
FAT1FAT atypical cadherin 1. (4590 aa)
PLCE1Phosphoinositide phospholipase C. (2303 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (930 aa)
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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