STRINGSTRING
LPXN LPXN HRG HRG NCKAP1L NCKAP1L LYN LYN NEXMIF NEXMIF ACER2 ACER2 SWAP70 SWAP70 ADA ADA SKAP1 SKAP1 G1LE75_AILME G1LE75_AILME LOC100480284 LOC100480284 G1LGV4_AILME G1LGV4_AILME CCL21 CCL21 JAM3 JAM3 LIF LIF CRK CRK ITGB1BP1 ITGB1BP1 PTPN11 PTPN11 CRKL CRKL SNAI2 SNAI2 FERMT1 FERMT1 TGFB2 TGFB2 G1LXT4_AILME G1LXT4_AILME EFNA1 EFNA1 EPHA2 EPHA2 TESC TESC CD3E CD3E CIB1 CIB1 PTPN6 PTPN6 EPHA8 EPHA8 ADAM9 ADAM9 PLAU PLAU RET RET LRRC45 LRRC45 SYK SYK CYP1B1 CYP1B1 FERMT3 FERMT3 SFRP2 SFRP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LPXNLeupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (391 aa)
HRGHistidine rich glycoprotein. (535 aa)
NCKAP1LNCK associated protein 1 like. (1137 aa)
LYNTyrosine-protein kinase. (512 aa)
NEXMIFNeurite extension and migration factor. (1514 aa)
ACER2Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
SWAP70Switching B cell complex subunit SWAP70. (587 aa)
ADAAdenosine deaminase. (363 aa)
SKAP1Src kinase associated phosphoprotein 1. (265 aa)
G1LE75_AILMEUncharacterized protein. (99 aa)
LOC100480284Uncharacterized protein. (325 aa)
G1LGV4_AILMEPodocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family. (453 aa)
CCL21C-C motif chemokine ligand 21. (137 aa)
JAM3Junctional adhesion molecule 3. (329 aa)
LIFLIF interleukin 6 family cytokine. (202 aa)
CRKCRK proto-oncogene, adaptor protein. (303 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (200 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
FERMT1Fermitin family member 1. (677 aa)
TGFB2Transforming growth factor beta 2. (442 aa)
G1LXT4_AILMESEA domain-containing protein. (275 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (205 aa)
EPHA2EPH receptor A2. (971 aa)
TESCTescalcin. (195 aa)
CD3ECD3e molecule. (201 aa)
CIB1Calcium and integrin binding 1. (176 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (613 aa)
EPHA8EPH receptor A8. (1025 aa)
ADAM9ADAM metallopeptidase domain 9. (843 aa)
PLAUPlasminogen activator, urokinase; Belongs to the peptidase S1 family. (432 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1121 aa)
LRRC45Leucine rich repeat containing 45. (670 aa)
SYKTyrosine-protein kinase. (630 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (539 aa)
FERMT3Fermitin family member 3. (634 aa)
SFRP2Secreted frizzled related protein 2. (301 aa)
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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