STRINGSTRING
FBXO17 FBXO17 GBA GBA PBK PBK CUL4B CUL4B DCAF12 DCAF12 NSFL1C NSFL1C ANKRD46 ANKRD46 PRAME PRAME UBE2J1 UBE2J1 FEM1C FEM1C FAM8A1 FAM8A1 PSMD4 PSMD4 DNAJB14 DNAJB14 FBXO38 FBXO38 PELI1 PELI1 ZNRF1 ZNRF1 DTL DTL FBXL17 FBXL17 FBXL5 FBXL5 UBXN8 UBXN8 CDC20 CDC20 PSMC1 PSMC1 G1L568_AILME G1L568_AILME UBE2G2 UBE2G2 USP44 USP44 ANKZF1 ANKZF1 FBXL22 FBXL22 FBXL2 FBXL2 TRIM71 TRIM71 RNF5 RNF5 ZFAND2B ZFAND2B FAM89A FAM89A TRIP4 TRIP4 SMURF2 SMURF2 SPOPL SPOPL WWP1 WWP1 TRIM25 TRIM25 JKAMP JKAMP RNF126 RNF126 UBXN2A UBXN2A G1L831_AILME G1L831_AILME CUL1 CUL1 UBE2K UBE2K PSMC5 PSMC5 G1L8Y5_AILME G1L8Y5_AILME G1L923_AILME G1L923_AILME CCDC47 CCDC47 HERC2 HERC2 YOD1 YOD1 MAN1A1 MAN1A1 LOC100473592 LOC100473592 FBXO45 FBXO45 UBE2S UBE2S PCNP PCNP UBXN7 UBXN7 MARCHF6 MARCHF6 TOPORS TOPORS FBXO33 FBXO33 SPSB1 SPSB1 FBXL20 FBXL20 G1LBY4_AILME G1LBY4_AILME ERCC8 ERCC8 UBE4B UBE4B CDC16 CDC16 SEC61B SEC61B PSMB3 PSMB3 G1LCP0_AILME G1LCP0_AILME ERLEC1 ERLEC1 AKIRIN2 AKIRIN2 TBX21 TBX21 PSMA5 PSMA5 HECW2 HECW2 FBXO48 FBXO48 DDIT3 DDIT3 HUWE1 HUWE1 GID4 GID4 TNFAIP1 TNFAIP1 PSMC6 PSMC6 OS9 OS9 SGTA SGTA UBE2H UBE2H KLHDC10 KLHDC10 PLAA PLAA FZR1 FZR1 FBXO9 FBXO9 FBXL6 FBXL6 DERL2 DERL2 SHARPIN SHARPIN UBXN2B UBXN2B ARMC8 ARMC8 RMND5B RMND5B DERL1 DERL1 FBXL18 FBXL18 HSP90B1 HSP90B1 ZNRF2 ZNRF2 RNF216 RNF216 PSMD7 PSMD7 WWP2 WWP2 USP14 USP14 SMURF1 SMURF1 UBE3D UBE3D ERLIN1 ERLIN1 FAF2 FAF2 SELENOS SELENOS TRIM72 TRIM72 TMEM67 TMEM67 RNF185 RNF185 FBXO39 FBXO39 STUB1 STUB1 FBXL16 FBXL16 PSMB5 PSMB5 PSMC3 PSMC3 CUL2 CUL2 ENSAMEP00000008362 ENSAMEP00000008362 PANDA_022450 PANDA_022450 FBXL3 FBXL3 ASCC2 ASCC2 APPBP2 APPBP2 LTN1 LTN1 SPSB3 SPSB3 RNF122 RNF122 NCCRP1 NCCRP1 G1LQ33_AILME G1LQ33_AILME SIAH2 SIAH2 SIRT2 SIRT2 CANX CANX AMN1 AMN1 KCTD2 KCTD2 G1LRD5_AILME G1LRD5_AILME ITCH ITCH PML PML BAG6 BAG6 HECW1 HECW1 CDC20B CDC20B KLHDC1 KLHDC1 KLHDC2 KLHDC2 FOXRED2 FOXRED2 TRPC4AP TRPC4AP EDEM2 EDEM2 FBXO2 FBXO2 NEMF NEMF FBXO6 FBXO6 DNAJC10 DNAJC10 STT3B STT3B FBXL7 FBXL7 KCTD17 KCTD17 RNF103 RNF103 RMND5A RMND5A CALR3 CALR3 TRIM9 TRIM9 CUL4A CUL4A SIAH1 SIAH1 PSMD8 PSMD8 WWTR1 WWTR1 UBR3 UBR3 G1LVD2_AILME G1LVD2_AILME UBXN11 UBXN11 RNF121 RNF121 WFS1 WFS1 CLGN CLGN ERLIN2 ERLIN2 RHBDD2 RHBDD2 FBXW11 FBXW11 KLHL22 KLHL22 CYSTM1 CYSTM1 BFAR BFAR SGTB SGTB FBXL4 FBXL4 DNAJC18 DNAJC18 UFD1 UFD1 HACE1 HACE1 KLHL42 KLHL42 FBXO42 FBXO42 DMAC2 DMAC2 CUL3 CUL3 NFE2L2 NFE2L2 FBXW9 FBXW9 SPOP SPOP SKP2 SKP2 FBXL12 FBXL12 PSMD14 PSMD14 RAD23A RAD23A UBE2C UBE2C KIF14 KIF14 PSMC4 PSMC4 KLHDC3 KLHDC3 KLHL15 KLHL15 USP19 USP19 FBXL13 FBXL13 UBR2 UBR2 CDC26 CDC26 SIAH3 SIAH3 UBE4A UBE4A ECRG4 ECRG4 FBXW5 FBXW5 HECTD3 HECTD3 EDEM3 EDEM3 UBE2J2 UBE2J2 TMUB1 TMUB1 DERL3 DERL3 SPSB2 SPSB2 ANAPC7 ANAPC7 RBCK1 RBCK1 CMIP CMIP FEM1B FEM1B PSMF1 PSMF1 ANAPC5 ANAPC5 RNF34 RNF34 RNF187 RNF187 RNF4 RNF4 UBE2G1 UBE2G1 CRBN CRBN RFFL RFFL CDC27 CDC27 ASCC3 ASCC3 UBXN4 UBXN4 KCTD13 KCTD13 UBE2U UBE2U NEDD4L NEDD4L PSMD6 PSMD6 PSMC2 PSMC2 ZFAND2A ZFAND2A TTC33 TTC33 VCP VCP FBXO41 FBXO41 KLHL20 KLHL20 UBR1 UBR1 HECTD1 HECTD1 ASB2 ASB2 FBXO4 FBXO4 PRKN PRKN PANDA_009467 PANDA_009467 G1MBM7_AILME G1MBM7_AILME WDR26 WDR26 EDEM1 EDEM1 NHLRC3 NHLRC3 ANAPC1 ANAPC1 TRIM3 TRIM3 PSMD1 PSMD1 SPSB4 SPSB4 DCAF11 DCAF11 CDC23 CDC23 DDB1 DDB1 ANAPC10 ANAPC10 HSPA5 HSPA5 TRIP12 TRIP12 KCTD10 KCTD10 AMFR AMFR DNAJB2 DNAJB2 ZSWIM8 ZSWIM8 CUL5 CUL5 HERPUD1 HERPUD1 MAEA MAEA TMEM129 TMEM129 RAD23B RAD23B MTM1 MTM1 COP1 COP1 PSMD2 PSMD2 AUP1 AUP1 FBXL8 FBXL8 LRRC29 LRRC29 G1MG10_AILME G1MG10_AILME GID8 GID8 KAT5 KAT5 DNAJB12 DNAJB12 ANAPC11 ANAPC11 FAF1 FAF1 G1MGR2_AILME G1MGR2_AILME BTRC BTRC FBXW4 FBXW4 SYVN1 SYVN1 FBXL15 FBXL15 SKP1 SKP1 UBE2B UBE2B CCNF CCNF ECPAS ECPAS ANAPC4 ANAPC4 SIRT1 SIRT1 DNAJB9 DNAJB9 G1MIR2_AILME G1MIR2_AILME FBXO31 FBXO31 GSE1 GSE1 AREL1 AREL1 TMUB2 TMUB2 NEDD4 NEDD4 PSMD12 PSMD12 FBXW7 FBXW7 RNF175 RNF175 ENSAMEP00000019523 ENSAMEP00000019523 FBXL14 FBXL14 DCAF12L2 DCAF12L2 KBTBD6 KBTBD6 KBTBD7 KBTBD7 RNF186 RNF186 UBXN10 UBXN10 G1MLC9_AILME G1MLC9_AILME TRIM13 TRIM13 LOC100470415 LOC100470415
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FBXO17F-box protein 17. (277 aa)
GBAGlucosylceramidase. (536 aa)
PBKPDZ binding kinase. (323 aa)
CUL4BCullin 4B; Belongs to the cullin family. (934 aa)
DCAF12DDB1 and CUL4 associated factor 12. (453 aa)
NSFL1CNSFL1 cofactor. (374 aa)
ANKRD46Ankyrin repeat domain 46. (228 aa)
PRAMEPreferentially expressed antigen in melanoma. (494 aa)
UBE2J1Ubiquitin conjugating enzyme E2 J1. (318 aa)
FEM1CFem-1 homolog C. (617 aa)
FAM8A1Family with sequence similarity 8 member A1. (225 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (377 aa)
DNAJB14DnaJ heat shock protein family (Hsp40) member B14. (379 aa)
FBXO38F-box protein 38. (1190 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
ZNRF1Zinc and ring finger 1. (269 aa)
DTLDenticleless E3 ubiquitin protein ligase homolog. (730 aa)
FBXL17F-box and leucine rich repeat protein 17. (371 aa)
FBXL5F-box and leucine rich repeat protein 5. (674 aa)
UBXN8UBX domain protein 8. (278 aa)
CDC20Cell division cycle 20. (499 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
G1L568_AILMEUBIQUITIN_CONJUGAT_2 domain-containing protein. (184 aa)
UBE2G2Ubiquitin conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family. (165 aa)
USP44Ubiquitin carboxyl-terminal hydrolase 44; Deubiquitinase that plays a key regulatory role in the spindle assembly checkpoint or mitotic checkpoint by preventing premature anaphase onset. Acts by specifically mediating deubiquitination of CDC20, a negative regulator of the anaphase promoting complex/cyclosome (APC/C). Deubiquitination of CDC20 leads to stabilize the MAD2L1-CDC20-APC/C ternary complex (also named mitotic checkpoint complex), thereby preventing premature activation of the APC/C. Promotes association of MAD2L1 with CDC20 and reinforces the spindle assembly checkpoint. Acts [...] (711 aa)
ANKZF1Ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1. (760 aa)
FBXL22Uncharacterized protein. (142 aa)
FBXL2F-box and leucine rich repeat protein 2. (422 aa)
TRIM71Tripartite motif containing 71. (603 aa)
RNF5Ring finger protein 5. (182 aa)
ZFAND2BZinc finger AN1-type containing 2B. (261 aa)
FAM89AFamily with sequence similarity 89 member A. (111 aa)
TRIP4Thyroid hormone receptor interactor 4. (581 aa)
SMURF2E3 ubiquitin-protein ligase. (735 aa)
SPOPLSpeckle type BTB/POZ protein like. (392 aa)
WWP1E3 ubiquitin-protein ligase. (920 aa)
TRIM25Tripartite motif containing 25. (627 aa)
JKAMPJNK1/MAPK8 associated membrane protein. (311 aa)
RNF126Ring finger protein 126. (332 aa)
UBXN2AUBX domain protein 2A. (257 aa)
G1L831_AILMECULLIN_2 domain-containing protein; Belongs to the cullin family. (405 aa)
CUL1Cullin 1; Belongs to the cullin family. (777 aa)
UBE2KUbiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. (200 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (412 aa)
G1L8Y5_AILMEUncharacterized protein. (130 aa)
G1L923_AILMEUncharacterized protein; Belongs to the SKP1 family. (157 aa)
CCDC47Coiled-coil domain containing 47. (486 aa)
HERC2Uncharacterized protein. (3892 aa)
YOD1YOD1 deubiquitinase. (348 aa)
MAN1A1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (597 aa)
LOC100473592UBX domain-containing protein. (243 aa)
FBXO45F-box protein 45. (283 aa)
UBE2SUbiquitin conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (223 aa)
PCNPPEST proteolytic signal containing nuclear protein. (178 aa)
UBXN7UBX domain-containing protein 7. (469 aa)
MARCHF6Membrane associated ring-CH-type finger 6. (910 aa)
TOPORSTOP1 binding arginine/serine rich protein. (1043 aa)
FBXO33F-box protein 33. (501 aa)
SPSB1SplA/ryanodine receptor domain and SOCS box containing 1. (273 aa)
FBXL20F-box and leucine rich repeat protein 20. (436 aa)
G1LBY4_AILMEAAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
ERCC8ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (396 aa)
UBE4BUbiquitination factor E4B. (1362 aa)
CDC16Cell division cycle 16. (619 aa)
SEC61BSEC61 translocon beta subunit. (95 aa)
PSMB3Proteasome subunit beta. (205 aa)
G1LCP0_AILMEUncharacterized protein. (470 aa)
ERLEC1Endoplasmic reticulum lectin 1. (501 aa)
AKIRIN2Akirin 2. (204 aa)
TBX21T-box transcription factor 21. (439 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
HECW2HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2. (1572 aa)
FBXO48F-box protein 48. (155 aa)
DDIT3DNA damage inducible transcript 3. (168 aa)
HUWE1HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1. (4377 aa)
GID4GID complex subunit 4 homolog. (155 aa)
TNFAIP1TNF alpha induced protein 1. (320 aa)
PSMC6AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
OS9OS9 endoplasmic reticulum lectin. (669 aa)
SGTASmall glutamine rich tetratricopeptide repeat containing alpha. (313 aa)
UBE2HUbiquitin conjugating enzyme E2 H; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
KLHDC10Kelch domain containing 10. (389 aa)
PLAAPhospholipase A2 activating protein. (803 aa)
FZR1Fizzy and cell division cycle 20 related 1. (496 aa)
FBXO9F-box protein 9. (536 aa)
FBXL6F-box and leucine rich repeat protein 6. (521 aa)
DERL2Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa)
SHARPINSHANK associated RH domain interactor. (366 aa)
UBXN2BUBX domain protein 2B. (330 aa)
ARMC8Armadillo repeat containing 8. (673 aa)
RMND5BRequired for meiotic nuclear division 5 homolog B. (393 aa)
DERL1Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (251 aa)
FBXL18F-box and leucine rich repeat protein 18. (679 aa)
HSP90B1Heat shock protein 90 beta family member 1. (803 aa)
ZNRF2RING-type domain-containing protein. (105 aa)
RNF216Ring finger protein 216. (928 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (322 aa)
WWP2E3 ubiquitin-protein ligase. (872 aa)
USP14Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (494 aa)
SMURF1E3 ubiquitin-protein ligase. (753 aa)
UBE3DUbiquitin protein ligase E3D. (384 aa)
ERLIN1ER lipid raft associated 1. (348 aa)
FAF2Fas associated factor family member 2. (447 aa)
SELENOSSelenoprotein S. (188 aa)
TRIM72Tripartite motif containing 72. (481 aa)
TMEM67Transmembrane protein 67. (1003 aa)
RNF185Ring finger protein 185. (192 aa)
FBXO39F-box protein 39. (443 aa)
STUB1STIP1 homology and U-box containing protein 1. (250 aa)
FBXL16F-box and leucine rich repeat protein 16. (439 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSMC3Proteasome 26S subunit, ATPase 3. (491 aa)
CUL2Cullin 2; Belongs to the cullin family. (748 aa)
ENSAMEP00000008362annotation not available (300 aa)
PANDA_022450alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (178 aa)
FBXL3F-box and leucine rich repeat protein 3. (428 aa)
ASCC2Activating signal cointegrator 1 complex subunit 2. (753 aa)
APPBP2Amyloid beta precursor protein binding protein 2. (585 aa)
LTN1Listerin E3 ubiquitin protein ligase 1. (1780 aa)
SPSB3SplA/ryanodine receptor domain and SOCS box containing 3. (355 aa)
RNF122Ring finger protein 122. (155 aa)
NCCRP1Non-specific cytotoxic cell receptor protein 1 homolog (zebrafish). (210 aa)
G1LQ33_AILMEFBA domain-containing protein. (156 aa)
SIAH2E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (331 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (393 aa)
CANXCalnexin. (594 aa)
AMN1Antagonist of mitotic exit network 1 homolog. (260 aa)
KCTD2Potassium channel tetramerization domain containing 2. (253 aa)
G1LRD5_AILMEUncharacterized protein. (623 aa)
ITCHE3 ubiquitin-protein ligase. (873 aa)
PMLPromyelocytic leukemia. (880 aa)
BAG6BCL2 associated athanogene 6. (1164 aa)
HECW1HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1. (1376 aa)
CDC20BCell division cycle 20B. (517 aa)
KLHDC1Kelch domain containing 1. (406 aa)
KLHDC2Kelch domain containing 2. (360 aa)
FOXRED2FAD dependent oxidoreductase domain containing 2. (688 aa)
TRPC4APTransient receptor potential cation channel subfamily C member 4 associated protein. (816 aa)
EDEM2alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (578 aa)
FBXO2F-box protein 2. (294 aa)
NEMFNuclear export mediator factor. (1077 aa)
FBXO6F-box protein 6. (293 aa)
DNAJC10DnaJ homolog subfamily C member 10; Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. (796 aa)
STT3BSTT3 oligosaccharyltransferase complex catalytic subunit B. (721 aa)
FBXL7F-box and leucine rich repeat protein 7. (449 aa)
KCTD17Potassium channel tetramerization domain containing 17. (235 aa)
RNF103Ring finger protein 103. (685 aa)
RMND5ARequired for meiotic nuclear division 5 homolog A. (391 aa)
CALR3Calreticulin. (385 aa)
TRIM9Tripartite motif containing 9. (519 aa)
CUL4ACullin 4A; Belongs to the cullin family. (723 aa)
SIAH1E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (313 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (348 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
UBR3E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (678 aa)
G1LVD2_AILMEE3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (315 aa)
UBXN11UBX domain protein 11. (522 aa)
RNF121Ring finger protein 121. (327 aa)
WFS1Wolframin ER transmembrane glycoprotein. (888 aa)
CLGNCalmegin. (613 aa)
ERLIN2ER lipid raft associated 2. (338 aa)
RHBDD2Rhomboid domain containing 2. (364 aa)
FBXW11F-box and WD repeat domain containing 11. (542 aa)
KLHL22Kelch-like protein 22; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for chromosome alignment and localization of PLK1 at kinetochores. The BCR(KLHL22) ubiquitin ligase complex mediates monoubiquitination of PLK1, leading to PLK1 dissociation from phosphoreceptor proteins and subsequent removal from kinetochores, allowing silencing of the spindle assembly checkpoint (SAC) and chromosome segregation. Monoubiquitination of PLK1 does not lead to PLK1 degradation. The BCR(KLHL22) ubiquitin ligase complex is also responsible for the amino acid-stim [...] (634 aa)
CYSTM1Cysteine rich transmembrane module containing 1. (102 aa)
BFARBifunctional apoptosis regulator. (450 aa)
SGTBSmall glutamine rich tetratricopeptide repeat containing beta. (304 aa)
FBXL4F-box and leucine rich repeat protein 4. (621 aa)
DNAJC18DnaJ heat shock protein family (Hsp40) member C18. (347 aa)
UFD1Ubiquitin recognition factor in ER associated degradation 1. (306 aa)
HACE1HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1. (912 aa)
KLHL42Kelch like family member 42. (517 aa)
FBXO42F-box protein 42. (717 aa)
DMAC2Distal membrane arm assembly complex 2. (323 aa)
CUL3Cullin 3; Belongs to the cullin family. (791 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (610 aa)
FBXW9F-box and WD repeat domain containing 9. (453 aa)
SPOPSpeckle type BTB/POZ protein. (393 aa)
SKP2S-phase kinase associated protein 2. (424 aa)
FBXL12F-box and leucine rich repeat protein 12. (326 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
RAD23ARAD23 homolog A, nucleotide excision repair protein. (380 aa)
UBE2CUbiquitin conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (181 aa)
KIF14Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1648 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
KLHDC3Kelch domain containing 3. (550 aa)
KLHL15Kelch like family member 15. (604 aa)
USP19Ubiquitin specific peptidase 19. (1434 aa)
FBXL13F-box and leucine rich repeat protein 13. (767 aa)
UBR2E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1651 aa)
CDC26Cell division cycle 26. (85 aa)
SIAH3E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (267 aa)
UBE4AUbiquitination factor E4A. (1074 aa)
ECRG4ECRG4 augurin precursor. (147 aa)
FBXW5F-box and WD repeat domain containing 5. (567 aa)
HECTD3HECT domain E3 ubiquitin protein ligase 3. (861 aa)
EDEM3alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (932 aa)
UBE2J2Ubiquitin conjugating enzyme E2 J2. (259 aa)
TMUB1Transmembrane and ubiquitin like domain containing 1. (271 aa)
DERL3Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (231 aa)
SPSB2SplA/ryanodine receptor domain and SOCS box containing 2. (263 aa)
ANAPC7Anaphase promoting complex subunit 7. (597 aa)
RBCK1RANBP2-type and C3HC4-type zinc finger containing 1. (510 aa)
CMIPC-Maf inducing protein. (741 aa)
FEM1BFem-1 homolog B. (629 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
ANAPC5Anaphase promoting complex subunit 5. (756 aa)
RNF34Ring finger protein 34. (375 aa)
RNF187Uncharacterized protein. (106 aa)
RNF4Ring finger protein 4. (194 aa)
UBE2G1Ubiquitin conjugating enzyme E2 G1; Belongs to the ubiquitin-conjugating enzyme family. (170 aa)
CRBNCereblon. (445 aa)
RFFLRing finger and FYVE like domain containing E3 ubiquitin protein ligase. (374 aa)
CDC27Cell division cycle 27. (831 aa)
ASCC3Activating signal cointegrator 1 complex subunit 3. (2202 aa)
UBXN4Uncharacterized protein. (207 aa)
KCTD13Potassium channel tetramerization domain containing 13. (329 aa)
UBE2UUbiquitin conjugating enzyme E2 U. (202 aa)
NEDD4LE3 ubiquitin-protein ligase. (924 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (390 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (476 aa)
ZFAND2AZinc finger AN1-type containing 2A. (176 aa)
TTC33Tetratricopeptide repeat domain 33. (262 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
FBXO41F-box protein 41. (702 aa)
KLHL20Kelch like family member 20. (609 aa)
UBR1E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1753 aa)
HECTD1HECT domain E3 ubiquitin protein ligase 1. (2610 aa)
ASB2Ankyrin repeat and SOCS box containing 2. (632 aa)
FBXO4F-box protein 4. (387 aa)
PRKNUbiquitin-like domain-containing protein. (287 aa)
PANDA_009467zf-RING_14 domain-containing protein. (74 aa)
G1MBM7_AILMERBR-type E3 ubiquitin transferase. (105 aa)
WDR26WD repeat domain 26. (576 aa)
EDEM1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (591 aa)
NHLRC3NHL repeat containing 3. (347 aa)
ANAPC1Anaphase promoting complex subunit 1. (1948 aa)
TRIM3Tripartite motif containing 3. (744 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
SPSB4SplA/ryanodine receptor domain and SOCS box containing 4. (273 aa)
DCAF11DDB1 and CUL4 associated factor 11. (546 aa)
CDC23Cell division cycle 23. (597 aa)
DDB1Damage specific DNA binding protein 1. (1140 aa)
ANAPC10DOC domain-containing protein. (185 aa)
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (655 aa)
TRIP12Thyroid hormone receptor interactor 12. (2040 aa)
KCTD10Potassium channel tetramerization domain containing 10. (316 aa)
AMFRAutocrine motility factor receptor. (560 aa)
DNAJB2DnaJ heat shock protein family (Hsp40) member B2. (325 aa)
ZSWIM8Zinc finger SWIM-type containing 8. (1884 aa)
CUL5Cullin 5; Belongs to the cullin family. (780 aa)
HERPUD1Homocysteine inducible ER protein with ubiquitin like domain 1. (417 aa)
MAEAMacrophage erythroblast attacher. (413 aa)
TMEM129Transmembrane protein 129. (362 aa)
RAD23BRAD23 homolog B, nucleotide excision repair protein. (410 aa)
MTM1Myotubularin 1. (455 aa)
COP1COP1 E3 ubiquitin ligase. (620 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (913 aa)
AUP1AUP1 lipid droplet regulating VLDL assembly factor. (465 aa)
FBXL8F-box domain-containing protein. (379 aa)
LRRC29Leucine rich repeat containing 29. (286 aa)
G1MG10_AILMEF-box domain-containing protein. (174 aa)
GID8GID complex subunit 8 homolog. (229 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa)
DNAJB12DnaJ heat shock protein family (Hsp40) member B12. (409 aa)
ANAPC11RING-type domain-containing protein. (84 aa)
FAF1Fas associated factor 1. (649 aa)
G1MGR2_AILMEUncharacterized protein. (287 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
FBXW4F-box and WD repeat domain containing 4. (411 aa)
SYVN1Synoviolin 1. (609 aa)
FBXL15F-box and leucine rich repeat protein 15. (297 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
UBE2BUbiquitin conjugating enzyme E2 B; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
CCNFCyclin F; Belongs to the cyclin family. (785 aa)
ECPASEcm29 proteasome adaptor and scaffold. (1845 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (810 aa)
SIRT1Sirtuin 1. (607 aa)
DNAJB9DnaJ heat shock protein family (Hsp40) member B9. (222 aa)
G1MIR2_AILMEUncharacterized protein. (118 aa)
FBXO31F-box protein 31. (516 aa)
GSE1Gse1 coiled-coil protein. (1205 aa)
AREL1Apoptosis resistant E3 ubiquitin protein ligase 1. (823 aa)
TMUB2Transmembrane and ubiquitin like domain containing 2. (320 aa)
NEDD4NEDD4 E3 ubiquitin protein ligase. (1321 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
FBXW7F-box and WD repeat domain containing 7. (708 aa)
RNF175Ring finger protein 175. (320 aa)
ENSAMEP00000019523annotation not available (197 aa)
FBXL14F-box and leucine rich repeat protein 14. (400 aa)
DCAF12L2DDB1 and CUL4 associated factor 12 like 2. (426 aa)
KBTBD6Kelch repeat and BTB domain containing 6. (699 aa)
KBTBD7Kelch repeat and BTB domain containing 7. (679 aa)
RNF186Ring finger protein 186. (258 aa)
UBXN10UBX domain protein 10. (281 aa)
G1MLC9_AILMERING-type domain-containing protein. (189 aa)
TRIM13Tripartite motif containing 13. (409 aa)
LOC100470415E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (282 aa)
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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