(69 nodes) Negative regulation of ion transport network (Ailuropoda melanoleuca)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	SYT11	Synaptotagmin 11. (436 aa)
	PTK2B	Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1011 aa)
	HAMP	Hepcidin antimicrobial peptide. (83 aa)
	SESTD1	SEC14 and spectrin domain containing 1. (697 aa)
	SLC30A1	Solute carrier family 30 member 1. (505 aa)
	ACTN2	Actinin alpha 2. (896 aa)
	SRI	Sorcin. (194 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
	GABRE	Gamma-aminobutyric acid type A receptor epsilon subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (500 aa)
	WNK3	Protein kinase domain-containing protein. (442 aa)
	G1L7E0_AILME	Uncharacterized protein. (383 aa)
	OSR1	Odd-skipped related transcription factor 1. (267 aa)
	FKBP1B	Peptidylprolyl isomerase. (103 aa)
	PKD2	Polycystin 2, transient receptor potential cation channel. (971 aa)
	TRH	Thyrotropin releasing hormone. (242 aa)
	WNK1	WNK lysine deficient protein kinase 1. (2388 aa)
	KCNRG	Potassium channel regulator. (271 aa)
	HECW2	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2. (1572 aa)
	DRD3	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (447 aa)
	GOPC	PDZ domain-containing protein. (465 aa)
	GEM	GTP binding protein overexpressed in skeletal muscle. (296 aa)
	G1LHT7_AILME	Uncharacterized protein. (1112 aa)
	CALM2	Calmodulin 2. (148 aa)
	KEL	Kell metallo-endopeptidase (Kell blood group). (736 aa)
	G1LJC6_AILME	Uncharacterized protein. (226 aa)
	WNK4	WNK lysine deficient protein kinase 4. (1556 aa)
	GNB5	G protein subunit beta 5. (395 aa)
	PACSIN3	Protein kinase C and casein kinase substrate in neurons 3. (481 aa)
	REM2	RRAD and GEM like GTPase 2. (333 aa)
	SLC43A2	Solute carrier family 43 member 2. (598 aa)
	INPP5K	Inositol polyphosphate-5-phosphatase K. (468 aa)
	CALM3	Calmodulin 3; Belongs to the calmodulin family. (150 aa)
	CLIC2	Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (246 aa)
	HECW1	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1. (1376 aa)
	ARL6IP5	PRA1 family protein. (188 aa)
	ANO9	Anoctamin. (752 aa)
	G1LVG1_AILME	G_PROTEIN_RECEP_F1_2 domain-containing protein. (214 aa)
	VIP	Vasoactive intestinal peptide. (170 aa)
	CASQ2	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (416 aa)
	STK39	Serine/threonine kinase 39. (477 aa)
	G1LYS5_AILME	Uncharacterized protein; Belongs to the calmodulin family. (133 aa)
	SERPINE2	Serpin family E member 2; Belongs to the serpin family. (410 aa)
	PXK	PX domain containing serine/threonine kinase like. (547 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (154 aa)
	PPIF	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (211 aa)
	SUMO1	Small ubiquitin-related modifier. (98 aa)
	PAWR	Pro-apoptotic WT1 regulator. (217 aa)
	HRH3	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (227 aa)
	REM1	GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (299 aa)
	TRIM27	Tripartite motif containing 27. (563 aa)
	KCNH2	Potassium voltage-gated channel subfamily H member 2. (1092 aa)
	SFRP4	Secreted frizzled related protein 4. (348 aa)
	SLC43A1	Solute carrier family 43 member 1. (564 aa)
	CRBN	Cereblon. (445 aa)
	NEDD4L	E3 ubiquitin-protein ligase. (924 aa)
	GRP	Gastrin releasing peptide. (134 aa)
	GPM6B	Glycoprotein M6B. (328 aa)
	RRAD	GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (278 aa)
	G1MGQ8_AILME	Uncharacterized protein; Belongs to the calmodulin family. (142 aa)
	OXSR1	Oxidative stress responsive kinase 1. (527 aa)
	NEDD4	NEDD4 E3 ubiquitin protein ligase. (1321 aa)
	KCNE4	Potassium voltage-gated channel subfamily E regulatory subunit 4. (170 aa)
	KCNE1	Uncharacterized protein. (129 aa)
	PLN	Phospholamban. (52 aa)
	KCNE5	Potassium voltage-gated channel subfamily E regulatory subunit 5. (89 aa)
	KCNE2	Potassium voltage-gated channel subfamily E regulatory subunit 2. (123 aa)
	LOC100484770	Uncharacterized protein; Belongs to the calmodulin family. (149 aa)
	CUNH4orf3	Uncharacterized protein. (68 aa)
	KCNE3	Potassium voltage-gated channel subfamily E regulatory subunit 3. (99 aa)

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTN2	CASQ2	ENSAMEP00000001254	ENSAMEP00000011441	Actinin alpha 2.	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	0.506
ACTN2	CAV3	ENSAMEP00000001254	ENSAMEP00000013002	Actinin alpha 2.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.498
ACTN2	PLN	ENSAMEP00000001254	ENSAMEP00000019897	Actinin alpha 2.	Phospholamban.	0.457
CALM2	CALM3	ENSAMEP00000006544	ENSAMEP00000009014	Calmodulin 2.	Calmodulin 3; Belongs to the calmodulin family.	0.801
CALM2	CAV1	ENSAMEP00000006544	ENSAMEP00000001406	Calmodulin 2.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.561
CALM2	FKBP1B	ENSAMEP00000006544	ENSAMEP00000002937	Calmodulin 2.	Peptidylprolyl isomerase.	0.846
CALM3	CALM2	ENSAMEP00000009014	ENSAMEP00000006544	Calmodulin 3; Belongs to the calmodulin family.	Calmodulin 2.	0.801
CALM3	CAV1	ENSAMEP00000009014	ENSAMEP00000001406	Calmodulin 3; Belongs to the calmodulin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.561
CALM3	FKBP1B	ENSAMEP00000009014	ENSAMEP00000002937	Calmodulin 3; Belongs to the calmodulin family.	Peptidylprolyl isomerase.	0.846
CASQ2	ACTN2	ENSAMEP00000011441	ENSAMEP00000001254	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Actinin alpha 2.	0.506
CASQ2	CAV3	ENSAMEP00000011441	ENSAMEP00000013002	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.413
CASQ2	FKBP1B	ENSAMEP00000011441	ENSAMEP00000002937	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Peptidylprolyl isomerase.	0.488
CASQ2	KCNH2	ENSAMEP00000011441	ENSAMEP00000014784	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Potassium voltage-gated channel subfamily H member 2.	0.586
CASQ2	PLN	ENSAMEP00000011441	ENSAMEP00000019897	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Phospholamban.	0.577
CASQ2	SRI	ENSAMEP00000011441	ENSAMEP00000001344	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Sorcin.	0.536
CAV1	CALM2	ENSAMEP00000001406	ENSAMEP00000006544	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Calmodulin 2.	0.561
CAV1	CALM3	ENSAMEP00000001406	ENSAMEP00000009014	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Calmodulin 3; Belongs to the calmodulin family.	0.561
CAV1	CAV3	ENSAMEP00000001406	ENSAMEP00000013002	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.954
CAV1	G1LYS5_AILME	ENSAMEP00000001406	ENSAMEP00000012232	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Uncharacterized protein; Belongs to the calmodulin family.	0.561
CAV1	G1MGQ8_AILME	ENSAMEP00000001406	ENSAMEP00000018542	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Uncharacterized protein; Belongs to the calmodulin family.	0.561