STRINGSTRING
PLEC PLEC JAM3 JAM3 TJP2 TJP2 RAMP2 RAMP2 SMAD7 SMAD7 FSCN1 FSCN1 CLDN18 CLDN18 CDH20 CDH20 CDH6 CDH6 TRPV4 TRPV4 TJP3 TJP3 WDR1 WDR1 JUP JUP CLDN9 CLDN9 G1LFE2_AILME G1LFE2_AILME CSF1R CSF1R SHROOM2 SHROOM2 CLDN11 CLDN11 PRKCI PRKCI KIRREL1 KIRREL1 CD177 CD177 PTPRO PTPRO PAK2 PAK2 G1LAL1_AILME G1LAL1_AILME DLG1 DLG1 RHOC RHOC GJA5 GJA5 CLDN8 CLDN8 GJC1 GJC1 RHOB RHOB CLDN5 CLDN5 CLDN25 CLDN25 CLDN22 CLDN22 CLDN20 CLDN20 PANDA_011714 PANDA_011714 CLDN4 CLDN4 CLDN3 CLDN3 CLDN14 CLDN14 GJB6 GJB6 CLDN2 CLDN2 F2R F2R TGFB3 TGFB3 NUMB NUMB SVEP1 SVEP1 CCM2 CCM2 DLG5 DLG5 ARL2 ARL2 PARD6A PARD6A DSP DSP G1MF40_AILME G1MF40_AILME CDH5 CDH5 WNT11 WNT11 CDH19 CDH19 CDH8 CDH8 VCL VCL CLDN7 CLDN7 CDH7 CDH7 PKN2 PKN2 MTSS1 MTSS1 FERMT2 FERMT2 NR1H4 NR1H4 G1M9K4_AILME G1M9K4_AILME G1M8C7_AILME G1M8C7_AILME CTNND1 CTNND1 CD9 CD9 SMAD3 SMAD3 OCLN OCLN MARVELD2 MARVELD2 HIPK1 HIPK1 TJP1 TJP1 ADAM10 ADAM10 PLEKHA7 PLEKHA7 PECAM1 PECAM1 EXT1 EXT1 GNPAT GNPAT FLCN FLCN CLDN19 CLDN19 F2RL1 F2RL1 CLDN15 CLDN15 CDH11 CDH11 TBCD TBCD ECT2 ECT2 G1L1Q9_AILME G1L1Q9_AILME ESAM ESAM NPHS1 NPHS1 CLDN1 CLDN1 EPB41L3 EPB41L3 CLDN23 CLDN23 GRHL2 GRHL2 LSR LSR LOC100468630 LOC100468630 UGT8 UGT8 CXADR CXADR ILDR1 ILDR1 GJB2 GJB2 CDH9 CDH9 G1M3N0_AILME G1M3N0_AILME LIMS1 LIMS1 CTNND2 CTNND2 POF1B POF1B CDH22 CDH22 RHOA RHOA INAVA INAVA WHRN WHRN SRF SRF NUMBL NUMBL PKP1 PKP1 RAB13 RAB13 LIMS2 LIMS2 PRKCA PRKCA PATJ PATJ ARVCF ARVCF TGFB1 TGFB1 CTNNB1 CTNNB1 CLDN16 CLDN16 GRHL1 GRHL1 TGFB2 TGFB2 CDH10 CDH10 PKP3 PKP3 OCEL1 OCEL1 G1LUU5_AILME G1LUU5_AILME CLDN10 CLDN10 FBF1 FBF1 SNAI2 SNAI2 G1LS85_AILME G1LS85_AILME PKP2 PKP2 CSK CSK DLG2 DLG2 G1LPZ3_AILME G1LPZ3_AILME PKHD1 PKHD1 CAMSAP3 CAMSAP3 MPP7 MPP7 NF2 NF2 CDH18 CDH18 EPHA4 EPHA4 CDH24 CDH24 FLNA FLNA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLECPlectin. (4622 aa)
JAM3Junctional adhesion molecule 3. (329 aa)
TJP2Uncharacterized protein; Belongs to the MAGUK family. (1233 aa)
RAMP2Receptor activity modifying protein 2. (177 aa)
SMAD7Mothers against decapentaplegic homolog. (427 aa)
FSCN1Fascin. (485 aa)
CLDN18Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (261 aa)
CDH20Cadherin 20; Cadherins are calcium-dependent cell adhesion proteins. (801 aa)
CDH6Cadherin 6; Cadherins are calcium-dependent cell adhesion proteins. (790 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (872 aa)
TJP3Tight junction protein 3; Belongs to the MAGUK family. (916 aa)
WDR1WD repeat domain 1. (624 aa)
JUPJunction plakoglobin. (779 aa)
CLDN9Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa)
G1LFE2_AILMEUncharacterized protein. (328 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (968 aa)
SHROOM2Shroom family member 2. (1409 aa)
CLDN11Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (207 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (524 aa)
KIRREL1Kirre like nephrin family adhesion molecule 1. (720 aa)
CD177CD177 molecule. (434 aa)
PTPROProtein tyrosine phosphatase receptor type O. (1206 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
G1LAL1_AILMEUncharacterized protein. (296 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (766 aa)
RHOCRas homolog family member C. (193 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
CLDN8Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (225 aa)
GJC1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (396 aa)
RHOBRas homolog family member B. (196 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
CLDN25Claudin 25. (228 aa)
CLDN22Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
CLDN20Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (219 aa)
PANDA_011714Uncharacterized protein. (124 aa)
CLDN4Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
CLDN3Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
CLDN14Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (237 aa)
GJB6Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (261 aa)
CLDN2Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (230 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (397 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (417 aa)
NUMBNUMB endocytic adaptor protein. (654 aa)
SVEP1Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1. (3492 aa)
CCM2CCM2 scaffold protein. (434 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1922 aa)
ARL2ARL2-SNX15 readthrough (NMD candidate); Belongs to the small GTPase superfamily. Arf family. (190 aa)
PARD6APar-6 family cell polarity regulator alpha. (346 aa)
DSPDesmoplakin. (2827 aa)
G1MF40_AILMEKIND domain-containing protein. (190 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (803 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
CDH19Cadherin 19; Cadherins are calcium-dependent cell adhesion proteins. (771 aa)
CDH8Cadherin 8; Cadherins are calcium-dependent cell adhesion proteins. (586 aa)
VCLVinculin. (1137 aa)
CLDN7Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
CDH7Cadherin 7; Cadherins are calcium-dependent cell adhesion proteins. (785 aa)
PKN2Protein kinase N2. (983 aa)
MTSS1MTSS I-BAR domain containing 1. (755 aa)
FERMT2Fermitin family member 2. (687 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (486 aa)
G1M9K4_AILMEUncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (404 aa)
G1M8C7_AILMELIM zinc-binding domain-containing protein. (117 aa)
CTNND1Catenin delta 1. (971 aa)
CD9Tetraspanin. (227 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
OCLNOccludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (520 aa)
MARVELD2MARVEL domain containing 2. (559 aa)
HIPK1Homeodomain interacting protein kinase 1. (1210 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1765 aa)
ADAM10ADAM metallopeptidase domain 10. (732 aa)
PLEKHA7Pleckstrin homology domain containing A7. (1202 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (746 aa)
EXT1Uncharacterized protein; Belongs to the glycosyltransferase 47 family. (427 aa)
GNPATDihydroxyacetone phosphate acyltransferase. (692 aa)
FLCNUDENN FLCN/SMCR8-type domain-containing protein. (579 aa)
CLDN19Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa)
F2RL1F2R like trypsin receptor 1. (401 aa)
CLDN15Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (173 aa)
CDH11Cadherin 11; Cadherins are calcium-dependent cell adhesion proteins. (798 aa)
TBCDTubulin folding cofactor D. (1167 aa)
ECT2Epithelial cell transforming 2. (927 aa)
G1L1Q9_AILMEIGv domain-containing protein. (145 aa)
ESAMUncharacterized protein. (393 aa)
NPHS1NPHS1 adhesion molecule, nephrin. (1260 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
EPB41L3Erythrocyte membrane protein band 4.1 like 3. (1106 aa)
CLDN23Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (184 aa)
GRHL2Grainyhead like transcription factor 2. (625 aa)
LSRLipolysis stimulated lipoprotein receptor. (648 aa)
LOC100468630Plakophilin 4. (638 aa)
UGT8UDP glycosyltransferase 8; Belongs to the UDP-glycosyltransferase family. (541 aa)
CXADRUncharacterized protein. (365 aa)
ILDR1Immunoglobulin like domain containing receptor 1. (551 aa)
GJB2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (286 aa)
CDH9Cadherin 9; Cadherins are calcium-dependent cell adhesion proteins. (789 aa)
G1M3N0_AILMEUncharacterized protein. (463 aa)
LIMS1LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (285 aa)
CTNND2Uncharacterized protein. (646 aa)
POF1BPOF1B actin binding protein. (596 aa)
CDH22Cadherin 22; Cadherins are calcium-dependent cell adhesion proteins. (637 aa)
RHOARas homolog family member A. (193 aa)
INAVAInnate immunity activator. (470 aa)
WHRNWhirlin. (887 aa)
SRFSerum response factor. (444 aa)
NUMBLNUMB like endocytic adaptor protein. (603 aa)
PKP1Plakophilin 1. (727 aa)
RAB13Uncharacterized protein. (238 aa)
LIMS2LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (342 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (666 aa)
PATJPATJ crumbs cell polarity complex component. (1841 aa)
ARVCFARVCF delta catenin family member. (957 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (355 aa)
CTNNB1Catenin beta 1. (781 aa)
CLDN16Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (301 aa)
GRHL1Grainyhead like transcription factor 1. (630 aa)
TGFB2Transforming growth factor beta 2. (442 aa)
CDH10Cadherin 10; Cadherins are calcium-dependent cell adhesion proteins. (789 aa)
PKP3Plakophilin 3. (803 aa)
OCEL1Occludin/ELL domain containing 1. (260 aa)
G1LUU5_AILMEUncharacterized protein. (621 aa)
CLDN10Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (231 aa)
FBF1Fas binding factor 1. (1160 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
G1LS85_AILMEMAGUK_N_PEST domain-containing protein. (118 aa)
PKP2Plakophilin 2. (882 aa)
CSKTyrosine-protein kinase. (450 aa)
DLG2Uncharacterized protein. (452 aa)
G1LPZ3_AILMEUncharacterized protein. (541 aa)
PKHD1Uncharacterized protein. (3386 aa)
CAMSAP3Calmodulin regulated spectrin associated protein family member 3. (1159 aa)
MPP7Membrane palmitoylated protein 7; Belongs to the MAGUK family. (576 aa)
NF2Neurofibromin 2. (596 aa)
CDH18Cadherin 18; Cadherins are calcium-dependent cell adhesion proteins. (793 aa)
EPHA4EPH receptor A4. (986 aa)
CDH24Cadherin 24; Cadherins are calcium-dependent cell adhesion proteins. (690 aa)
FLNAFilamin A. (2523 aa)
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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