(21 nodes) Response to pain network (Ailuropoda melanoleuca)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PIRT	Phosphoinositide interacting regulator of transient receptor potential channels. (137 aa)
	G1MGE1_AILME	G_PROTEIN_RECEP_F1_2 domain-containing protein. (88 aa)
	G1LGQ1_AILME	Uncharacterized protein. (201 aa)
	TRPA1	Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1120 aa)
	NMUR2	Neuromedin U receptor 2; Belongs to the G-protein coupled receptor 1 family. (400 aa)
	TRPV1	Transient receptor potential cation channel subfamily V member 1. (841 aa)
	MTOR	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2544 aa)
	P2RX2	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (371 aa)
	VWA1	Von Willebrand factor A domain containing 1. (309 aa)
	LPAR5	Lysophosphatidic acid receptor 5; Belongs to the G-protein coupled receptor 1 family. (373 aa)
	P2RX4	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (398 aa)
	P2RX3	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (405 aa)
	NTRK1	Tyrosine-protein kinase receptor. (725 aa)
	RELN	Reelin. (3030 aa)
	THBS4	Thrombospondin 4. (984 aa)
	TAC1	Tachykinin precursor 1. (129 aa)
	RET	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1121 aa)
	TACR1	G_PROTEIN_RECEP_F1_2 domain-containing protein. (212 aa)
	THBS1	Thrombospondin 1. (1182 aa)
	PRKCG	Protein kinase C gamma; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (697 aa)
	UCN	Urocortin. (123 aa)

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G1LGQ1_AILME	RELN	ENSAMEP00000006091	ENSAMEP00000015931	Uncharacterized protein.	Reelin.	0.890
G1MGE1_AILME	TAC1	ENSAMEP00000018423	ENSAMEP00000017243	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Tachykinin precursor 1.	0.990
G1MGE1_AILME	TRPV1	ENSAMEP00000018423	ENSAMEP00000009667	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Transient receptor potential cation channel subfamily V member 1.	0.463
MTOR	PRKCG	ENSAMEP00000010132	ENSAMEP00000004669	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	Protein kinase C gamma; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.915
P2RX2	P2RX3	ENSAMEP00000014329	ENSAMEP00000015203	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.709
P2RX2	P2RX4	ENSAMEP00000014329	ENSAMEP00000014965	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.576
P2RX3	P2RX2	ENSAMEP00000015203	ENSAMEP00000014329	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	0.709
P2RX3	P2RX4	ENSAMEP00000015203	ENSAMEP00000014965	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.955
P2RX3	TRPV1	ENSAMEP00000015203	ENSAMEP00000009667	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	Transient receptor potential cation channel subfamily V member 1.	0.441
P2RX4	P2RX2	ENSAMEP00000014965	ENSAMEP00000014329	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	0.576
P2RX4	P2RX3	ENSAMEP00000014965	ENSAMEP00000015203	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.955
PRKCG	MTOR	ENSAMEP00000004669	ENSAMEP00000010132	Protein kinase C gamma; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.915
RELN	G1LGQ1_AILME	ENSAMEP00000015931	ENSAMEP00000006091	Reelin.	Uncharacterized protein.	0.890
TAC1	G1MGE1_AILME	ENSAMEP00000017243	ENSAMEP00000018423	Tachykinin precursor 1.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.990
TAC1	TACR1	ENSAMEP00000017243	ENSAMEP00000018030	Tachykinin precursor 1.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.992
TAC1	TRPA1	ENSAMEP00000017243	ENSAMEP00000006318	Tachykinin precursor 1.	Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family.	0.532
TAC1	TRPV1	ENSAMEP00000017243	ENSAMEP00000009667	Tachykinin precursor 1.	Transient receptor potential cation channel subfamily V member 1.	0.725
TACR1	TAC1	ENSAMEP00000018030	ENSAMEP00000017243	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Tachykinin precursor 1.	0.992
THBS1	THBS4	ENSAMEP00000018260	ENSAMEP00000016575	Thrombospondin 1.	Thrombospondin 4.	0.415
THBS4	THBS1	ENSAMEP00000016575	ENSAMEP00000018260	Thrombospondin 4.	Thrombospondin 1.	0.415