STRINGSTRING
BMPR2 BMPR2 ACP5 ACP5 PTK2B PTK2B FGF10 FGF10 NCDN NCDN IAPP IAPP LIPA LIPA TCIRG1 TCIRG1 CTSK CTSK CAV1 CAV1 BAK1 BAK1 LRP5 LRP5 ATG5 ATG5 CTHRC1 CTHRC1 TIE1 TIE1 CBS CBS ACVRL1 ACVRL1 EDNRA EDNRA EXT1 EXT1 HIF1A HIF1A EFNA2 EFNA2 JAG1 JAG1 IL23A IL23A NOX4 NOX4 P3H4 P3H4 CHD7 CHD7 HOXA3 HOXA3 SNX10 SNX10 WNT16 WNT16 EPAS1 EPAS1 FLNA FLNA LIF LIF G1LMV3_AILME G1LMV3_AILME CCDC154 CCDC154 HNF1A HNF1A BSX BSX MDM2 MDM2 TNFSF11 TNFSF11 RASSF2 RASSF2 RSPO3 RSPO3 RAB3D RAB3D TGFB1 TGFB1 EPHA2 EPHA2 AXL AXL ELF3 ELF3 SRC SRC PTH1R PTH1R TIMP1 TIMP1 MEF2C MEF2C VDR VDR TRAF6 TRAF6 LRRK1 LRRK1 LGR4 LGR4 THBS4 THBS4 SPP2 SPP2 SEMA3C SEMA3C TPP1 TPP1 DLL4 DLL4 MITF MITF NOL3 NOL3 LTBP3 LTBP3 CRB1 CRB1 NOTCH2 NOTCH2 PTN PTN TPH1 TPH1 TGFB3 TGFB3 F2R F2R GPR55 GPR55 IL7 IL7 PANDA_011714 PANDA_011714 CCR2 CCR2 GJA5 GJA5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1040 aa)
ACP5Tartrate-resistant acid phosphatase type 5. (335 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1011 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (215 aa)
NCDNNeurochondrin. (729 aa)
IAPPIslet amyloid polypeptide. (89 aa)
LIPALipase; Belongs to the AB hydrolase superfamily. Lipase family. (396 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (839 aa)
CTSKCathepsin K; Belongs to the peptidase C1 family. (337 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
BAK1BCL2 antagonist/killer 1. (216 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1586 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (278 aa)
CTHRC1Collagen triple helix repeat containing 1. (221 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1138 aa)
CBSCystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (566 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
EDNRAEndothelin receptor type A. (428 aa)
EXT1Uncharacterized protein; Belongs to the glycosyltransferase 47 family. (427 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (823 aa)
EFNA2Ephrin A2; Belongs to the ephrin family. (164 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
IL23AInterleukin 23 subunit alpha. (193 aa)
NOX4NADPH oxidase 4. (603 aa)
P3H4Prolyl 3-hydroxylase family member 4 (non-enzymatic). (277 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2995 aa)
HOXA3Homeobox A3. (436 aa)
SNX10Sorting nexin 10. (198 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa)
EPAS1Endothelial PAS domain protein 1. (865 aa)
FLNAFilamin A. (2523 aa)
LIFLIF interleukin 6 family cytokine. (202 aa)
G1LMV3_AILMEUncharacterized protein. (100 aa)
CCDC154Coiled-coil domain containing 154. (648 aa)
HNF1AHNF1 homeobox A. (631 aa)
BSXBrain specific homeobox. (232 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (493 aa)
TNFSF11Tumor necrosis factor ligand superfamily member. (314 aa)
RASSF2Ras association domain family member 2. (326 aa)
RSPO3R-spondin 3. (295 aa)
RAB3DRAB3D, member RAS oncogene family. (219 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (355 aa)
EPHA2EPH receptor A2. (971 aa)
AXLAXL receptor tyrosine kinase. (895 aa)
ELF3E74 like ETS transcription factor 3. (369 aa)
SRCTyrosine-protein kinase. (542 aa)
PTH1RParathyroid hormone 1 receptor; Belongs to the G-protein coupled receptor 2 family. (587 aa)
TIMP1TIMP metallopeptidase inhibitor 1. (207 aa)
MEF2CMyocyte enhancer factor 2C. (473 aa)
VDRVitamin D receptor. (445 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
LRRK1Leucine rich repeat kinase 1. (1982 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (906 aa)
THBS4Thrombospondin 4. (984 aa)
SPP2Secreted phosphoprotein 2. (204 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (497 aa)
TPP1Tripeptidyl peptidase 1. (570 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
MITFMelanocyte inducing transcription factor. (526 aa)
NOL3Nucleolar protein 3. (222 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1252 aa)
CRB1Crumbs cell polarity complex component 1. (1409 aa)
NOTCH2Notch receptor 2. (2447 aa)
PTNPleiotrophin. (168 aa)
TPH1Tryptophan hydroxylase 1. (452 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (417 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (397 aa)
GPR55G protein-coupled receptor 55; Belongs to the G-protein coupled receptor 1 family. (320 aa)
IL7Uncharacterized protein. (45 aa)
PANDA_011714Uncharacterized protein. (124 aa)
CCR2C-C motif chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (373 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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