(24 nodes) Regulation of membrane repolarization network (Ailuropoda melanoleuca)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

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Your Input:
	SCN4B	Sodium voltage-gated channel beta subunit 4. (231 aa)
	G1L466_AILME	PID domain-containing protein. (567 aa)
	KCNQ1	Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (652 aa)
	KCNH6	Potassium voltage-gated channel subfamily H member 6. (996 aa)
	ZMPSTE24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
	WDR1	WD repeat domain 1. (624 aa)
	FLNA	Filamin A. (2523 aa)
	RNF207	Ring finger protein 207. (631 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (154 aa)
	SNTA1	Syntrophin alpha 1. (437 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
	KCNH2	Potassium voltage-gated channel subfamily H member 2. (1092 aa)
	NEDD4L	E3 ubiquitin-protein ligase. (924 aa)
	AKAP6	A-kinase anchoring protein 6. (2313 aa)
	CACNA2D1	Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1088 aa)
	SCN5A	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2010 aa)
	KCNE4	Potassium voltage-gated channel subfamily E regulatory subunit 4. (170 aa)
	KCNE1	Uncharacterized protein. (129 aa)
	KCNE5	Potassium voltage-gated channel subfamily E regulatory subunit 5. (89 aa)
	KCNE2	Potassium voltage-gated channel subfamily E regulatory subunit 2. (123 aa)
	KCNJ2	Potassium voltage-gated channel subfamily J member 2. (427 aa)
	KCNA5	Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (603 aa)
	KCNE3	Potassium voltage-gated channel subfamily E regulatory subunit 3. (99 aa)
	GJA5	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CACNA2D1	KCNH2	ENSAMEP00000017620	ENSAMEP00000014784	Calcium voltage-gated channel auxiliary subunit alpha2delta 1.	Potassium voltage-gated channel subfamily H member 2.	0.454
CACNA2D1	KCNJ2	ENSAMEP00000017620	ENSAMEP00000020624	Calcium voltage-gated channel auxiliary subunit alpha2delta 1.	Potassium voltage-gated channel subfamily J member 2.	0.466
CACNA2D1	KCNQ1	ENSAMEP00000017620	ENSAMEP00000002184	Calcium voltage-gated channel auxiliary subunit alpha2delta 1.	Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family.	0.482
CACNA2D1	SCN5A	ENSAMEP00000017620	ENSAMEP00000018684	Calcium voltage-gated channel auxiliary subunit alpha2delta 1.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.636
CAV1	CAV3	ENSAMEP00000001406	ENSAMEP00000013002	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.954
CAV1	FLNA	ENSAMEP00000001406	ENSAMEP00000007722	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Filamin A.	0.613
CAV3	CAV1	ENSAMEP00000013002	ENSAMEP00000001406	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.954
CAV3	FLNA	ENSAMEP00000013002	ENSAMEP00000007722	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Filamin A.	0.412
CAV3	KCNE1	ENSAMEP00000013002	ENSAMEP00000019782	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Uncharacterized protein.	0.437
CAV3	KCNE2	ENSAMEP00000013002	ENSAMEP00000020521	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Potassium voltage-gated channel subfamily E regulatory subunit 2.	0.457
CAV3	KCNH2	ENSAMEP00000013002	ENSAMEP00000014784	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Potassium voltage-gated channel subfamily H member 2.	0.473
CAV3	KCNJ2	ENSAMEP00000013002	ENSAMEP00000020624	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Potassium voltage-gated channel subfamily J member 2.	0.476
CAV3	SCN4B	ENSAMEP00000013002	ENSAMEP00000013956	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Sodium voltage-gated channel beta subunit 4.	0.436
CAV3	SCN5A	ENSAMEP00000013002	ENSAMEP00000018684	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.401
CAV3	SNTA1	ENSAMEP00000013002	ENSAMEP00000013699	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Syntrophin alpha 1.	0.489
FLNA	CAV1	ENSAMEP00000007722	ENSAMEP00000001406	Filamin A.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.613
FLNA	CAV3	ENSAMEP00000007722	ENSAMEP00000013002	Filamin A.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.412
FLNA	WDR1	ENSAMEP00000007722	ENSAMEP00000006010	Filamin A.	WD repeat domain 1.	0.562
G1L466_AILME	KCNE1	ENSAMEP00000001676	ENSAMEP00000019782	PID domain-containing protein.	Uncharacterized protein.	0.416
G1L466_AILME	SNTA1	ENSAMEP00000001676	ENSAMEP00000013699	PID domain-containing protein.	Syntrophin alpha 1.	0.493