STRINGSTRING
G1M5L9_AILME G1M5L9_AILME G1L675_AILME G1L675_AILME G1L644_AILME G1L644_AILME GSR GSR PTGS1 PTGS1 RDH11 RDH11 SESN1 SESN1 GPX3 GPX3 G1LP04_AILME G1LP04_AILME G1LPB6_AILME G1LPB6_AILME SELENOT SELENOT LTC4S LTC4S ALOX5AP ALOX5AP CLIC2 CLIC2 APOM APOM GPX7 GPX7 GPX8 GPX8 UBIAD1 UBIAD1 PRDX3 PRDX3 MARC2 MARC2 IPCEF1 IPCEF1 GLRX GLRX CCS CCS MGST2 MGST2 SESN2 SESN2 OPRD1 OPRD1 CERS1 CERS1 FANCC FANCC TXNRD2 TXNRD2 MPO MPO LPO LPO G1LZL4_AILME G1LZL4_AILME EPX EPX PRXL2C PRXL2C S100A8 S100A8 S100A9 S100A9 PRDX2 PRDX2 GPX1 GPX1 APOE APOE PRDX4 PRDX4 PRXL2A PRXL2A PRXL2B PRXL2B ESD ESD PRDX1 PRDX1 MFSD11 MFSD11 AKR1A1 AKR1A1 GPX5 GPX5 GPX6 GPX6 SRXN1 SRXN1 TPO TPO TXNL1 TXNL1 PXDN PXDN G1M8S1_AILME G1M8S1_AILME SOD1 SOD1 PXDNL PXDNL SELENOW SELENOW PIM1 PIM1 SOD2 SOD2 UPK3BL2 UPK3BL2 PTGS2 PTGS2 PRDX6 PRDX6 PRKN PRKN PANDA_009467 PANDA_009467 G1MBM7_AILME G1MBM7_AILME PTGES PTGES SELENOF SELENOF MT3 MT3 G1MFN0_AILME G1MFN0_AILME PRDX5 PRDX5 GSTO1 GSTO1 GSTO2 GSTO2 LOC100471725 LOC100471725 G1MPH1_AILME G1MPH1_AILME CAT CAT RDH12 RDH12 LOC100472986 LOC100472986 SELENOS SELENOS TXNDC17 TXNDC17 HBZ HBZ TXNRD1 TXNRD1 NQO1 NQO1 MGST3 MGST3 GSTK1 GSTK1 TXNRD3 TXNRD3 TP53INP1 TP53INP1 GSTM3 GSTM3 NXN NXN PARK7 PARK7 G1LA54_AILME G1LA54_AILME MGST1 MGST1 GPX2 GPX2 PINK1 PINK1 ABCB6 ABCB6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
G1M5L9_AILMEUncharacterized protein. (69 aa)
G1L675_AILMEHaptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. (346 aa)
G1L644_AILMEDSBA domain-containing protein. (176 aa)
GSRGlutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (428 aa)
PTGS1Prostaglandin-endoperoxide synthase 1. (618 aa)
RDH11Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa)
SESN1Sestrin 1. (551 aa)
GPX3Glutathione peroxidase; Belongs to the glutathione peroxidase family. (222 aa)
G1LP04_AILMEUncharacterized protein. (169 aa)
G1LPB6_AILMESod_Cu domain-containing protein. (133 aa)
SELENOTSelenoprotein T; Belongs to the SelWTH family. Selenoprotein T subfamily. (195 aa)
LTC4SLeukotriene C4 synthase. (130 aa)
ALOX5APArachidonate 5-lipoxygenase activating protein. (161 aa)
CLIC2Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (246 aa)
APOMApolipoprotein M. (188 aa)
GPX7Glutathione peroxidase; Belongs to the glutathione peroxidase family. (187 aa)
GPX8Glutathione peroxidase; Belongs to the glutathione peroxidase family. (209 aa)
UBIAD1UbiA prenyltransferase domain-containing protein 1; Prenyltransferase that mediates the formation of menaquinone- 4 (MK-4) and coenzyme Q10. MK-4 is a vitamin K2 isoform required for endothelial cell development. Mediates the conversion of phylloquinone (PK) into MK-4, probably by cleaving the side chain of phylloquinone (PK) to release 2-methyl-1,4-naphthoquinone (menadione; K3) and then prenylating it with geranylgeranyl pyrophosphate (GGPP) to form MK-4. Also plays a role in cardiovascular development independently of MK-4 biosynthesis, by acting as a coenzyme Q10 biosynthetic enzym [...] (337 aa)
PRDX3Thioredoxin domain-containing protein. (257 aa)
MARC2Mitochondrial amidoxime reducing component 2. (336 aa)
IPCEF1Interaction protein for cytohesin exchange factors 1. (437 aa)
GLRXGlutaredoxin. (106 aa)
CCSCopper chaperone for superoxide dismutase. (274 aa)
MGST2Microsomal glutathione S-transferase 2. (144 aa)
SESN2Sestrin 2. (481 aa)
OPRD1Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (358 aa)
CERS1TLC domain-containing protein. (267 aa)
FANCCFA complementation group C. (557 aa)
TXNRD2Thioredoxin reductase 2. (511 aa)
MPOMyeloperoxidase. (745 aa)
LPOLactoperoxidase. (712 aa)
G1LZL4_AILMEThioredoxin domain-containing protein. (211 aa)
EPXEosinophil peroxidase. (740 aa)
PRXL2CPeroxiredoxin like 2C. (186 aa)
S100A8Protein S100; Belongs to the S-100 family. (89 aa)
S100A9Protein S100; Belongs to the S-100 family. (130 aa)
PRDX2Thioredoxin domain-containing protein. (199 aa)
GPX1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (145 aa)
APOEApolipoprotein E. (311 aa)
PRDX4Peroxiredoxin 4. (272 aa)
PRXL2APeroxiredoxin like 2A. (229 aa)
PRXL2BPeroxiredoxin like 2B. (210 aa)
ESDS-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (282 aa)
PRDX1Peroxiredoxin 1. (199 aa)
MFSD11Major facilitator superfamily domain containing 11. (454 aa)
AKR1A1Aldo-keto reductase family 1 member A1. (326 aa)
GPX5Glutathione peroxidase; Belongs to the glutathione peroxidase family. (221 aa)
GPX6Glutathione peroxidase; Belongs to the glutathione peroxidase family. (136 aa)
SRXN1Sulfiredoxin. (95 aa)
TPOThyroid peroxidase. (936 aa)
TXNL1Thioredoxin like 1. (289 aa)
PXDNPeroxidasin. (1412 aa)
G1M8S1_AILMEFAD-binding FR-type domain-containing protein. (554 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
PXDNLPeroxidasin like. (1349 aa)
SELENOWSelenoprotein W. (87 aa)
PIM1Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (392 aa)
SOD2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (230 aa)
UPK3BL2Uncharacterized protein. (257 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
PRDX6Peroxiredoxin 6. (227 aa)
PRKNUbiquitin-like domain-containing protein. (287 aa)
PANDA_009467zf-RING_14 domain-containing protein. (74 aa)
G1MBM7_AILMERBR-type E3 ubiquitin transferase. (105 aa)
PTGESProstaglandin E synthase. (153 aa)
SELENOFSelenoprotein F. (161 aa)
MT3Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (68 aa)
G1MFN0_AILMEUncharacterized protein. (359 aa)
PRDX5Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (219 aa)
GSTO1Glutathione S-transferase omega 1. (241 aa)
GSTO2Glutathione S-transferase omega 2; Belongs to the GST superfamily. (244 aa)
LOC100471725Protein S100; Belongs to the S-100 family. (87 aa)
G1MPH1_AILMEThioredoxin domain-containing protein. (155 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (528 aa)
RDH12Retinol dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (320 aa)
LOC100472986Hemoglobin subunit zeta. (102 aa)
SELENOSSelenoprotein S. (188 aa)
TXNDC17Thioredoxin domain containing 17. (123 aa)
HBZGLOBIN domain-containing protein; Belongs to the globin family. (142 aa)
TXNRD1Thioredoxin reductase 1. (630 aa)
NQO1NAD(P)H quinone dehydrogenase 1. (273 aa)
MGST3Microsomal glutathione S-transferase 3. (155 aa)
GSTK1Glutathione S-transferase kappa. (226 aa)
TXNRD3Thioredoxin reductase 3. (564 aa)
TP53INP1Tumor protein p53 inducible nuclear protein 1. (239 aa)
GSTM3Glutathione S-transferase. (231 aa)
NXNThioredoxin domain-containing protein. (165 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
G1LA54_AILMEEF-hand domain-containing protein. (407 aa)
MGST1Microsomal glutathione S-transferase 1. (155 aa)
GPX2Glutathione peroxidase; Belongs to the glutathione peroxidase family. (141 aa)
PINK1PTEN induced kinase 1. (453 aa)
ABCB6ATP binding cassette subfamily B member 6 (Langereis blood group). (843 aa)
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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