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| | RAD52 | RAD52 homolog, DNA repair protein. (423 aa) |
| | CHEK1 | Checkpoint kinase 1. (439 aa) |
| | HELB | DNA helicase B. (1058 aa) |
| | MMS19 | MMS19 homolog, cytosolic iron-sulfur assembly component. (1046 aa) |
| | PBK | PDZ binding kinase. (323 aa) |
| | CLU | Clusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. (447 aa) |
| | G1L053_AILME | DUF4502 domain-containing protein. (170 aa) |
| | PANDA_016575 | DUF4502 domain-containing protein. (186 aa) |
| | SPIDR | DUF4503 domain-containing protein. (356 aa) |
| | PRKDC | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2279 aa) |
| | MAP3K20 | Uncharacterized protein. (800 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (215 aa) |
| | POGZ | Pogo transposable element derived with ZNF domain. (1374 aa) |
| | RAD9A | Cell cycle checkpoint control protein; Belongs to the rad9 family. (394 aa) |
| | ZNF385A | Zinc finger protein 385A. (342 aa) |
| | PLA2R1 | Phospholipase A2 receptor 1. (1462 aa) |
| | VPS72 | YL1_C domain-containing protein. (364 aa) |
| | MCRS1 | Microspherule protein 1. (475 aa) |
| | MEAF6 | MYST/Esa1 associated factor 6. (172 aa) |
| | MYCN | MYCN proto-oncogene, bHLH transcription factor. (464 aa) |
| | WDR48 | WD repeat domain 48. (677 aa) |
| | PAXIP1 | PAX interacting protein 1. (1249 aa) |
| | FBXO5 | F-box protein 5. (383 aa) |
| | KMT5B | Lysine methyltransferase 5B. (880 aa) |
| | RFWD3 | E3 ubiquitin-protein ligase RFWD3; E3 ubiquitin-protein ligase required for the repair of DNA interstrand cross-links (ICL) in response to DNA damage. Plays a key role in RPA-mediated DNA damage signaling and repair. Acts by mediating ubiquitination of the RPA complex (RPA1, RPA2 and RPA3 subunits) and RAD51 at stalled replication forks, leading to remove them from DNA damage sites and promote homologous recombination. Also mediates the ubiquitination of p53/TP53 in the late response to DNA damage, and acts as a positive regulator of p53/TP53 stability, thereby regulating the G1/S DNA [...] (790 aa) |
| | SPIRE2 | Spire type actin nucleation factor 2. (637 aa) |
| | G1L496_AILME | Uncharacterized protein. (1131 aa) |
| | TEX15 | Testis expressed 15, meiosis and synapsis associated. (2849 aa) |
| | UBE2V2 | Ubiquitin conjugating enzyme E2 V2. (147 aa) |
| | ZNHIT1 | Zinc finger HIT-type containing 1. (155 aa) |
| | NUDT16L1 | Nudix hydrolase 16 like 1. (210 aa) |
| | HDGFL2 | HDGF like 2. (643 aa) |
| | PTTG1IP | PTTG1 interacting protein. (155 aa) |
| | FBH1 | F-box DNA helicase 1. (1048 aa) |
| | SIRT6 | Sirtuin 6. (361 aa) |
| | DHX9 | DExH-box helicase 9. (1276 aa) |
| | PIAS4 | Protein inhibitor of activated STAT 4. (518 aa) |
| | COPS3 | COP9 signalosome subunit 3. (423 aa) |
| | HDAC10 | Histone deacetylase 10. (669 aa) |
| | ACTR8 | Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize (By similarity); Belongs to the actin family. ARP8 subfamily. (624 aa) |
| | NFRKB | Nuclear factor related to kappaB binding protein. (1298 aa) |
| | RADX | RPA1 related single stranded DNA binding protein, X-linked. (859 aa) |
| | NSMCE1 | NSE1 homolog, SMC5-SMC6 complex component. (268 aa) |
| | TIMELESS | Timeless circadian regulator. (1207 aa) |
| | G1LAZ0_AILME | MRG domain-containing protein. (263 aa) |
| | RNF168 | Ring finger protein 168. (569 aa) |
| | KMT5C | Lysine methyltransferase 5C. (461 aa) |
| | ZNF365 | Zinc finger protein 365. (407 aa) |
| | WRNIP1 | WRN helicase interacting protein 1. (601 aa) |
| | NACC2 | NACC family member 2. (506 aa) |
| | INO80D | INO80 complex subunit D. (1030 aa) |
| | CCAR2 | Cell cycle and apoptosis regulator 2. (918 aa) |
| | G1L831_AILME | CULLIN_2 domain-containing protein; Belongs to the cullin family. (405 aa) |
| | PSMD10 | Proteasome 26S subunit, non-ATPase 10. (231 aa) |
| | TTI2 | TELO2 interacting protein 2. (508 aa) |
| | CRY1 | Cryptochrome circadian regulator 1. (587 aa) |
| | DDX5 | DEAD-box helicase 5; Belongs to the DEAD box helicase family. (671 aa) |
| | PNKP | Polynucleotide kinase 3'-phosphatase. (521 aa) |
| | EP400 | Uncharacterized protein. (1872 aa) |
| | RBBP8 | RB binding protein 8, endonuclease. (903 aa) |
| | BCL2L12 | BCL2 like 12. (255 aa) |
| | G1M5N4_AILME | Uncharacterized protein. (282 aa) |
| | DMAP1 | DNA methyltransferase 1 associated protein 1. (468 aa) |
| | FEM1B | Fem-1 homolog B. (629 aa) |
| | ING4 | Inhibitor of growth protein. (248 aa) |
| | UBQLN4 | Ubiquilin 4. (573 aa) |
| | NSD2 | Nuclear receptor binding SET domain protein 2. (1370 aa) |
| | PARP9 | Poly(ADP-ribose) polymerase family member 9. (861 aa) |
| | DTX3L | Deltex E3 ubiquitin ligase 3L. (733 aa) |
| | PARP1 | Poly [ADP-ribose] polymerase. (981 aa) |
| | RUVBL2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (467 aa) |
| | BCL7A | BAF chromatin remodeling complex subunit BCL7A. (204 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (452 aa) |
| | G1M863_AILME | Uncharacterized protein. (85 aa) |
| | USP1 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (786 aa) |
| | UBR5 | Ubiquitin protein ligase E3 component n-recognin 5. (2795 aa) |
| | POLQ | DNA polymerase theta. (2630 aa) |
| | KDM1A | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (818 aa) |
| | FMR1 | Fragile X mental retardation 1. (632 aa) |
| | CDK9 | Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (370 aa) |
| | ZCWPW1 | Zinc finger CW-type and PWWP domain containing 1. (633 aa) |
| | POT1 | Protection of telomeres 1. (635 aa) |
| | INO80E | INO80 complex subunit E. (248 aa) |
| | RUVBL1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa) |
| | PPP4R2 | Protein phosphatase 4 regulatory subunit 2. (404 aa) |
| | KMT5A | Lysine methyltransferase 5A. (308 aa) |
| | ELL3 | Elongation factor for RNA polymerase II 3. (398 aa) |
| | PPP4C | Serine/threonine-protein phosphatase. (307 aa) |
| | TP53BP1 | Tumor protein p53 binding protein 1. (1978 aa) |
| | RNF8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (483 aa) |
| | RAD51AP1 | RAD51 associated protein 1. (356 aa) |
| | TIGAR | TP53 induced glycolysis regulatory phosphatase. (269 aa) |
| | ETAA1 | ETAA1 activator of ATR kinase. (904 aa) |
| | ENDOG | Endonuclease G. (219 aa) |
| | SMYD2 | Uncharacterized protein. (381 aa) |
| | G1MBH0_AILME | Uncharacterized protein. (108 aa) |
| | OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2. (234 aa) |
| | FBXO4 | F-box protein 4. (387 aa) |
| | UCHL5 | Ubiquitin carboxyl-terminal hydrolase. (329 aa) |
| | EYA4 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (645 aa) |
| | ABL1 | Tyrosine-protein kinase. (1150 aa) |
| | OGG1 | 8-oxoguanine DNA glycosylase. (344 aa) |
| | BRD8 | Bromo domain-containing protein. (951 aa) |
| | TRIP12 | Thyroid hormone receptor interactor 12. (2040 aa) |
| | G1MDY4_AILME | Uncharacterized protein. (258 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3058 aa) |
| | ANKRD1 | Ankyrin repeat domain 1. (319 aa) |
| | FXR2 | FMR1 autosomal homolog 2. (660 aa) |
| | INO80 | INO80 complex ATPase subunit. (1561 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa) |
| | MAGEF1 | MAGE family member F1. (310 aa) |
| | WRAP53 | WD repeat containing antisense to TP53. (537 aa) |
| | RAD51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (264 aa) |
| | G1MF02_AILME | Uncharacterized protein. (75 aa) |
| | RPS3 | KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (248 aa) |
| | RNF169 | Ring finger protein 169. (547 aa) |
| | FAM168A | Family with sequence similarity 168 member A. (244 aa) |
| | EEF1E1 | GST C-terminal domain-containing protein. (176 aa) |
| | MRGBP | MRG domain binding protein. (155 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa) |
| | SIRT7 | Sirtuin 7. (336 aa) |
| | DYRK3 | Dual specificity tyrosine phosphorylation regulated kinase 3. (584 aa) |
| | SLF2 | SMC5-SMC6 complex localization factor 2. (1160 aa) |
| | OTUB1 | Ubiquitin thioesterase. (301 aa) |
| | SIRT1 | Sirtuin 1. (607 aa) |
| | DYRK1A | Dual specificity tyrosine phosphorylation regulated kinase 1A. (763 aa) |
| | SFRP2 | Secreted frizzled related protein 2. (301 aa) |
| | MORF4L2 | MRG domain-containing protein. (288 aa) |
| | CEBPG | CCAAT enhancer binding protein gamma. (147 aa) |
| | G1MLU7_AILME | Uncharacterized protein. (169 aa) |
| | FIGNL1 | Fidgetin like 1; Belongs to the AAA ATPase family. (676 aa) |
| | TRIM32 | Tripartite motif containing 32. (655 aa) |
| | ACKR3 | Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (362 aa) |
| | MFSD11 | Major facilitator superfamily domain containing 11. (454 aa) |
| | SNAI1 | Snail family transcriptional repressor 1. (264 aa) |
| | ARID2 | AT-rich interaction domain 2. (1836 aa) |
| | EYA2 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (440 aa) |
| | DDX39A | DExD-box helicase 39A. (435 aa) |
| | IER3 | Immediate early response 3. (156 aa) |
| | TPT1 | Tumor protein, translationally-controlled 1; Belongs to the TCTP family. (179 aa) |
| | SPIRE1 | Spire type actin nucleation factor 1. (499 aa) |
| | SETD2 | SET domain containing 2, histone lysine methyltransferase. (2540 aa) |
| | KLHL15 | Kelch like family member 15. (604 aa) |
| | WAS | WASP actin nucleation promoting factor. (469 aa) |
| | ATR | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2644 aa) |
| | ERCC1 | ERCC excision repair 1, endonuclease non-catalytic subunit. (298 aa) |
| | KAT7 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (611 aa) |
| | FXR1 | FMR1 autosomal homolog 1. (663 aa) |
| | CYREN | Cell cycle regulator of NHEJ. (158 aa) |
| | BRCC3 | BRCA1/BRCA2-containing complex subunit 3. (291 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (451 aa) |
| | AXIN2 | Axin 2. (841 aa) |
| | YEATS4 | YEATS domain containing 4. (227 aa) |
| | TMEM161A | Transmembrane protein 161A. (481 aa) |
| | G1LYU2_AILME | Uncharacterized protein. (199 aa) |
| | G1LYB1_AILME | TCTP domain-containing protein; Belongs to the TCTP family. (165 aa) |
| | CDKN2D | Cyclin dependent kinase inhibitor 2D. (166 aa) |
| | ERCC4 | ERCC excision repair 4, endonuclease catalytic subunit. (913 aa) |
| | G1LXT4_AILME | SEA domain-containing protein. (275 aa) |
| | EYA3 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (573 aa) |
| | SOX4 | SRY-box transcription factor 4. (264 aa) |
| | ARMT1 | Acidic residue methyltransferase 1. (441 aa) |
| | SMG1 | SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (3656 aa) |
| | NSMCE4A | Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (384 aa) |
| | EYA1 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (425 aa) |
| | ANKLE1 | Ankyrin repeat and LEM domain containing 1. (577 aa) |
| | BABAM1 | Uncharacterized protein. (364 aa) |
| | ERCC6 | ERCC excision repair 6, chromatin remodeling factor. (1481 aa) |
| | EPC1 | Enhancer of polycomb homolog. (842 aa) |
| | AUNIP | Aurora kinase A and ninein interacting protein. (355 aa) |
| | CUL4A | Cullin 4A; Belongs to the cullin family. (723 aa) |
| | SHLD1 | Shieldin complex subunit 1. (206 aa) |
| | SMCHD1 | Structural maintenance of chromosomes flexible hinge domain containing 1. (1988 aa) |
| | SHLD2 | Shieldin complex subunit 2. (803 aa) |
| | BCLAF1 | BCL2 associated transcription factor 1. (923 aa) |
| | G1LTN2_AILME | TCTP domain-containing protein; Belongs to the TCTP family. (173 aa) |
| | MAD2L2 | Mitotic arrest deficient 2 like 2. (211 aa) |
| | SNAI2 | Snail family transcriptional repressor 2. (268 aa) |
| | RECQL5 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (985 aa) |
| | DDX39B | DExD-box helicase 39B. (440 aa) |
| | PARP3 | Poly [ADP-ribose] polymerase. (531 aa) |
| | G1LRK2_AILME | TCTP domain-containing protein; Belongs to the TCTP family. (113 aa) |
| | PML | Promyelocytic leukemia. (880 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | HMGB1 | Uncharacterized protein. (215 aa) |
| | G1LQE5_AILME | HMG box domain-containing protein. (196 aa) |
| | MRNIP | MRN complex interacting protein. (337 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (493 aa) |
| | RIF1 | Replication timing regulatory factor 1. (2450 aa) |
| | CCDC117 | Coiled-coil domain containing 117. (217 aa) |
| | NEK4 | NIMA related kinase 4. (846 aa) |
| | DEK | DEK proto-oncogene. (377 aa) |
| | SPRED1 | Sprouty related EVH1 domain containing 1. (443 aa) |
| | THOC5 | THO complex 5. (683 aa) |
| | MBTD1 | Mbt domain containing 1. (651 aa) |
| | CD44 | CD44 molecule (Indian blood group). (762 aa) |
| | G1LMU8_AILME | Uncharacterized protein. (384 aa) |
| | SLF1 | SMC5-SMC6 complex localization factor 1. (1060 aa) |
| | KHDC3L | KH domain containing 3 like, subcortical maternal complex member. (225 aa) |
| | OOEP | Oocyte expressed protein. (149 aa) |
| | CGAS | Cyclic GMP-AMP synthase. (517 aa) |
| | HIC1 | HIC ZBTB transcriptional repressor 1. (640 aa) |
| | BCL7C | BAF chromatin remodeling complex subunit BCL7C. (214 aa) |
| | TRIM28 | Tripartite motif containing 28. (772 aa) |
| | PARG | Uncharacterized protein. (490 aa) |
| | UIMC1 | Ubiquitin interaction motif containing 1. (674 aa) |
| | G1LL71_AILME | Ribosomal_S3_C domain-containing protein. (234 aa) |
| | FUS | FUS RNA binding protein. (511 aa) |
| | THOC1 | THO complex 1. (659 aa) |
| | CLUL1 | Clusterin; Belongs to the clusterin family. (473 aa) |
| | G1LIZ7_AILME | Uncharacterized protein. (54 aa) |
| | PARPBP | PARP1 binding protein. (652 aa) |
| | FANCB | FA complementation group B. (867 aa) |
| | ING3 | Inhibitor of growth protein. (418 aa) |
| | USP47 | Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1379 aa) |
| | HSF1 | Heat shock transcription factor 1. (552 aa) |
| | ATAD5 | ATPase family AAA domain containing 5. (1851 aa) |
| | TERF2IP | TERF2 interacting protein. (392 aa) |
| | FAM178B | Family with sequence similarity 178 member B. (648 aa) |
| | DDIAS | DNA damage induced apoptosis suppressor. (952 aa) |
| | HELQ | Helicase, POLQ like. (1004 aa) |
| | ABRAXAS1 | Abraxas 1, BRCA1 A complex subunit. (409 aa) |
| | FOXM1 | Forkhead box M1. (767 aa) |
| | EPC2 | Enhancer of polycomb homolog. (807 aa) |
| | SKIL | SKI like proto-oncogene. (684 aa) |
| | CD74 | CD74 molecule. (295 aa) |
| | ZMPSTE24 | CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa) |
| | TFPT | TCF3 fusion partner. (253 aa) |
| | PRKCG | Protein kinase C gamma; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (697 aa) |
| | XRCC1 | X-ray repair cross complementing 1. (643 aa) |
| | ERCC8 | ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (396 aa) |
