STRINGSTRING
MFNG MFNG PGAP3 PGAP3 B4GALNT4 B4GALNT4 ST6GALNAC2 ST6GALNAC2 ST6GALNAC1 ST6GALNAC1 ST8SIA6 ST8SIA6 B3GNT3 B3GNT3 ST8SIA2 ST8SIA2 AP4M1 AP4M1 VPS41 VPS41 TRAPPC3L TRAPPC3L GALNT13 GALNT13 AP3M2 AP3M2 B4GALNT2 B4GALNT2 COPZ2 COPZ2 CSGALNACT1 CSGALNACT1 SORT1 SORT1 GALNT12 GALNT12 B4GALNT3 B4GALNT3 SYS1 SYS1 ST8SIA4 ST8SIA4 GOSR1 GOSR1 SEC16A SEC16A TRAPPC4 TRAPPC4 ST3GAL4 ST3GAL4 GALNT1 GALNT1 ST6GALNAC3 ST6GALNAC3 TRAPPC1 TRAPPC1 FUT10 FUT10 GALNT3 GALNT3 AP1G1 AP1G1 COPB1 COPB1 ATG9A ATG9A ST3GAL2 ST3GAL2 GALNT6 GALNT6 CAV2 CAV2 CAV1 CAV1 B3GNT10 B3GNT10 ST3GAL3 ST3GAL3 GALNT18 GALNT18 ST6GAL1 ST6GAL1 COPZ1 COPZ1 TRAPPC3 TRAPPC3 CSGALNACT2 CSGALNACT2 CHST8 CHST8 RFNG RFNG SAR1B SAR1B SAR1A SAR1A COQ6 COQ6 GALNT4 GALNT4 B3GALT1 B3GALT1 LOC100468460 LOC100468460 B3GNT6 B3GNT6 B3GALT6 B3GALT6 CHST14 CHST14 B3GALNT1 B3GALNT1 FUT9 FUT9 B3GALT5 B3GALT5 B3GNT4 B3GNT4 B3GNT9 B3GNT9 B3GALT4 B3GALT4 FUT1 FUT1 FUT2 FUT2 B3GNT5 B3GNT5 B3GNT8 B3GNT8 B3GALT2 B3GALT2 ST3GAL5 ST3GAL5 COPG2 COPG2 COPB2 COPB2 EBAG9 EBAG9 G1LIQ8_AILME G1LIQ8_AILME B3GAT3 B3GAT3 CHST11 CHST11 ST6GALNAC5 ST6GALNAC5 B3GAT1 B3GAT1 COG8 COG8 FUT4 FUT4 SULF1 SULF1 AP1M2 AP1M2 B3GAT2 B3GAT2 CAV3 CAV3 ST8SIA5 ST8SIA5 COG6 COG6 ARCN1 ARCN1 ST6GAL2 ST6GAL2 GALNT11 GALNT11 FUT7 FUT7 CHPF2 CHPF2 GALNT9 GALNT9 G1M5M2_AILME G1M5M2_AILME ATG9B ATG9B CHST9 CHST9 COPA COPA CHSY1 CHSY1 GALNT7 GALNT7 GALNT5 GALNT5 SEC16B SEC16B GALNT16 GALNT16 ST8SIA3 ST8SIA3 G1M8B5_AILME G1M8B5_AILME ST6GALNAC6 ST6GALNAC6 ST6GALNAC4 ST6GALNAC4 COPG1 COPG1 ST3GAL6 ST3GAL6 GALNT8 GALNT8 CHST10 CHST10 B3GALNT2 B3GALNT2 AP1G2 AP1G2 GALNT10 GALNT10 FUT11 FUT11 CHPF CHPF ST3GAL1 ST3GAL1 ST8SIA1 ST8SIA1 MPPE1 MPPE1 SORL1 SORL1 GALNT15 GALNT15 PSEN2 PSEN2 UBIAD1 UBIAD1 GBA2 GBA2 G1LTF2_AILME G1LTF2_AILME AP1M1 AP1M1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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MFNGBeta-1,3-N-acetylglucosaminyltransferase. (321 aa)
PGAP3Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family. (316 aa)
B4GALNT4Beta-1,4-N-acetylgalactosaminyltransferase; Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'- diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans. (1045 aa)
ST6GALNAC2ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2; Belongs to the glycosyltransferase 29 family. (376 aa)
ST6GALNAC1ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (548 aa)
ST8SIA6ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6; Belongs to the glycosyltransferase 29 family. (373 aa)
B3GNT3Hexosyltransferase. (377 aa)
ST8SIA2ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2; Belongs to the glycosyltransferase 29 family. (365 aa)
AP4M1AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] (459 aa)
VPS41Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (854 aa)
TRAPPC3LTrafficking protein particle complex subunit; May play a role in vesicular transport from endoplasmic reticulum to Golgi. (181 aa)
GALNT13Polypeptide N-acetylgalactosaminyltransferase. (561 aa)
AP3M2AP-3 complex subunit mu-2. (419 aa)
B4GALNT2Beta-1,4 N-acetylgalactosaminyltransferase. (512 aa)
COPZ2Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (206 aa)
CSGALNACT1Hexosyltransferase. (532 aa)
SORT1Sortilin. (814 aa)
GALNT12Polypeptide N-acetylgalactosaminyltransferase. (497 aa)
B4GALNT3Beta-1,4-N-acetylgalactosaminyltransferase; Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'- diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans. (945 aa)
SYS1Protein SYS1 homolog; Involved in protein trafficking. Belongs to the SYS1 family. (151 aa)
ST8SIA4ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4; Belongs to the glycosyltransferase 29 family. (359 aa)
GOSR1Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. (250 aa)
SEC16AProtein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (2362 aa)
TRAPPC4Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family. (219 aa)
ST3GAL4ST3 beta-galactoside alpha-2,3-sialyltransferase 4; Belongs to the glycosyltransferase 29 family. (333 aa)
GALNT1Polypeptide N-acetylgalactosaminyltransferase. (560 aa)
ST6GALNAC3ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3; Belongs to the glycosyltransferase 29 family. (301 aa)
TRAPPC1Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family. (145 aa)
FUT10Alpha-(1,3)-fucosyltransferase; Probable fucosyltransferase; Belongs to the glycosyltransferase 10 family. (522 aa)
GALNT3Polypeptide N-acetylgalactosaminyltransferase. (632 aa)
AP1G1AP-1 complex subunit gamma. (844 aa)
COPB1Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (957 aa)
ATG9AAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (842 aa)
ST3GAL2ST3 beta-galactoside alpha-2,3-sialyltransferase 2; Belongs to the glycosyltransferase 29 family. (371 aa)
GALNT6Polypeptide N-acetylgalactosaminyltransferase. (634 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
B3GNT10Hexosyltransferase. (271 aa)
ST3GAL3ST3 beta-galactoside alpha-2,3-sialyltransferase 3; Belongs to the glycosyltransferase 29 family. (306 aa)
GALNT18Polypeptide N-acetylgalactosaminyltransferase. (607 aa)
ST6GAL1ST6 beta-galactoside alpha-2,6-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (399 aa)
COPZ1Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (187 aa)
TRAPPC3Trafficking protein particle complex subunit; May play a role in vesicular transport from endoplasmic reticulum to Golgi. (180 aa)
CSGALNACT2Hexosyltransferase. (544 aa)
CHST8Carbohydrate sulfotransferase. (373 aa)
RFNGBeta-1,3-N-acetylglucosaminyltransferase. (339 aa)
SAR1BSecretion associated Ras related GTPase 1B; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
SAR1ASecretion associated Ras related GTPase 1A; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
COQ6Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (475 aa)
GALNT4Polypeptide N-acetylgalactosaminyltransferase. (578 aa)
B3GALT1Hexosyltransferase. (326 aa)
LOC100468460Glyco_tran_10_N domain-containing protein. (383 aa)
B3GNT6Hexosyltransferase. (381 aa)
B3GALT6Hexosyltransferase. (187 aa)
CHST14Carbohydrate sulfotransferase. (343 aa)
B3GALNT1Hexosyltransferase. (331 aa)
FUT9Fucosyltransferase 9. (361 aa)
B3GALT5Hexosyltransferase. (311 aa)
B3GNT4Hexosyltransferase. (379 aa)
B3GNT9Hexosyltransferase. (402 aa)
B3GALT4Hexosyltransferase. (384 aa)
FUT1L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (361 aa)
FUT2L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (340 aa)
B3GNT5Hexosyltransferase. (379 aa)
B3GNT8Hexosyltransferase. (397 aa)
B3GALT2Hexosyltransferase. (422 aa)
ST3GAL5ST3 beta-galactoside alpha-2,3-sialyltransferase 5; Belongs to the glycosyltransferase 29 family. (391 aa)
COPG2Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (874 aa)
COPB2Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (905 aa)
EBAG9Receptor-binding cancer antigen expressed on SiSo cells; May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases. (213 aa)
G1LIQ8_AILMECarbohydrate sulfotransferase. (105 aa)
B3GAT3Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (330 aa)
CHST11Carbohydrate sulfotransferase. (352 aa)
ST6GALNAC5ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5; Belongs to the glycosyltransferase 29 family. (249 aa)
B3GAT1Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (347 aa)
COG8Conserved oligomeric Golgi complex subunit 8; Belongs to the COG8 family. (608 aa)
FUT4Fucosyltransferase 4. (358 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (868 aa)
AP1M2AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (467 aa)
B3GAT2Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (292 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (154 aa)
ST8SIA5ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5; Belongs to the glycosyltransferase 29 family. (412 aa)
COG6Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function. (653 aa)
ARCN1Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (511 aa)
ST6GAL2ST6 beta-galactoside alpha-2,6-sialyltransferase 2; Belongs to the glycosyltransferase 29 family. (525 aa)
GALNT11Polypeptide N-acetylgalactosaminyltransferase. (608 aa)
FUT7Fucosyltransferase 7. (390 aa)
CHPF2Hexosyltransferase. (784 aa)
GALNT9Polypeptide N-acetylgalactosaminyltransferase. (605 aa)
G1M5M2_AILMEAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (336 aa)
ATG9BAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (363 aa)
CHST9Carbohydrate sulfotransferase. (404 aa)
COPACoatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1233 aa)
CHSY1Hexosyltransferase. (770 aa)
GALNT7Polypeptide N-acetylgalactosaminyltransferase. (657 aa)
GALNT5Polypeptide N-acetylgalactosaminyltransferase. (940 aa)
SEC16BProtein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (1062 aa)
GALNT16Polypeptide N-acetylgalactosaminyltransferase. (553 aa)
ST8SIA3ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3; Belongs to the glycosyltransferase 29 family. (455 aa)
G1M8B5_AILMEL-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (391 aa)
ST6GALNAC6ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6; Belongs to the glycosyltransferase 29 family. (366 aa)
ST6GALNAC4ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4; Belongs to the glycosyltransferase 29 family. (306 aa)
COPG1Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (874 aa)
ST3GAL6ST3 beta-galactoside alpha-2,3-sialyltransferase 6; Belongs to the glycosyltransferase 29 family. (334 aa)
GALNT8Polypeptide N-acetylgalactosaminyltransferase. (635 aa)
CHST10Carbohydrate sulfotransferase. (374 aa)
B3GALNT2Hexosyltransferase. (502 aa)
AP1G2AP-1 complex subunit gamma. (815 aa)
GALNT10Polypeptide N-acetylgalactosaminyltransferase. (589 aa)
FUT11Alpha-(1,3)-fucosyltransferase; Probable fucosyltransferase; Belongs to the glycosyltransferase 10 family. (493 aa)
CHPFHexosyltransferase. (775 aa)
ST3GAL1ST3 beta-galactoside alpha-2,3-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (342 aa)
ST8SIA1ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (356 aa)
MPPE1Metallophosphoesterase 1; Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI- anchor proteins (By similarity); Belongs to the metallophosphoesterase superfamily. MPPE1 family. (393 aa)
SORL1Sortilin related receptor 1. (2178 aa)
GALNT15Polypeptide N-acetylgalactosaminyltransferase. (634 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (480 aa)
UBIAD1UbiA prenyltransferase domain-containing protein 1; Prenyltransferase that mediates the formation of menaquinone- 4 (MK-4) and coenzyme Q10. MK-4 is a vitamin K2 isoform required for endothelial cell development. Mediates the conversion of phylloquinone (PK) into MK-4, probably by cleaving the side chain of phylloquinone (PK) to release 2-methyl-1,4-naphthoquinone (menadione; K3) and then prenylating it with geranylgeranyl pyrophosphate (GGPP) to form MK-4. Also plays a role in cardiovascular development independently of MK-4 biosynthesis, by acting as a coenzyme Q10 biosynthetic enzym [...] (337 aa)
GBA2Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. (933 aa)
G1LTF2_AILMEUncharacterized protein; Belongs to the glycosyltransferase 29 family. (252 aa)
AP1M1AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (435 aa)
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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