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ARHGEF11 ARHGEF11 PAK1 PAK1 DSTN DSTN PLXND1 PLXND1 SEMA5A SEMA5A PAK2 PAK2 RHOC RHOC SEMA4D SEMA4D G1L9J3_AILME G1L9J3_AILME DPYSL3 DPYSL3 CDK5R2 CDK5R2 PLXNB2 PLXNB2 DPYSL5 DPYSL5 SEMA6D SEMA6D SEMA6B SEMA6B SRMS SRMS PTK6 PTK6 MET MET PLXNB1 PLXNB1 SEMA6C SEMA6C TYROBP TYROBP SEMA3A SEMA3A G1L153_AILME G1L153_AILME PLXNA3 PLXNA3 DPYSL2 DPYSL2 G1M255_AILME G1M255_AILME RHOA RHOA TLN2 TLN2 PAK3 PAK3 SEMA3B SEMA3B HSP90AB1 HSP90AB1 ROCK2 ROCK2 CRMP1 CRMP1 DPYSL4 DPYSL4 PTPRC PTPRC PKHD1L1 PKHD1L1 SEMA4B SEMA4B CDK5 CDK5 FES FES RRAS RRAS SEMA4A SEMA4A PLXNA4 PLXNA4 LIMK1 LIMK1 CFL2 CFL2 G1LVS4_AILME G1LVS4_AILME ERBB2 ERBB2 PLXNC1 PLXNC1 TLN1 TLN1 CD72 CD72 SEMA7A SEMA7A SEMA3G SEMA3G G1LPZ3_AILME G1LPZ3_AILME CFL1 CFL1 NRP1 NRP1 DPYS DPYS PLXNB3 PLXNB3 CDK5R1 CDK5R1 RHOB RHOB PKHD1 PKHD1 ARHGAP35 ARHGAP35 PLXNA2 PLXNA2 ARHGEF12 ARHGEF12 ENSAMEP00000008181 ENSAMEP00000008181 LIMK2 LIMK2 RND1 RND1 GSK3B GSK3B ROCK1 ROCK1 PLXNA1 PLXNA1 TLNRD1 TLNRD1 HSP90AA1 HSP90AA1 SEMA3E SEMA3E FYN FYN FARP2 FARP2 SEMA6A SEMA6A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ARHGEF11Uncharacterized protein. (889 aa)
PAK1Non-specific serine/threonine protein kinase. (551 aa)
DSTNADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (165 aa)
PLXND1Plexin D1. (1758 aa)
SEMA5ASemaphorin 5A. (1073 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
RHOCRas homolog family member C. (193 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (873 aa)
G1L9J3_AILMEUncharacterized protein. (121 aa)
DPYSL3Dihydropyrimidinase like 3. (571 aa)
CDK5R2Cyclin-dependent kinase 5 activator. (304 aa)
PLXNB2Plexin B2. (2029 aa)
DPYSL5Dihydropyrimidinase like 5. (568 aa)
SEMA6DSemaphorin 6D; Belongs to the semaphorin family. (1073 aa)
SEMA6BSemaphorin 6B; Belongs to the semaphorin family. (684 aa)
SRMSTyrosine-protein kinase. (494 aa)
PTK6Tyrosine-protein kinase. (442 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1400 aa)
PLXNB1Plexin B1. (2135 aa)
SEMA6CSemaphorin 6C; Belongs to the semaphorin family. (879 aa)
TYROBPTYRO protein tyrosine kinase binding protein. (114 aa)
SEMA3ASemaphorin 3A. (772 aa)
G1L153_AILMEHATPase_c domain-containing protein. (573 aa)
PLXNA3Plexin A3. (1881 aa)
DPYSL2Dihydropyrimidinase like 2. (675 aa)
G1M255_AILMEUncharacterized protein. (373 aa)
RHOARas homolog family member A. (193 aa)
TLN2Talin 2. (2542 aa)
PAK3P21 (RAC1) activated kinase 3. (580 aa)
SEMA3BSemaphorin 3B; Belongs to the semaphorin family. (741 aa)
HSP90AB1Heat shock protein 90 alpha family class B member 1. (741 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1407 aa)
CRMP1Collapsin response mediator protein 1. (635 aa)
DPYSL4Dihydropyrimidinase like 4. (687 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1260 aa)
PKHD1L1PKHD1 like 1. (4175 aa)
SEMA4BSemaphorin 4B; Belongs to the semaphorin family. (833 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (819 aa)
RRASRAS related. (180 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (758 aa)
PLXNA4Uncharacterized protein. (203 aa)
LIMK1LIM domain kinase 1. (632 aa)
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
G1LVS4_AILMEADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (162 aa)
ERBB2Receptor protein-tyrosine kinase. (1263 aa)
PLXNC1Plexin C1. (1561 aa)
TLN1Talin 1. (2553 aa)
CD72CD72 molecule. (356 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group). (607 aa)
SEMA3GSemaphorin 3G; Belongs to the semaphorin family. (777 aa)
G1LPZ3_AILMEUncharacterized protein. (541 aa)
CFL1Cofilin 1; Belongs to the actin-binding proteins ADF family. (226 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (924 aa)
DPYSDihydropyrimidinase. (434 aa)
PLXNB3Plexin B3. (1932 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (307 aa)
RHOBRas homolog family member B. (196 aa)
PKHD1Uncharacterized protein. (3386 aa)
ARHGAP35Rho GTPase activating protein 35. (1493 aa)
PLXNA2Plexin A2. (1894 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1546 aa)
ENSAMEP00000008181Heat shock protein HSP 90-alpha-like. (158 aa)
LIMK2LIM domain kinase 2. (617 aa)
RND1Rho family GTPase 1. (232 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1353 aa)
PLXNA1Plexin A1. (1837 aa)
TLNRD1Talin rod domain containing 1. (329 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (735 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (775 aa)
FYNTyrosine-protein kinase. (537 aa)
FARP2FERM, ARH/RhoGEF and pleckstrin domain protein 2. (1034 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1047 aa)
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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