STRINGSTRING
POLR2I POLR2I EP300 EP300 PRMT1 PRMT1 NCOA3 NCOA3 ZNF217 ZNF217 GTF2F2 GTF2F2 GATA3 GATA3 GREB1 GREB1 SP1 SP1 FOSB FOSB G1M0F9_AILME G1M0F9_AILME G1M038_AILME G1M038_AILME POLR2D POLR2D TRPS1 TRPS1 CXXC5 CXXC5 YY1 YY1 JUND JUND ESR1 ESR1 TNRC6B TNRC6B CARM1 CARM1 CREBBP CREBBP KANK2 KANK2 TBPL2 TBPL2 POLR2F POLR2F G1LUA4_AILME G1LUA4_AILME G1LU99_AILME G1LU99_AILME G1LU58_AILME G1LU58_AILME MYB MYB LOC100470602 LOC100470602 ZC3H12C ZC3H12C POLR2B POLR2B G1LN24_AILME G1LN24_AILME FOXA1 FOXA1 ENSAMEP00000008181 ENSAMEP00000008181 HDAC1 HDAC1 ERBB4 ERBB4 CCNT1 CCNT1 GTF2F1 GTF2F1 ZC3H12B ZC3H12B KANK1 KANK1 POLR2G POLR2G NCOA2 NCOA2 EBAG9 EBAG9 HSP90AA1 HSP90AA1 CITED1 CITED1 GTF2A2 GTF2A2 G1LGB9_AILME G1LGB9_AILME PRMT8 PRMT8 KANK3 KANK3 C11orf88 C11orf88 PTGES3 PTGES3 MED1 MED1 G1L9U8_AILME G1L9U8_AILME POLR2E POLR2E DDX5 DDX5 NCOA1 NCOA1 GREB1L GREB1L TFF3 TFF3 TFF1 TFF1 GTF2A1 GTF2A1 H3-3A H3-3A ZC3H12A ZC3H12A H2AZ1 H2AZ1 KAT2B KAT2B POLR2K POLR2K USF2 USF2 LOC100468404 LOC100468404 LOC100468151 LOC100468151 LOC100465110-8 LOC100465110-8 G1MNR5_AILME G1MNR5_AILME LOC100480024-10 LOC100480024-10 LOC100480024-9 LOC100480024-9 LOC100464367 LOC100464367 LOC100465110-7 LOC100465110-7 LOC100480024-8 LOC100480024-8 ENSAMEP00000020998 ENSAMEP00000020998 LOC100480024-7 LOC100480024-7 G1MNN7_AILME G1MNN7_AILME LOC100465110-6 LOC100465110-6 LOC100465110-5 LOC100465110-5 LOC100469449-2 LOC100469449-2 LOC100465110-4 LOC100465110-4 LOC100480024-6 LOC100480024-6 LOC100480024-5 LOC100480024-5 LOC100465110-3 LOC100465110-3 ENSAMEP00000020621 ENSAMEP00000020621 LOC100480024-4 LOC100480024-4 G1MMD8_AILME G1MMD8_AILME G1MM49_AILME G1MM49_AILME ENSAMEP00000020416 ENSAMEP00000020416 ENSAMEP00000020408 ENSAMEP00000020408 H4C14 H4C14 ZFP42 ZFP42 G1MM28_AILME G1MM28_AILME NRIP1 NRIP1 LOC100466624 LOC100466624 G1MJU4_AILME G1MJU4_AILME LOC100465110-2 LOC100465110-2 LOC100480024-3 LOC100480024-3 LOC100471214 LOC100471214 LOC100464112 LOC100464112 ENSAMEP00000019566 ENSAMEP00000019566 LOC100466870 LOC100466870 LOC100480024-2 LOC100480024-2 LOC100465110 LOC100465110 LOC100480024 LOC100480024 LOC100469449 LOC100469449 FOS FOS ZC3H12D ZC3H12D H2AZ2 H2AZ2 PGR PGR KAT5 KAT5 CBFB CBFB TBP TBP POLR2C POLR2C POLR2H POLR2H G1MDF8_AILME G1MDF8_AILME POLR2A POLR2A TBPL1 TBPL1 G1MBX7_AILME G1MBX7_AILME G1MBX0_AILME G1MBX0_AILME USF1 USF1 UPK3BL2 UPK3BL2 POLR2J POLR2J CDK9 CDK9 KDM1A KDM1A KANK4 KANK4 CHD1 CHD1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
POLR2IRNA polymerase II subunit I; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
EP300E1A binding protein p300. (2421 aa)
PRMT1Protein arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (374 aa)
NCOA3Nuclear receptor coactivator. (1414 aa)
ZNF217Zinc finger protein 217. (659 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
GATA3GATA binding protein 3. (414 aa)
GREB1Uncharacterized protein. (1961 aa)
SP1Sp1 transcription factor. (785 aa)
FOSBFosB proto-oncogene, AP-1 transcription factor subunit. (338 aa)
G1M0F9_AILMECARM1 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (385 aa)
G1M038_AILMEUncharacterized protein. (884 aa)
POLR2DRNA polymerase II subunit D. (144 aa)
TRPS1Transcriptional repressor GATA binding 1. (1294 aa)
CXXC5CXXC finger protein 5. (278 aa)
YY1Uncharacterized protein. (300 aa)
JUNDJunD proto-oncogene, AP-1 transcription factor subunit. (298 aa)
ESR1Estrogen receptor 1. (449 aa)
TNRC6BTrinucleotide repeat containing adaptor 6B. (1847 aa)
CARM1Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (558 aa)
CREBBPCREB binding protein. (2370 aa)
KANK2KN motif and ankyrin repeat domains 2. (856 aa)
TBPL2Uncharacterized protein. (263 aa)
POLR2FRNA polymerase II subunit F. (127 aa)
G1LUA4_AILMEHistone H3; Belongs to the histone H3 family. (135 aa)
G1LU99_AILMEHistone H2B; Belongs to the histone H2B family. (172 aa)
G1LU58_AILMEUncharacterized protein. (342 aa)
MYBMYB proto-oncogene, transcription factor. (761 aa)
LOC100470602Histone H3; Belongs to the histone H3 family. (136 aa)
ZC3H12CZinc finger CCCH-type containing 12C. (884 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1176 aa)
G1LN24_AILMEHistone H2B; Belongs to the histone H2B family. (137 aa)
FOXA1Forkhead box A1. (418 aa)
ENSAMEP00000008181Heat shock protein HSP 90-alpha-like. (158 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (485 aa)
ERBB4Receptor protein-tyrosine kinase. (1282 aa)
CCNT1Cyclin T1; Belongs to the cyclin family. (727 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (457 aa)
ZC3H12BZinc finger CCCH-type containing 12B. (634 aa)
KANK1KN motif and ankyrin repeat domains 1. (1352 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
NCOA2Nuclear receptor coactivator. (1464 aa)
EBAG9Receptor-binding cancer antigen expressed on SiSo cells; May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases. (213 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (735 aa)
CITED1Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (205 aa)
GTF2A2General transcription factor IIA subunit 2. (102 aa)
G1LGB9_AILMEHistone domain-containing protein; Belongs to the histone H2B family. (141 aa)
PRMT8Protein arginine methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (394 aa)
KANK3KN motif and ankyrin repeat domains 3. (668 aa)
C11orf88Chromosome 11 open reading frame 88. (177 aa)
PTGES3Prostaglandin E synthase 3. (153 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1583 aa)
G1L9U8_AILMEUncharacterized protein. (165 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (671 aa)
NCOA1Nuclear receptor coactivator. (1505 aa)
GREB1LGREB1 like retinoic acid receptor coactivator. (1925 aa)
TFF3Trefoil factor 3. (76 aa)
TFF1Trefoil factor 1. (85 aa)
GTF2A1General transcription factor IIA subunit 1. (376 aa)
H3-3AHistone H3.3. (136 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (596 aa)
H2AZ1Histone H2A; Belongs to the histone H2A family. (128 aa)
KAT2BLysine acetyltransferase 2B. (754 aa)
POLR2KRNA polymerase II subunit K. (58 aa)
USF2Upstream transcription factor 2, c-fos interacting. (326 aa)
LOC100468404Histone H2B; Belongs to the histone H2B family. (127 aa)
LOC100468151Histone H2B; Belongs to the histone H2B family. (127 aa)
LOC100465110-8Histone H4. (103 aa)
G1MNR5_AILMEHistone H2B; Belongs to the histone H2B family. (135 aa)
LOC100480024-10Histone H3.1. (136 aa)
LOC100480024-9Histone H3.1. (136 aa)
LOC100464367Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LOC100465110-7Histone H4. (103 aa)
LOC100480024-8Histone H3.1. (136 aa)
ENSAMEP00000020998annotation not available (98 aa)
LOC100480024-7Histone H3.1. (136 aa)
G1MNN7_AILMEHistone domain-containing protein. (136 aa)
LOC100465110-6Histone H4. (103 aa)
LOC100465110-5Histone H4. (103 aa)
LOC100469449-2Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC100465110-4Histone H4. (103 aa)
LOC100480024-6Histone H3.1. (136 aa)
LOC100480024-5Histone H3.1. (136 aa)
LOC100465110-3Histone H4. (103 aa)
ENSAMEP00000020621annotation not available (96 aa)
LOC100480024-4Histone H3.1. (136 aa)
G1MMD8_AILMEHistone domain-containing protein; Belongs to the histone H2B family. (126 aa)
G1MM49_AILMEHistone domain-containing protein; Belongs to the histone H2B family. (136 aa)
ENSAMEP00000020416annotation not available (107 aa)
ENSAMEP00000020408annotation not available (107 aa)
H4C14Histone H4. (103 aa)
ZFP42ZFP42 zinc finger protein. (304 aa)
G1MM28_AILMEHistone H2A; Belongs to the histone H2A family. (107 aa)
NRIP1Nuclear receptor interacting protein 1. (1157 aa)
LOC100466624Histone H2B type 2-E. (126 aa)
G1MJU4_AILMEHistone H3; Belongs to the histone H3 family. (133 aa)
LOC100465110-2Histone H4. (103 aa)
LOC100480024-3Histone H3.1. (136 aa)
LOC100471214Histone domain-containing protein; Belongs to the histone H2B family. (137 aa)
LOC100464112Histone H2B type 1. (126 aa)
ENSAMEP00000019566annotation not available (96 aa)
LOC100466870Histone domain-containing protein; Belongs to the histone H2B family. (124 aa)
LOC100480024-2Histone H3.1. (136 aa)
LOC100465110Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LOC100480024Histone H3; Belongs to the histone H3 family. (136 aa)
LOC100469449Histone domain-containing protein; Belongs to the histone H2B family. (126 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
ZC3H12DUncharacterized protein. (263 aa)
H2AZ2Histone H2A; Belongs to the histone H2A family. (127 aa)
PGRProgesterone receptor. (925 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa)
CBFBCore-binding factor subunit beta. (163 aa)
TBPTATA-box binding protein. (324 aa)
POLR2CRNA polymerase II subunit C. (275 aa)
POLR2HDNA-directed RNA polymerase II polypeptide H. (150 aa)
G1MDF8_AILMEUncharacterized protein. (390 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1973 aa)
TBPL1TATA-box binding protein like 1. (186 aa)
G1MBX7_AILMEHistone H2B; Belongs to the histone H2B family. (135 aa)
G1MBX0_AILMEHistone H2B; Belongs to the histone H2B family. (136 aa)
USF1Upstream transcription factor 1. (310 aa)
UPK3BL2Uncharacterized protein. (257 aa)
POLR2JRNA polymerase II subunit J. (127 aa)
CDK9Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (370 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (818 aa)
KANK4KN motif and ankyrin repeat domains 4. (1009 aa)
CHD1Chromodomain helicase DNA binding protein 1. (1780 aa)
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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