(15 nodes) Low-density lipoprotein-receptor YWTD domain network (Ailuropoda melanoleuca)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NID1	Nidogen 1. (1296 aa)
	NHLRC2	NHL repeat containing 2. (755 aa)
	NID2	Nidogen 2. (1395 aa)
	LRP6	LDL receptor related protein 6. (1463 aa)
	LRP5	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1586 aa)
	G1L0X8_AILME	Uncharacterized protein. (669 aa)
	LRP4	LDL receptor related protein 4. (1888 aa)
	SORL1	Sortilin related receptor 1. (2178 aa)
	LRP1	LDL receptor related protein 1. (4543 aa)
	LDLR	Low density lipoprotein receptor. (870 aa)
	LRP2	LDL receptor related protein 2. (4621 aa)
	LRP8	LDL receptor related protein 8. (964 aa)
	VLDLR	Very low density lipoprotein receptor. (873 aa)
	LRP1B	LDL receptor related protein 1B. (4451 aa)
	EGF	Epidermal growth factor. (864 aa)

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EGF	G1L0X8_AILME	ENSAMEP00000015773	ENSAMEP00000000530	Epidermal growth factor.	Uncharacterized protein.	0.407
EGF	LRP2	ENSAMEP00000015773	ENSAMEP00000011312	Epidermal growth factor.	LDL receptor related protein 2.	0.407
G1L0X8_AILME	EGF	ENSAMEP00000000530	ENSAMEP00000015773	Uncharacterized protein.	Epidermal growth factor.	0.407
LRP1	LRP2	ENSAMEP00000004987	ENSAMEP00000011312	LDL receptor related protein 1.	LDL receptor related protein 2.	0.905
LRP2	EGF	ENSAMEP00000011312	ENSAMEP00000015773	LDL receptor related protein 2.	Epidermal growth factor.	0.407
LRP2	LRP1	ENSAMEP00000011312	ENSAMEP00000004987	LDL receptor related protein 2.	LDL receptor related protein 1.	0.905
LRP5	LRP6	ENSAMEP00000001463	ENSAMEP00000002044	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	LDL receptor related protein 6.	0.865
LRP6	LRP5	ENSAMEP00000002044	ENSAMEP00000001463	LDL receptor related protein 6.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.865
LRP8	VLDLR	ENSAMEP00000010106	ENSAMEP00000012963	LDL receptor related protein 8.	Very low density lipoprotein receptor.	0.444
NID1	NID2	ENSAMEP00000003414	ENSAMEP00000002182	Nidogen 1.	Nidogen 2.	0.455
NID2	NID1	ENSAMEP00000002182	ENSAMEP00000003414	Nidogen 2.	Nidogen 1.	0.455
VLDLR	LRP8	ENSAMEP00000012963	ENSAMEP00000010106	Very low density lipoprotein receptor.	LDL receptor related protein 8.	0.444